Motif ID: Foxd1

Z-value: 2.310


Transcription factors associated with Foxd1:

Gene SymbolEntrez IDGene Name
Foxd1 ENSMUSG00000078302.3 Foxd1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxd1mm10_v2_chr13_+_98354234_98354250-0.453.0e-02Click!


Activity profile for motif Foxd1.

activity profile for motif Foxd1


Sorted Z-values histogram for motif Foxd1

Sorted Z-values for motif Foxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Foxd1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144892813 26.077 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr4_+_144893077 20.816 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_+_144893127 18.149 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr16_-_22439719 15.029 ENSMUST00000079601.6
 Etv5
ets variant gene 5
chr8_-_84773381 13.226 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr10_-_8518801 13.145 ENSMUST00000061601.7
 Ust
uronyl-2-sulfotransferase
chr15_+_3270767 12.346 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr16_-_22439570 11.768 ENSMUST00000170393.1
 Etv5
ets variant gene 5
chr14_-_18239053 10.132 ENSMUST00000090543.5
 Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr7_+_141476374 9.825 ENSMUST00000117634.1
 Tspan4
tetraspanin 4
chr11_+_3332426 9.720 ENSMUST00000136474.1
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr18_+_69344503 9.515 ENSMUST00000114985.3
 Tcf4
transcription factor 4
chr8_+_65618009 7.520 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
 March1


membrane-associated ring finger (C3HC4) 1


chr11_+_3330781 6.995 ENSMUST00000136536.1
ENSMUST00000093399.4
 Pik3ip1

phosphoinositide-3-kinase interacting protein 1

chr13_-_93499803 6.749 ENSMUST00000065537.7
 Jmy
junction-mediating and regulatory protein
chr7_+_113207465 6.720 ENSMUST00000047321.7
 Arntl
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_3330401 6.703 ENSMUST00000045153.4
 Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr18_+_5593566 6.683 ENSMUST00000160910.1
 Zeb1
zinc finger E-box binding homeobox 1
chr3_+_52268337 6.422 ENSMUST00000053764.5
 Foxo1
forkhead box O1
chr2_+_38511643 6.369 ENSMUST00000054234.3
ENSMUST00000112902.1
ENSMUST00000112895.1
 Nek6


NIMA (never in mitosis gene a)-related expressed kinase 6



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 127 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.9 65.0 GO:0042572 retinol metabolic process(GO:0042572)
5.4 26.8 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
3.3 23.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.9 13.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
1.8 12.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.7 10.4 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.1 10.0 GO:0030010 establishment of cell polarity(GO:0030010)
1.1 9.8 GO:0048752 semicircular canal morphogenesis(GO:0048752)
1.0 9.5 GO:0042118 endothelial cell activation(GO:0042118)
0.7 9.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 8.8 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.6 7.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 7.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
1.7 7.0 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
2.2 6.7 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
1.7 6.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.8 6.4 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.2 6.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.4 6.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 6.0 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 39.2 GO:0070062 extracellular exosome(GO:0070062)
0.0 26.8 GO:0016021 integral component of membrane(GO:0016021)
0.0 25.6 GO:0005654 nucleoplasm(GO:0005654)
0.1 23.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 13.6 GO:0005739 mitochondrion(GO:0005739)
0.0 10.4 GO:0005925 focal adhesion(GO:0005925)
0.6 9.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.5 7.6 GO:0042555 MCM complex(GO:0042555)
0.2 7.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 7.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 6.9 GO:0031012 extracellular matrix(GO:0031012)
0.8 6.7 GO:0033391 chromatoid body(GO:0033391)
0.0 6.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 6.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.3 6.0 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 6.0 GO:0045171 intercellular bridge(GO:0045171)
2.0 5.9 GO:0005588 collagen type V trimer(GO:0005588)
0.1 5.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 5.6 GO:0031252 cell leading edge(GO:0031252)
0.0 5.2 GO:0005769 early endosome(GO:0005769)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
9.3 65.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
7.8 23.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 13.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.8 12.3 GO:0008430 selenium binding(GO:0008430)
0.1 9.8 GO:0003823 antigen binding(GO:0003823)
2.4 9.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.4 9.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
1.5 9.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 8.9 GO:0003713 transcription coactivator activity(GO:0003713)
0.1 7.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.5 6.8 GO:0070888 E-box binding(GO:0070888)
1.3 6.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 6.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 6.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 6.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 6.4 GO:0019894 kinesin binding(GO:0019894)
0.2 5.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
1.4 5.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.9 5.7 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.1 5.2 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)