Motif ID: Foxd1
Z-value: 2.310
Transcription factors associated with Foxd1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxd1 | ENSMUSG00000078302.3 | Foxd1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxd1 | mm10_v2_chr13_+_98354234_98354250 | -0.45 | 3.0e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.9 | 65.0 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 5.4 | 26.8 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 3.3 | 23.4 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 2.2 | 6.7 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 2.0 | 5.9 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 1.9 | 5.7 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 1.8 | 12.3 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 1.7 | 7.0 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 1.7 | 6.7 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 1.4 | 4.3 | GO:1902524 | negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
| 1.3 | 3.9 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 1.2 | 3.6 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 1.2 | 5.8 | GO:0050847 | progesterone receptor signaling pathway(GO:0050847) |
| 1.1 | 3.3 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 1.1 | 9.8 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
| 1.0 | 3.1 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
| 1.0 | 9.5 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.9 | 13.2 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.9 | 3.7 | GO:0015886 | heme transport(GO:0015886) |
| 0.9 | 4.5 | GO:2000668 | dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) |
| 0.8 | 4.0 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.8 | 2.4 | GO:1901254 | positive regulation of intracellular transport of viral material(GO:1901254) |
| 0.8 | 2.4 | GO:2000598 | regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599) |
| 0.8 | 6.4 | GO:0071732 | cellular response to nitric oxide(GO:0071732) |
| 0.7 | 2.2 | GO:0043379 | memory T cell differentiation(GO:0043379) |
| 0.7 | 2.9 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.7 | 9.3 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.7 | 5.7 | GO:0002347 | response to tumor cell(GO:0002347) |
| 0.7 | 3.5 | GO:0032911 | nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.7 | 4.8 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 0.7 | 2.0 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) |
| 0.7 | 2.6 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.7 | 10.4 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.6 | 3.2 | GO:0071476 | cellular hypotonic response(GO:0071476) |
| 0.6 | 2.5 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
| 0.6 | 1.8 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.6 | 7.6 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.6 | 2.8 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.5 | 2.6 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.5 | 3.6 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.5 | 4.0 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.5 | 2.5 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 0.5 | 2.5 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.5 | 2.0 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.5 | 4.2 | GO:0035887 | aortic smooth muscle cell differentiation(GO:0035887) |
| 0.5 | 1.8 | GO:0070425 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) |
| 0.4 | 1.8 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 0.4 | 6.0 | GO:0003215 | cardiac right ventricle morphogenesis(GO:0003215) |
| 0.4 | 1.6 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.4 | 7.5 | GO:0002495 | antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504) |
| 0.4 | 1.2 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
| 0.4 | 1.1 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.4 | 2.6 | GO:2000258 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
| 0.4 | 2.6 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
| 0.4 | 0.4 | GO:1905005 | regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005) |
| 0.4 | 1.9 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.4 | 1.1 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.4 | 3.3 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.4 | 1.1 | GO:0048014 | Tie signaling pathway(GO:0048014) |
| 0.3 | 3.0 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.3 | 1.6 | GO:0008355 | olfactory learning(GO:0008355) |
| 0.3 | 2.5 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.3 | 4.7 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.3 | 5.3 | GO:0097154 | GABAergic neuron differentiation(GO:0097154) |
| 0.3 | 1.8 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.3 | 2.3 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.3 | 3.0 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.2 | 3.5 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.2 | 2.1 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.2 | 5.8 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.2 | 0.7 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
| 0.2 | 3.0 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.2 | 4.1 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.2 | 3.2 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.2 | 1.3 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
| 0.2 | 1.0 | GO:2000973 | regulation of pro-B cell differentiation(GO:2000973) |
| 0.2 | 2.4 | GO:0050901 | leukocyte tethering or rolling(GO:0050901) |
| 0.2 | 3.0 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.2 | 6.4 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.2 | 2.5 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.2 | 8.8 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.1 | 1.4 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.1 | 0.5 | GO:0034239 | regulation of macrophage fusion(GO:0034239) |
| 0.1 | 0.6 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 0.8 | GO:0007144 | female meiosis I(GO:0007144) |
| 0.1 | 2.2 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 2.2 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.1 | 1.2 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.1 | 1.3 | GO:0043970 | histone H3-K9 acetylation(GO:0043970) |
| 0.1 | 1.3 | GO:0070842 | aggresome assembly(GO:0070842) |
| 0.1 | 1.6 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.1 | 0.5 | GO:0010616 | negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of protein glycosylation(GO:0060051) |
| 0.1 | 0.5 | GO:0002667 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) negative regulation of protein kinase C signaling(GO:0090038) |
| 0.1 | 3.9 | GO:1900449 | regulation of glutamate receptor signaling pathway(GO:1900449) |
| 0.1 | 0.7 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 4.4 | GO:0046326 | positive regulation of glucose import(GO:0046326) |
| 0.1 | 3.4 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.1 | 1.4 | GO:0036230 | granulocyte activation(GO:0036230) |
| 0.1 | 3.1 | GO:0007026 | negative regulation of microtubule depolymerization(GO:0007026) |
| 0.1 | 1.3 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 6.0 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 10.0 | GO:0030010 | establishment of cell polarity(GO:0030010) |
| 0.1 | 0.6 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.1 | 1.8 | GO:0002931 | response to ischemia(GO:0002931) |
| 0.1 | 0.5 | GO:0000467 | exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) |
| 0.1 | 0.3 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
| 0.1 | 1.3 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 3.2 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.1 | 3.6 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 1.1 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.1 | 0.7 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.0 | 0.1 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.0 | 0.6 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 0.2 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.0 | 0.6 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.9 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.0 | 0.8 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 1.3 | GO:0000245 | spliceosomal complex assembly(GO:0000245) |
| 0.0 | 0.2 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.6 | GO:0045604 | regulation of epidermal cell differentiation(GO:0045604) |
| 0.0 | 0.3 | GO:0055012 | ventricular cardiac muscle cell differentiation(GO:0055012) |
| 0.0 | 0.4 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.1 | GO:0071168 | protein localization to chromatin(GO:0071168) |
| 0.0 | 1.1 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 0.6 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.0 | 0.1 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 0.9 | GO:0007052 | mitotic spindle organization(GO:0007052) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 5.9 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 1.2 | 4.7 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.8 | 6.7 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.8 | 2.4 | GO:0042025 | viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 0.7 | 2.2 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 0.6 | 5.1 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.6 | 9.3 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.5 | 7.6 | GO:0042555 | MCM complex(GO:0042555) |
| 0.4 | 1.1 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.3 | 6.0 | GO:0043657 | host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) |
| 0.3 | 1.8 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.2 | 7.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.2 | 3.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.2 | 3.0 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 4.2 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.2 | 3.5 | GO:0012510 | trans-Golgi network transport vesicle membrane(GO:0012510) |
| 0.2 | 7.3 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.2 | 0.8 | GO:0005712 | chiasma(GO:0005712) |
| 0.2 | 2.2 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.2 | 1.6 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.2 | 4.0 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 2.5 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.1 | 2.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 6.0 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.1 | 3.9 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 1.2 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.1 | 4.9 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.1 | 5.7 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.1 | 1.4 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 0.5 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.1 | 0.6 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 1.8 | GO:0005921 | gap junction(GO:0005921) |
| 0.1 | 2.6 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 3.2 | GO:0016459 | myosin complex(GO:0016459) |
| 0.1 | 2.5 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 23.2 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 3.3 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 2.4 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 3.2 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 5.2 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 3.0 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 2.5 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 2.3 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.9 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 6.1 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 1.2 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 1.1 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 2.0 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.0 | 6.5 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.1 | GO:0000798 | nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991) |
| 0.0 | 1.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 4.9 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 6.9 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 10.4 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.9 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 5.6 | GO:0031252 | cell leading edge(GO:0031252) |
| 0.0 | 39.2 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.0 | 1.3 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 1.1 | GO:0030532 | small nuclear ribonucleoprotein complex(GO:0030532) |
| 0.0 | 2.2 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 2.0 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.0 | 25.6 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.0 | 1.1 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 26.8 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.0 | 13.6 | GO:0005739 | mitochondrion(GO:0005739) |
| 0.0 | 2.9 | GO:0005874 | microtubule(GO:0005874) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.3 | 65.0 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 7.8 | 23.4 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 2.4 | 9.5 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 1.9 | 5.7 | GO:0035175 | histone kinase activity (H3-S10 specific)(GO:0035175) |
| 1.6 | 4.9 | GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) |
| 1.5 | 9.1 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 1.4 | 5.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 1.3 | 6.7 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.9 | 3.7 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.9 | 3.6 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.8 | 2.5 | GO:0003963 | RNA-3'-phosphate cyclase activity(GO:0003963) |
| 0.8 | 12.3 | GO:0008430 | selenium binding(GO:0008430) |
| 0.7 | 3.7 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.7 | 2.1 | GO:0005118 | sevenless binding(GO:0005118) |
| 0.7 | 4.0 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.6 | 2.8 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.5 | 3.2 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.5 | 2.6 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.5 | 3.0 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.5 | 3.5 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
| 0.5 | 2.0 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.5 | 2.4 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.5 | 1.4 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.5 | 1.4 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.5 | 1.9 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.5 | 1.8 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.5 | 6.8 | GO:0070888 | E-box binding(GO:0070888) |
| 0.5 | 4.5 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.4 | 3.9 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.4 | 6.4 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.4 | 2.0 | GO:0071253 | connexin binding(GO:0071253) |
| 0.4 | 9.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.4 | 3.5 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.3 | 2.5 | GO:0090482 | vitamin transmembrane transporter activity(GO:0090482) |
| 0.3 | 4.8 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.3 | 4.3 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.3 | 1.1 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.3 | 1.6 | GO:0008294 | calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294) |
| 0.3 | 4.8 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.3 | 2.3 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.2 | 6.4 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.2 | 2.4 | GO:0004622 | lysophospholipase activity(GO:0004622) |
| 0.2 | 0.8 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.2 | 3.8 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.2 | 2.6 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.2 | 2.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.2 | 0.5 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
| 0.2 | 1.8 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.2 | 5.9 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 3.6 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 3.1 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 7.6 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.1 | 1.1 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.1 | 0.9 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 9.8 | GO:0003823 | antigen binding(GO:0003823) |
| 0.1 | 3.7 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 0.4 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.1 | 2.5 | GO:0042287 | MHC protein binding(GO:0042287) |
| 0.1 | 5.1 | GO:0045502 | dynein binding(GO:0045502) |
| 0.1 | 4.2 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.1 | 6.4 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.1 | 0.9 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.1 | 2.2 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 0.6 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 0.7 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 2.4 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 6.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 3.1 | GO:0031690 | adrenergic receptor binding(GO:0031690) |
| 0.1 | 0.5 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 3.1 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.1 | 2.7 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.1 | 2.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 5.0 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.1 | 5.2 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.1 | 2.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 0.7 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.1 | 3.0 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 3.2 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 0.6 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.1 | 1.9 | GO:0052771 | coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771) |
| 0.1 | 1.8 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
| 0.1 | 0.5 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 2.2 | GO:0032934 | cholesterol binding(GO:0015485) sterol binding(GO:0032934) |
| 0.1 | 0.3 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.1 | 2.2 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
| 0.0 | 8.9 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 0.3 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 0.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.9 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 1.6 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 13.3 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 1.8 | GO:0044212 | transcription regulatory region DNA binding(GO:0044212) |
| 0.0 | 2.5 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
| 0.0 | 2.0 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 0.0 | 0.2 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.0 | 1.8 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 1.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.9 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.2 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.0 | 0.6 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 0.9 | GO:0004714 | transmembrane receptor protein tyrosine kinase activity(GO:0004714) |
| 0.0 | 0.5 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
