Motif ID: Creb3l2

Z-value: 0.419


Transcription factors associated with Creb3l2:

Gene SymbolEntrez IDGene Name
Creb3l2 ENSMUSG00000038648.5 Creb3l2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb3l2mm10_v2_chr6_-_37442095_374421540.232.8e-01Click!


Activity profile for motif Creb3l2.

activity profile for motif Creb3l2


Sorted Z-values histogram for motif Creb3l2

Sorted Z-values for motif Creb3l2



Network of associatons between targets according to the STRING database.



First level regulatory network of Creb3l2

PNG image of the network

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Top targets:


Showing 1 to 20 of 141 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_128909866 0.983 ENSMUST00000026407.7
 Cd63
CD63 antigen
chrX_+_8271133 0.952 ENSMUST00000127103.1
ENSMUST00000115591.1
 Slc38a5

solute carrier family 38, member 5

chr11_+_100415697 0.821 ENSMUST00000001595.3
 Fkbp10
FK506 binding protein 10
chr6_-_22356068 0.820 ENSMUST00000163963.1
ENSMUST00000165576.1
 Fam3c

family with sequence similarity 3, member C

chr11_+_100415722 0.789 ENSMUST00000107400.2
 Fkbp10
FK506 binding protein 10
chr5_-_35679416 0.782 ENSMUST00000114233.2
 Htra3
HtrA serine peptidase 3
chr4_+_148591482 0.771 ENSMUST00000006611.8
 Srm
spermidine synthase
chr11_-_55033398 0.665 ENSMUST00000108883.3
ENSMUST00000102727.2
 Anxa6

annexin A6

chr12_+_112588753 0.637 ENSMUST00000101029.2
 Inf2
inverted formin, FH2 and WH2 domain containing
chr1_-_163725123 0.608 ENSMUST00000159679.1
 Mettl11b
methyltransferase like 11B
chr6_-_22356176 0.606 ENSMUST00000081288.7
 Fam3c
family with sequence similarity 3, member C
chr4_-_45084538 0.576 ENSMUST00000052236.6
 Fbxo10
F-box protein 10
chr4_-_149774238 0.567 ENSMUST00000105686.2
 Slc25a33
solute carrier family 25, member 33
chr3_+_104638658 0.564 ENSMUST00000046212.1
 Slc16a1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr6_-_101377342 0.557 ENSMUST00000151175.1
 Pdzrn3
PDZ domain containing RING finger 3
chr3_-_101604580 0.523 ENSMUST00000036493.6
 Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr15_-_97767644 0.511 ENSMUST00000128775.2
ENSMUST00000134885.2
 Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

chr4_-_108406676 0.507 ENSMUST00000184609.1
 Gpx7
glutathione peroxidase 7
chr6_+_56832059 0.463 ENSMUST00000031795.7
 Fkbp9
FK506 binding protein 9
chr9_+_89909775 0.434 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.2 1.0 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.1 1.0 GO:0015816 glycine transport(GO:0015816)
0.2 0.9 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.2 0.8 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.7 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.2 0.6 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.6 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.6 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.6 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.5 GO:1903416 response to glycoside(GO:1903416)
0.0 0.5 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.1 0.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.3 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.2 0.9 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 0.5 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.5 GO:0004096 catalase activity(GO:0004096)
0.1 0.5 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116) steroid hormone binding(GO:1990239)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.0 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)