Motif ID: Pax7

Z-value: 0.474


Transcription factors associated with Pax7:

Gene SymbolEntrez IDGene Name
Pax7 ENSMUSG00000028736.7 Pax7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Pax7mm10_v2_chr4_-_139833524_139833535-0.291.8e-01Click!


Activity profile for motif Pax7.

activity profile for motif Pax7


Sorted Z-values histogram for motif Pax7

Sorted Z-values for motif Pax7



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_67113909 2.527 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr15_-_64922290 1.156 ENSMUST00000023007.5
 Adcy8
adenylate cyclase 8
chr10_+_85386813 1.126 ENSMUST00000105307.1
ENSMUST00000020231.3
 Btbd11

BTB (POZ) domain containing 11

chr4_+_102589687 0.548 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chr13_+_67833235 0.525 ENSMUST00000060609.7
 Gm10037
predicted gene 10037
chr15_-_37459327 0.500 ENSMUST00000119730.1
ENSMUST00000120746.1
 Ncald

neurocalcin delta

chr3_+_55461758 0.472 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chr5_+_26817357 0.434 ENSMUST00000071500.6
 Dpp6
dipeptidylpeptidase 6
chr10_-_62379852 0.427 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
 Hk1



hexokinase 1



chr5_-_138170992 0.412 ENSMUST00000139983.1
 Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_-_33718789 0.392 ENSMUST00000130532.1
 9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr9_-_71163224 0.353 ENSMUST00000074465.2
 Aqp9
aquaporin 9
chr3_+_96268654 0.351 ENSMUST00000098843.2
 Hist2h3b
histone cluster 2, H3b
chr4_+_108719649 0.317 ENSMUST00000178992.1
 3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr13_-_23934156 0.303 ENSMUST00000052776.2
 Hist1h2ba
histone cluster 1, H2ba
chr8_+_107031218 0.301 ENSMUST00000034388.9
 Vps4a
vacuolar protein sorting 4a (yeast)
chr19_+_41933464 0.285 ENSMUST00000026154.7
 Zdhhc16
zinc finger, DHHC domain containing 16
chr4_-_14621669 0.276 ENSMUST00000143105.1
 Slc26a7
solute carrier family 26, member 7
chr2_+_125136692 0.266 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr4_-_14621805 0.246 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr13_+_22043189 0.244 ENSMUST00000110452.1
 Hist1h2bj
histone cluster 1, H2bj
chr12_+_117843489 0.234 ENSMUST00000021592.9
 Cdca7l
cell division cycle associated 7 like
chr9_-_20959785 0.233 ENSMUST00000177754.1
 Dnmt1
DNA methyltransferase (cytosine-5) 1
chr5_-_92348871 0.209 ENSMUST00000038816.6
ENSMUST00000118006.1
 Cxcl10

chemokine (C-X-C motif) ligand 10

chr8_-_34965631 0.199 ENSMUST00000033929.4
 Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr13_-_22042949 0.199 ENSMUST00000091741.4
 Hist1h2ag
histone cluster 1, H2ag
chr4_-_14621494 0.193 ENSMUST00000149633.1
 Slc26a7
solute carrier family 26, member 7
chr13_+_23533869 0.192 ENSMUST00000073261.2
 Hist1h2af
histone cluster 1, H2af
chr7_+_19228334 0.188 ENSMUST00000063976.8
 Opa3
optic atrophy 3
chr13_-_102906046 0.182 ENSMUST00000171791.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr15_-_79774408 0.179 ENSMUST00000023055.6
 Dnal4
dynein, axonemal, light chain 4
chr15_-_79774383 0.176 ENSMUST00000069877.5
 Dnal4
dynein, axonemal, light chain 4
chr18_+_38993126 0.175 ENSMUST00000097593.2
 Arhgap26
Rho GTPase activating protein 26
chr7_+_127233227 0.172 ENSMUST00000056232.6
 Zfp553
zinc finger protein 553
chr1_+_72284367 0.152 ENSMUST00000027380.5
ENSMUST00000141783.1
 Tmem169

transmembrane protein 169

chr11_-_115276973 0.143 ENSMUST00000021078.2
 Fdxr
ferredoxin reductase
chr4_+_136286061 0.140 ENSMUST00000069195.4
ENSMUST00000130658.1
 Zfp46

zinc finger protein 46

chr9_+_21955747 0.134 ENSMUST00000053583.5
 Swsap1
SWIM type zinc finger 7 associated protein 1
chr13_-_102905740 0.121 ENSMUST00000167462.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr8_-_61902669 0.114 ENSMUST00000121785.1
ENSMUST00000034057.7
 Palld

palladin, cytoskeletal associated protein

chr10_+_128083273 0.102 ENSMUST00000026459.5
 Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr2_+_65620829 0.095 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr17_+_35517100 0.088 ENSMUST00000164242.2
ENSMUST00000045956.7
 Cchcr1

coiled-coil alpha-helical rod protein 1

chr11_+_116843278 0.083 ENSMUST00000106370.3
 Mettl23
methyltransferase like 23
chr6_+_145934113 0.078 ENSMUST00000032383.7
 Sspn
sarcospan
chr19_+_8802486 0.065 ENSMUST00000172175.1
 Zbtb3
zinc finger and BTB domain containing 3
chr14_+_55560010 0.062 ENSMUST00000147981.1
ENSMUST00000133256.1
 Dcaf11

DDB1 and CUL4 associated factor 11

chr11_-_87359011 0.056 ENSMUST00000055438.4
 Ppm1e
protein phosphatase 1E (PP2C domain containing)
chr19_-_15924560 0.054 ENSMUST00000162053.1
 Psat1
phosphoserine aminotransferase 1
chr13_+_55445301 0.051 ENSMUST00000001115.8
ENSMUST00000099482.3
 Grk6

G protein-coupled receptor kinase 6

chr2_+_32727682 0.051 ENSMUST00000113242.2
 Sh2d3c
SH2 domain containing 3C
chr9_+_102720287 0.045 ENSMUST00000130602.1
 Amotl2
angiomotin-like 2
chr16_+_58408443 0.042 ENSMUST00000046663.7
 Dcbld2
discoidin, CUB and LCCL domain containing 2
chr7_-_19715395 0.040 ENSMUST00000032555.9
ENSMUST00000093552.5
 Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr19_-_41933276 0.039 ENSMUST00000075280.4
ENSMUST00000112123.2
 Exosc1

exosome component 1

chr14_+_55559993 0.038 ENSMUST00000117236.1
 Dcaf11
DDB1 and CUL4 associated factor 11
chr19_-_15924928 0.027 ENSMUST00000025542.3
 Psat1
phosphoserine aminotransferase 1
chr12_+_72441933 0.011 ENSMUST00000161284.1
 Lrrc9
leucine rich repeat containing 9
chr14_+_76110885 0.009 ENSMUST00000022586.1
 Nufip1
nuclear fragile X mental retardation protein interacting protein 1
chr18_-_77047282 0.008 ENSMUST00000154665.1
ENSMUST00000026486.6
ENSMUST00000123650.1
ENSMUST00000126153.1
 Katnal2



katanin p60 subunit A-like 2



chrX_+_9885622 0.003 ENSMUST00000067529.2
ENSMUST00000086165.3
 Sytl5

synaptotagmin-like 5


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.7 GO:0019532 oxalate transport(GO:0019532)
0.1 0.3 GO:0009838 abscission(GO:0009838) positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:0010359 regulation of anion channel activity(GO:0010359)
0.1 0.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.2 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.1 0.3 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.4 GO:0015791 polyol transport(GO:0015791) urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 1.2 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 1.1 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.4 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.0 0.5 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 1.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.4 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0015265 urea channel activity(GO:0015265)
0.0 0.2 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)