Motif ID: Tfap2a
Z-value: 0.841
Transcription factors associated with Tfap2a:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Tfap2a | ENSMUSG00000021359.9 | Tfap2a |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tfap2a | mm10_v2_chr13_-_40733768_40733836 | 0.54 | 7.3e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.5 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
0.4 | 1.2 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
0.4 | 1.5 | GO:0033024 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) |
0.3 | 0.9 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.3 | 1.1 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.3 | 1.4 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
0.3 | 1.6 | GO:0098700 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700) |
0.3 | 0.8 | GO:0048211 | Golgi vesicle docking(GO:0048211) |
0.3 | 1.3 | GO:2000483 | negative regulation of interleukin-8 secretion(GO:2000483) |
0.2 | 1.1 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
0.2 | 0.8 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
0.2 | 0.8 | GO:0051012 | microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856) |
0.2 | 0.6 | GO:0048304 | positive regulation of isotype switching to IgG isotypes(GO:0048304) |
0.2 | 0.5 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627) |
0.1 | 1.0 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.1 | 0.7 | GO:0015867 | ATP transport(GO:0015867) |
0.1 | 0.4 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
0.1 | 0.5 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
0.1 | 0.6 | GO:0033762 | response to glucagon(GO:0033762) |
0.1 | 1.0 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
0.1 | 0.5 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
0.1 | 0.3 | GO:0045976 | cell proliferation in midbrain(GO:0033278) negative regulation of mitotic cell cycle, embryonic(GO:0045976) |
0.1 | 0.3 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) phosphatidylserine exposure on apoptotic cell surface(GO:0070782) |
0.1 | 0.3 | GO:0061198 | fungiform papilla formation(GO:0061198) |
0.1 | 0.3 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
0.1 | 0.3 | GO:0061535 | glutamate secretion, neurotransmission(GO:0061535) |
0.1 | 0.4 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
0.1 | 2.2 | GO:0032897 | negative regulation of viral transcription(GO:0032897) |
0.1 | 1.0 | GO:0075522 | IRES-dependent viral translational initiation(GO:0075522) |
0.1 | 0.6 | GO:0003065 | positive regulation of heart rate by epinephrine(GO:0003065) |
0.1 | 0.5 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
0.1 | 0.3 | GO:0016056 | photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) |
0.1 | 0.5 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.1 | 1.4 | GO:0070842 | aggresome assembly(GO:0070842) |
0.1 | 0.7 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
0.1 | 0.6 | GO:0060046 | regulation of acrosome reaction(GO:0060046) |
0.1 | 0.5 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
0.1 | 1.0 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.1 | 0.6 | GO:0071442 | positive regulation of histone H3-K14 acetylation(GO:0071442) |
0.1 | 0.4 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
0.1 | 0.6 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.1 | 2.1 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
0.1 | 0.3 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
0.1 | 0.4 | GO:0060017 | parathyroid gland development(GO:0060017) |
0.1 | 0.3 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
0.1 | 0.2 | GO:0030997 | regulation of centriole-centriole cohesion(GO:0030997) |
0.1 | 0.7 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
0.1 | 0.3 | GO:0010040 | response to iron(II) ion(GO:0010040) |
0.1 | 0.6 | GO:0032782 | bile acid secretion(GO:0032782) |
0.1 | 0.3 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.1 | 0.2 | GO:0003096 | renal sodium ion transport(GO:0003096) |
0.1 | 2.4 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
0.1 | 0.7 | GO:1903423 | positive regulation of synaptic vesicle recycling(GO:1903423) |
0.1 | 0.1 | GO:0060423 | foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) |
0.1 | 0.3 | GO:0006203 | dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061) |
0.1 | 0.2 | GO:0002765 | immune response-inhibiting signal transduction(GO:0002765) |
0.1 | 0.5 | GO:2001199 | negative regulation of dendritic cell differentiation(GO:2001199) |
0.1 | 1.2 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
0.1 | 0.2 | GO:0031860 | telomeric 3' overhang formation(GO:0031860) |
0.1 | 0.3 | GO:1904996 | diapedesis(GO:0050904) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
0.1 | 1.1 | GO:0071281 | cellular response to iron ion(GO:0071281) |
0.1 | 0.3 | GO:2000211 | regulation of glutamate metabolic process(GO:2000211) |
0.1 | 0.4 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
0.1 | 0.3 | GO:0021698 | cerebellar cortex structural organization(GO:0021698) |
0.1 | 0.3 | GO:0071034 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
0.1 | 0.4 | GO:0046501 | protoporphyrinogen IX metabolic process(GO:0046501) |
0.1 | 0.3 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
0.1 | 0.6 | GO:0045618 | positive regulation of keratinocyte differentiation(GO:0045618) |
0.1 | 0.3 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) |
0.1 | 0.6 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
0.1 | 0.6 | GO:0008063 | Toll signaling pathway(GO:0008063) |
0.1 | 0.2 | GO:0097500 | receptor localization to nonmotile primary cilium(GO:0097500) |
0.1 | 0.2 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) phosphate ion transmembrane transport(GO:0035435) |
0.1 | 0.7 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
0.1 | 0.3 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
0.1 | 0.5 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
0.1 | 0.4 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
0.1 | 1.3 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.1 | 0.2 | GO:0036216 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368) |
0.1 | 0.7 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) |
0.0 | 0.2 | GO:0097168 | mesenchymal stem cell proliferation(GO:0097168) |
0.0 | 0.1 | GO:0021649 | vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835) dorsal root ganglion development(GO:1990791) |
0.0 | 0.2 | GO:0016266 | O-glycan processing(GO:0016266) |
0.0 | 0.9 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.2 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
0.0 | 0.8 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
0.0 | 0.6 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
0.0 | 0.3 | GO:0006297 | nucleotide-excision repair, DNA gap filling(GO:0006297) |
0.0 | 0.1 | GO:0002901 | mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) regulation of interleukin-8 biosynthetic process(GO:0045414) |
0.0 | 0.3 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 0.4 | GO:0006020 | inositol metabolic process(GO:0006020) |
0.0 | 0.7 | GO:0050832 | defense response to fungus(GO:0050832) |
0.0 | 0.9 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
0.0 | 0.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.0 | 0.5 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
0.0 | 0.2 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.0 | 0.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
0.0 | 0.3 | GO:0071318 | cellular response to ATP(GO:0071318) |
0.0 | 0.4 | GO:0031268 | pseudopodium organization(GO:0031268) |
0.0 | 0.2 | GO:0034372 | very-low-density lipoprotein particle remodeling(GO:0034372) |
0.0 | 0.2 | GO:0006108 | malate metabolic process(GO:0006108) |
0.0 | 0.6 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.2 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
0.0 | 0.2 | GO:0042518 | negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) |
0.0 | 0.7 | GO:0035036 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) |
0.0 | 0.6 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
0.0 | 1.2 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.0 | 0.6 | GO:0008209 | androgen metabolic process(GO:0008209) |
0.0 | 0.0 | GO:0034370 | triglyceride-rich lipoprotein particle remodeling(GO:0034370) |
0.0 | 1.1 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
0.0 | 0.5 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
0.0 | 0.4 | GO:0031100 | organ regeneration(GO:0031100) |
0.0 | 0.5 | GO:0007340 | acrosome reaction(GO:0007340) |
0.0 | 0.2 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
0.0 | 0.1 | GO:0072429 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429) positive regulation of t-circle formation(GO:1904431) |
0.0 | 0.3 | GO:0019240 | citrulline biosynthetic process(GO:0019240) |
0.0 | 0.1 | GO:0051088 | PMA-inducible membrane protein ectodomain proteolysis(GO:0051088) |
0.0 | 0.6 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.0 | 0.2 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
0.0 | 0.1 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.0 | 0.1 | GO:0097459 | iron ion import into cell(GO:0097459) |
0.0 | 0.8 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
0.0 | 0.1 | GO:0019676 | ammonia assimilation cycle(GO:0019676) |
0.0 | 0.3 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
0.0 | 0.3 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
0.0 | 0.2 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.4 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.0 | 0.2 | GO:1903551 | regulation of extracellular exosome assembly(GO:1903551) |
0.0 | 0.5 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.0 | 0.2 | GO:0021559 | trigeminal nerve development(GO:0021559) |
0.0 | 0.1 | GO:2000195 | negative regulation of female gonad development(GO:2000195) |
0.0 | 0.1 | GO:1903025 | regulation of histone H3-K36 methylation(GO:0000414) regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
0.0 | 0.3 | GO:0060213 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
0.0 | 0.2 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
0.0 | 0.1 | GO:0046855 | phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855) |
0.0 | 0.1 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
0.0 | 0.2 | GO:0018065 | protein-cofactor linkage(GO:0018065) |
0.0 | 0.9 | GO:0070830 | bicellular tight junction assembly(GO:0070830) |
0.0 | 0.6 | GO:0045620 | negative regulation of lymphocyte differentiation(GO:0045620) |
0.0 | 0.8 | GO:2000171 | negative regulation of dendrite development(GO:2000171) |
0.0 | 0.1 | GO:0030397 | membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081) |
0.0 | 0.6 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
0.0 | 0.2 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
0.0 | 0.1 | GO:0051546 | keratinocyte migration(GO:0051546) |
0.0 | 0.3 | GO:0045672 | positive regulation of osteoclast differentiation(GO:0045672) |
0.0 | 0.1 | GO:1903363 | negative regulation of cellular protein catabolic process(GO:1903363) |
0.0 | 0.1 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.0 | 0.1 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
0.0 | 0.5 | GO:1903077 | negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376) |
0.0 | 0.6 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 0.3 | GO:0032060 | bleb assembly(GO:0032060) |
0.0 | 0.7 | GO:0006284 | base-excision repair(GO:0006284) |
0.0 | 0.1 | GO:0046469 | platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469) |
0.0 | 0.1 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
0.0 | 0.6 | GO:0036075 | endochondral ossification(GO:0001958) replacement ossification(GO:0036075) |
0.0 | 0.1 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
0.0 | 0.3 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
0.0 | 0.0 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180) |
0.0 | 0.2 | GO:1903333 | negative regulation of protein folding(GO:1903333) |
0.0 | 0.2 | GO:0002021 | response to dietary excess(GO:0002021) |
0.0 | 0.1 | GO:0051697 | protein delipidation(GO:0051697) |
0.0 | 0.1 | GO:0031053 | primary miRNA processing(GO:0031053) |
0.0 | 0.1 | GO:0032796 | negative regulation of vesicle fusion(GO:0031339) uropod organization(GO:0032796) |
0.0 | 0.2 | GO:0051382 | kinetochore assembly(GO:0051382) |
0.0 | 0.1 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
0.0 | 0.0 | GO:0021759 | globus pallidus development(GO:0021759) |
0.0 | 0.1 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
0.0 | 0.1 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
0.0 | 0.2 | GO:0045187 | regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187) |
0.0 | 0.1 | GO:0090220 | meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) |
0.0 | 0.7 | GO:0051384 | response to glucocorticoid(GO:0051384) |
0.0 | 0.1 | GO:0060049 | regulation of protein glycosylation(GO:0060049) |
0.0 | 0.1 | GO:0071346 | cellular response to interferon-gamma(GO:0071346) |
0.0 | 0.1 | GO:0001842 | neural fold formation(GO:0001842) |
0.0 | 0.0 | GO:0019401 | alditol biosynthetic process(GO:0019401) |
0.0 | 0.1 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
0.0 | 0.9 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 0.3 | GO:0007020 | microtubule nucleation(GO:0007020) |
0.0 | 0.0 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
0.0 | 0.2 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
0.0 | 0.0 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
0.0 | 0.3 | GO:1902236 | negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236) |
0.0 | 0.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
0.0 | 0.1 | GO:0019254 | carnitine metabolic process, CoA-linked(GO:0019254) |
0.0 | 0.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
0.0 | 0.1 | GO:0046514 | ceramide catabolic process(GO:0046514) |
0.0 | 0.7 | GO:0035304 | regulation of protein dephosphorylation(GO:0035304) |
0.0 | 0.1 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.0 | 0.3 | GO:0006270 | DNA replication initiation(GO:0006270) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.2 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
0.2 | 0.9 | GO:0000798 | nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991) |
0.2 | 0.8 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.1 | 0.4 | GO:0005940 | septin ring(GO:0005940) |
0.1 | 1.8 | GO:0043196 | varicosity(GO:0043196) |
0.1 | 1.5 | GO:0070938 | contractile ring(GO:0070938) |
0.1 | 0.8 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
0.1 | 1.1 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
0.1 | 1.6 | GO:0031045 | dense core granule(GO:0031045) |
0.1 | 0.5 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
0.1 | 0.3 | GO:0000801 | central element(GO:0000801) |
0.1 | 1.2 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.1 | 0.8 | GO:0032982 | myosin filament(GO:0032982) |
0.1 | 1.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.1 | 0.6 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.1 | 0.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
0.1 | 0.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
0.1 | 0.3 | GO:0032133 | chromosome passenger complex(GO:0032133) |
0.1 | 1.0 | GO:0000145 | exocyst(GO:0000145) |
0.1 | 0.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.1 | 0.8 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.1 | 0.5 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
0.1 | 0.3 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
0.1 | 1.6 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.0 | 0.1 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.0 | 0.3 | GO:0032584 | growth cone membrane(GO:0032584) |
0.0 | 0.9 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.0 | 1.2 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 1.3 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 0.3 | GO:0001940 | male pronucleus(GO:0001940) |
0.0 | 0.2 | GO:0030870 | Mre11 complex(GO:0030870) |
0.0 | 0.3 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
0.0 | 0.9 | GO:0034451 | centriolar satellite(GO:0034451) |
0.0 | 0.2 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
0.0 | 0.6 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
0.0 | 0.1 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
0.0 | 0.1 | GO:0070522 | ERCC4-ERCC1 complex(GO:0070522) |
0.0 | 0.2 | GO:0070578 | RISC-loading complex(GO:0070578) |
0.0 | 0.2 | GO:0071437 | invadopodium(GO:0071437) |
0.0 | 0.5 | GO:0000178 | exosome (RNase complex)(GO:0000178) |
0.0 | 0.1 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.0 | 0.8 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.0 | 0.1 | GO:0031417 | NatC complex(GO:0031417) |
0.0 | 0.2 | GO:0034464 | BBSome(GO:0034464) |
0.0 | 0.1 | GO:0071986 | Ragulator complex(GO:0071986) |
0.0 | 0.7 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.1 | GO:0042827 | platelet dense granule(GO:0042827) |
0.0 | 0.1 | GO:0000800 | lateral element(GO:0000800) |
0.0 | 0.6 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.3 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 0.3 | GO:0030061 | mitochondrial crista(GO:0030061) |
0.0 | 0.9 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.2 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
0.0 | 0.0 | GO:0002142 | stereocilia ankle link complex(GO:0002142) |
0.0 | 0.7 | GO:0016592 | mediator complex(GO:0016592) |
0.0 | 0.2 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
0.0 | 0.3 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
0.0 | 1.6 | GO:0016605 | PML body(GO:0016605) |
0.0 | 1.6 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 1.6 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 1.3 | GO:0060076 | excitatory synapse(GO:0060076) |
0.0 | 0.1 | GO:0033503 | HULC complex(GO:0033503) |
0.0 | 1.7 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
0.0 | 0.2 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
0.0 | 0.1 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.0 | 0.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
0.0 | 0.1 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
0.0 | 0.2 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
0.0 | 0.1 | GO:0036157 | outer dynein arm(GO:0036157) |
0.0 | 0.3 | GO:0043218 | compact myelin(GO:0043218) |
0.0 | 0.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
0.0 | 0.2 | GO:0031616 | spindle pole centrosome(GO:0031616) |
0.0 | 0.1 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.4 | GO:0032420 | stereocilium(GO:0032420) |
0.0 | 0.1 | GO:0005916 | fascia adherens(GO:0005916) |
0.0 | 0.2 | GO:0008305 | integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636) |
0.0 | 0.2 | GO:0035102 | PRC1 complex(GO:0035102) |
0.0 | 0.8 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 0.1 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
0.0 | 0.0 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 0.3 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.2 | GO:0031010 | ISWI-type complex(GO:0031010) |
0.0 | 0.1 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
0.0 | 0.7 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.0 | 0.2 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0008504 | monoamine transmembrane transporter activity(GO:0008504) |
0.4 | 1.1 | GO:0004998 | transferrin receptor activity(GO:0004998) |
0.3 | 1.5 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
0.2 | 1.1 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.2 | 0.9 | GO:0036033 | mediator complex binding(GO:0036033) |
0.2 | 0.6 | GO:0019966 | interleukin-1 binding(GO:0019966) |
0.2 | 0.8 | GO:0004515 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
0.2 | 0.2 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
0.2 | 0.7 | GO:0005347 | ATP transmembrane transporter activity(GO:0005347) |
0.1 | 0.6 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.1 | 0.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.1 | 0.5 | GO:0050347 | trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347) |
0.1 | 0.4 | GO:0030350 | iron-responsive element binding(GO:0030350) |
0.1 | 1.3 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 0.5 | GO:0097016 | L27 domain binding(GO:0097016) |
0.1 | 0.3 | GO:0034597 | phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) |
0.1 | 0.3 | GO:0009881 | photoreceptor activity(GO:0009881) |
0.1 | 0.7 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.1 | 0.9 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.1 | 1.1 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
0.1 | 0.5 | GO:0097001 | sphingolipid transporter activity(GO:0046624) ceramide binding(GO:0097001) |
0.1 | 2.1 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
0.1 | 0.8 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.1 | 0.3 | GO:0035851 | histone deacetylase activity (H4-K16 specific)(GO:0034739) Krueppel-associated box domain binding(GO:0035851) |
0.1 | 0.4 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
0.1 | 0.2 | GO:0004471 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) |
0.1 | 0.6 | GO:0005004 | GPI-linked ephrin receptor activity(GO:0005004) |
0.1 | 0.5 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
0.1 | 0.3 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
0.1 | 0.2 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
0.1 | 1.3 | GO:0005044 | scavenger receptor activity(GO:0005044) |
0.1 | 1.5 | GO:0043274 | phospholipase binding(GO:0043274) |
0.1 | 0.2 | GO:0042015 | interleukin-20 binding(GO:0042015) |
0.1 | 0.4 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
0.1 | 0.5 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.1 | 0.2 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.1 | 1.4 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.1 | 0.5 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.1 | 0.5 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.1 | 0.3 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.1 | 0.8 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
0.0 | 0.1 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
0.0 | 0.3 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.0 | 0.4 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
0.0 | 0.8 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
0.0 | 0.3 | GO:0035174 | histone serine kinase activity(GO:0035174) |
0.0 | 0.2 | GO:0052833 | inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834) |
0.0 | 0.7 | GO:0000146 | microfilament motor activity(GO:0000146) |
0.0 | 0.2 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
0.0 | 0.5 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
0.0 | 0.3 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
0.0 | 0.3 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
0.0 | 0.2 | GO:0023029 | peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980) |
0.0 | 0.3 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
0.0 | 0.2 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.0 | 0.3 | GO:0046790 | virion binding(GO:0046790) |
0.0 | 0.4 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.0 | 0.9 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 0.3 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
0.0 | 1.9 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.0 | 0.4 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.0 | 0.1 | GO:0042731 | PH domain binding(GO:0042731) |
0.0 | 0.1 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
0.0 | 0.5 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.0 | 2.2 | GO:0035064 | methylated histone binding(GO:0035064) |
0.0 | 0.1 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 0.7 | GO:0070410 | co-SMAD binding(GO:0070410) |
0.0 | 0.6 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
0.0 | 0.2 | GO:0016004 | phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229) |
0.0 | 0.7 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.3 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
0.0 | 0.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.2 | GO:0034452 | dynactin binding(GO:0034452) |
0.0 | 0.9 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.0 | 0.3 | GO:0032554 | purine deoxyribonucleotide binding(GO:0032554) |
0.0 | 0.1 | GO:0015410 | manganese-transporting ATPase activity(GO:0015410) |
0.0 | 0.2 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 0.3 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
0.0 | 0.2 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
0.0 | 0.9 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
0.0 | 1.2 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.1 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
0.0 | 0.1 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
0.0 | 0.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.0 | 0.3 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
0.0 | 1.2 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.3 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
0.0 | 0.1 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.0 | 0.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.2 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
0.0 | 2.0 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 0.2 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.0 | 0.6 | GO:0050681 | androgen receptor binding(GO:0050681) |
0.0 | 0.1 | GO:0003896 | DNA primase activity(GO:0003896) |
0.0 | 0.4 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 0.1 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.0 | 0.2 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.0 | 0.1 | GO:0043842 | Kdo transferase activity(GO:0043842) |
0.0 | 0.1 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
0.0 | 0.1 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.0 | 0.3 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
0.0 | 0.1 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
0.0 | 1.5 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 0.2 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.0 | 0.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
0.0 | 0.2 | GO:0035198 | miRNA binding(GO:0035198) |
0.0 | 0.1 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) |
0.0 | 0.0 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
0.0 | 0.6 | GO:0035326 | enhancer binding(GO:0035326) |
0.0 | 0.8 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 4.0 | GO:0043774 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738) |
0.0 | 0.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.1 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
0.0 | 0.2 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.1 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 0.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.1 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 0.0 | GO:0008521 | acetyl-CoA transporter activity(GO:0008521) |
0.0 | 0.0 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
0.0 | 0.7 | GO:0005518 | collagen binding(GO:0005518) |
0.0 | 0.3 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 0.2 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
0.0 | 0.1 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.0 | 0.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 0.6 | GO:0035591 | signaling adaptor activity(GO:0035591) |
0.0 | 0.2 | GO:0032452 | histone demethylase activity(GO:0032452) |
0.0 | 0.1 | GO:1990829 | C-rich single-stranded DNA binding(GO:1990829) |
0.0 | 0.1 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |