Motif ID: Sox14

Z-value: 1.142


Transcription factors associated with Sox14:

Gene SymbolEntrez IDGene Name
Sox14 ENSMUSG00000053747.8 Sox14

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox14mm10_v2_chr9_-_99876147_998761930.048.6e-01Click!


Activity profile for motif Sox14.

activity profile for motif Sox14


Sorted Z-values histogram for motif Sox14

Sorted Z-values for motif Sox14



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox14

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 11.218 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr4_+_62965560 4.874 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
 Zfp618


zinc finger protein 618


chr12_+_109546333 4.621 ENSMUST00000166636.2
 Meg3
maternally expressed 3
chr12_+_109546409 4.250 ENSMUST00000143847.1
 Meg3
maternally expressed 3
chr4_+_13751297 3.945 ENSMUST00000105566.2
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_6980376 3.817 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr9_+_65265173 3.601 ENSMUST00000048762.1
 Cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr14_-_98169542 3.504 ENSMUST00000069334.7
ENSMUST00000071533.6
 Dach1

dachshund 1 (Drosophila)

chr14_-_104467984 3.452 ENSMUST00000053016.8
 Pou4f1
POU domain, class 4, transcription factor 1
chr11_-_12037391 3.331 ENSMUST00000093321.5
 Grb10
growth factor receptor bound protein 10
chr12_+_109545390 2.941 ENSMUST00000146701.1
 Meg3
maternally expressed 3
chrX_-_167209149 2.920 ENSMUST00000112176.1
 Tmsb4x
thymosin, beta 4, X chromosome
chr13_-_58113592 2.727 ENSMUST00000160860.1
 Klhl3
kelch-like 3
chr2_-_102186322 2.566 ENSMUST00000111222.1
ENSMUST00000058790.5
 Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr11_+_119022962 2.392 ENSMUST00000026662.7
 Cbx2
chromobox 2
chr11_+_69045640 2.271 ENSMUST00000108666.1
ENSMUST00000021277.5
 Aurkb

aurora kinase B

chr12_-_10900296 2.256 ENSMUST00000085735.2
 Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr1_+_146497614 2.249 ENSMUST00000132847.1
ENSMUST00000166814.1
 Brinp3

bone morphogenetic protein/retinoic acid inducible neural specific 3

chr7_-_144939823 2.244 ENSMUST00000093962.4
 Ccnd1
cyclin D1
chr13_+_5861489 2.097 ENSMUST00000000080.6
 Klf6
Kruppel-like factor 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 119 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 12.2 GO:0008340 determination of adult lifespan(GO:0008340)
1.9 11.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 5.3 GO:0008360 regulation of cell shape(GO:0008360)
0.1 3.9 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.7 3.5 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223) proprioception(GO:0019230)
0.4 3.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 3.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.4 3.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 3.0 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.3 2.9 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.9 2.7 GO:0003096 renal sodium ion transport(GO:0003096)
0.0 2.6 GO:0070613 regulation of protein processing(GO:0070613)
0.4 2.5 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 2.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.8 2.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.5 2.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 2.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.3 2.0 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 2.0 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.3 GO:0016363 nuclear matrix(GO:0016363)
0.0 4.0 GO:0005884 actin filament(GO:0005884)
0.2 3.7 GO:0035102 PRC1 complex(GO:0035102)
0.0 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.5 GO:0043034 costamere(GO:0043034)
0.5 2.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 2.3 GO:0043204 perikaryon(GO:0043204)
0.5 2.2 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.0 2.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.5 2.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 2.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 1.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.4 1.5 GO:0090537 CERF complex(GO:0090537)
0.3 1.5 GO:0008623 CHRAC(GO:0008623)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.5 GO:0005876 spindle microtubule(GO:0005876)
0.1 1.4 GO:0071564 npBAF complex(GO:0071564)
0.1 1.3 GO:0045298 tubulin complex(GO:0045298)
0.0 1.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 90 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.9 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 5.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 5.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 4.0 GO:0005080 protein kinase C binding(GO:0005080)
0.0 3.7 GO:0051015 actin filament binding(GO:0051015)
0.1 3.6 GO:0035064 methylated histone binding(GO:0035064)
1.2 3.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 3.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 3.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 3.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 3.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.9 GO:0070064 proline-rich region binding(GO:0070064)
0.1 2.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.4 2.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.3 2.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.3 2.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.4 2.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 2.0 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 1.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)