Motif ID: Nr2f6
Z-value: 0.678
Transcription factors associated with Nr2f6:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Nr2f6 | ENSMUSG00000002393.8 | Nr2f6 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Nr2f6 | mm10_v2_chr8_-_71381907_71381977 | -0.57 | 4.2e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 2.3 | GO:0003360 | brainstem development(GO:0003360) |
| 0.5 | 2.1 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.3 | 3.1 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.2 | 0.7 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.2 | 0.6 | GO:0050748 | negative regulation of lipoprotein metabolic process(GO:0050748) |
| 0.2 | 0.9 | GO:1902031 | regulation of NADP metabolic process(GO:1902031) |
| 0.2 | 0.5 | GO:0071929 | alpha-tubulin acetylation(GO:0071929) |
| 0.1 | 1.6 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.1 | 0.4 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
| 0.1 | 0.3 | GO:0001193 | maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193) |
| 0.1 | 0.4 | GO:0060334 | regulation of interferon-gamma-mediated signaling pathway(GO:0060334) |
| 0.1 | 0.5 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.1 | 2.9 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.1 | 0.7 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.1 | 0.2 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.1 | 0.2 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.1 | 0.3 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.1 | 0.9 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 0.4 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 0.1 | 1.0 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 0.3 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 0.3 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
| 0.1 | 0.3 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.5 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.0 | 0.1 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
| 0.0 | 0.4 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.5 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
| 0.0 | 0.3 | GO:0019321 | pentose metabolic process(GO:0019321) |
| 0.0 | 0.2 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.0 | 1.5 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.6 | GO:0010566 | regulation of ketone biosynthetic process(GO:0010566) |
| 0.0 | 1.8 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.0 | 0.1 | GO:0071335 | negative regulation of Schwann cell proliferation(GO:0010626) hair follicle cell proliferation(GO:0071335) |
| 0.0 | 1.8 | GO:0008156 | negative regulation of DNA replication(GO:0008156) |
| 0.0 | 0.1 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
| 0.0 | 0.7 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 0.5 | GO:0010800 | positive regulation of peptidyl-threonine phosphorylation(GO:0010800) |
| 0.0 | 0.1 | GO:1904668 | positive regulation of ubiquitin protein ligase activity(GO:1904668) |
| 0.0 | 0.5 | GO:0032292 | myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292) |
| 0.0 | 0.3 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 0.0 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) |
| 0.0 | 0.0 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.0 | 0.1 | GO:0010561 | negative regulation of glycoprotein biosynthetic process(GO:0010561) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.3 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.2 | 0.6 | GO:1990879 | CST complex(GO:1990879) |
| 0.2 | 1.6 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.1 | 0.9 | GO:0031314 | mitochondrial inner membrane presequence translocase complex(GO:0005744) extrinsic component of mitochondrial inner membrane(GO:0031314) |
| 0.1 | 0.6 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.1 | 0.7 | GO:0034715 | U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715) |
| 0.1 | 0.5 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.1 | 0.3 | GO:0045251 | mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251) |
| 0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 0.4 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 0.5 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 1.6 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 0.6 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 1.6 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.4 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.0 | 1.0 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 1.1 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.3 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.3 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.6 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.1 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 0.1 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 0.0 | 0.4 | GO:0030120 | vesicle coat(GO:0030120) |
| 0.0 | 0.3 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.3 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.4 | 1.5 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.3 | 0.9 | GO:0004471 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) |
| 0.2 | 0.7 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.1 | 0.3 | GO:0004658 | propionyl-CoA carboxylase activity(GO:0004658) |
| 0.1 | 0.3 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.1 | 0.3 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.1 | 0.5 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.1 | 0.6 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.1 | 0.5 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
| 0.0 | 0.4 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 1.8 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.6 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 0.4 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.0 | 0.6 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 0.5 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.0 | 0.3 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 1.9 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 1.6 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.0 | 0.5 | GO:0004438 | phosphatidylinositol-3-phosphatase activity(GO:0004438) |
| 0.0 | 0.2 | GO:0015651 | quaternary ammonium group transmembrane transporter activity(GO:0015651) |
| 0.0 | 0.1 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 0.0 | 1.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.6 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.1 | GO:0031720 | haptoglobin binding(GO:0031720) |
| 0.0 | 0.5 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.0 | 0.1 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.0 | 0.1 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 0.0 | 1.3 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.1 | GO:0030942 | endoplasmic reticulum signal peptide binding(GO:0030942) |
| 0.0 | 0.2 | GO:0003988 | acetyl-CoA C-acyltransferase activity(GO:0003988) |
| 0.0 | 1.1 | GO:0005080 | protein kinase C binding(GO:0005080) |
