Motif ID: Plagl1

Z-value: 0.417


Transcription factors associated with Plagl1:

Gene SymbolEntrez IDGene Name
Plagl1 ENSMUSG00000019817.12 Plagl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Plagl1mm10_v2_chr10_+_13090788_13090843-0.556.3e-03Click!


Activity profile for motif Plagl1.

activity profile for motif Plagl1


Sorted Z-values histogram for motif Plagl1

Sorted Z-values for motif Plagl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Plagl1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_139092958 0.866 ENSMUST00000042844.6
 Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr10_+_38965515 0.811 ENSMUST00000019992.5
 Lama4
laminin, alpha 4
chr6_-_91807424 0.667 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chr6_+_4504814 0.666 ENSMUST00000141483.1
 Col1a2
collagen, type I, alpha 2
chr17_+_46297406 0.639 ENSMUST00000061722.6
ENSMUST00000166280.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr3_-_108017877 0.558 ENSMUST00000004140.4
 Gstm1
glutathione S-transferase, mu 1
chr3_-_108017806 0.528 ENSMUST00000126593.1
 Gstm1
glutathione S-transferase, mu 1
chr4_+_129136948 0.499 ENSMUST00000102600.3
 Fndc5
fibronectin type III domain containing 5
chr17_-_24644933 0.498 ENSMUST00000019684.5
 Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr7_-_99695809 0.458 ENSMUST00000107086.2
 Slco2b1
solute carrier organic anion transporter family, member 2b1
chr11_+_53519725 0.451 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
 Sept8


septin 8


chr4_+_152338619 0.451 ENSMUST00000030775.5
ENSMUST00000164662.1
 Chd5

chromodomain helicase DNA binding protein 5

chr6_-_91807318 0.450 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr9_+_75625707 0.421 ENSMUST00000034702.4
 Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr17_+_46297917 0.412 ENSMUST00000166617.1
ENSMUST00000170271.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr5_-_139130159 0.381 ENSMUST00000129851.1
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr5_-_136883115 0.352 ENSMUST00000057497.6
ENSMUST00000111103.1
 Col26a1

collagen, type XXVI, alpha 1

chr11_-_120047144 0.349 ENSMUST00000103020.1
 Aatk
apoptosis-associated tyrosine kinase
chr11_+_53519920 0.346 ENSMUST00000147912.1
 Sept8
septin 8
chr3_+_26331150 0.344 ENSMUST00000099182.2
 A830092H15Rik
RIKEN cDNA A830092H15 gene
chr4_+_148160613 0.320 ENSMUST00000047951.8
 Fbxo2
F-box protein 2
chr10_-_81014902 0.318 ENSMUST00000126317.1
ENSMUST00000092285.3
ENSMUST00000117805.1
 Gng7


guanine nucleotide binding protein (G protein), gamma 7


chr17_-_25868727 0.301 ENSMUST00000026828.5
 Fam195a
family with sequence similarity 195, member A
chr5_-_34187670 0.299 ENSMUST00000042701.6
ENSMUST00000119171.1
 Mxd4

Max dimerization protein 4

chr11_+_53519871 0.292 ENSMUST00000120878.2
 Sept8
septin 8
chr6_-_128143525 0.269 ENSMUST00000032503.5
ENSMUST00000112173.1
 Tspan9

tetraspanin 9

chr19_+_5474681 0.247 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
 Efemp2




epidermal growth factor-containing fibulin-like extracellular matrix protein 2




chr11_+_98741805 0.229 ENSMUST00000064187.5
 Thra
thyroid hormone receptor alpha
chr19_-_4625612 0.227 ENSMUST00000025823.3
 Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr7_+_5015466 0.214 ENSMUST00000086349.3
 Zfp524
zinc finger protein 524
chr11_+_98741871 0.214 ENSMUST00000103139.4
 Thra
thyroid hormone receptor alpha
chr7_+_142533012 0.214 ENSMUST00000038675.6
 Mrpl23
mitochondrial ribosomal protein L23
chr5_-_136567242 0.212 ENSMUST00000175975.2
ENSMUST00000176216.2
ENSMUST00000176745.1
 Cux1


cut-like homeobox 1


chrX_-_37085402 0.200 ENSMUST00000115231.3
 Rpl39
ribosomal protein L39
chr5_+_125475814 0.197 ENSMUST00000031445.3
 Aacs
acetoacetyl-CoA synthetase
chr2_-_104257400 0.196 ENSMUST00000141159.1
 D430041D05Rik
RIKEN cDNA D430041D05 gene
chrX_-_73824938 0.195 ENSMUST00000114438.2
ENSMUST00000002080.5
 Pdzd4

PDZ domain containing 4

chr12_-_103443653 0.191 ENSMUST00000055071.8
 Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
chr5_+_24393640 0.179 ENSMUST00000138168.1
ENSMUST00000115077.1
 Abcb8

ATP-binding cassette, sub-family B (MDR/TAP), member 8

chr2_-_3419019 0.177 ENSMUST00000115084.1
ENSMUST00000115083.1
 Meig1

meiosis expressed gene 1

chrX_+_163911401 0.172 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr2_-_155592567 0.167 ENSMUST00000155347.1
ENSMUST00000130881.1
ENSMUST00000079691.6
 Gss


glutathione synthetase


chrX_+_20870166 0.167 ENSMUST00000115342.3
ENSMUST00000009530.4
 Timp1

tissue inhibitor of metalloproteinase 1

chr15_-_99251929 0.159 ENSMUST00000041190.9
ENSMUST00000163506.1
 Mcrs1

microspherule protein 1

chr11_+_67966442 0.157 ENSMUST00000021286.4
ENSMUST00000108675.1
 Stx8

syntaxin 8

chr19_+_6497772 0.156 ENSMUST00000113458.1
ENSMUST00000113459.1
 Nrxn2

neurexin II

chr15_-_52478228 0.155 ENSMUST00000081993.1
 Gm10020
predicted pseudogene 10020
chr15_+_75993756 0.154 ENSMUST00000089669.4
 Mapk15
mitogen-activated protein kinase 15
chr8_-_13974715 0.153 ENSMUST00000119182.1
ENSMUST00000062613.4
 Tdrp

testis development related protein

chr18_+_32377176 0.143 ENSMUST00000091967.5
ENSMUST00000025239.7
 Bin1

bridging integrator 1

chr2_-_132145057 0.137 ENSMUST00000028815.8
 Slc23a2
solute carrier family 23 (nucleobase transporters), member 2
chr8_+_93810832 0.137 ENSMUST00000034198.8
ENSMUST00000125716.1
 Gnao1

guanine nucleotide binding protein, alpha O

chr11_+_32455362 0.136 ENSMUST00000051053.4
 Ubtd2
ubiquitin domain containing 2
chr9_+_108662098 0.133 ENSMUST00000035222.5
 Slc25a20
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr7_-_139616309 0.129 ENSMUST00000166503.1
ENSMUST00000093991.3
 E030019B06Rik

RIKEN cDNA E030019B06 gene

chr1_+_74588347 0.124 ENSMUST00000113732.1
 Bcs1l
BCS1-like (yeast)
chr6_+_40325471 0.122 ENSMUST00000031977.8
 Agk
acylglycerol kinase
chr2_-_130642770 0.120 ENSMUST00000045761.6
 Lzts3
leucine zipper, putative tumor suppressor family member 3
chr6_-_124712131 0.118 ENSMUST00000004379.5
 Emg1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr2_-_3419066 0.117 ENSMUST00000115082.3
 Meig1
meiosis expressed gene 1
chr6_+_110645572 0.114 ENSMUST00000071076.6
ENSMUST00000172951.1
 Grm7

glutamate receptor, metabotropic 7

chr7_+_45872772 0.113 ENSMUST00000002855.5
ENSMUST00000107719.1
 Kdelr1

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

chr11_+_70018421 0.111 ENSMUST00000108588.1
 Dlg4
discs, large homolog 4 (Drosophila)
chr4_+_47288057 0.111 ENSMUST00000140413.1
ENSMUST00000107731.2
 Col15a1

collagen, type XV, alpha 1

chr1_+_134455524 0.110 ENSMUST00000112232.1
ENSMUST00000027725.4
ENSMUST00000116528.1
 Klhl12


kelch-like 12


chr16_-_32099697 0.109 ENSMUST00000155966.1
ENSMUST00000096109.4
 Pigx

phosphatidylinositol glycan anchor biosynthesis, class X

chr11_+_87699897 0.106 ENSMUST00000040089.4
 Rnf43
ring finger protein 43
chr17_-_84682932 0.104 ENSMUST00000066175.3
 Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr6_+_124712279 0.103 ENSMUST00000004375.9
 Phb2
prohibitin 2
chr1_-_120074023 0.101 ENSMUST00000056089.7
 Tmem37
transmembrane protein 37
chr5_-_123012874 0.100 ENSMUST00000172729.1
 Kdm2b
lysine (K)-specific demethylase 2B
chr17_+_25016343 0.099 ENSMUST00000024983.5
 Ift140
intraflagellar transport 140
chr5_-_124352233 0.097 ENSMUST00000111472.1
 Cdk2ap1
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr1_+_74588289 0.097 ENSMUST00000113733.3
ENSMUST00000027358.4
 Bcs1l

BCS1-like (yeast)

chr6_-_56704673 0.093 ENSMUST00000170382.2
 Lsm5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_-_120727226 0.087 ENSMUST00000106148.3
ENSMUST00000026144.4
 Dcxr

dicarbonyl L-xylulose reductase

chr4_+_155249960 0.083 ENSMUST00000178473.1
ENSMUST00000105627.1
ENSMUST00000097747.2
 2610002J02Rik


RIKEN cDNA 2610002J02 gene


chr6_+_128438757 0.081 ENSMUST00000144745.1
 Gm10069
predicted gene 10069
chr16_+_91406235 0.080 ENSMUST00000023691.5
 Il10rb
interleukin 10 receptor, beta
chr9_+_72806874 0.072 ENSMUST00000055535.8
 Prtg
protogenin homolog (Gallus gallus)
chr8_-_25101985 0.066 ENSMUST00000128715.1
ENSMUST00000064883.6
 Plekha2

pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2

chr14_+_70774304 0.066 ENSMUST00000022698.7
 Dok2
docking protein 2
chr17_-_35115428 0.065 ENSMUST00000172854.1
ENSMUST00000062657.4
 Ly6g5b

lymphocyte antigen 6 complex, locus G5B

chr9_+_46273064 0.063 ENSMUST00000156440.1
ENSMUST00000034583.6
ENSMUST00000114552.3
 Zfp259


zinc finger protein 259


chr15_-_82244716 0.061 ENSMUST00000089155.4
ENSMUST00000089157.3
 Cenpm

centromere protein M

chr17_+_24736673 0.061 ENSMUST00000101800.5
 Msrb1
methionine sulfoxide reductase B1
chr11_+_95010277 0.060 ENSMUST00000124735.1
 Samd14
sterile alpha motif domain containing 14
chr5_-_143269958 0.060 ENSMUST00000161448.1
 Zfp316
zinc finger protein 316
chr17_+_24736639 0.059 ENSMUST00000115262.1
 Msrb1
methionine sulfoxide reductase B1
chr2_-_152332639 0.059 ENSMUST00000028964.7
 Rbck1
RanBP-type and C3HC4-type zinc finger containing 1
chr17_+_29549783 0.056 ENSMUST00000048677.7
 Tbc1d22b
TBC1 domain family, member 22B
chr12_-_56535047 0.052 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chrX_+_99821021 0.049 ENSMUST00000096363.2
 Tmem28
transmembrane protein 28
chr6_-_48086530 0.046 ENSMUST00000073124.6
 Zfp746
zinc finger protein 746
chr5_-_24577467 0.045 ENSMUST00000030795.8
 Abcf2
ATP-binding cassette, sub-family F (GCN20), member 2
chr13_+_5861489 0.042 ENSMUST00000000080.6
 Klf6
Kruppel-like factor 6
chr12_+_99884498 0.040 ENSMUST00000153627.1
 Tdp1
tyrosyl-DNA phosphodiesterase 1
chr3_-_96727436 0.040 ENSMUST00000154679.1
 Polr3c
polymerase (RNA) III (DNA directed) polypeptide C
chr10_-_128547722 0.039 ENSMUST00000040572.3
 Zc3h10
zinc finger CCCH type containing 10
chr6_-_128200598 0.037 ENSMUST00000071101.6
 Gm10010
predicted gene 10010
chr13_-_35027077 0.037 ENSMUST00000170538.1
ENSMUST00000163280.1
 Eci2

enoyl-Coenzyme A delta isomerase 2

chr19_+_45047557 0.036 ENSMUST00000062213.5
ENSMUST00000111954.4
ENSMUST00000084493.6
 Sfxn3


sideroflexin 3


chr1_-_88205674 0.035 ENSMUST00000119972.2
 Dnajb3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr17_+_29032664 0.030 ENSMUST00000130216.1
 Srsf3
serine/arginine-rich splicing factor 3
chr2_-_152830615 0.024 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
 Bcl2l1



BCL2-like 1



chr2_+_25428699 0.023 ENSMUST00000102919.3
 Abca2
ATP-binding cassette, sub-family A (ABC1), member 2
chr17_-_25274299 0.021 ENSMUST00000172587.1
ENSMUST00000049911.9
ENSMUST00000173713.1
 Ube2i


ubiquitin-conjugating enzyme E2I


chr4_-_22488296 0.020 ENSMUST00000178174.1
 Pou3f2
POU domain, class 3, transcription factor 2
chr6_-_128438673 0.017 ENSMUST00000032508.4
 Fkbp4
FK506 binding protein 4
chr17_+_35126316 0.016 ENSMUST00000061859.6
 D17H6S53E
DNA segment, Chr 17, human D6S53E
chr10_-_81350389 0.016 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
 Hmg20b



high mobility group 20B



chr10_-_70599284 0.014 ENSMUST00000046513.3
 Phyhipl
phytanoyl-CoA hydroxylase interacting protein-like
chr12_+_100199435 0.014 ENSMUST00000110082.3
 Calm1
calmodulin 1
chr17_+_37193889 0.010 ENSMUST00000038844.6
 Ubd
ubiquitin D
chr10_-_81350305 0.010 ENSMUST00000167481.1
 Hmg20b
high mobility group 20B
chr4_-_45489794 0.010 ENSMUST00000146236.1
 Shb
src homology 2 domain-containing transforming protein B
chr1_-_179546261 0.008 ENSMUST00000027769.5
 Tfb2m
transcription factor B2, mitochondrial
chr19_+_4711153 0.007 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr1_-_128103016 0.005 ENSMUST00000097597.2
 Zranb3
zinc finger, RAN-binding domain containing 3
chr5_-_134456227 0.004 ENSMUST00000111244.1
 Gtf2ird1
general transcription factor II I repeat domain-containing 1
chr6_+_83179568 0.004 ENSMUST00000113919.3
ENSMUST00000113918.1
ENSMUST00000141680.1
 Dctn1


dynactin 1


chr2_-_152831112 0.002 ENSMUST00000128172.1
 Bcl2l1
BCL2-like 1
chr2_-_18998126 0.001 ENSMUST00000006912.5
 Pip4k2a
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr7_-_19271797 0.000 ENSMUST00000032561.8
 Vasp
vasodilator-stimulated phosphoprotein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 0.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 1.1 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.1 0.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.7 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.1 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0060744 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0070475 nucleolus organization(GO:0007000) rRNA base methylation(GO:0070475)
0.0 0.1 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.8 GO:0005605 basal lamina(GO:0005605)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0016015 morphogen activity(GO:0016015)
0.1 0.4 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 1.1 GO:0016151 nickel cation binding(GO:0016151)
0.1 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 1.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)