Motif ID: Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Z-value: 5.187

Transcription factors associated with Ybx1_Nfya_Nfyb_Nfyc_Cebpz:

Gene SymbolEntrez IDGene Name
Cebpz ENSMUSG00000024081.8 Cebpz
Nfya ENSMUSG00000023994.7 Nfya
Nfyb ENSMUSG00000020248.12 Nfyb
Nfyc ENSMUSG00000032897.11 Nfyc
Ybx1 ENSMUSG00000028639.8 Ybx1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfybmm10_v2_chr10_-_82764088_82764144-0.771.7e-05Click!
Ybx1mm10_v2_chr4_-_119294520_1192946040.683.4e-04Click!
Nfycmm10_v2_chr4_-_120825665_120825707-0.583.7e-03Click!
Cebpzmm10_v2_chr17_-_78937031_78937074-0.434.3e-02Click!
Nfyamm10_v2_chr17_-_48409729_484099060.174.4e-01Click!


Activity profile for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz.

activity profile for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz


Sorted Z-values histogram for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz

Sorted Z-values for motif Ybx1_Nfya_Nfyb_Nfyc_Cebpz



Network of associatons between targets according to the STRING database.



First level regulatory network of Ybx1_Nfya_Nfyb_Nfyc_Cebpz

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_17125106 25.418 ENSMUST00000093336.6
 2610318N02Rik
RIKEN cDNA 2610318N02 gene
chr14_+_46760526 19.597 ENSMUST00000067426.4
 Cdkn3
cyclin-dependent kinase inhibitor 3
chr8_+_83955507 19.204 ENSMUST00000005607.8
 Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr3_-_27153861 17.446 ENSMUST00000108300.1
ENSMUST00000108298.2
 Ect2

ect2 oncogene

chr7_-_120982260 16.994 ENSMUST00000033169.8
 Cdr2
cerebellar degeneration-related 2
chr3_-_27153844 16.681 ENSMUST00000176242.2
ENSMUST00000176780.1
 Ect2

ect2 oncogene

chr11_-_99024179 16.439 ENSMUST00000068031.7
 Top2a
topoisomerase (DNA) II alpha
chr3_-_8667033 15.991 ENSMUST00000042412.3
 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr6_+_124829582 15.540 ENSMUST00000024270.7
 Cdca3
cell division cycle associated 3
chr3_-_27153782 15.539 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
 Ect2


ect2 oncogene


chr6_+_17065129 14.950 ENSMUST00000115467.4
ENSMUST00000154266.2
ENSMUST00000076654.7
 Tes


testis derived transcript


chr8_+_57511833 14.419 ENSMUST00000067925.6
 Hmgb2
high mobility group box 2
chr2_+_164769892 14.018 ENSMUST00000088248.6
ENSMUST00000001439.6
 Ube2c

ubiquitin-conjugating enzyme E2C

chr3_-_89418287 13.150 ENSMUST00000029679.3
 Cks1b
CDC28 protein kinase 1b
chr17_-_24251382 13.132 ENSMUST00000115390.3
 Ccnf
cyclin F
chr3_+_105704599 12.973 ENSMUST00000066610.7
 Fam212b
family with sequence similarity 212, member B
chr14_-_67715585 12.781 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
 Cdca2


cell division cycle associated 2


chr13_-_56252163 12.358 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr2_+_34772089 12.133 ENSMUST00000028222.6
ENSMUST00000100171.2
 Hspa5

heat shock protein 5

chr1_+_139454747 11.462 ENSMUST00000053364.8
ENSMUST00000097554.3
 Aspm

asp (abnormal spindle)-like, microcephaly associated (Drosophila)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 563 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 90.3 GO:0007067 mitotic nuclear division(GO:0007067)
3.5 63.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
1.8 56.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.8 51.5 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.5 47.6 GO:0006342 chromatin silencing(GO:0006342)
2.4 33.4 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.5 26.7 GO:0006334 nucleosome assembly(GO:0006334)
3.8 26.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
1.6 25.5 GO:0030953 astral microtubule organization(GO:0030953)
1.2 25.2 GO:0051310 metaphase plate congression(GO:0051310)
2.2 24.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
1.0 21.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
1.2 20.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 19.8 GO:0044772 mitotic cell cycle phase transition(GO:0044772)
2.0 19.5 GO:0007100 mitotic centrosome separation(GO:0007100)
0.5 18.2 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.3 17.0 GO:0007019 microtubule depolymerization(GO:0007019)
4.1 16.4 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
2.9 14.7 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.5 14.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 251 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 58.5 GO:0000788 nuclear nucleosome(GO:0000788)
10.7 53.3 GO:0097149 centralspindlin complex(GO:0097149)
0.5 53.0 GO:0000776 kinetochore(GO:0000776)
0.4 37.4 GO:0005814 centriole(GO:0005814)
0.1 35.3 GO:0000790 nuclear chromatin(GO:0000790)
0.9 34.2 GO:0000786 nucleosome(GO:0000786)
0.7 29.4 GO:0005876 spindle microtubule(GO:0005876)
5.2 26.0 GO:0032133 chromosome passenger complex(GO:0032133)
1.0 26.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 25.3 GO:0005643 nuclear pore(GO:0005643)
1.9 24.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 24.0 GO:0016607 nuclear speck(GO:0016607)
0.1 23.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
2.7 21.7 GO:0005818 aster(GO:0005818)
1.6 21.3 GO:0031616 spindle pole centrosome(GO:0031616)
5.2 20.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.4 19.8 GO:0005871 kinesin complex(GO:0005871)
2.8 19.5 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.3 18.1 GO:0005657 replication fork(GO:0005657)
1.6 16.3 GO:0002178 palmitoyltransferase complex(GO:0002178)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 352 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 63.7 GO:0042393 histone binding(GO:0042393)
0.5 60.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 53.0 GO:0008017 microtubule binding(GO:0008017)
0.5 34.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.6 26.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.8 26.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 18.9 GO:0003777 microtubule motor activity(GO:0003777)
0.1 18.5 GO:0003682 chromatin binding(GO:0003682)
3.0 18.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
1.2 16.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.6 16.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.5 16.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
2.7 16.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.7 16.0 GO:0051787 misfolded protein binding(GO:0051787)
1.1 15.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.2 15.7 GO:0051082 unfolded protein binding(GO:0051082)
0.1 15.7 GO:0001047 core promoter binding(GO:0001047)
2.5 14.8 GO:0050786 RAGE receptor binding(GO:0050786)
4.8 14.5 GO:0035939 microsatellite binding(GO:0035939)
0.6 13.9 GO:0032183 SUMO binding(GO:0032183)