Motif ID: Zbtb18

Z-value: 1.109


Transcription factors associated with Zbtb18:

Gene SymbolEntrez IDGene Name
Zbtb18 ENSMUSG00000063659.6 Zbtb18

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zbtb18mm10_v2_chr1_+_177445660_177445821-0.744.7e-05Click!


Activity profile for motif Zbtb18.

activity profile for motif Zbtb18


Sorted Z-values histogram for motif Zbtb18

Sorted Z-values for motif Zbtb18



Network of associatons between targets according to the STRING database.



First level regulatory network of Zbtb18

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_7555053 5.132 ENSMUST00000090679.2
ENSMUST00000184986.1
 Tac1

tachykinin 1

chr17_-_73710415 3.881 ENSMUST00000112591.2
ENSMUST00000024858.5
 Galnt14

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14

chr2_+_165655237 3.313 ENSMUST00000063433.7
 Eya2
eyes absent 2 homolog (Drosophila)
chr5_-_30945393 2.641 ENSMUST00000031051.6
 Cgref1
cell growth regulator with EF hand domain 1
chr18_+_50051702 2.638 ENSMUST00000134348.1
ENSMUST00000153873.2
 Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr4_-_141598206 2.507 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
 Fblim1


filamin binding LIM protein 1


chr10_+_127514939 2.371 ENSMUST00000035735.9
 Ndufa4l2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr13_+_13784278 2.332 ENSMUST00000021734.7
 Gng4
guanine nucleotide binding protein (G protein), gamma 4
chr4_+_43957678 2.272 ENSMUST00000107855.1
 Glipr2
GLI pathogenesis-related 2
chr12_+_109743787 2.085 ENSMUST00000183068.1
 Mirg
miRNA containing gene
chr4_+_43957401 2.083 ENSMUST00000030202.7
 Glipr2
GLI pathogenesis-related 2
chr19_+_47178820 2.081 ENSMUST00000111808.3
 Neurl1a
neuralized homolog 1A (Drosophila)
chr9_-_20976762 1.966 ENSMUST00000054197.5
 S1pr2
sphingosine-1-phosphate receptor 2
chr3_-_88458876 1.888 ENSMUST00000147200.1
ENSMUST00000169222.1
 Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr11_-_107794557 1.857 ENSMUST00000021066.3
 Cacng4
calcium channel, voltage-dependent, gamma subunit 4
chr3_-_88459047 1.819 ENSMUST00000165898.1
ENSMUST00000127436.1
 Sema4a

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

chr7_+_122671401 1.728 ENSMUST00000182095.1
 Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr3_+_134236483 1.682 ENSMUST00000181904.1
ENSMUST00000053048.9
 Cxxc4

CXXC finger 4

chr4_+_128883549 1.667 ENSMUST00000035667.8
 Trim62
tripartite motif-containing 62
chr15_-_79804717 1.635 ENSMUST00000023057.8
 Nptxr
neuronal pentraxin receptor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 148 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 5.1 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.2 5.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 4.7 GO:0030308 negative regulation of cell growth(GO:0030308)
0.2 3.7 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.5 3.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 3.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.1 3.1 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 2.6 GO:0032611 interleukin-1 beta production(GO:0032611)
0.2 2.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 2.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.7 2.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.2 2.0 GO:0060539 diaphragm development(GO:0060539)
0.1 1.7 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 1.7 GO:0007338 single fertilization(GO:0007338)
0.1 1.6 GO:0045760 positive regulation of action potential(GO:0045760)
0.2 1.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 1.4 GO:0022900 electron transport chain(GO:0022900)
0.4 1.3 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.3 1.3 GO:0070327 thyroid hormone transport(GO:0070327)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 3.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 3.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 2.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 2.4 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.7 GO:0097440 apical dendrite(GO:0097440)
0.3 1.6 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 1.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.4 1.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2 1.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.0 GO:0032009 early phagosome(GO:0032009)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 0.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.9 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 102 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 3.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 3.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 3.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 3.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 3.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.5 GO:0031005 filamin binding(GO:0031005)
0.0 2.1 GO:0045182 translation regulator activity(GO:0045182)
0.2 2.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.8 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.7 GO:0030165 PDZ domain binding(GO:0030165)
0.5 1.6 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 1.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 1.5 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.5 1.4 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 1.4 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.3 1.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.2 1.3 GO:0070324 thyroid hormone binding(GO:0070324)