Motif ID: Irf2_Irf1_Irf8_Irf9_Irf7
Z-value: 3.769
Transcription factors associated with Irf2_Irf1_Irf8_Irf9_Irf7:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Irf1 | ENSMUSG00000018899.10 | Irf1 |
| Irf2 | ENSMUSG00000031627.7 | Irf2 |
| Irf7 | ENSMUSG00000025498.8 | Irf7 |
| Irf8 | ENSMUSG00000041515.3 | Irf8 |
| Irf9 | ENSMUSG00000002325.8 | Irf9 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Irf1 | mm10_v2_chr11_+_53770458_53770509 | 0.69 | 2.8e-04 | Click! |
| Irf8 | mm10_v2_chr8_+_120736352_120736385 | 0.49 | 1.8e-02 | Click! |
| Irf2 | mm10_v2_chr8_+_46739745_46739791 | 0.47 | 2.3e-02 | Click! |
| Irf7 | mm10_v2_chr7_-_141266415_141266481 | 0.37 | 8.2e-02 | Click! |
| Irf9 | mm10_v2_chr14_+_55604550_55604579 | -0.01 | 9.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 12.2 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 3.8 | 11.4 | GO:0032687 | negative regulation of interferon-alpha production(GO:0032687) |
| 3.6 | 10.8 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 2.6 | 10.5 | GO:0009597 | detection of virus(GO:0009597) |
| 2.0 | 14.3 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
| 1.9 | 7.5 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 1.8 | 24.9 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 1.4 | 4.2 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
| 1.4 | 13.6 | GO:2000051 | negative regulation of non-canonical Wnt signaling pathway(GO:2000051) |
| 1.3 | 6.7 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 1.2 | 44.9 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 1.2 | 3.5 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 1.1 | 3.2 | GO:0097309 | cap1 mRNA methylation(GO:0097309) |
| 1.0 | 7.0 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 1.0 | 4.0 | GO:0042228 | interleukin-8 biosynthetic process(GO:0042228) |
| 1.0 | 2.9 | GO:0043696 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
| 0.9 | 26.3 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.8 | 2.5 | GO:0042196 | dichloromethane metabolic process(GO:0018900) chlorinated hydrocarbon metabolic process(GO:0042196) halogenated hydrocarbon metabolic process(GO:0042197) |
| 0.8 | 4.0 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.8 | 24.1 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.8 | 0.8 | GO:2000564 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
| 0.8 | 2.3 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.7 | 8.5 | GO:0019885 | antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885) |
| 0.7 | 1.3 | GO:1900020 | Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020) |
| 0.6 | 5.0 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.6 | 4.4 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.6 | 3.1 | GO:0070460 | thyroid-stimulating hormone secretion(GO:0070460) |
| 0.6 | 1.8 | GO:0019441 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
| 0.6 | 1.8 | GO:0006553 | lysine metabolic process(GO:0006553) |
| 0.5 | 1.1 | GO:0072223 | metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) |
| 0.5 | 3.0 | GO:1903056 | regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056) |
| 0.5 | 1.0 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.4 | 1.3 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.4 | 1.7 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.4 | 1.7 | GO:0003430 | tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430) |
| 0.4 | 0.8 | GO:0050713 | negative regulation of interleukin-1 beta secretion(GO:0050713) |
| 0.4 | 1.1 | GO:0033860 | regulation of NAD(P)H oxidase activity(GO:0033860) |
| 0.4 | 0.7 | GO:0070384 | Harderian gland development(GO:0070384) |
| 0.3 | 1.7 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.3 | 0.3 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.3 | 1.6 | GO:0051611 | negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 0.3 | 2.0 | GO:0048549 | positive regulation of pinocytosis(GO:0048549) |
| 0.3 | 1.6 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.3 | 2.3 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.3 | 2.5 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.3 | 1.2 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 0.3 | 12.6 | GO:0046825 | regulation of protein export from nucleus(GO:0046825) |
| 0.3 | 0.8 | GO:0014891 | striated muscle atrophy(GO:0014891) |
| 0.3 | 1.4 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.3 | 0.8 | GO:0019883 | antigen processing and presentation of endogenous antigen(GO:0019883) |
| 0.3 | 1.1 | GO:0032621 | interleukin-18 production(GO:0032621) |
| 0.2 | 2.7 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.2 | 0.2 | GO:1903463 | regulation of mitotic cell cycle DNA replication(GO:1903463) |
| 0.2 | 1.2 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
| 0.2 | 0.7 | GO:0051342 | regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344) |
| 0.2 | 0.9 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
| 0.2 | 3.1 | GO:0032620 | interleukin-17 production(GO:0032620) |
| 0.2 | 1.3 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
| 0.2 | 1.1 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.2 | 1.1 | GO:0035989 | tendon development(GO:0035989) |
| 0.2 | 0.2 | GO:0018307 | enzyme active site formation(GO:0018307) |
| 0.2 | 2.5 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.2 | 2.5 | GO:0009072 | aromatic amino acid family metabolic process(GO:0009072) |
| 0.2 | 0.8 | GO:0010940 | positive regulation of necrotic cell death(GO:0010940) |
| 0.2 | 2.1 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.2 | 0.6 | GO:0006533 | aspartate catabolic process(GO:0006533) |
| 0.2 | 1.0 | GO:0042701 | progesterone secretion(GO:0042701) |
| 0.2 | 1.6 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.2 | 3.0 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.2 | 0.6 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.2 | 2.6 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.2 | 0.5 | GO:0043651 | linoleic acid metabolic process(GO:0043651) |
| 0.2 | 0.5 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.2 | 0.7 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.2 | 1.2 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.2 | 1.0 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.2 | 1.3 | GO:0071360 | cellular response to exogenous dsRNA(GO:0071360) |
| 0.2 | 0.5 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.2 | 0.6 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 0.2 | 0.3 | GO:0070944 | neutrophil mediated killing of bacterium(GO:0070944) |
| 0.2 | 0.3 | GO:0001866 | NK T cell proliferation(GO:0001866) |
| 0.2 | 2.0 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
| 0.1 | 1.2 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.1 | 1.5 | GO:1903608 | protein localization to cytoplasmic stress granule(GO:1903608) |
| 0.1 | 0.4 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
| 0.1 | 0.6 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.1 | 0.7 | GO:0090292 | nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.1 | 0.6 | GO:0071449 | cellular response to lipid hydroperoxide(GO:0071449) |
| 0.1 | 1.9 | GO:0010447 | response to acidic pH(GO:0010447) |
| 0.1 | 0.8 | GO:0034308 | primary alcohol metabolic process(GO:0034308) |
| 0.1 | 1.7 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 0.4 | GO:0097343 | ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026) |
| 0.1 | 0.8 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.1 | 1.0 | GO:0019348 | polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348) |
| 0.1 | 0.4 | GO:1990481 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481) |
| 0.1 | 0.6 | GO:0045213 | neurotransmitter receptor metabolic process(GO:0045213) |
| 0.1 | 0.7 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.1 | 0.9 | GO:0002347 | response to tumor cell(GO:0002347) |
| 0.1 | 0.8 | GO:0031293 | membrane protein intracellular domain proteolysis(GO:0031293) |
| 0.1 | 12.9 | GO:0016579 | protein deubiquitination(GO:0016579) |
| 0.1 | 0.3 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.1 | 0.7 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.1 | 0.2 | GO:0006624 | vacuolar protein processing(GO:0006624) |
| 0.1 | 0.4 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.1 | 0.9 | GO:0032836 | glomerular basement membrane development(GO:0032836) |
| 0.1 | 1.0 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.1 | 0.3 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.1 | 0.3 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
| 0.1 | 0.5 | GO:0036337 | Fas signaling pathway(GO:0036337) |
| 0.1 | 0.9 | GO:0007379 | segment specification(GO:0007379) |
| 0.1 | 0.3 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.1 | 0.3 | GO:0021852 | pyramidal neuron migration(GO:0021852) |
| 0.1 | 0.4 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
| 0.1 | 0.6 | GO:1903301 | positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301) |
| 0.1 | 0.4 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
| 0.1 | 0.9 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.1 | 0.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.1 | 0.5 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.1 | 0.4 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.1 | 0.1 | GO:0046533 | regulation of photoreceptor cell differentiation(GO:0046532) negative regulation of photoreceptor cell differentiation(GO:0046533) |
| 0.1 | 0.4 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.1 | 0.7 | GO:0060613 | fat pad development(GO:0060613) |
| 0.1 | 0.8 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.1 | 0.6 | GO:0045651 | positive regulation of macrophage differentiation(GO:0045651) |
| 0.1 | 0.9 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.1 | GO:1903393 | positive regulation of adherens junction organization(GO:1903393) |
| 0.1 | 0.2 | GO:2001245 | regulation of phosphatidylcholine biosynthetic process(GO:2001245) |
| 0.1 | 0.2 | GO:0090272 | negative regulation of fibroblast growth factor production(GO:0090272) |
| 0.1 | 1.6 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 0.7 | GO:0072010 | renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
| 0.1 | 0.3 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.1 | 0.8 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.1 | 0.4 | GO:1903352 | ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352) |
| 0.1 | 0.5 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.1 | 0.5 | GO:0061684 | chaperone-mediated autophagy(GO:0061684) |
| 0.1 | 0.3 | GO:0090310 | negative regulation of methylation-dependent chromatin silencing(GO:0090310) |
| 0.1 | 0.4 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
| 0.1 | 1.4 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
| 0.1 | 0.5 | GO:0072602 | interleukin-4 secretion(GO:0072602) |
| 0.1 | 1.4 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.1 | 1.3 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.1 | 0.2 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994) |
| 0.1 | 0.4 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.1 | 2.5 | GO:0010390 | histone monoubiquitination(GO:0010390) |
| 0.1 | 0.5 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 0.1 | 1.4 | GO:0006379 | mRNA cleavage(GO:0006379) |
| 0.1 | 0.3 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 0.1 | 0.7 | GO:0061462 | protein localization to lysosome(GO:0061462) |
| 0.1 | 2.8 | GO:0042632 | cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092) |
| 0.1 | 2.0 | GO:0002053 | positive regulation of mesenchymal cell proliferation(GO:0002053) |
| 0.1 | 0.3 | GO:0044539 | long-chain fatty acid import(GO:0044539) |
| 0.1 | 0.4 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.1 | 1.6 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
| 0.0 | 0.5 | GO:0071044 | histone mRNA catabolic process(GO:0071044) |
| 0.0 | 0.3 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.0 | 0.3 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.0 | 0.3 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 0.1 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
| 0.0 | 0.1 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
| 0.0 | 1.9 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.2 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 0.0 | 0.4 | GO:0009992 | cellular water homeostasis(GO:0009992) |
| 0.0 | 0.7 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.0 | 0.2 | GO:0090168 | intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) Golgi reassembly(GO:0090168) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) |
| 0.0 | 1.6 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.0 | 0.2 | GO:1902965 | regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966) |
| 0.0 | 0.3 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.0 | 1.2 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.0 | 1.3 | GO:0001919 | regulation of receptor recycling(GO:0001919) |
| 0.0 | 0.1 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.0 | 0.3 | GO:2000650 | negative regulation of sodium ion transmembrane transporter activity(GO:2000650) |
| 0.0 | 0.1 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.0 | 0.8 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
| 0.0 | 0.2 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.0 | 0.3 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.0 | 3.8 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.3 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.0 | 0.4 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.0 | 0.3 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
| 0.0 | 0.5 | GO:0050434 | positive regulation of viral transcription(GO:0050434) |
| 0.0 | 0.2 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.0 | 0.1 | GO:0043974 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) negative regulation of histone H3-K27 acetylation(GO:1901675) |
| 0.0 | 0.8 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.0 | 0.5 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 0.3 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.2 | GO:1903887 | motile primary cilium assembly(GO:1903887) |
| 0.0 | 3.4 | GO:0016052 | carbohydrate catabolic process(GO:0016052) |
| 0.0 | 0.4 | GO:0001963 | synaptic transmission, dopaminergic(GO:0001963) |
| 0.0 | 0.2 | GO:0001867 | complement activation, lectin pathway(GO:0001867) |
| 0.0 | 0.1 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.0 | 0.3 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.0 | 0.4 | GO:1901522 | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522) |
| 0.0 | 0.1 | GO:1902669 | positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669) |
| 0.0 | 1.5 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.1 | GO:0097105 | presynaptic membrane assembly(GO:0097105) |
| 0.0 | 1.0 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.0 | 0.1 | GO:0014832 | urinary bladder smooth muscle contraction(GO:0014832) |
| 0.0 | 0.5 | GO:0046856 | phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 1.1 | GO:0008542 | visual learning(GO:0008542) |
| 0.0 | 0.2 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
| 0.0 | 0.3 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.0 | 0.3 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.0 | 0.3 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 9.0 | GO:0006914 | autophagy(GO:0006914) |
| 0.0 | 1.1 | GO:0030279 | negative regulation of ossification(GO:0030279) |
| 0.0 | 0.5 | GO:0007143 | female meiotic division(GO:0007143) |
| 0.0 | 0.3 | GO:0036065 | fucosylation(GO:0036065) |
| 0.0 | 0.1 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.0 | 0.5 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.1 | GO:0000491 | small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492) |
| 0.0 | 0.2 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 0.0 | 0.3 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.1 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.0 | 0.0 | GO:1900127 | positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 0.0 | 1.6 | GO:0046488 | phosphatidylinositol metabolic process(GO:0046488) |
| 0.0 | 0.4 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.0 | 0.2 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.0 | 1.5 | GO:0048814 | regulation of dendrite morphogenesis(GO:0048814) |
| 0.0 | 0.6 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.0 | 1.1 | GO:0043473 | pigmentation(GO:0043473) |
| 0.0 | 0.6 | GO:0007032 | endosome organization(GO:0007032) |
| 0.0 | 0.2 | GO:0009143 | nucleoside triphosphate catabolic process(GO:0009143) |
| 0.0 | 1.0 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 0.1 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.0 | 0.4 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
| 0.0 | 1.6 | GO:0008654 | phospholipid biosynthetic process(GO:0008654) |
| 0.0 | 0.2 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
| 0.0 | 0.2 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.0 | 0.1 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.0 | 0.4 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662) |
| 0.0 | 0.1 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.0 | 0.1 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.0 | 0.1 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.0 | 0.1 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.0 | 0.1 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.0 | 0.2 | GO:0045943 | positive regulation of transcription from RNA polymerase I promoter(GO:0045943) |
| 0.0 | 0.1 | GO:0036265 | RNA (guanine-N7)-methylation(GO:0036265) |
| 0.0 | 0.2 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.2 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.0 | GO:0008300 | isoprenoid catabolic process(GO:0008300) |
| 0.0 | 0.3 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.0 | 0.5 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.1 | GO:0090140 | regulation of mitochondrial fission(GO:0090140) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.6 | 10.7 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 1.4 | 18.1 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 1.3 | 3.8 | GO:0042025 | viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 0.7 | 2.1 | GO:0097447 | dendritic tree(GO:0097447) |
| 0.6 | 5.0 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.5 | 7.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.5 | 3.2 | GO:0042825 | TAP complex(GO:0042825) |
| 0.4 | 1.3 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.4 | 1.2 | GO:0072534 | perineuronal net(GO:0072534) |
| 0.4 | 1.5 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.4 | 1.5 | GO:0097165 | nuclear stress granule(GO:0097165) |
| 0.3 | 14.2 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.3 | 1.5 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.3 | 2.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.3 | 0.8 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.3 | 0.5 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.3 | 1.0 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.2 | 0.7 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.2 | 1.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.2 | 0.9 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.2 | 1.1 | GO:1990462 | omegasome(GO:1990462) |
| 0.2 | 0.8 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.2 | 1.4 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.2 | 0.6 | GO:0030690 | Noc1p-Noc2p complex(GO:0030690) |
| 0.2 | 0.9 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.2 | 3.5 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.2 | 7.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.2 | 0.8 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.1 | 0.8 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.1 | 1.7 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.1 | 0.9 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 0.7 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.1 | 10.6 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.1 | 1.1 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.1 | 11.0 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 0.7 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.1 | 17.3 | GO:0005770 | late endosome(GO:0005770) |
| 0.1 | 2.3 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.1 | 0.5 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 0.4 | GO:0090661 | box H/ACA telomerase RNP complex(GO:0090661) |
| 0.1 | 0.7 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.1 | 0.3 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 0.3 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.1 | 0.2 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.1 | 1.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 1.0 | GO:0071203 | WASH complex(GO:0071203) |
| 0.1 | 0.7 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 0.7 | GO:0033179 | proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.1 | 0.4 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 0.2 | GO:0016939 | kinesin II complex(GO:0016939) |
| 0.1 | 0.8 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.1 | 0.8 | GO:0005675 | holo TFIIH complex(GO:0005675) |
| 0.1 | 0.6 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 2.0 | GO:0044298 | cell body membrane(GO:0044298) |
| 0.1 | 1.8 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 0.8 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 0.6 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 1.7 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 1.7 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 0.1 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.0 | 0.2 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.6 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.0 | 0.6 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.7 | GO:0043657 | host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657) |
| 0.0 | 0.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.3 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 0.1 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.3 | GO:0033503 | HULC complex(GO:0033503) |
| 0.0 | 0.1 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 0.3 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.0 | 1.3 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 1.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.5 | GO:0031010 | ISWI-type complex(GO:0031010) |
| 0.0 | 0.2 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 0.1 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.0 | 0.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 0.1 | GO:0042611 | MHC protein complex(GO:0042611) |
| 0.0 | 6.0 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.3 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 0.8 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 1.3 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.3 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.0 | 7.7 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 0.1 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 1.0 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 2.3 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.2 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.1 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.0 | 0.2 | GO:0031414 | N-terminal protein acetyltransferase complex(GO:0031414) |
| 0.0 | 0.2 | GO:0051286 | cell tip(GO:0051286) |
| 0.0 | 0.6 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 13.6 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 0.3 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 2.2 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 0.5 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.0 | 210.6 | GO:0005575 | cellular_component(GO:0005575) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 10.3 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 1.3 | 3.8 | GO:0070052 | collagen V binding(GO:0070052) |
| 1.3 | 12.6 | GO:0016920 | pyroglutamyl-peptidase activity(GO:0016920) |
| 1.2 | 4.7 | GO:0047844 | deoxycytidine deaminase activity(GO:0047844) |
| 1.0 | 4.0 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 1.0 | 4.0 | GO:0050700 | CARD domain binding(GO:0050700) |
| 1.0 | 12.4 | GO:0016443 | bidentate ribonuclease III activity(GO:0016443) |
| 0.9 | 17.9 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.8 | 2.5 | GO:0019120 | hydrolase activity, acting on acid halide bonds(GO:0016824) hydrolase activity, acting on acid halide bonds, in C-halide compounds(GO:0019120) alkylhalidase activity(GO:0047651) |
| 0.8 | 3.2 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.8 | 3.8 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.7 | 3.0 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.7 | 10.5 | GO:0046977 | TAP binding(GO:0046977) |
| 0.7 | 2.0 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.6 | 14.2 | GO:0005521 | lamin binding(GO:0005521) |
| 0.6 | 1.8 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.6 | 3.0 | GO:0005030 | neurotrophin receptor activity(GO:0005030) |
| 0.5 | 6.5 | GO:0031386 | protein tag(GO:0031386) |
| 0.5 | 1.5 | GO:0004510 | tryptophan 5-monooxygenase activity(GO:0004510) |
| 0.5 | 1.4 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.5 | 4.3 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.5 | 3.2 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.5 | 1.8 | GO:0016647 | oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647) |
| 0.4 | 1.3 | GO:0005110 | frizzled-2 binding(GO:0005110) |
| 0.4 | 0.4 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.4 | 1.7 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 0.4 | 2.1 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.4 | 1.6 | GO:0005008 | hepatocyte growth factor-activated receptor activity(GO:0005008) |
| 0.4 | 1.6 | GO:0086038 | calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038) |
| 0.4 | 1.9 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.4 | 1.1 | GO:0001716 | L-amino-acid oxidase activity(GO:0001716) |
| 0.3 | 2.3 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.3 | 3.8 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.3 | 45.0 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.3 | 1.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.3 | 20.2 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.2 | 0.7 | GO:0036004 | GAF domain binding(GO:0036004) |
| 0.2 | 1.4 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.2 | 3.6 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 0.7 | GO:0004471 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) |
| 0.2 | 3.5 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.2 | 2.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 5.0 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.2 | 1.1 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 0.2 | 1.0 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.2 | 1.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.2 | 1.5 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.2 | 2.1 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.2 | 0.5 | GO:0052658 | inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) |
| 0.2 | 0.7 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.2 | 0.5 | GO:0005171 | hepatocyte growth factor receptor binding(GO:0005171) |
| 0.2 | 0.6 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.2 | 0.8 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.2 | 2.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.2 | 0.6 | GO:0003884 | D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922) |
| 0.2 | 0.6 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.1 | 0.6 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.1 | 0.4 | GO:0072345 | NAADP-sensitive calcium-release channel activity(GO:0072345) |
| 0.1 | 0.6 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.1 | 0.8 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 4.8 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 12.8 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.1 | 1.2 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.1 | 0.4 | GO:0005118 | sevenless binding(GO:0005118) |
| 0.1 | 0.8 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 1.2 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.1 | 0.5 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.1 | 0.4 | GO:0043559 | insulin binding(GO:0043559) |
| 0.1 | 0.5 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 0.1 | 1.1 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.1 | 0.5 | GO:0070330 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) aromatase activity(GO:0070330) |
| 0.1 | 0.7 | GO:0042608 | T cell receptor binding(GO:0042608) |
| 0.1 | 0.3 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
| 0.1 | 0.5 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.1 | 0.2 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.1 | 2.3 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 1.4 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
| 0.1 | 1.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 1.4 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 1.2 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.1 | 0.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.1 | 0.9 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 6.7 | GO:0046332 | SMAD binding(GO:0046332) |
| 0.1 | 0.7 | GO:0018741 | alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902) |
| 0.1 | 0.8 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.1 | 1.7 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.1 | 1.7 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.1 | 2.0 | GO:0043236 | laminin binding(GO:0043236) |
| 0.1 | 1.8 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.3 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.4 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.1 | 0.1 | GO:0034211 | GTP-dependent protein kinase activity(GO:0034211) |
| 0.1 | 5.5 | GO:0016836 | hydro-lyase activity(GO:0016836) |
| 0.1 | 0.7 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.1 | 0.6 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.1 | 0.3 | GO:0003844 | 1,4-alpha-glucan branching enzyme activity(GO:0003844) |
| 0.1 | 0.6 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.1 | 0.8 | GO:0016208 | AMP binding(GO:0016208) |
| 0.1 | 0.5 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.1 | 1.3 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.1 | 0.4 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
| 0.1 | 0.2 | GO:0008475 | procollagen-lysine 5-dioxygenase activity(GO:0008475) |
| 0.1 | 0.3 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.1 | 0.6 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 0.3 | GO:0043842 | Kdo transferase activity(GO:0043842) |
| 0.1 | 1.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.7 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.1 | GO:0098821 | BMP receptor activity(GO:0098821) |
| 0.1 | 0.3 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.1 | 0.3 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
| 0.0 | 1.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.8 | GO:0005123 | death receptor binding(GO:0005123) |
| 0.0 | 0.8 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.0 | 0.3 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 2.0 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.1 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.2 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.0 | 0.2 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
| 0.0 | 0.3 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.0 | 14.7 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 0.4 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.0 | 0.1 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
| 0.0 | 1.3 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.8 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.5 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
| 0.0 | 0.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.0 | 1.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.6 | GO:0001848 | complement binding(GO:0001848) |
| 0.0 | 0.3 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.1 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.0 | 0.4 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.0 | 0.3 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.0 | 0.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.6 | GO:0004602 | glutathione peroxidase activity(GO:0004602) |
| 0.0 | 0.1 | GO:0008176 | tRNA (guanine-N7-)-methyltransferase activity(GO:0008176) |
| 0.0 | 0.2 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.0 | 0.4 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 1.4 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.0 | 0.2 | GO:0030346 | protein phosphatase 2B binding(GO:0030346) |
| 0.0 | 0.1 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 7.8 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
| 0.0 | 0.1 | GO:0048039 | oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635) ubiquinone binding(GO:0048039) |
| 0.0 | 0.2 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.6 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.4 | GO:0019840 | isoprenoid binding(GO:0019840) |
| 0.0 | 0.2 | GO:0015168 | structural constituent of eye lens(GO:0005212) glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254) |
| 0.0 | 8.5 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.5 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
| 0.0 | 0.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 1.6 | GO:0005496 | steroid binding(GO:0005496) |
| 0.0 | 0.4 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.0 | 0.4 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 2.1 | GO:0001948 | glycoprotein binding(GO:0001948) |
| 0.0 | 0.5 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.1 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.0 | 0.2 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 1.9 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 0.1 | GO:0038024 | cargo receptor activity(GO:0038024) |
| 0.0 | 0.4 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.0 | 0.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 0.5 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.3 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.0 | 0.5 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.1 | GO:0001609 | G-protein coupled adenosine receptor activity(GO:0001609) |
| 0.0 | 0.2 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
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