Motif ID: Osr2_Osr1

Z-value: 0.800

Transcription factors associated with Osr2_Osr1:

Gene SymbolEntrez IDGene Name
Osr1 ENSMUSG00000048387.7 Osr1
Osr2 ENSMUSG00000022330.4 Osr2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Osr1mm10_v2_chr12_+_9574437_9574448-0.242.8e-01Click!


Activity profile for motif Osr2_Osr1.

activity profile for motif Osr2_Osr1


Sorted Z-values histogram for motif Osr2_Osr1

Sorted Z-values for motif Osr2_Osr1



Network of associatons between targets according to the STRING database.



First level regulatory network of Osr2_Osr1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 164 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_90203980 9.027 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr4_+_13743424 2.897 ENSMUST00000006761.3
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_80128834 2.786 ENSMUST00000102654.4
ENSMUST00000102655.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr19_+_48206025 1.724 ENSMUST00000078880.5
 Sorcs3
sortilin-related VPS10 domain containing receptor 3
chr19_+_20601958 1.671 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr13_-_40733768 1.560 ENSMUST00000110193.2
 Tfap2a
transcription factor AP-2, alpha
chr10_+_77829467 1.553 ENSMUST00000092368.2
 Tspear
thrombospondin type laminin G domain and EAR repeats
chr11_-_100759942 1.466 ENSMUST00000107363.2
 Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr3_-_89322883 1.377 ENSMUST00000029673.5
 Efna3
ephrin A3
chr11_-_100759740 1.242 ENSMUST00000107361.2
 Kcnh4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr10_+_77864623 1.226 ENSMUST00000092366.2
 Tspear
thrombospondin type laminin G domain and EAR repeats
chr4_-_134254076 1.153 ENSMUST00000060050.5
 Grrp1
glycine/arginine rich protein 1
chr15_+_84232030 1.056 ENSMUST00000023072.6
 Parvb
parvin, beta
chr2_+_164562579 1.048 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
 Wfdc2


WAP four-disulfide core domain 2


chr4_+_135963742 1.027 ENSMUST00000149636.1
ENSMUST00000143304.1
 Gale

galactose-4-epimerase, UDP

chr4_+_3940747 1.004 ENSMUST00000119403.1
 Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr9_+_87022014 0.998 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
 Cyb5r4


cytochrome b5 reductase 4


chr10_+_3740348 0.996 ENSMUST00000120274.1
 Plekhg1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr2_+_136892168 0.931 ENSMUST00000099311.2
 Slx4ip
SLX4 interacting protein
chr9_-_16378231 0.927 ENSMUST00000082170.5
 Fat3
FAT tumor suppressor homolog 3 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 9.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 3.0 GO:0007605 sensory perception of sound(GO:0007605)
0.2 2.8 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069)
0.4 2.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 2.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.5 1.9 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.4 1.7 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 1.7 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.5 1.6 GO:0070172 oculomotor nerve development(GO:0021557) positive regulation of tooth mineralization(GO:0070172)
0.0 1.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 1.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 0.9 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.0 0.9 GO:0010842 retina layer formation(GO:0010842)
0.0 0.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.2 0.7 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.7 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.7 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.2 0.6 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.6 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) glutamate secretion, neurotransmission(GO:0061535)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.2 GO:0016363 nuclear matrix(GO:0016363)
0.1 2.8 GO:0032420 stereocilium(GO:0032420) ciliary membrane(GO:0060170)
0.0 1.9 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.7 GO:1990032 parallel fiber(GO:1990032)
0.1 0.6 GO:0071437 invadopodium(GO:0071437)
0.1 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.4 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.3 GO:0070761 pre-snoRNP complex(GO:0070761)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 41 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.0 9.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.0 3.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.4 2.8 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.9 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.3 1.7 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 1.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.2 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.0 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.3 0.9 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.8 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.2 0.7 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.2 0.6 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)
0.2 0.6 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 0.6 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.6 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)