Motif ID: Nr2f2

Z-value: 0.997


Transcription factors associated with Nr2f2:

Gene SymbolEntrez IDGene Name
Nr2f2 ENSMUSG00000030551.7 Nr2f2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr2f2mm10_v2_chr7_-_70366735_70366771-0.311.5e-01Click!


Activity profile for motif Nr2f2.

activity profile for motif Nr2f2


Sorted Z-values histogram for motif Nr2f2

Sorted Z-values for motif Nr2f2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr2f2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_98053415 8.511 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr11_+_50602072 3.307 ENSMUST00000040523.8
 Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr5_+_64803513 2.882 ENSMUST00000165536.1
 Klf3
Kruppel-like factor 3 (basic)
chr3_-_85746266 2.681 ENSMUST00000118408.1
 Fam160a1
family with sequence similarity 160, member A1
chr13_-_96132568 2.640 ENSMUST00000161263.1
 Sv2c
synaptic vesicle glycoprotein 2c
chr3_-_116712198 2.354 ENSMUST00000120120.1
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr7_-_79386943 2.327 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr12_+_81026800 2.172 ENSMUST00000110347.2
ENSMUST00000021564.4
ENSMUST00000129362.1
 Smoc1


SPARC related modular calcium binding 1


chr5_-_71658308 2.115 ENSMUST00000031121.5
 Gabra4
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4
chr3_+_83766300 2.028 ENSMUST00000029625.7
 Sfrp2
secreted frizzled-related protein 2
chr7_+_48959089 1.974 ENSMUST00000183659.1
 Nav2
neuron navigator 2
chr11_-_54068932 1.691 ENSMUST00000093109.4
ENSMUST00000018755.3
 Pdlim4

PDZ and LIM domain 4

chr6_-_134632388 1.616 ENSMUST00000047443.3
 Mansc1
MANSC domain containing 1
chr9_+_51765325 1.591 ENSMUST00000065496.5
 Arhgap20
Rho GTPase activating protein 20
chr3_-_116711820 1.574 ENSMUST00000153108.1
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr2_+_22622183 1.506 ENSMUST00000028123.3
 Gad2
glutamic acid decarboxylase 2
chr3_-_116712644 1.446 ENSMUST00000029569.2
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr3_+_121723515 1.446 ENSMUST00000029771.8
 F3
coagulation factor III
chr3_-_132950043 1.432 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
 Npnt




nephronectin




chr14_+_76504478 1.411 ENSMUST00000022587.9
ENSMUST00000134109.1
 Tsc22d1

TSC22 domain family, member 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 154 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 5.4 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 3.3 GO:0030574 collagen catabolic process(GO:0030574)
0.1 3.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.4 2.9 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.2 2.6 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 2.4 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 2.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.3 2.1 GO:2001023 regulation of response to drug(GO:2001023)
0.3 2.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 2.1 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.7 2.0 GO:1904956 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.5 2.0 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.2 1.8 GO:0051608 histamine transport(GO:0051608)
0.1 1.7 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 1.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 1.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 1.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.5 1.4 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4 1.4 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 4.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.8 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 2.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 2.1 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 2.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.7 GO:0032587 ruffle membrane(GO:0032587)
0.4 1.6 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.4 1.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.3 1.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 1.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.3 1.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 1.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.1 GO:0031985 Golgi cisterna(GO:0031985)
0.2 1.0 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.4 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 5.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.8 GO:0005096 GTPase activator activity(GO:0005096)
0.1 3.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.7 2.9 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.3 2.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 2.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.4 2.3 GO:0019841 retinol binding(GO:0019841)
0.2 2.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 2.1 GO:0004890 GABA-A receptor activity(GO:0004890)
0.3 2.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.7 GO:0042805 actinin binding(GO:0042805)
0.0 1.7 GO:0051087 chaperone binding(GO:0051087)
0.0 1.7 GO:0008201 heparin binding(GO:0008201)
0.5 1.6 GO:0048039 ubiquinone binding(GO:0048039)
0.2 1.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.5 1.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.5 1.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.4 GO:0004896 cytokine receptor activity(GO:0004896)