Motif ID: Scrt1

Z-value: 0.577


Transcription factors associated with Scrt1:

Gene SymbolEntrez IDGene Name
Scrt1 ENSMUSG00000048385.8 Scrt1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Scrt1mm10_v2_chr15_-_76521902_76522129-0.452.9e-02Click!


Activity profile for motif Scrt1.

activity profile for motif Scrt1


Sorted Z-values histogram for motif Scrt1

Sorted Z-values for motif Scrt1



Network of associatons between targets according to the STRING database.



First level regulatory network of Scrt1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_115163333 2.501 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr1_-_173942445 2.398 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr17_-_25570678 2.265 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr5_-_114273702 2.110 ENSMUST00000144050.1
ENSMUST00000044790.5
 Foxn4

forkhead box N4

chr18_-_82406777 1.524 ENSMUST00000065224.6
 Galr1
galanin receptor 1
chr11_-_55419898 1.460 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr5_+_118169712 1.452 ENSMUST00000054836.6
 Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr14_+_28511344 1.412 ENSMUST00000112272.1
 Wnt5a
wingless-related MMTV integration site 5A
chr15_-_66500857 1.384 ENSMUST00000023006.6
 Lrrc6
leucine rich repeat containing 6 (testis)
chr11_+_3332426 1.171 ENSMUST00000136474.1
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr13_-_81633119 1.112 ENSMUST00000126444.1
ENSMUST00000128585.1
ENSMUST00000146749.1
ENSMUST00000095585.4
 Gpr98



G protein-coupled receptor 98



chr8_-_71537402 1.093 ENSMUST00000051672.7
 Bst2
bone marrow stromal cell antigen 2
chr3_-_53657339 0.902 ENSMUST00000091137.4
 Frem2
Fras1 related extracellular matrix protein 2
chr3_+_90537242 0.900 ENSMUST00000098911.3
 S100a16
S100 calcium binding protein A16
chr3_+_90537306 0.879 ENSMUST00000107335.1
 S100a16
S100 calcium binding protein A16
chr7_-_25132473 0.861 ENSMUST00000108418.4
ENSMUST00000108415.3
ENSMUST00000098679.3
ENSMUST00000175774.2
ENSMUST00000108417.3
ENSMUST00000108416.3
ENSMUST00000108414.1
ENSMUST00000108413.1
ENSMUST00000176408.1
 Pou2f2








POU domain, class 2, transcription factor 2








chr16_-_17561240 0.838 ENSMUST00000065125.5
ENSMUST00000100123.3
ENSMUST00000023442.6
 4930451C15Rik


RIKEN cDNA 4930451C15 gene


chr4_-_45084538 0.801 ENSMUST00000052236.6
 Fbxo10
F-box protein 10
chr1_-_87156127 0.790 ENSMUST00000160810.1
 Ecel1
endothelin converting enzyme-like 1
chr12_-_119238794 0.788 ENSMUST00000026360.8
 Itgb8
integrin beta 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 2.5 GO:0042939 renal sodium ion transport(GO:0003096) glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 2.4 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.8 2.3 GO:0072034 renal vesicle induction(GO:0072034)
0.2 2.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 1.6 GO:0051592 response to calcium ion(GO:0051592)
0.5 1.5 GO:0051464 positive regulation of cortisol secretion(GO:0051464)
0.3 1.5 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.5 1.4 GO:1900020 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.2 1.4 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.2 1.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.3 1.1 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.2 1.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.1 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.9 GO:0048305 immunoglobulin secretion(GO:0048305)
0.3 0.8 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.3 0.8 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.8 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.8 GO:0003016 respiratory system process(GO:0003016)
0.2 0.7 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.1 0.7 GO:0048852 diencephalon morphogenesis(GO:0048852)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 1.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.4 1.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.4 GO:0005901 caveola(GO:0005901)
0.0 1.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.9 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.2 0.8 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 0.8 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.8 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.6 GO:0031012 extracellular matrix(GO:0031012)
0.1 0.5 GO:0097513 myosin II filament(GO:0097513)
0.0 0.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0000800 lateral element(GO:0000800)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.2 GO:0001047 core promoter binding(GO:0001047)
0.3 2.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 2.1 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 2.0 GO:0005518 collagen binding(GO:0005518)
0.5 1.5 GO:0004966 galanin receptor activity(GO:0004966)
0.5 1.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.4 1.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.0 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 0.7 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.6 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 0.5 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.5 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)