Motif ID: Crem_Jdp2

Z-value: 0.497

Transcription factors associated with Crem_Jdp2:

Gene SymbolEntrez IDGene Name
Crem ENSMUSG00000063889.10 Crem
Jdp2 ENSMUSG00000034271.9 Jdp2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cremmm10_v2_chr18_-_3281036_3281132-0.213.3e-01Click!
Jdp2mm10_v2_chr12_+_85599047_855991050.019.5e-01Click!


Activity profile for motif Crem_Jdp2.

activity profile for motif Crem_Jdp2


Sorted Z-values histogram for motif Crem_Jdp2

Sorted Z-values for motif Crem_Jdp2



Network of associatons between targets according to the STRING database.



First level regulatory network of Crem_Jdp2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 5.922 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr17_+_43953191 2.028 ENSMUST00000044792.4
 Rcan2
regulator of calcineurin 2
chr19_-_5085483 1.875 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
 Tmem151a


transmembrane protein 151A


chr17_+_43952999 1.819 ENSMUST00000177857.1
 Rcan2
regulator of calcineurin 2
chr5_-_106458440 1.764 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr3_+_135212557 1.736 ENSMUST00000062893.7
 Cenpe
centromere protein E
chr3_+_125404072 1.663 ENSMUST00000173932.1
 Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr1_-_79440039 1.475 ENSMUST00000049972.4
 Scg2
secretogranin II
chr3_+_125404292 1.436 ENSMUST00000144344.1
 Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr16_-_16829276 1.416 ENSMUST00000023468.5
 Spag6
sperm associated antigen 6
chr7_-_142899985 1.410 ENSMUST00000000219.3
 Th
tyrosine hydroxylase
chr11_+_84525669 1.275 ENSMUST00000126072.1
ENSMUST00000128121.1
 1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr11_+_84525647 1.212 ENSMUST00000134800.1
 1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr11_-_84525514 1.204 ENSMUST00000018842.7
 Lhx1
LIM homeobox protein 1
chr2_+_109280738 1.187 ENSMUST00000028527.7
 Kif18a
kinesin family member 18A
chr2_+_143546144 1.181 ENSMUST00000028905.9
 Pcsk2
proprotein convertase subtilisin/kexin type 2
chr19_+_59260878 1.177 ENSMUST00000026084.3
 Slc18a2
solute carrier family 18 (vesicular monoamine), member 2
chr13_+_113035111 1.127 ENSMUST00000180543.1
ENSMUST00000181568.1
ENSMUST00000109244.2
ENSMUST00000181117.1
ENSMUST00000181741.1
 Cdc20b




cell division cycle 20B




chr8_-_24438937 1.065 ENSMUST00000052622.4
 1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr9_-_20976762 1.048 ENSMUST00000054197.5
 S1pr2
sphingosine-1-phosphate receptor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 126 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 5.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 3.8 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.4 2.6 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 1.7 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.3 1.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 1.5 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 1.4 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 1.3 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.4 1.2 GO:0060067 cervix development(GO:0060067) comma-shaped body morphogenesis(GO:0072049) S-shaped body morphogenesis(GO:0072050) anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.4 1.2 GO:0030070 insulin processing(GO:0030070)
0.1 1.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.1 1.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 1.2 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.1 1.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 1.1 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.3 1.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 1.0 GO:0001709 cell fate determination(GO:0001709)
0.1 0.9 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.8 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.2 2.7 GO:0031045 dense core granule(GO:0031045)
0.0 1.6 GO:0031513 nonmotile primary cilium(GO:0031513)
0.5 1.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.2 1.4 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.3 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.6 GO:0001940 male pronucleus(GO:0001940)
0.2 0.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.5 GO:0071437 invadopodium(GO:0071437)
0.1 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0097440 apical dendrite(GO:0097440)
0.0 0.5 GO:0005876 spindle microtubule(GO:0005876)
0.1 0.4 GO:1990423 RZZ complex(GO:1990423)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.6 3.8 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 3.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.4 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.5 GO:0042056 chemoattractant activity(GO:0042056)
0.2 1.4 GO:0035240 dopamine binding(GO:0035240)
0.2 1.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.4 1.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 1.0 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.1 0.7 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)