Motif ID: Pax8

Z-value: 0.378


Transcription factors associated with Pax8:

Gene SymbolEntrez IDGene Name
Pax8 ENSMUSG00000026976.9 Pax8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax8mm10_v2_chr2_-_24475596_244756050.387.3e-02Click!


Activity profile for motif Pax8.

activity profile for motif Pax8


Sorted Z-values histogram for motif Pax8

Sorted Z-values for motif Pax8



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_42578588 1.501 ENSMUST00000179470.1
 Gm21028
predicted gene, 21028
chr7_+_112742025 0.923 ENSMUST00000164363.1
 Tead1
TEA domain family member 1
chr7_-_42706369 0.658 ENSMUST00000180131.1
 Gm17067
predicted gene 17067
chr11_-_69801716 0.358 ENSMUST00000011285.4
ENSMUST00000102585.1
 Fgf11

fibroblast growth factor 11

chr7_+_107595051 0.341 ENSMUST00000040056.7
 Ppfibp2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr12_+_71048338 0.299 ENSMUST00000135709.1
 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr18_-_12121460 0.298 ENSMUST00000055447.6
ENSMUST00000050228.7
ENSMUST00000092075.4
 Tmem241


transmembrane protein 241


chr13_-_62520451 0.285 ENSMUST00000082203.6
ENSMUST00000101547.4
 Zfp934

zinc finger protein 934

chr13_-_66852017 0.223 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr4_+_103313806 0.216 ENSMUST00000035780.3
 Oma1
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr1_+_165763746 0.215 ENSMUST00000111432.3
 Creg1
cellular repressor of E1A-stimulated genes 1
chr2_+_177508570 0.211 ENSMUST00000108940.2
 Gm14403
predicted gene 14403
chr9_-_103230415 0.201 ENSMUST00000035158.9
 Trf
transferrin
chr12_-_20900867 0.195 ENSMUST00000079237.5
 Zfp125
zinc finger protein 125
chr13_-_62777089 0.195 ENSMUST00000167516.2
 Gm5141
predicted gene 5141
chr13_-_62607499 0.193 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr1_+_65186727 0.184 ENSMUST00000097707.4
ENSMUST00000081154.7
 Pikfyve

phosphoinositide kinase, FYVE finger containing

chrX_+_82948861 0.155 ENSMUST00000114000.1
 Dmd
dystrophin, muscular dystrophy
chr17_+_45555693 0.143 ENSMUST00000024742.7
 Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr7_+_6961160 0.132 ENSMUST00000054055.6
 Usp29
ubiquitin specific peptidase 29
chr16_-_30587537 0.111 ENSMUST00000117363.2
 Lsg1
large subunit GTPase 1 homolog (S. cerevisiae)
chrX_-_105391726 0.109 ENSMUST00000142109.1
 5330434G04Rik
RIKEN cDNA 5330434G04 gene
chr13_+_108214389 0.102 ENSMUST00000022207.8
 Elovl7
ELOVL family member 7, elongation of long chain fatty acids (yeast)
chr2_+_128967383 0.102 ENSMUST00000110320.2
ENSMUST00000110319.2
 Zc3h6

zinc finger CCCH type containing 6

chr5_+_100196611 0.093 ENSMUST00000066813.1
 Gm9932
predicted gene 9932
chr9_-_103230262 0.092 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
 Trf

Gm20425
transferrin

predicted gene 20425
chr12_+_84996487 0.089 ENSMUST00000101202.3
 Ylpm1
YLP motif containing 1
chr7_+_114768736 0.067 ENSMUST00000117543.1
 Insc
inscuteable homolog (Drosophila)
chrX_-_7572843 0.059 ENSMUST00000132788.1
 Ppp1r3f
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr7_+_12897800 0.053 ENSMUST00000055528.4
ENSMUST00000117189.1
ENSMUST00000120809.1
ENSMUST00000119989.1
 Zscan22



zinc finger and SCAN domain containing 22



chr11_+_78499087 0.037 ENSMUST00000017488.4
 Vtn
vitronectin
chr1_+_74542881 0.034 ENSMUST00000113749.1
ENSMUST00000067916.6
ENSMUST00000113745.1
ENSMUST00000113747.1
ENSMUST00000113750.1
 Plcd4




phospholipase C, delta 4




chr2_-_150255591 0.033 ENSMUST00000063463.5
 Gm21994
predicted gene 21994
chr17_+_21691860 0.033 ENSMUST00000072133.4
 Gm10226
predicted gene 10226
chr19_+_46075842 0.017 ENSMUST00000165017.1
 Nolc1
nucleolar and coiled-body phosphoprotein 1
chr4_+_156215920 0.017 ENSMUST00000105572.1
 2310042D19Rik
RIKEN cDNA 2310042D19 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0014883 transition between fast and slow fiber(GO:0014883) positive regulation of stem cell population maintenance(GO:1902459)
0.1 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.3 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)