Motif ID: Rhox4e_Rhox6_Vax2

Z-value: 1.497

Transcription factors associated with Rhox4e_Rhox6_Vax2:

Gene SymbolEntrez IDGene Name
Rhox4e ENSMUSG00000071770.4 Rhox4e
Rhox6 ENSMUSG00000006200.3 Rhox6
Vax2 ENSMUSG00000034777.1 Vax2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Vax2mm10_v2_chr6_+_83711232_83711288-0.174.4e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Rhox4e_Rhox6_Vax2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 26.851 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chrX_-_60893430 10.626 ENSMUST00000135107.2
Sox3
SRY-box containing gene 3
chr8_+_45658666 6.575 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
Sorbs2


sorbin and SH3 domain containing 2


chr8_+_45658731 6.394 ENSMUST00000143820.1
ENSMUST00000132139.1
Sorbs2

sorbin and SH3 domain containing 2

chr15_-_67113909 5.534 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr1_-_89933290 5.532 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr13_-_102906046 5.065 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_+_55782500 4.999 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr4_+_15881255 4.987 ENSMUST00000029876.1
Calb1
calbindin 1
chr13_-_102905740 4.391 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr7_-_25005895 4.321 ENSMUST00000102858.3
ENSMUST00000080882.6
Atp1a3

ATPase, Na+/K+ transporting, alpha 3 polypeptide

chr9_+_53771499 4.126 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr9_+_102720287 3.742 ENSMUST00000130602.1
Amotl2
angiomotin-like 2
chr12_-_112511136 3.682 ENSMUST00000066791.5
Tmem179
transmembrane protein 179
chr3_-_86548268 3.599 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr14_+_5517172 3.333 ENSMUST00000178220.1
Gm3488
predicted gene, 3488
chr14_+_5164535 3.333 ENSMUST00000179659.1
Gm3317
predicted gene 3317
chr12_+_109545390 3.101 ENSMUST00000146701.1
Meg3
maternally expressed 3
chr12_-_40037387 3.077 ENSMUST00000146905.1
Arl4a
ADP-ribosylation factor-like 4A
chr16_-_42340595 3.076 ENSMUST00000102817.4
Gap43
growth associated protein 43
chr8_+_45507768 3.006 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
Sorbs2





sorbin and SH3 domain containing 2





chr2_+_25372315 2.935 ENSMUST00000028329.6
ENSMUST00000114293.2
ENSMUST00000100323.2
Sapcd2


suppressor APC domain containing 2


chrX_-_23266751 2.860 ENSMUST00000115316.2
Klhl13
kelch-like 13
chr10_-_8886033 2.811 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr14_+_3667518 2.729 ENSMUST00000112801.3
Gm3020
predicted gene 3020
chr1_+_109983737 2.700 ENSMUST00000172005.1
Cdh7
cadherin 7, type 2
chr14_+_4198185 2.648 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr1_+_72284367 2.577 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr14_-_5863663 2.561 ENSMUST00000178594.1
Gm8237
predicted gene 8237
chr3_+_40800778 2.558 ENSMUST00000169566.1
Plk4
polo-like kinase 4
chr14_-_6411578 2.496 ENSMUST00000179312.1
Gm3591
predicted gene 3591
chr2_-_168767136 2.437 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr14_-_7473073 2.412 ENSMUST00000167833.2
Gm3752
predicted gene 3752
chr14_-_6874257 2.390 ENSMUST00000178298.1
ENSMUST00000179374.1
Gm3667
Gm3629
predicted gene 3667
predicted gene 3629
chr14_+_3348089 2.377 ENSMUST00000178722.1
Gm2956
predicted gene 2956
chr8_-_61902669 2.346 ENSMUST00000121785.1
ENSMUST00000034057.7
Palld

palladin, cytoskeletal associated protein

chr14_+_3428103 2.336 ENSMUST00000178060.1
Gm3005
predicted gene 3005
chr10_-_33951190 2.308 ENSMUST00000048222.4
Zufsp
zinc finger with UFM1-specific peptidase domain
chr14_+_4741737 2.285 ENSMUST00000178748.1
Gm3252
predicted gene 3252
chr14_+_4126066 2.236 ENSMUST00000167397.2
Gm8108
predicted gene 8108
chr14_+_4514758 2.206 ENSMUST00000112776.2
Gm3173
predicted gene 3173
chrX_+_9885622 2.170 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr2_+_65845767 2.155 ENSMUST00000122912.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chrM_+_7759 2.118 ENSMUST00000082407.1
ENSMUST00000082408.1
mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr14_+_3825596 2.105 ENSMUST00000178256.1
Gm3002
predicted gene 3002
chr14_+_4871156 2.103 ENSMUST00000166410.2
Gm3264
predicted gene 3264
chr14_-_6266620 2.050 ENSMUST00000096172.5
Gm3411
predicted gene 3411
chr14_+_4430992 2.003 ENSMUST00000164603.1
ENSMUST00000166848.1
Gm3173

predicted gene 3173

chr14_-_19569553 1.900 ENSMUST00000112595.2
Gm2237
predicted gene 2237
chr18_+_4993795 1.859 ENSMUST00000153016.1
Svil
supervillin
chr4_-_43499608 1.829 ENSMUST00000136005.1
ENSMUST00000054538.6
Arhgef39

Rho guanine nucleotide exchange factor (GEF) 39

chr19_+_23723279 1.813 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr14_+_4665094 1.786 ENSMUST00000169675.2
Gm3239
predicted gene 3239
chr14_-_6741430 1.660 ENSMUST00000100904.4
Gm3636
predicted gene 3636
chr2_-_168767029 1.637 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr9_+_119063429 1.633 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr7_-_29155597 1.590 ENSMUST00000123416.1
Fam98c
family with sequence similarity 98, member C
chr4_-_129227883 1.569 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr4_-_14621669 1.446 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr9_+_108339048 1.324 ENSMUST00000082429.5
Gpx1
glutathione peroxidase 1
chr3_-_67515487 1.320 ENSMUST00000178314.1
ENSMUST00000054825.4
Rarres1

retinoic acid receptor responder (tazarotene induced) 1

chr2_+_65845833 1.300 ENSMUST00000053910.3
Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_-_144270852 1.213 ENSMUST00000110030.3
Snx5
sorting nexin 5
chr3_+_55461758 1.128 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr7_+_38183217 1.125 ENSMUST00000165308.1
1600014C10Rik
RIKEN cDNA 1600014C10 gene
chrX_+_150589907 1.115 ENSMUST00000080884.4
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr9_+_123366921 1.101 ENSMUST00000038863.7
Lars2
leucyl-tRNA synthetase, mitochondrial
chr17_-_48432723 1.095 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr15_+_59315088 1.059 ENSMUST00000100640.4
Sqle
squalene epoxidase
chr16_+_58408443 1.042 ENSMUST00000046663.7
Dcbld2
discoidin, CUB and LCCL domain containing 2
chr13_-_53473074 1.019 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr2_+_125136692 1.001 ENSMUST00000099452.2
Ctxn2
cortexin 2
chr11_+_58171648 0.984 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr2_-_121235689 0.981 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr6_+_37870786 0.976 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr18_+_4920509 0.972 ENSMUST00000126977.1
Svil
supervillin
chr9_+_72806874 0.961 ENSMUST00000055535.8
Prtg
protogenin homolog (Gallus gallus)
chr2_+_65620829 0.960 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chrM_+_7005 0.945 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr17_-_15527281 0.941 ENSMUST00000154293.1
ENSMUST00000054450.6
Pdcd2

programmed cell death 2

chr5_+_135994796 0.933 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
Dtx2




deltex 2 homolog (Drosophila)




chr19_+_25406661 0.868 ENSMUST00000146647.1
Kank1
KN motif and ankyrin repeat domains 1
chr13_+_23533869 0.854 ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr10_-_61784014 0.829 ENSMUST00000020283.4
H2afy2
H2A histone family, member Y2
chr7_-_29155717 0.827 ENSMUST00000153251.1
Fam98c
family with sequence similarity 98, member C
chr9_-_112187766 0.802 ENSMUST00000111872.2
ENSMUST00000164754.2
Arpp21

cyclic AMP-regulated phosphoprotein, 21

chr5_-_136986829 0.795 ENSMUST00000034953.7
ENSMUST00000085941.5
Znhit1

zinc finger, HIT domain containing 1

chr2_+_69897220 0.793 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr13_+_90089705 0.763 ENSMUST00000012566.8
Tmem167
transmembrane protein 167
chr17_-_59013264 0.748 ENSMUST00000174122.1
ENSMUST00000025065.5
Nudt12

nudix (nucleoside diphosphate linked moiety X)-type motif 12

chr16_-_55283237 0.742 ENSMUST00000036412.3
Zpld1
zona pellucida like domain containing 1
chr1_-_135284075 0.707 ENSMUST00000077340.7
ENSMUST00000074357.7
Rnpep

arginyl aminopeptidase (aminopeptidase B)

chr15_+_59315030 0.707 ENSMUST00000022977.7
Sqle
squalene epoxidase
chr2_-_150255591 0.678 ENSMUST00000063463.5
Gm21994
predicted gene 21994
chr6_-_124779686 0.669 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23



leucine rich repeat containing 23



chr12_-_84617326 0.664 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr2_-_71367749 0.661 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr12_+_100110148 0.650 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr11_+_69838514 0.646 ENSMUST00000133967.1
ENSMUST00000094065.4
Tmem256

transmembrane protein 256

chr4_+_100478806 0.640 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chr18_-_56975333 0.638 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr8_+_107031218 0.588 ENSMUST00000034388.9
Vps4a
vacuolar protein sorting 4a (yeast)
chr9_-_55919605 0.584 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr14_-_20496780 0.575 ENSMUST00000022353.3
Mss51
MSS51 mitochondrial translational activator
chr1_-_172027269 0.562 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr12_+_52699297 0.557 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr3_-_10440054 0.554 ENSMUST00000099223.4
ENSMUST00000029047.6
Snx16

sorting nexin 16

chr5_+_138187485 0.550 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr2_+_119047129 0.539 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5

cancer susceptibility candidate 5

chr14_+_3224440 0.530 ENSMUST00000112797.4
D830030K20Rik
RIKEN cDNA D830030K20 gene
chr11_-_99230998 0.517 ENSMUST00000103133.3
Smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr2_-_132247747 0.513 ENSMUST00000110163.1
ENSMUST00000180286.1
ENSMUST00000028816.2
Tmem230


transmembrane protein 230


chr17_+_27839974 0.505 ENSMUST00000071006.7
Snrpc
U1 small nuclear ribonucleoprotein C
chr14_+_3846245 0.486 ENSMUST00000180934.1
Gm3033
predicted gene 3033
chr5_-_134946917 0.472 ENSMUST00000051401.2
Cldn4
claudin 4
chr13_+_67833235 0.458 ENSMUST00000060609.7
Gm10037
predicted gene 10037
chr10_+_128337761 0.446 ENSMUST00000005826.7
Cs
citrate synthase
chr15_-_36794498 0.443 ENSMUST00000110361.1
ENSMUST00000022894.7
ENSMUST00000110359.1
Ywhaz


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide


chr12_-_80643799 0.439 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr3_-_90389884 0.429 ENSMUST00000029541.5
Slc27a3
solute carrier family 27 (fatty acid transporter), member 3
chr3_+_122274371 0.427 ENSMUST00000035776.8
Dnttip2
deoxynucleotidyltransferase, terminal, interacting protein 2
chr2_-_69712461 0.423 ENSMUST00000102706.3
ENSMUST00000073152.6
Fastkd1

FAST kinase domains 1

chr9_-_62510498 0.420 ENSMUST00000164246.2
Coro2b
coronin, actin binding protein, 2B
chrM_+_8600 0.407 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chrM_+_2743 0.390 ENSMUST00000082392.1
mt-Nd1
mitochondrially encoded NADH dehydrogenase 1
chr12_+_10390756 0.386 ENSMUST00000020947.5
Rdh14
retinol dehydrogenase 14 (all-trans and 9-cis)
chr4_-_14621494 0.386 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr14_-_7450917 0.377 ENSMUST00000169555.1
Gm3755
predicted gene 3755
chr3_+_103575275 0.362 ENSMUST00000090697.4
Syt6
synaptotagmin VI
chr2_-_155074447 0.352 ENSMUST00000137242.1
ENSMUST00000054607.9
Ahcy

S-adenosylhomocysteine hydrolase

chr4_-_132075250 0.342 ENSMUST00000105970.1
ENSMUST00000105975.1
Epb4.1

erythrocyte protein band 4.1

chr17_-_55915870 0.341 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr7_+_128744870 0.339 ENSMUST00000042942.8
Sec23ip
Sec23 interacting protein
chrX_+_101429555 0.304 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein
chr7_+_12927410 0.303 ENSMUST00000045870.4
2310014L17Rik
RIKEN cDNA 2310014L17 gene
chr10_-_77166545 0.283 ENSMUST00000081654.6
Col18a1
collagen, type XVIII, alpha 1
chr3_+_103575231 0.282 ENSMUST00000121834.1
Syt6
synaptotagmin VI
chr7_+_57387304 0.281 ENSMUST00000085241.5
Gm9962
predicted gene 9962
chr13_-_66852017 0.272 ENSMUST00000059329.6
Gm17449
predicted gene, 17449
chr1_+_87183310 0.269 ENSMUST00000044533.8
Prss56
protease, serine 56
chr2_-_106002008 0.266 ENSMUST00000155811.1
Dnajc24
DnaJ (Hsp40) homolog, subfamily C, member 24
chr5_-_17888884 0.265 ENSMUST00000169095.1
Cd36
CD36 antigen
chr13_+_59585259 0.256 ENSMUST00000168367.1
ENSMUST00000022038.7
ENSMUST00000166923.1
Naa35


N(alpha)-acetyltransferase 35, NatC auxiliary subunit


chrX_-_143933204 0.247 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr5_-_137531952 0.246 ENSMUST00000140139.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr5_-_118244861 0.242 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chr9_-_71163224 0.237 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr18_+_59062282 0.217 ENSMUST00000165666.2
A730017C20Rik
RIKEN cDNA A730017C20 gene
chr8_-_54724317 0.217 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
Wdr17


WD repeat domain 17


chr9_-_99568849 0.209 ENSMUST00000035043.5
Armc8
armadillo repeat containing 8
chr12_-_55302974 0.204 ENSMUST00000021410.8
Ppp2r3c
protein phosphatase 2, regulatory subunit B'', gamma
chrX_-_160138375 0.198 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr7_+_126950687 0.183 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr2_+_174450678 0.180 ENSMUST00000016399.5
Tubb1
tubulin, beta 1 class VI
chrX_-_101086020 0.178 ENSMUST00000113710.1
Slc7a3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr13_-_92030897 0.176 ENSMUST00000149630.1
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr6_+_83165920 0.165 ENSMUST00000077407.5
ENSMUST00000113913.1
ENSMUST00000130212.1
Dctn1


dynactin 1


chr11_-_4095344 0.164 ENSMUST00000004868.5
Mtfp1
mitochondrial fission process 1
chr2_+_155751117 0.161 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr19_+_60811574 0.142 ENSMUST00000128357.1
ENSMUST00000119633.1
ENSMUST00000025957.8
Fam45a


family with sequence similarity 45, member A


chr9_+_40801235 0.138 ENSMUST00000117870.1
ENSMUST00000117557.1
Hspa8

heat shock protein 8

chr18_+_60212080 0.134 ENSMUST00000031549.5
Gm4951
predicted gene 4951
chr11_+_115564434 0.128 ENSMUST00000021085.4
Nup85
nucleoporin 85
chr10_+_23894688 0.127 ENSMUST00000041416.7
Vnn1
vanin 1
chr18_-_10706688 0.118 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3


abhydrolase domain containing 3


chr19_-_11604828 0.115 ENSMUST00000025582.4
Ms4a6d
membrane-spanning 4-domains, subfamily A, member 6D
chrM_+_14138 0.111 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr17_-_57031468 0.105 ENSMUST00000007814.8
Khsrp
KH-type splicing regulatory protein
chr2_-_125782834 0.090 ENSMUST00000053699.6
Secisbp2l
SECIS binding protein 2-like
chr10_-_88605017 0.087 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr18_+_59062462 0.079 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
A730017C20Rik



RIKEN cDNA A730017C20 gene



chr19_+_41933464 0.077 ENSMUST00000026154.7
Zdhhc16
zinc finger, DHHC domain containing 16
chr10_-_76110956 0.072 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr5_-_34660068 0.064 ENSMUST00000041364.9
Nop14
NOP14 nucleolar protein
chr8_-_84662841 0.045 ENSMUST00000060427.4
Ier2
immediate early response 2
chr5_-_137531204 0.029 ENSMUST00000150063.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr12_+_110601439 0.020 ENSMUST00000018851.7
Dync1h1
dynein cytoplasmic 1 heavy chain 1
chr18_-_24603791 0.014 ENSMUST00000070726.3
Slc39a6
solute carrier family 39 (metal ion transporter), member 6
chr5_+_29195983 0.009 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr14_+_118854695 0.006 ENSMUST00000100314.3
Cldn10
claudin 10

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.5 26.9 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.9 2.8 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.8 5.5 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.6 10.6 GO:0007530 sex determination(GO:0007530)
0.5 2.6 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.5 16.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.4 4.3 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.4 0.7 GO:0061738 late endosomal microautophagy(GO:0061738)
0.3 3.1 GO:0016198 axon choice point recognition(GO:0016198)
0.3 1.0 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.3 0.9 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3 5.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.3 1.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.2 1.0 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 5.0 GO:0007614 short-term memory(GO:0007614)
0.2 4.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 0.6 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.2 0.6 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.7 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.2 0.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 1.1 GO:0019532 oxalate transport(GO:0019532)
0.2 2.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 3.6 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.8 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 3.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.9 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.8 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 3.7 GO:0035329 hippo signaling(GO:0035329)
0.1 3.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.3 GO:2000334 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 2.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 2.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.1 GO:0080111 DNA demethylation(GO:0080111)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.7 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.3 GO:0046689 response to mercury ion(GO:0046689)
0.1 0.5 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.5 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 3.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.2 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:0015819 lysine transport(GO:0015819)
0.0 0.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 2.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 10.4 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.4 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.4 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 2.9 GO:0000910 cytokinesis(GO:0000910)
0.0 0.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:0051693 actin filament capping(GO:0051693)
0.0 0.4 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 1.7 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.2 GO:0051900 regulation of mitochondrial depolarization(GO:0051900)
0.0 2.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.7 GO:0022900 electron transport chain(GO:0022900)
0.0 0.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.6 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) dendritic spine neck(GO:0044326)
0.4 1.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.3 1.3 GO:0097413 Lewy body(GO:0097413)
0.3 2.6 GO:0098536 deuterosome(GO:0098536)
0.3 1.8 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 2.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 2.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 1.0 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 3.1 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.6 GO:0060187 cell pole(GO:0060187)
0.1 0.8 GO:0001740 Barr body(GO:0001740)
0.1 2.3 GO:0002102 podosome(GO:0002102)
0.1 0.6 GO:0033503 HULC complex(GO:0033503)
0.1 4.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 0.6 GO:0090543 Flemming body(GO:0090543)
0.1 2.8 GO:0043034 costamere(GO:0043034)
0.1 0.8 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.4 GO:0034709 methylosome(GO:0034709)
0.1 5.0 GO:0043195 terminal bouton(GO:0043195)
0.1 0.5 GO:0000243 commitment complex(GO:0000243)
0.1 17.7 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 1.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 4.1 GO:0000792 heterochromatin(GO:0000792)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 4.2 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.2 GO:0070382 exocytic vesicle(GO:0070382)
0.0 1.0 GO:0005657 replication fork(GO:0005657)
0.0 0.1 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0030689 preribosome, small subunit precursor(GO:0030688) Noc complex(GO:0030689)
0.0 0.9 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.8 GO:0070469 respiratory chain(GO:0070469)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.5 4.3 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)
0.5 3.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.4 1.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.3 10.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.2 1.2 GO:0034452 dynactin binding(GO:0034452)
0.2 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 1.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 1.0 GO:0034056 estrogen response element binding(GO:0034056)
0.1 27.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 5.5 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 2.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.8 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.6 GO:0043495 protein anchor(GO:0043495)
0.1 2.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 4.8 GO:0019842 vitamin binding(GO:0019842)
0.1 0.7 GO:0050897 cobalt ion binding(GO:0050897)
0.1 1.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 9.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.7 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.4 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) very long-chain fatty acid-CoA ligase activity(GO:0031957) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0 2.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 1.0 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.9 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 1.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.4 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 3.5 GO:0003924 GTPase activity(GO:0003924)
0.0 11.6 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0008198 ATPase activator activity(GO:0001671) ferrous iron binding(GO:0008198)
0.0 0.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 4.1 GO:0003779 actin binding(GO:0003779)
0.0 7.8 GO:0043565 sequence-specific DNA binding(GO:0043565)