Motif ID: Nr0b1

Z-value: 0.447


Transcription factors associated with Nr0b1:

Gene SymbolEntrez IDGene Name
Nr0b1 ENSMUSG00000025056.4 Nr0b1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nr0b1mm10_v2_chrX_+_86191764_861917820.282.0e-01Click!


Activity profile for motif Nr0b1.

activity profile for motif Nr0b1


Sorted Z-values histogram for motif Nr0b1

Sorted Z-values for motif Nr0b1



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr0b1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_42697146 1.670 ENSMUST00000054883.2
Pou3f3
POU domain, class 3, transcription factor 3
chr3_+_54156039 1.458 ENSMUST00000029311.6
Trpc4
transient receptor potential cation channel, subfamily C, member 4
chr5_+_64803513 0.963 ENSMUST00000165536.1
Klf3
Kruppel-like factor 3 (basic)
chr9_+_80165013 0.781 ENSMUST00000035889.8
ENSMUST00000113268.1
Myo6

myosin VI

chr9_+_80165079 0.767 ENSMUST00000184480.1
Myo6
myosin VI
chr13_-_94358818 0.662 ENSMUST00000059598.2
Gm9776
predicted gene 9776
chr11_+_77930800 0.615 ENSMUST00000093995.3
ENSMUST00000000646.7
Sez6

seizure related gene 6

chr10_-_127666673 0.580 ENSMUST00000026469.2
Nab2
Ngfi-A binding protein 2
chr4_+_148130883 0.496 ENSMUST00000084129.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr11_-_70687917 0.444 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr4_-_148130678 0.398 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr10_+_39732099 0.393 ENSMUST00000019986.6
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr5_-_115436508 0.378 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr7_+_19359740 0.376 ENSMUST00000140836.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr10_+_38965515 0.367 ENSMUST00000019992.5
Lama4
laminin, alpha 4
chr13_+_94358943 0.353 ENSMUST00000022196.3
Ap3b1
adaptor-related protein complex 3, beta 1 subunit
chr11_+_23306884 0.349 ENSMUST00000180046.1
Usp34
ubiquitin specific peptidase 34
chr1_+_162570687 0.338 ENSMUST00000050010.4
ENSMUST00000150040.1
Vamp4

vesicle-associated membrane protein 4

chr7_-_65371210 0.335 ENSMUST00000102592.3
Tjp1
tight junction protein 1
chr16_+_44173239 0.333 ENSMUST00000119746.1
Gm608
predicted gene 608
chr19_+_37550397 0.319 ENSMUST00000066439.6
Exoc6
exocyst complex component 6
chr15_-_38078842 0.315 ENSMUST00000110336.2
Ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr7_+_28180272 0.289 ENSMUST00000173223.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_+_23306910 0.288 ENSMUST00000137823.1
Usp34
ubiquitin specific peptidase 34
chr7_+_28180226 0.283 ENSMUST00000172467.1
Dyrk1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr2_+_4718145 0.269 ENSMUST00000056914.6
Bend7
BEN domain containing 7
chr4_+_116221633 0.259 ENSMUST00000030464.7
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr5_+_110230975 0.255 ENSMUST00000031474.7
ENSMUST00000086674.5
Ankle2

ankyrin repeat and LEM domain containing 2

chr3_-_86920830 0.253 ENSMUST00000029719.8
Dclk2
doublecortin-like kinase 2
chr13_-_29984219 0.250 ENSMUST00000146092.1
E2f3
E2F transcription factor 3
chr3_+_86224665 0.248 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr6_+_134830145 0.230 ENSMUST00000046303.5
Crebl2
cAMP responsive element binding protein-like 2
chr17_+_88530113 0.226 ENSMUST00000038551.6
Ppp1r21
protein phosphatase 1, regulatory subunit 21
chr13_-_106936907 0.221 ENSMUST00000080856.7
Ipo11
importin 11
chr2_+_71786923 0.191 ENSMUST00000112101.1
ENSMUST00000028522.3
Itga6

integrin alpha 6

chr5_+_30913398 0.190 ENSMUST00000031055.5
Emilin1
elastin microfibril interfacer 1
chr12_+_49385174 0.183 ENSMUST00000110746.1
3110039M20Rik
RIKEN cDNA 3110039M20 gene
chr9_+_110333402 0.179 ENSMUST00000133114.1
ENSMUST00000125759.1
Scap

SREBF chaperone

chr8_-_95434869 0.179 ENSMUST00000034249.6
Gtl3
gene trap locus 3
chr16_+_35154870 0.179 ENSMUST00000114913.1
Adcy5
adenylate cyclase 5
chr6_+_47454320 0.177 ENSMUST00000031697.8
Cul1
cullin 1
chr9_-_109059711 0.173 ENSMUST00000061973.4
Trex1
three prime repair exonuclease 1
chr4_+_116221590 0.171 ENSMUST00000147292.1
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr15_+_80711292 0.170 ENSMUST00000067689.7
Tnrc6b
trinucleotide repeat containing 6b
chr4_+_116221689 0.162 ENSMUST00000106490.2
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr7_+_82867327 0.151 ENSMUST00000082237.5
Mex3b
mex3 homolog B (C. elegans)
chr9_-_44881274 0.150 ENSMUST00000002095.3
ENSMUST00000114689.1
ENSMUST00000128768.1
Kmt2a


lysine (K)-specific methyltransferase 2A


chrX_-_73659724 0.146 ENSMUST00000114473.1
ENSMUST00000002087.7
Pnck

pregnancy upregulated non-ubiquitously expressed CaM kinase

chr3_-_123690806 0.140 ENSMUST00000154668.1
Ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr3_+_89715016 0.138 ENSMUST00000098924.2
Adar
adenosine deaminase, RNA-specific
chr17_-_80728026 0.128 ENSMUST00000112389.2
ENSMUST00000025089.7
Map4k3

mitogen-activated protein kinase kinase kinase kinase 3

chr8_-_105707933 0.117 ENSMUST00000013299.9
Enkd1
enkurin domain containing 1
chr13_+_41249841 0.116 ENSMUST00000165561.2
Smim13
small integral membrane protein 13
chr2_-_80581380 0.114 ENSMUST00000111760.2
Nckap1
NCK-associated protein 1
chr11_+_107547925 0.107 ENSMUST00000100305.1
ENSMUST00000075012.1
ENSMUST00000106746.1
Helz


helicase with zinc finger domain


chr9_-_110117379 0.104 ENSMUST00000111991.2
ENSMUST00000149199.1
ENSMUST00000035056.7
ENSMUST00000148287.1
ENSMUST00000127744.1
Dhx30




DEAH (Asp-Glu-Ala-His) box polypeptide 30




chr7_-_80371197 0.101 ENSMUST00000098346.3
Man2a2
mannosidase 2, alpha 2
chr14_+_75845296 0.098 ENSMUST00000142061.1
Tpt1
tumor protein, translationally-controlled 1
chr2_-_80581234 0.097 ENSMUST00000028386.5
Nckap1
NCK-associated protein 1
chr1_+_59764264 0.080 ENSMUST00000087435.5
Bmpr2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr1_+_140246216 0.079 ENSMUST00000119786.1
ENSMUST00000120796.1
ENSMUST00000060201.8
ENSMUST00000120709.1
Kcnt2



potassium channel, subfamily T, member 2



chr6_+_134830216 0.078 ENSMUST00000111937.1
Crebl2
cAMP responsive element binding protein-like 2
chr11_+_94327984 0.076 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40

ankyrin repeat domain 40

chr8_-_85080679 0.070 ENSMUST00000093357.5
Wdr83
WD repeat domain containing 83
chr8_-_85080652 0.064 ENSMUST00000152785.1
Wdr83
WD repeat domain containing 83
chr11_+_105181793 0.062 ENSMUST00000092537.3
ENSMUST00000015107.6
ENSMUST00000145048.1
Tlk2


tousled-like kinase 2 (Arabidopsis)


chr4_-_129696817 0.053 ENSMUST00000102588.3
Tmem39b
transmembrane protein 39b
chr10_-_81350389 0.052 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr17_+_26252915 0.052 ENSMUST00000114976.2
ENSMUST00000140427.1
ENSMUST00000119928.1
Luc7l


Luc7 homolog (S. cerevisiae)-like


chr17_-_57059795 0.052 ENSMUST00000040280.7
Slc25a23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr10_+_116301374 0.050 ENSMUST00000092167.5
Ptprb
protein tyrosine phosphatase, receptor type, B
chrX_-_48034842 0.047 ENSMUST00000039026.7
Apln
apelin
chr4_-_132422394 0.046 ENSMUST00000152271.1
ENSMUST00000084170.5
Phactr4

phosphatase and actin regulator 4

chr4_-_132422484 0.044 ENSMUST00000102568.3
Phactr4
phosphatase and actin regulator 4
chr15_+_35371498 0.043 ENSMUST00000048646.7
Vps13b
vacuolar protein sorting 13B (yeast)
chr11_+_102604370 0.041 ENSMUST00000057893.5
Fzd2
frizzled homolog 2 (Drosophila)
chr7_+_79500081 0.040 ENSMUST00000181511.2
ENSMUST00000182937.1
AI854517

expressed sequence AI854517

chr17_-_84790517 0.039 ENSMUST00000112308.2
Lrpprc
leucine-rich PPR-motif containing
chr18_+_80046854 0.037 ENSMUST00000070219.7
Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr11_-_74723829 0.030 ENSMUST00000102520.2
Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr11_+_105181527 0.028 ENSMUST00000106941.2
Tlk2
tousled-like kinase 2 (Arabidopsis)
chr3_-_139075178 0.025 ENSMUST00000098574.2
ENSMUST00000029796.6
Rap1gds1

RAP1, GTP-GDP dissociation stimulator 1

chr5_+_31193227 0.006 ENSMUST00000031029.8
ENSMUST00000133711.1
ENSMUST00000132471.1
Snx17


sorting nexin 17



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0072070 loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.3 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.4 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.4 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 0.6 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 1.5 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.2 GO:0007354 zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 0.2 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.1 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.3 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.6 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.4 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0097274 urea homeostasis(GO:0097274)
0.0 0.1 GO:1902669 positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.0 0.2 GO:0016197 endosomal transport(GO:0016197)
0.0 0.6 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.0 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0005605 basal lamina(GO:0005605)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0097440 apical dendrite(GO:0097440)
0.0 0.1 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.0 1.5 GO:0005901 caveola(GO:0005901)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0003692 left-handed Z-DNA binding(GO:0003692)
0.0 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.5 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)