Motif ID: Plagl1

Z-value: 0.417


Transcription factors associated with Plagl1:

Gene SymbolEntrez IDGene Name
Plagl1 ENSMUSG00000019817.12 Plagl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Plagl1mm10_v2_chr10_+_13090788_13090843-0.556.3e-03Click!


Activity profile for motif Plagl1.

activity profile for motif Plagl1


Sorted Z-values histogram for motif Plagl1

Sorted Z-values for motif Plagl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Plagl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 124 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_139092958 0.866 ENSMUST00000042844.6
 Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr10_+_38965515 0.811 ENSMUST00000019992.5
 Lama4
laminin, alpha 4
chr6_-_91807424 0.667 ENSMUST00000162300.1
 Grip2
glutamate receptor interacting protein 2
chr6_+_4504814 0.666 ENSMUST00000141483.1
 Col1a2
collagen, type I, alpha 2
chr17_+_46297406 0.639 ENSMUST00000061722.6
ENSMUST00000166280.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr3_-_108017877 0.558 ENSMUST00000004140.4
 Gstm1
glutathione S-transferase, mu 1
chr3_-_108017806 0.528 ENSMUST00000126593.1
 Gstm1
glutathione S-transferase, mu 1
chr4_+_129136948 0.499 ENSMUST00000102600.3
 Fndc5
fibronectin type III domain containing 5
chr17_-_24644933 0.498 ENSMUST00000019684.5
 Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr7_-_99695809 0.458 ENSMUST00000107086.2
 Slco2b1
solute carrier organic anion transporter family, member 2b1
chr11_+_53519725 0.451 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
 Sept8


septin 8


chr4_+_152338619 0.451 ENSMUST00000030775.5
ENSMUST00000164662.1
 Chd5

chromodomain helicase DNA binding protein 5

chr6_-_91807318 0.450 ENSMUST00000159684.1
 Grip2
glutamate receptor interacting protein 2
chr9_+_75625707 0.421 ENSMUST00000034702.4
 Lysmd2
LysM, putative peptidoglycan-binding, domain containing 2
chr17_+_46297917 0.412 ENSMUST00000166617.1
ENSMUST00000170271.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr5_-_139130159 0.381 ENSMUST00000129851.1
 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr5_-_136883115 0.352 ENSMUST00000057497.6
ENSMUST00000111103.1
 Col26a1

collagen, type XXVI, alpha 1

chr11_-_120047144 0.349 ENSMUST00000103020.1
 Aatk
apoptosis-associated tyrosine kinase
chr11_+_53519920 0.346 ENSMUST00000147912.1
 Sept8
septin 8
chr3_+_26331150 0.344 ENSMUST00000099182.2
 A830092H15Rik
RIKEN cDNA A830092H15 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.1 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 1.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 0.9 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 0.7 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.3 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:1904749 regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.8 GO:0005605 basal lamina(GO:0005605)
0.2 0.7 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0035254 glutamate receptor binding(GO:0035254)
0.1 1.1 GO:0016151 nickel cation binding(GO:0016151)
0.3 0.9 GO:0016015 morphogen activity(GO:0016015)
0.0 0.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 0.4 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)