Motif ID: Sox11

Z-value: 0.448


Transcription factors associated with Sox11:

Gene SymbolEntrez IDGene Name
Sox11 ENSMUSG00000063632.5 Sox11

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox11mm10_v2_chr12_-_27342696_273427260.511.2e-02Click!


Activity profile for motif Sox11.

activity profile for motif Sox11


Sorted Z-values histogram for motif Sox11

Sorted Z-values for motif Sox11



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox11

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_16378231 1.285 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr13_-_99516537 1.112 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr6_-_23248264 0.829 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr5_+_14514918 0.649 ENSMUST00000030691.10
ENSMUST00000182407.1
 Pclo

piccolo (presynaptic cytomatrix protein)

chr16_-_44558864 0.565 ENSMUST00000023370.4
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr15_+_76797628 0.504 ENSMUST00000165535.2
 Gm17271
predicted gene, 17271
chr16_-_50330987 0.502 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr3_+_134236483 0.488 ENSMUST00000181904.1
ENSMUST00000053048.9
 Cxxc4

CXXC finger 4

chr16_-_44558879 0.455 ENSMUST00000114634.1
 Boc
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr5_+_89028035 0.436 ENSMUST00000113216.2
ENSMUST00000134303.1
 Slc4a4

solute carrier family 4 (anion exchanger), member 4

chr2_+_154548888 0.426 ENSMUST00000045116.4
ENSMUST00000109709.3
 1700003F12Rik

RIKEN cDNA 1700003F12 gene

chr16_+_8830093 0.379 ENSMUST00000023150.5
 1810013L24Rik
RIKEN cDNA 1810013L24 gene
chr10_+_17796256 0.361 ENSMUST00000037964.6
 Txlnb
taxilin beta
chr5_-_131616599 0.356 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr14_-_47418407 0.323 ENSMUST00000043296.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr11_+_98937669 0.297 ENSMUST00000107475.2
ENSMUST00000068133.3
 Rara

retinoic acid receptor, alpha

chr5_+_89027959 0.295 ENSMUST00000130041.1
 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr11_+_24080664 0.286 ENSMUST00000118955.1
 Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr11_+_69364010 0.278 ENSMUST00000166700.1
 Gm17305
predicted gene, 17305
chr8_-_34965631 0.274 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr2_+_15055274 0.263 ENSMUST00000069870.3
 Arl5b
ADP-ribosylation factor-like 5B
chr6_-_12109583 0.259 ENSMUST00000080891.5
 Gm6578
predicted gene 6578
chr4_-_97584605 0.241 ENSMUST00000107067.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_-_97584612 0.234 ENSMUST00000107068.2
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr6_-_42693087 0.224 ENSMUST00000121083.1
 Fam115a
family with sequence similarity 115, member A
chr7_+_83631959 0.211 ENSMUST00000075418.7
ENSMUST00000117410.1
 Stard5

StAR-related lipid transfer (START) domain containing 5

chr8_-_83442648 0.204 ENSMUST00000167525.1
 Scoc
short coiled-coil protein
chr5_+_8046077 0.203 ENSMUST00000088786.4
 Sri
sorcin
chr1_+_82233112 0.196 ENSMUST00000023262.5
 Gm9747
predicted gene 9747
chr9_+_101074727 0.195 ENSMUST00000085177.3
 Msl2
male-specific lethal 2 homolog (Drosophila)
chr6_-_42693030 0.193 ENSMUST00000045140.4
 Fam115a
family with sequence similarity 115, member A
chr5_-_148552783 0.192 ENSMUST00000079324.7
ENSMUST00000164904.1
 Ubl3

ubiquitin-like 3

chr3_+_67430096 0.192 ENSMUST00000077271.6
ENSMUST00000161009.1
 Gfm1

G elongation factor, mitochondrial 1

chr7_-_55962466 0.188 ENSMUST00000032635.7
ENSMUST00000152649.1
 Nipa2

non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)

chr11_+_4873951 0.176 ENSMUST00000038570.2
 Nipsnap1
4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1 (C. elegans)
chr11_-_64436653 0.175 ENSMUST00000177999.1
 F930015N05Rik
RIKEN cDNA F930015N05 gene
chr1_+_44119952 0.175 ENSMUST00000114709.2
 Bivm
basic, immunoglobulin-like variable motif containing
chr14_-_52213379 0.173 ENSMUST00000140603.1
 Chd8
chromodomain helicase DNA binding protein 8
chr3_+_60877002 0.169 ENSMUST00000099086.2
 Gm8325
predicted pseudogene 8325
chr11_-_50292302 0.168 ENSMUST00000059458.4
 Maml1
mastermind like 1 (Drosophila)
chr9_+_107888129 0.167 ENSMUST00000035202.2
 Mon1a
MON1 homolog A (yeast)
chr5_+_121795034 0.156 ENSMUST00000162327.1
 Atxn2
ataxin 2
chr7_+_70388305 0.145 ENSMUST00000080024.5
 B130024G19Rik
RIKEN cDNA B130024G19 gene
chr13_+_40859768 0.142 ENSMUST00000110191.2
 Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr3_+_28805436 0.133 ENSMUST00000043867.5
 Rpl22l1
ribosomal protein L22 like 1
chr13_+_24327415 0.131 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr15_-_81104999 0.129 ENSMUST00000109579.2
 Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr2_-_86347764 0.128 ENSMUST00000099894.2
 Olfr1055
olfactory receptor 1055
chr16_+_65520503 0.128 ENSMUST00000176330.1
ENSMUST00000004964.8
ENSMUST00000176038.1
 Pou1f1


POU domain, class 1, transcription factor 1


chr2_+_3114220 0.126 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr10_-_76110956 0.125 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr4_-_44072578 0.118 ENSMUST00000173383.1
 Gne
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr9_+_52047150 0.117 ENSMUST00000163153.1
 Rdx
radixin
chr9_+_32116040 0.114 ENSMUST00000174641.1
 Arhgap32
Rho GTPase activating protein 32
chr2_-_156111954 0.112 ENSMUST00000142960.2
ENSMUST00000136296.2
ENSMUST00000059647.5
ENSMUST00000109604.2
ENSMUST00000138068.1
ENSMUST00000128499.1
 Cpne1

Rbm12



copine I

RNA binding motif protein 12



chr8_+_85432686 0.111 ENSMUST00000180883.1
 1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr6_-_136173492 0.105 ENSMUST00000111905.1
 Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr2_-_127247620 0.099 ENSMUST00000174030.1
ENSMUST00000174863.1
 Ciao1

cytosolic iron-sulfur protein assembly 1

chr9_+_65890237 0.087 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr17_+_43016536 0.080 ENSMUST00000024708.4
 Tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr10_+_24869982 0.074 ENSMUST00000092646.6
 Med23
mediator complex subunit 23
chr7_-_73541738 0.068 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chr11_-_69369377 0.052 ENSMUST00000092971.6
ENSMUST00000108661.1
 Chd3

chromodomain helicase DNA binding protein 3

chr17_-_29007925 0.052 ENSMUST00000009138.5
ENSMUST00000119274.1
 Stk38

serine/threonine kinase 38

chr7_-_105737376 0.051 ENSMUST00000098148.4
 Rrp8
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr2_-_36136773 0.040 ENSMUST00000028251.3
 Rbm18
RNA binding motif protein 18
chr10_+_115569986 0.035 ENSMUST00000173620.1
 A930009A15Rik
RIKEN cDNA A930009A15 gene
chr2_-_36136602 0.030 ENSMUST00000122456.1
 Rbm18
RNA binding motif protein 18
chr1_-_175491130 0.023 ENSMUST00000027812.5
 Rgs7
regulator of G protein signaling 7
chr5_+_144100387 0.019 ENSMUST00000041804.7
 Lmtk2
lemur tyrosine kinase 2
chr2_-_127247768 0.015 ENSMUST00000003759.4
 Ciao1
cytosolic iron-sulfur protein assembly 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.6 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.3 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.3 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 1.1 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.0 1.3 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 0.1 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 1.0 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.7 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:1902965 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.2 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0044316 cone cell pedicle(GO:0044316)
0.1 1.1 GO:0043196 varicosity(GO:0043196)
0.1 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)