Motif ID: Nfic_Nfib

Z-value: 1.561

Transcription factors associated with Nfic_Nfib:

Gene SymbolEntrez IDGene Name
Nfib ENSMUSG00000008575.11 Nfib
Nfic ENSMUSG00000055053.11 Nfic

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nficmm10_v2_chr10_-_81427114_814271870.521.0e-02Click!
Nfibmm10_v2_chr4_-_82505274_825053580.406.1e-02Click!


Activity profile for motif Nfic_Nfib.

activity profile for motif Nfic_Nfib


Sorted Z-values histogram for motif Nfic_Nfib

Sorted Z-values for motif Nfic_Nfib



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfic_Nfib

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_25470031 12.759 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr2_-_25469742 11.520 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr1_+_43730593 11.120 ENSMUST00000027217.8
 1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr2_+_32646586 6.839 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr11_+_78324200 6.462 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr6_+_17306335 5.678 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
 Cav1



caveolin 1, caveolae protein



chr3_+_94933041 5.604 ENSMUST00000090839.5
 Selenbp1
selenium binding protein 1
chr11_-_77894096 5.440 ENSMUST00000017597.4
 Pipox
pipecolic acid oxidase
chr3_-_85746266 4.852 ENSMUST00000118408.1
 Fam160a1
family with sequence similarity 160, member A1
chr11_+_115154139 4.548 ENSMUST00000021076.5
 Rab37
RAB37, member of RAS oncogene family
chr7_-_79386943 4.104 ENSMUST00000053718.8
ENSMUST00000179243.1
 Rlbp1

retinaldehyde binding protein 1

chr10_+_57784859 4.088 ENSMUST00000020024.5
 Fabp7
fatty acid binding protein 7, brain
chr7_-_97417730 3.997 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr13_-_97747373 3.690 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr3_-_107760221 3.506 ENSMUST00000153114.1
ENSMUST00000118593.1
ENSMUST00000120243.1
 Csf1


colony stimulating factor 1 (macrophage)


chr14_-_118052235 3.462 ENSMUST00000022725.2
 Dct
dopachrome tautomerase
chr11_+_109485606 3.371 ENSMUST00000106697.1
 Arsg
arylsulfatase G
chr6_+_135362931 3.346 ENSMUST00000032330.9
 Emp1
epithelial membrane protein 1
chr2_+_76650264 3.305 ENSMUST00000099986.2
 Dfnb59
deafness, autosomal recessive 59 (human)
chr16_+_90831113 3.293 ENSMUST00000037539.7
ENSMUST00000099543.3
 Eva1c

eva-1 homolog C (C. elegans)


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 167 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.9 24.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.4 11.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.9 8.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.9 7.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.4 6.9 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
2.3 6.8 GO:0003032 detection of oxygen(GO:0003032)
0.4 6.5 GO:0060134 prepulse inhibition(GO:0060134)
1.0 6.1 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
1.0 6.0 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
1.8 5.4 GO:0006553 lysine metabolic process(GO:0006553)
0.1 4.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 3.8 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
1.2 3.5 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.6 3.5 GO:0006570 tyrosine metabolic process(GO:0006570)
0.3 3.5 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 3.5 GO:0007601 visual perception(GO:0007601)
0.1 3.3 GO:0060325 face morphogenesis(GO:0060325)
0.5 3.2 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 2.9 GO:0032060 bleb assembly(GO:0032060)
0.0 2.8 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 19.9 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 14.6 GO:0005615 extracellular space(GO:0005615)
0.5 6.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 6.2 GO:0044297 cell body(GO:0044297)
0.9 6.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)
1.9 5.8 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 5.8 GO:0072562 blood microparticle(GO:0072562)
1.6 4.9 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
1.1 4.5 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 4.5 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 4.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
1.3 4.0 GO:0071953 elastic fiber(GO:0071953)
0.1 3.7 GO:0005844 polysome(GO:0005844)
1.2 3.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 3.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.3 GO:0005901 caveola(GO:0005901)
0.1 3.0 GO:0097546 ciliary base(GO:0097546)
0.0 2.9 GO:0042383 sarcolemma(GO:0042383)
0.1 2.7 GO:0005921 gap junction(GO:0005921)
0.1 2.7 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 111 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.1 24.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.5 8.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.6 8.4 GO:0008430 selenium binding(GO:0008430)
0.3 7.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 7.0 GO:0005178 integrin binding(GO:0005178)
1.4 6.9 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
2.3 6.8 GO:0005534 galactose binding(GO:0005534)
0.3 6.0 GO:0051787 misfolded protein binding(GO:0051787)
0.1 5.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 5.8 GO:0005504 fatty acid binding(GO:0005504)
1.4 5.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
1.2 4.9 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.1 4.8 GO:0008083 growth factor activity(GO:0008083)
0.1 4.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.7 4.1 GO:0019841 retinol binding(GO:0019841)
0.3 3.8 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 3.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.4 3.4 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 3.2 GO:0030246 carbohydrate binding(GO:0030246)
0.2 3.1 GO:0001223 transcription coactivator binding(GO:0001223)