Motif ID: Pou3f2

Z-value: 0.759


Transcription factors associated with Pou3f2:

Gene SymbolEntrez IDGene Name
Pou3f2 ENSMUSG00000095139.1 Pou3f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pou3f2mm10_v2_chr4_-_22488296_224883660.331.2e-01Click!


Activity profile for motif Pou3f2.

activity profile for motif Pou3f2


Sorted Z-values histogram for motif Pou3f2

Sorted Z-values for motif Pou3f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Pou3f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 112 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 2.392 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr7_+_51621830 2.186 ENSMUST00000032710.5
Slc17a6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr3_+_141465564 2.094 ENSMUST00000106236.2
ENSMUST00000075282.3
Unc5c

unc-5 homolog C (C. elegans)

chr19_+_60144682 1.746 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chr11_+_23256566 1.500 ENSMUST00000136235.1
Xpo1
exportin 1, CRM1 homolog (yeast)
chr12_+_52699297 1.246 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr3_+_141465592 1.216 ENSMUST00000130636.1
Unc5c
unc-5 homolog C (C. elegans)
chr4_-_110286581 1.133 ENSMUST00000138972.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr14_+_84443553 1.024 ENSMUST00000071370.5
Pcdh17
protocadherin 17
chr18_+_5593566 1.016 ENSMUST00000160910.1
Zeb1
zinc finger E-box binding homeobox 1
chr17_-_46032366 0.999 ENSMUST00000071648.5
ENSMUST00000142351.2
ENSMUST00000167860.1
Vegfa


vascular endothelial growth factor A


chr2_-_60125651 0.962 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr14_-_47418407 0.954 ENSMUST00000043296.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr14_-_88471396 0.946 ENSMUST00000061628.5
Pcdh20
protocadherin 20
chr17_-_46031813 0.931 ENSMUST00000024747.7
Vegfa
vascular endothelial growth factor A
chr11_+_23256001 0.873 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
Xpo1



exportin 1, CRM1 homolog (yeast)



chr14_+_99046406 0.828 ENSMUST00000022656.6
Bora
bora, aurora kinase A activator
chr2_-_136387929 0.814 ENSMUST00000035264.2
ENSMUST00000077200.3
Pak7

p21 protein (Cdc42/Rac)-activated kinase 7

chr1_+_150392794 0.805 ENSMUST00000124973.2
Tpr
translocated promoter region
chr3_+_88965812 0.792 ENSMUST00000090933.4
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 2.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.4 2.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 2.2 GO:0001504 neurotransmitter uptake(GO:0001504)
0.6 1.9 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.3 1.2 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 1.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 1.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.3 0.8 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.8 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 0.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.7 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.7 GO:0045059 positive thymic T cell selection(GO:0045059)
0.2 0.6 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.6 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.6 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.4 GO:0005642 annulate lamellae(GO:0005642)
0.0 2.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.9 GO:0005604 basement membrane(GO:0005604)
0.1 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.0 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 0.8 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.8 GO:0072687 meiotic spindle(GO:0072687)
0.2 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 2.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 2.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.6 1.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 1.2 GO:0043495 protein anchor(GO:0043495)
0.0 1.1 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.2 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.6 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2 0.5 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.5 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.5 GO:0052650 retinal binding(GO:0016918) NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0042974 retinoic acid receptor binding(GO:0042974)