Motif ID: Zkscan3

Z-value: 0.377


Transcription factors associated with Zkscan3:

Gene SymbolEntrez IDGene Name
Zkscan3 ENSMUSG00000021327.12 Zkscan3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Zkscan3mm10_v2_chr13_-_21402688_21402755-0.096.8e-01Click!


Activity profile for motif Zkscan3.

activity profile for motif Zkscan3


Sorted Z-values histogram for motif Zkscan3

Sorted Z-values for motif Zkscan3



Network of associatons between targets according to the STRING database.



First level regulatory network of Zkscan3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_75422586 0.474 ENSMUST00000138661.1
ENSMUST00000000769.7
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr13_-_100786402 0.450 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
 Ccnb1


cyclin B1


chr2_+_104095796 0.393 ENSMUST00000040423.5
ENSMUST00000168176.1
 Cd59a

CD59a antigen

chr4_+_156026120 0.344 ENSMUST00000103173.3
 Tnfrsf18
tumor necrosis factor receptor superfamily, member 18
chr5_+_24985840 0.321 ENSMUST00000075081.6
 1500035N22Rik
RIKEN cDNA 1500035N22 gene
chr3_+_146500071 0.283 ENSMUST00000119130.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr2_+_104069819 0.272 ENSMUST00000111131.2
ENSMUST00000111132.1
ENSMUST00000129749.1
 Cd59b


CD59b antigen


chr14_+_51893610 0.236 ENSMUST00000047726.5
ENSMUST00000161888.1
 Slc39a2

solute carrier family 39 (zinc transporter), member 2

chr3_+_79629074 0.235 ENSMUST00000029388.8
 4930579G24Rik
RIKEN cDNA 4930579G24 gene
chr2_-_66634952 0.229 ENSMUST00000100064.2
ENSMUST00000100063.2
 Scn9a

sodium channel, voltage-gated, type IX, alpha

chrX_-_75874536 0.205 ENSMUST00000033547.7
 Pls3
plastin 3 (T-isoform)
chr12_+_69724939 0.189 ENSMUST00000021372.5
 Atp5s
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s
chr3_+_146499850 0.185 ENSMUST00000118280.1
 Gng5
guanine nucleotide binding protein (G protein), gamma 5
chr1_+_37997975 0.182 ENSMUST00000027252.7
 Eif5b
eukaryotic translation initiation factor 5B
chr15_-_3979432 0.181 ENSMUST00000022791.8
 Fbxo4
F-box protein 4
chr1_+_180942452 0.179 ENSMUST00000027800.8
 Tmem63a
transmembrane protein 63a
chrX_-_17571563 0.173 ENSMUST00000177213.1
 Fundc1
FUN14 domain containing 1
chrX_-_17572241 0.171 ENSMUST00000176638.1
ENSMUST00000026016.6
 Fundc1

FUN14 domain containing 1

chr8_+_94810446 0.161 ENSMUST00000034232.1
 Ccl17
chemokine (C-C motif) ligand 17
chr13_-_19395728 0.159 ENSMUST00000039694.7
 Stard3nl
STARD3 N-terminal like
chr5_-_88675613 0.158 ENSMUST00000113234.1
ENSMUST00000153565.1
 Grsf1

G-rich RNA sequence binding factor 1

chr12_+_76533540 0.138 ENSMUST00000075249.4
 Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr8_+_33732237 0.137 ENSMUST00000171010.1
 Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr8_+_70616816 0.134 ENSMUST00000052437.3
 Lrrc25
leucine rich repeat containing 25
chr1_+_135232045 0.129 ENSMUST00000110798.3
 Gm4204
predicted gene 4204
chr6_+_125552948 0.119 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr7_+_101896340 0.118 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
 Anapc15


anaphase prompoting complex C subunit 15


chr4_+_156026304 0.118 ENSMUST00000040274.7
ENSMUST00000122001.1
 Tnfrsf18

tumor necrosis factor receptor superfamily, member 18

chr10_-_33951190 0.113 ENSMUST00000048222.4
 Zufsp
zinc finger with UFM1-specific peptidase domain
chr4_+_15957923 0.101 ENSMUST00000029879.8
ENSMUST00000149069.1
 Nbn

nibrin

chr11_-_102365111 0.097 ENSMUST00000006749.9
 Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr2_+_121171155 0.096 ENSMUST00000110658.1
 Tubgcp4
tubulin, gamma complex associated protein 4
chr13_-_38658991 0.094 ENSMUST00000001757.7
 Eef1e1
eukaryotic translation elongation factor 1 epsilon 1
chr11_+_35769462 0.092 ENSMUST00000018990.7
 Pank3
pantothenate kinase 3
chr3_-_95687846 0.089 ENSMUST00000015994.3
ENSMUST00000148854.1
ENSMUST00000117782.1
 Adamtsl4


ADAMTS-like 4


chr7_-_81345189 0.087 ENSMUST00000080813.4
 Rps17
ribosomal protein S17
chr4_+_63544747 0.086 ENSMUST00000035301.6
 Atp6v1g1
ATPase, H+ transporting, lysosomal V1 subunit G1
chr8_+_31091593 0.083 ENSMUST00000161713.1
 Dusp26
dual specificity phosphatase 26 (putative)
chr7_+_126759601 0.082 ENSMUST00000050201.4
ENSMUST00000057669.9
 Mapk3

mitogen-activated protein kinase 3

chr12_+_32954179 0.079 ENSMUST00000020885.6
 Sypl
synaptophysin-like protein
chr12_-_69724830 0.077 ENSMUST00000021370.8
 L2hgdh
L-2-hydroxyglutarate dehydrogenase
chr2_-_30194112 0.071 ENSMUST00000113659.1
ENSMUST00000113660.1
 Ccbl1

cysteine conjugate-beta lyase 1

chr14_+_57424054 0.067 ENSMUST00000122063.1
 Ift88
intraflagellar transport 88
chr11_-_100650693 0.062 ENSMUST00000103119.3
 Zfp385c
zinc finger protein 385C
chr16_-_16359016 0.061 ENSMUST00000023477.7
ENSMUST00000096229.3
ENSMUST00000115749.1
 Dnm1l


dynamin 1-like


chr17_+_46110982 0.061 ENSMUST00000024763.3
ENSMUST00000123646.1
 Mrps18a

mitochondrial ribosomal protein S18A

chr7_-_127020321 0.059 ENSMUST00000032918.2
 Pagr1a
PAXIP1 associated glutamate rich protein 1A
chr2_+_156613664 0.057 ENSMUST00000169464.2
ENSMUST00000109567.3
 Dlgap4

discs, large homolog-associated protein 4 (Drosophila)

chr18_+_61105844 0.056 ENSMUST00000115268.3
 Csf1r
colony stimulating factor 1 receptor
chr9_+_114688782 0.053 ENSMUST00000047404.6
 Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
chr2_+_121295437 0.052 ENSMUST00000110639.1
 Map1a
microtubule-associated protein 1 A
chr4_+_139192899 0.043 ENSMUST00000102508.3
ENSMUST00000131912.1
ENSMUST00000102507.3
 Capzb


capping protein (actin filament) muscle Z-line, beta


chr1_+_58795371 0.041 ENSMUST00000027189.8
 Casp8
caspase 8
chr2_+_31670714 0.041 ENSMUST00000038474.7
ENSMUST00000137156.1
 Exosc2

exosome component 2

chr3_-_63929376 0.037 ENSMUST00000061706.6
 E130311K13Rik
RIKEN cDNA E130311K13 gene
chr1_+_132298606 0.036 ENSMUST00000046071.4
 Klhdc8a
kelch domain containing 8A
chr2_+_121171204 0.032 ENSMUST00000039541.5
ENSMUST00000110657.1
 Tubgcp4

tubulin, gamma complex associated protein 4

chr6_-_122856151 0.029 ENSMUST00000042081.8
 C3ar1
complement component 3a receptor 1
chr8_+_71396853 0.029 ENSMUST00000002473.8
 Babam1
BRISC and BRCA1 A complex member 1
chr13_+_104109737 0.027 ENSMUST00000044385.7
 Sgtb
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr1_-_173333503 0.018 ENSMUST00000038227.4
 Darc
Duffy blood group, chemokine receptor
chr13_+_44730726 0.016 ENSMUST00000173704.1
ENSMUST00000044608.7
ENSMUST00000173367.1
 Jarid2


jumonji, AT rich interactive domain 2


chr2_+_32646586 0.014 ENSMUST00000009705.7
ENSMUST00000167841.1
 Eng

endoglin

chr8_+_106893616 0.012 ENSMUST00000047629.5
 Cirh1a
cirrhosis, autosomal recessive 1A (human)
chr17_-_35673517 0.011 ENSMUST00000162266.1
ENSMUST00000160734.1
ENSMUST00000159852.1
ENSMUST00000160039.1
 Gtf2h4



general transcription factor II H, polypeptide 4



chr10_+_89744988 0.008 ENSMUST00000020112.5
 Uhrf1bp1l
UHRF1 (ICBP90) binding protein 1-like
chr4_-_155863362 0.004 ENSMUST00000030949.3
 Tas1r3
taste receptor, type 1, member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.1 0.7 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.5 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0 0.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.0 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033) CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.5 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.1 GO:0005816 spindle pole body(GO:0005816)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.2 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005113 patched binding(GO:0005113)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.0 GO:0035877 death effector domain binding(GO:0035877)