Motif ID: Osr2_Osr1
Z-value: 0.800
Transcription factors associated with Osr2_Osr1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Osr1 | ENSMUSG00000048387.7 | Osr1 |
Osr2 | ENSMUSG00000022330.4 | Osr2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Osr1 | mm10_v2_chr12_+_9574437_9574448 | -0.24 | 2.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0070172 | oculomotor nerve development(GO:0021557) positive regulation of tooth mineralization(GO:0070172) |
0.5 | 1.9 | GO:0033499 | galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623) |
0.4 | 1.7 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.4 | 2.5 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.3 | 9.0 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
0.2 | 0.7 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
0.2 | 0.9 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.2 | 0.6 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
0.2 | 0.6 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) glutamate secretion, neurotransmission(GO:0061535) |
0.2 | 2.8 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069) |
0.1 | 0.6 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
0.1 | 0.4 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
0.1 | 0.6 | GO:1904565 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
0.1 | 0.7 | GO:0036324 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
0.1 | 0.5 | GO:0006547 | histidine metabolic process(GO:0006547) |
0.1 | 0.5 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
0.1 | 0.3 | GO:0033860 | regulation of NAD(P)H oxidase activity(GO:0033860) flavin-containing compound metabolic process(GO:0042726) |
0.1 | 0.5 | GO:0048631 | regulation of skeletal muscle tissue growth(GO:0048631) |
0.1 | 0.3 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.1 | 0.1 | GO:1901419 | regulation of response to alcohol(GO:1901419) |
0.1 | 1.7 | GO:1900452 | regulation of long term synaptic depression(GO:1900452) |
0.1 | 0.6 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.1 | 0.4 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.1 | 0.6 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
0.1 | 0.6 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
0.0 | 0.3 | GO:0048254 | snoRNA localization(GO:0048254) |
0.0 | 0.5 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
0.0 | 0.4 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) protein K6-linked ubiquitination(GO:0085020) |
0.0 | 0.3 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.0 | 0.1 | GO:0070844 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
0.0 | 2.3 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
0.0 | 1.1 | GO:0046677 | response to antibiotic(GO:0046677) |
0.0 | 0.9 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 0.5 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.7 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.0 | 0.6 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.0 | 1.4 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
0.0 | 0.1 | GO:0030576 | Cajal body organization(GO:0030576) |
0.0 | 0.3 | GO:0045351 | type I interferon biosynthetic process(GO:0045351) |
0.0 | 0.3 | GO:1903894 | regulation of IRE1-mediated unfolded protein response(GO:1903894) |
0.0 | 0.4 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.0 | 3.0 | GO:0007605 | sensory perception of sound(GO:0007605) |
0.0 | 0.8 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
0.0 | 0.1 | GO:0021914 | negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914) |
0.0 | 0.4 | GO:0043486 | histone exchange(GO:0043486) |
0.0 | 0.1 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.0 | 0.3 | GO:0019430 | removal of superoxide radicals(GO:0019430) |
0.0 | 0.3 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 1.1 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 0.2 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
0.0 | 0.4 | GO:0035456 | response to interferon-beta(GO:0035456) |
0.0 | 0.5 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.7 | GO:1990032 | parallel fiber(GO:1990032) |
0.1 | 0.3 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.1 | 0.5 | GO:0008623 | CHRAC(GO:0008623) |
0.1 | 8.9 | GO:0005905 | clathrin-coated pit(GO:0005905) |
0.1 | 0.6 | GO:0071437 | invadopodium(GO:0071437) |
0.1 | 0.5 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.1 | 2.8 | GO:0032420 | stereocilium(GO:0032420) ciliary membrane(GO:0060170) |
0.1 | 0.6 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.1 | 0.5 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
0.1 | 0.5 | GO:0061617 | MICOS complex(GO:0061617) |
0.0 | 0.9 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.0 | 0.4 | GO:0070531 | BRCA1-A complex(GO:0070531) |
0.0 | 0.6 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 3.2 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.3 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
0.0 | 0.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
0.0 | 0.3 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.0 | 0.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.2 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
0.0 | 0.6 | GO:0043034 | costamere(GO:0043034) |
0.0 | 0.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.4 | GO:0000795 | synaptonemal complex(GO:0000795) |
0.0 | 1.9 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
0.0 | 0.2 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.2 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.0 | 9.0 | GO:0016494 | C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958) |
0.4 | 2.8 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.3 | 0.9 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.3 | 1.7 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
0.2 | 0.7 | GO:0042284 | sphingolipid delta-4 desaturase activity(GO:0042284) |
0.2 | 0.6 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379) |
0.2 | 0.6 | GO:0004816 | asparagine-tRNA ligase activity(GO:0004816) |
0.1 | 1.0 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
0.1 | 0.5 | GO:0034056 | estrogen response element binding(GO:0034056) |
0.1 | 1.9 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.1 | 0.7 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
0.1 | 0.6 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
0.1 | 0.2 | GO:0098634 | protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639) |
0.0 | 0.3 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.0 | 1.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 0.3 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.0 | 0.8 | GO:0050811 | GABA receptor binding(GO:0050811) |
0.0 | 0.3 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.0 | 0.8 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
0.0 | 0.1 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
0.0 | 0.6 | GO:0034946 | 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466) |
0.0 | 0.6 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 1.4 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
0.0 | 1.2 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.2 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.3 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.6 | GO:0017025 | TBP-class protein binding(GO:0017025) |
0.0 | 0.1 | GO:0003945 | N-acetyllactosamine synthase activity(GO:0003945) |
0.0 | 3.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.6 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
0.0 | 0.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.9 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
0.0 | 0.4 | GO:0005272 | sodium channel activity(GO:0005272) |
0.0 | 0.5 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.5 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) |
0.0 | 0.1 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
0.0 | 0.2 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |