Motif ID: Nfatc3
Z-value: 1.462
Transcription factors associated with Nfatc3:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Nfatc3 | ENSMUSG00000031902.9 | Nfatc3 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Nfatc3 | mm10_v2_chr8_+_106059562_106059623 | -0.30 | 1.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 5.8 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.9 | 2.6 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
0.7 | 4.9 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
0.7 | 2.8 | GO:0060745 | mammary gland branching involved in pregnancy(GO:0060745) |
0.7 | 2.0 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) |
0.6 | 1.7 | GO:1903903 | striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903) |
0.6 | 1.7 | GO:0002302 | CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) |
0.5 | 2.5 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
0.4 | 1.2 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
0.4 | 1.6 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) positive regulation of isotype switching to IgG isotypes(GO:0048304) |
0.4 | 2.0 | GO:0060838 | lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
0.3 | 1.3 | GO:0010749 | regulation of nitric oxide mediated signal transduction(GO:0010749) |
0.3 | 1.0 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
0.3 | 1.6 | GO:0071205 | clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205) |
0.3 | 2.2 | GO:0072539 | T-helper 17 cell differentiation(GO:0072539) |
0.3 | 0.6 | GO:1905005 | regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905005) |
0.3 | 0.8 | GO:1900158 | negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
0.3 | 1.1 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.2 | 0.7 | GO:0033092 | positive regulation of immature T cell proliferation in thymus(GO:0033092) |
0.2 | 0.7 | GO:0031117 | positive regulation of microtubule depolymerization(GO:0031117) |
0.2 | 1.8 | GO:0046645 | positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645) positive regulation of uterine smooth muscle contraction(GO:0070474) |
0.2 | 0.7 | GO:2000977 | oculomotor nerve development(GO:0021557) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) regulation of forebrain neuron differentiation(GO:2000977) |
0.2 | 0.7 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
0.2 | 1.1 | GO:0019659 | lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661) |
0.2 | 0.6 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
0.2 | 3.6 | GO:0032060 | bleb assembly(GO:0032060) |
0.2 | 1.4 | GO:0051461 | protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
0.2 | 1.3 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
0.2 | 1.2 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
0.2 | 0.5 | GO:0042758 | long-chain fatty acid catabolic process(GO:0042758) |
0.2 | 0.8 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) |
0.2 | 0.5 | GO:0072554 | arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of heart induction(GO:1901321) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) |
0.1 | 1.8 | GO:0061179 | negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179) |
0.1 | 2.8 | GO:0060579 | ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581) |
0.1 | 1.2 | GO:0002536 | respiratory burst involved in inflammatory response(GO:0002536) |
0.1 | 1.7 | GO:0060159 | regulation of dopamine receptor signaling pathway(GO:0060159) |
0.1 | 0.5 | GO:0007412 | axon target recognition(GO:0007412) |
0.1 | 0.5 | GO:0044330 | canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096) |
0.1 | 1.0 | GO:0070836 | caveola assembly(GO:0070836) |
0.1 | 1.9 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.1 | 0.7 | GO:1901837 | negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837) |
0.1 | 0.8 | GO:0032808 | lacrimal gland development(GO:0032808) |
0.1 | 0.5 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.1 | 0.9 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
0.1 | 1.0 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
0.1 | 0.9 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
0.1 | 1.5 | GO:0051451 | myoblast migration(GO:0051451) |
0.1 | 0.6 | GO:0021814 | cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) |
0.1 | 0.4 | GO:0048539 | bone marrow development(GO:0048539) |
0.1 | 0.7 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
0.1 | 0.5 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) |
0.1 | 0.3 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
0.1 | 0.9 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
0.1 | 0.3 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
0.1 | 0.3 | GO:0070543 | response to linoleic acid(GO:0070543) |
0.1 | 0.6 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
0.1 | 0.4 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) |
0.1 | 1.4 | GO:0030575 | nuclear body organization(GO:0030575) |
0.1 | 0.2 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
0.1 | 0.4 | GO:0030091 | protein repair(GO:0030091) |
0.1 | 0.3 | GO:0001907 | killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) |
0.1 | 0.5 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
0.1 | 0.7 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
0.1 | 0.3 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.1 | 0.2 | GO:0019087 | transformation of host cell by virus(GO:0019087) |
0.1 | 0.4 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
0.1 | 1.4 | GO:0032981 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
0.1 | 0.7 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.1 | 0.8 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
0.1 | 0.7 | GO:0043586 | tongue development(GO:0043586) |
0.1 | 0.9 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
0.1 | 0.4 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.1 | 0.2 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.1 | 0.3 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.1 | 0.7 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.1 | 0.3 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
0.1 | 0.3 | GO:0090240 | positive regulation of histone H4 acetylation(GO:0090240) |
0.1 | 0.8 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
0.1 | 0.2 | GO:0007521 | muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596) |
0.1 | 0.4 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
0.1 | 0.7 | GO:0007530 | sex determination(GO:0007530) |
0.1 | 0.8 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
0.1 | 0.3 | GO:0002922 | positive regulation of humoral immune response(GO:0002922) progesterone receptor signaling pathway(GO:0050847) |
0.0 | 0.3 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
0.0 | 0.2 | GO:0035356 | cellular triglyceride homeostasis(GO:0035356) |
0.0 | 0.3 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 0.2 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
0.0 | 1.1 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
0.0 | 0.3 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
0.0 | 0.2 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.0 | 0.1 | GO:0009838 | abscission(GO:0009838) |
0.0 | 0.3 | GO:0042760 | very long-chain fatty acid catabolic process(GO:0042760) |
0.0 | 0.6 | GO:2000821 | synaptic vesicle maturation(GO:0016188) AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821) |
0.0 | 0.4 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 0.4 | GO:0010566 | regulation of ketone biosynthetic process(GO:0010566) |
0.0 | 0.2 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.0 | 0.3 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
0.0 | 0.4 | GO:0030836 | positive regulation of actin filament depolymerization(GO:0030836) positive regulation of protein depolymerization(GO:1901881) |
0.0 | 0.1 | GO:0014043 | negative regulation of neuron maturation(GO:0014043) |
0.0 | 1.0 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
0.0 | 0.3 | GO:0000963 | mitochondrial RNA processing(GO:0000963) |
0.0 | 0.1 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
0.0 | 0.2 | GO:0019348 | dolichol metabolic process(GO:0019348) |
0.0 | 0.1 | GO:0042822 | vitamin B6 metabolic process(GO:0042816) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) |
0.0 | 0.1 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.0 | 0.3 | GO:0050892 | intestinal absorption(GO:0050892) |
0.0 | 0.2 | GO:0009169 | purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) |
0.0 | 0.4 | GO:0006415 | translational termination(GO:0006415) |
0.0 | 0.1 | GO:0097298 | regulation of nucleus size(GO:0097298) |
0.0 | 0.6 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
0.0 | 0.2 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
0.0 | 0.8 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 0.2 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
0.0 | 0.5 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.1 | GO:0055071 | cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071) |
0.0 | 0.1 | GO:0006083 | acetate metabolic process(GO:0006083) |
0.0 | 0.5 | GO:0045116 | protein neddylation(GO:0045116) |
0.0 | 0.4 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
0.0 | 0.5 | GO:0001913 | T cell mediated cytotoxicity(GO:0001913) |
0.0 | 0.8 | GO:0015804 | neutral amino acid transport(GO:0015804) |
0.0 | 2.9 | GO:0051028 | mRNA transport(GO:0051028) |
0.0 | 0.9 | GO:0006801 | superoxide metabolic process(GO:0006801) |
0.0 | 0.1 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
0.0 | 0.1 | GO:0003345 | proepicardium cell migration involved in pericardium morphogenesis(GO:0003345) |
0.0 | 0.3 | GO:0060394 | negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394) |
0.0 | 0.1 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
0.0 | 0.5 | GO:0045214 | sarcomere organization(GO:0045214) |
0.0 | 0.1 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751) |
0.0 | 0.3 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
0.0 | 0.6 | GO:0097120 | receptor localization to synapse(GO:0097120) |
0.0 | 0.3 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 0.1 | GO:0071711 | basement membrane organization(GO:0071711) |
0.0 | 0.1 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
0.0 | 0.6 | GO:0060325 | face morphogenesis(GO:0060325) |
0.0 | 2.4 | GO:0048754 | branching morphogenesis of an epithelial tube(GO:0048754) |
0.0 | 0.1 | GO:0015840 | urea transport(GO:0015840) urea transmembrane transport(GO:0071918) |
0.0 | 0.4 | GO:0021904 | dorsal/ventral neural tube patterning(GO:0021904) |
0.0 | 0.1 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.0 | 1.1 | GO:0032024 | positive regulation of insulin secretion(GO:0032024) |
0.0 | 0.4 | GO:0042026 | protein refolding(GO:0042026) |
0.0 | 0.3 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
0.0 | 0.2 | GO:0060009 | Sertoli cell development(GO:0060009) |
0.0 | 0.4 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
0.0 | 0.1 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.0 | 0.1 | GO:0019532 | oxalate transport(GO:0019532) |
0.0 | 0.2 | GO:0006744 | ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.3 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 0.2 | GO:0010883 | regulation of lipid storage(GO:0010883) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.4 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
0.2 | 2.2 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.2 | 1.5 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.2 | 0.9 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.2 | 1.7 | GO:0030478 | actin cap(GO:0030478) |
0.2 | 0.7 | GO:0032021 | NELF complex(GO:0032021) |
0.2 | 0.8 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
0.2 | 2.8 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
0.2 | 0.5 | GO:0031417 | NatC complex(GO:0031417) |
0.1 | 3.6 | GO:0043218 | compact myelin(GO:0043218) |
0.1 | 1.1 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.1 | 2.3 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
0.1 | 0.4 | GO:1990130 | Iml1 complex(GO:1990130) |
0.1 | 0.5 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
0.1 | 1.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.1 | 0.6 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 1.9 | GO:0000242 | pericentriolar material(GO:0000242) |
0.1 | 1.1 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 0.8 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
0.1 | 0.4 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.1 | 0.6 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.1 | 0.3 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.1 | 0.7 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.1 | 0.6 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
0.0 | 0.3 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
0.0 | 1.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.2 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.0 | 0.6 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.0 | 0.4 | GO:0044292 | dendrite terminus(GO:0044292) |
0.0 | 0.9 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 0.9 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
0.0 | 1.8 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
0.0 | 1.4 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
0.0 | 1.2 | GO:0005719 | nuclear euchromatin(GO:0005719) |
0.0 | 0.7 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 1.0 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.4 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
0.0 | 0.3 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
0.0 | 0.5 | GO:0001741 | XY body(GO:0001741) |
0.0 | 0.1 | GO:0090543 | Flemming body(GO:0090543) |
0.0 | 6.1 | GO:0031012 | extracellular matrix(GO:0031012) |
0.0 | 0.5 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
0.0 | 0.7 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 1.0 | GO:0001669 | acrosomal vesicle(GO:0001669) |
0.0 | 0.3 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
0.0 | 0.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.2 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 0.6 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
0.0 | 0.7 | GO:0005876 | spindle microtubule(GO:0005876) |
0.0 | 0.5 | GO:0000315 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
0.0 | 0.1 | GO:0034709 | methylosome(GO:0034709) |
0.0 | 0.5 | GO:0031941 | filamentous actin(GO:0031941) |
0.0 | 0.9 | GO:0032432 | actin filament bundle(GO:0032432) |
0.0 | 0.7 | GO:0005643 | nuclear pore(GO:0005643) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 2.8 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.5 | 1.9 | GO:0008142 | oxysterol binding(GO:0008142) |
0.4 | 1.2 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.4 | 1.8 | GO:0042610 | CD8 receptor binding(GO:0042610) |
0.3 | 1.6 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
0.3 | 2.6 | GO:0001224 | RNA polymerase II transcription cofactor binding(GO:0001224) |
0.3 | 1.4 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.3 | 1.1 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
0.2 | 2.0 | GO:0001972 | retinoic acid binding(GO:0001972) |
0.2 | 1.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.1 | 2.5 | GO:0003708 | retinoic acid receptor activity(GO:0003708) |
0.1 | 0.6 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
0.1 | 1.0 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
0.1 | 0.5 | GO:0004096 | catalase activity(GO:0004096) |
0.1 | 1.7 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
0.1 | 0.5 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
0.1 | 0.5 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
0.1 | 0.7 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.1 | 0.7 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
0.1 | 3.1 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.1 | 0.5 | GO:0003998 | acylphosphatase activity(GO:0003998) |
0.1 | 0.3 | GO:0031896 | V2 vasopressin receptor binding(GO:0031896) |
0.1 | 0.6 | GO:0070320 | inward rectifier potassium channel inhibitor activity(GO:0070320) |
0.1 | 0.9 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
0.1 | 0.3 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
0.1 | 1.2 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.1 | 0.4 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
0.1 | 0.5 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
0.1 | 1.2 | GO:0008301 | DNA binding, bending(GO:0008301) |
0.1 | 0.4 | GO:0016149 | translation release factor activity, codon specific(GO:0016149) |
0.1 | 1.3 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.1 | 0.3 | GO:0001851 | complement component C3b binding(GO:0001851) proteinase activated receptor binding(GO:0031871) |
0.1 | 0.3 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.1 | 0.6 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
0.1 | 0.6 | GO:0031811 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
0.1 | 0.5 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
0.1 | 0.3 | GO:0046923 | ER retention sequence binding(GO:0046923) |
0.1 | 0.9 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.1 | 0.3 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
0.1 | 2.4 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 2.4 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.1 | 0.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.1 | 0.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 0.8 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
0.1 | 0.2 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
0.1 | 0.7 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.1 | 0.2 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.1 | 0.4 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
0.1 | 0.9 | GO:0016505 | peptidase activator activity involved in apoptotic process(GO:0016505) |
0.1 | 0.9 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
0.1 | 0.8 | GO:0031005 | filamin binding(GO:0031005) |
0.1 | 0.9 | GO:0008307 | structural constituent of muscle(GO:0008307) |
0.0 | 0.3 | GO:0043426 | MRF binding(GO:0043426) |
0.0 | 1.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.0 | 0.4 | GO:0048495 | Roundabout binding(GO:0048495) |
0.0 | 0.1 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
0.0 | 0.4 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.0 | 0.2 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.0 | 0.3 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 0.4 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
0.0 | 0.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
0.0 | 0.6 | GO:0070182 | DNA polymerase binding(GO:0070182) |
0.0 | 0.9 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.0 | 0.3 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
0.0 | 1.9 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
0.0 | 0.7 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
0.0 | 0.4 | GO:0034713 | type I transforming growth factor beta receptor binding(GO:0034713) |
0.0 | 0.6 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
0.0 | 0.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.0 | 0.5 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 1.7 | GO:0017022 | myosin binding(GO:0017022) |
0.0 | 0.4 | GO:0070403 | NAD+ binding(GO:0070403) |
0.0 | 0.6 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.4 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.0 | 0.1 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.0 | 0.1 | GO:0003987 | acetate-CoA ligase activity(GO:0003987) |
0.0 | 1.2 | GO:0035496 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062) |
0.0 | 0.4 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.3 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
0.0 | 1.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
0.0 | 1.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.0 | 0.1 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
0.0 | 0.2 | GO:0004622 | lysophospholipase activity(GO:0004622) |
0.0 | 0.1 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.0 | 0.1 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
0.0 | 0.3 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.0 | 0.6 | GO:0043394 | proteoglycan binding(GO:0043394) |
0.0 | 0.7 | GO:0035257 | nuclear hormone receptor binding(GO:0035257) |
0.0 | 0.7 | GO:0070888 | E-box binding(GO:0070888) |
0.0 | 0.1 | GO:0015265 | urea channel activity(GO:0015265) |
0.0 | 0.6 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.5 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
0.0 | 0.1 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
0.0 | 0.1 | GO:0008430 | selenium binding(GO:0008430) |
0.0 | 1.5 | GO:0035326 | enhancer binding(GO:0035326) |
0.0 | 0.2 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
0.0 | 0.3 | GO:0017161 | phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003) |
0.0 | 0.0 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.0 | 0.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
0.0 | 3.4 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
0.0 | 0.5 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
0.0 | 0.8 | GO:0000049 | tRNA binding(GO:0000049) |
0.0 | 0.2 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.0 | 0.1 | GO:0019956 | chemokine binding(GO:0019956) |
0.0 | 0.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 0.2 | GO:0001968 | fibronectin binding(GO:0001968) |
0.0 | 0.2 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 0.3 | GO:0018602 | sulfonate dioxygenase activity(GO:0000907) 2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity(GO:0018602) hypophosphite dioxygenase activity(GO:0034792) gibberellin 2-beta-dioxygenase activity(GO:0045543) C-19 gibberellin 2-beta-dioxygenase activity(GO:0052634) C-20 gibberellin 2-beta-dioxygenase activity(GO:0052635) |
0.0 | 1.0 | GO:0008013 | beta-catenin binding(GO:0008013) |
0.0 | 0.4 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |