Motif ID: Rest

Z-value: 1.951


Transcription factors associated with Rest:

Gene SymbolEntrez IDGene Name
Rest ENSMUSG00000029249.9 Rest

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Restmm10_v2_chr5_+_77265454_772655490.424.7e-02Click!


Activity profile for motif Rest.

activity profile for motif Rest


Sorted Z-values histogram for motif Rest

Sorted Z-values for motif Rest



Network of associatons between targets according to the STRING database.



First level regulatory network of Rest

PNG image of the network

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Top targets:


Showing 1 to 20 of 72 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_42255704 11.631 ENSMUST00000087123.5
 Golga7b
golgi autoantigen, golgin subfamily a, 7B
chr16_-_23890805 10.925 ENSMUST00000004480.3
 Sst
somatostatin
chr6_-_121473630 10.001 ENSMUST00000046373.5
 Iqsec3
IQ motif and Sec7 domain 3
chr5_-_121009510 9.512 ENSMUST00000079204.5
 Rph3a
rabphilin 3A
chr2_-_28916412 9.015 ENSMUST00000050776.2
ENSMUST00000113849.1
 Barhl1

BarH-like 1 (Drosophila)

chr6_+_8948608 7.258 ENSMUST00000160300.1
 Nxph1
neurexophilin 1
chr12_-_112511136 6.364 ENSMUST00000066791.5
 Tmem179
transmembrane protein 179
chr4_-_153482768 6.259 ENSMUST00000105646.2
 Ajap1
adherens junction associated protein 1
chr1_-_84696182 5.873 ENSMUST00000049126.6
 Dner
delta/notch-like EGF-related receptor
chr2_-_28916668 4.869 ENSMUST00000113847.1
 Barhl1
BarH-like 1 (Drosophila)
chr15_-_76521902 4.219 ENSMUST00000164703.1
ENSMUST00000096365.3
 Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr13_-_23991158 3.928 ENSMUST00000021770.7
 Scgn
secretagogin, EF-hand calcium binding protein
chr4_+_15881255 3.732 ENSMUST00000029876.1
 Calb1
calbindin 1
chr7_+_122671401 3.567 ENSMUST00000182095.1
 Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr1_+_34579693 3.458 ENSMUST00000052670.8
 Amer3
APC membrane recruitment 3
chr13_-_54749849 3.418 ENSMUST00000135343.1
 Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr7_+_122671378 3.223 ENSMUST00000182563.1
 Cacng3
calcium channel, voltage-dependent, gamma subunit 3
chr13_-_54749627 3.186 ENSMUST00000099506.1
 Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr11_-_35798884 3.113 ENSMUST00000160726.2
 Fbll1
fibrillarin-like 1
chr19_+_22139028 3.091 ENSMUST00000099569.2
ENSMUST00000087576.4
ENSMUST00000074770.5
 Trpm3


transient receptor potential cation channel, subfamily M, member 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 14.6 GO:0030901 midbrain development(GO:0030901)
0.3 10.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.4 10.0 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 6.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.5 5.9 GO:0007220 Notch receptor processing(GO:0007220)
0.5 4.6 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.1 4.2 GO:2001222 regulation of neuron migration(GO:2001222)
1.2 3.7 GO:1900673 olefin metabolic process(GO:1900673)
0.2 3.7 GO:0007614 short-term memory(GO:0007614)
0.2 3.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.6 3.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 2.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.5 2.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 2.2 GO:0071625 vocalization behavior(GO:0071625)
0.0 2.2 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.4 2.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.7 2.0 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.7 2.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.3 1.9 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.3 1.7 GO:0072318 clathrin coat disassembly(GO:0072318)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 7.9 GO:0043025 neuronal cell body(GO:0043025)
0.2 6.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 5.9 GO:0005769 early endosome(GO:0005769)
0.3 4.6 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 4.0 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.9 3.7 GO:0044307 dendritic branch(GO:0044307)
0.4 3.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.6 2.8 GO:0032426 stereocilium tip(GO:0032426)
0.0 2.5 GO:0043195 terminal bouton(GO:0043195)
0.0 2.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.3 1.9 GO:0008091 spectrin(GO:0008091)
0.0 1.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 1.0 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:1904115 axon cytoplasm(GO:1904115)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 16.4 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 13.6 GO:0005179 hormone activity(GO:0005179)
0.3 10.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
1.0 9.5 GO:0042301 phosphate ion binding(GO:0042301)
0.1 7.0 GO:0051219 phosphoprotein binding(GO:0051219)
0.2 6.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 5.9 GO:0005112 Notch binding(GO:0005112)
0.1 5.7 GO:0043178 alcohol binding(GO:0043178)
0.7 4.6 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.2 3.9 GO:0030506 ankyrin binding(GO:0030506)
0.3 3.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 3.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 3.1 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 2.8 GO:0046332 SMAD binding(GO:0046332)
0.2 2.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 2.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 1.0 GO:0001786 phosphatidylserine binding(GO:0001786)