Motif ID: Gata2_Gata1

Z-value: 0.544

Transcription factors associated with Gata2_Gata1:

Gene SymbolEntrez IDGene Name
Gata1 ENSMUSG00000031162.8 Gata1
Gata2 ENSMUSG00000015053.8 Gata2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata2mm10_v2_chr6_+_88198656_881986750.692.6e-04Click!
Gata1mm10_v2_chrX_-_7967817_79679100.029.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gata2_Gata1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_84701430 3.038 ENSMUST00000037165.4
Lyl1
lymphoblastomic leukemia 1
chr3_+_135825788 2.044 ENSMUST00000167390.1
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr16_-_95459245 1.888 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr16_+_45093611 1.651 ENSMUST00000099498.2
Ccdc80
coiled-coil domain containing 80
chr16_+_45094036 1.580 ENSMUST00000061050.5
Ccdc80
coiled-coil domain containing 80
chrX_-_107403295 1.433 ENSMUST00000033591.5
Itm2a
integral membrane protein 2A
chr6_+_30541582 1.431 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr7_-_4522427 1.372 ENSMUST00000098859.3
Tnni3
troponin I, cardiac 3
chr1_-_162866502 1.297 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chrX_+_73757069 1.287 ENSMUST00000002079.6
Plxnb3
plexin B3
chr6_+_125552948 1.226 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chr3_+_135826075 1.140 ENSMUST00000029810.5
Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr2_+_70474923 1.108 ENSMUST00000100043.2
Sp5
trans-acting transcription factor 5
chr13_+_38345716 1.050 ENSMUST00000171970.1
Bmp6
bone morphogenetic protein 6
chr13_-_116309639 1.030 ENSMUST00000036060.6
Isl1
ISL1 transcription factor, LIM/homeodomain
chr9_-_32541589 0.982 ENSMUST00000016231.7
Fli1
Friend leukemia integration 1
chr17_-_45593626 0.958 ENSMUST00000163905.1
ENSMUST00000167692.1
Slc29a1

solute carrier family 29 (nucleoside transporters), member 1

chr7_+_28833975 0.911 ENSMUST00000066723.8
Lgals4
lectin, galactose binding, soluble 4
chr3_-_88000350 0.909 ENSMUST00000090971.5
Bcan
brevican
chr7_-_4522794 0.846 ENSMUST00000140424.1
Tnni3
troponin I, cardiac 3
chr3_+_7366598 0.839 ENSMUST00000028999.6
Pkia
protein kinase inhibitor, alpha
chrX_+_150547375 0.791 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr3_-_20242173 0.788 ENSMUST00000001921.1
Cpa3
carboxypeptidase A3, mast cell
chr1_+_172341197 0.782 ENSMUST00000056136.3
Kcnj10
potassium inwardly-rectifying channel, subfamily J, member 10
chr11_+_90030295 0.763 ENSMUST00000092788.3
Tmem100
transmembrane protein 100
chr4_+_41760454 0.715 ENSMUST00000108040.1
Il11ra1
interleukin 11 receptor, alpha chain 1
chr1_-_173333503 0.656 ENSMUST00000038227.4
Darc
Duffy blood group, chemokine receptor
chr2_-_77170592 0.609 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr5_-_121836852 0.604 ENSMUST00000086310.1
Sh2b3
SH2B adaptor protein 3
chr7_-_139582790 0.602 ENSMUST00000106095.2
Nkx6-2
NK6 homeobox 2
chr16_-_64786321 0.588 ENSMUST00000052588.4
Zfp654
zinc finger protein 654
chr4_-_32923455 0.577 ENSMUST00000035719.4
ENSMUST00000084749.1
Ankrd6

ankyrin repeat domain 6

chr6_+_17306335 0.557 ENSMUST00000007799.6
ENSMUST00000115456.1
ENSMUST00000115455.2
ENSMUST00000130505.1
Cav1



caveolin 1, caveolae protein



chr14_-_52279238 0.557 ENSMUST00000167116.1
ENSMUST00000100631.4
Rab2b

RAB2B, member RAS oncogene family

chr1_+_75507077 0.557 ENSMUST00000037330.4
Inha
inhibin alpha
chr10_-_115185015 0.550 ENSMUST00000006949.8
Tph2
tryptophan hydroxylase 2
chr7_+_110627650 0.542 ENSMUST00000033054.8
Adm
adrenomedullin
chr5_-_121836810 0.533 ENSMUST00000118580.1
ENSMUST00000040308.7
Sh2b3

SH2B adaptor protein 3

chr2_+_62046623 0.532 ENSMUST00000112480.2
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr19_+_38264761 0.526 ENSMUST00000087252.5
Lgi1
leucine-rich repeat LGI family, member 1
chr1_+_45311538 0.525 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr2_+_72476159 0.520 ENSMUST00000102691.4
Cdca7
cell division cycle associated 7
chr2_-_33086366 0.520 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr2_-_33087169 0.504 ENSMUST00000102810.3
Garnl3
GTPase activating RANGAP domain-like 3
chr4_+_11579647 0.497 ENSMUST00000180239.1
Fsbp
fibrinogen silencer binding protein
chr1_-_14310198 0.490 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chr4_-_138326234 0.469 ENSMUST00000105817.3
ENSMUST00000030536.6
Pink1

PTEN induced putative kinase 1

chr2_-_36104060 0.461 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr2_+_26583858 0.459 ENSMUST00000100290.5
ENSMUST00000102907.5
Egfl7

EGF-like domain 7

chr5_+_24364804 0.439 ENSMUST00000030834.4
ENSMUST00000115090.1
Nos3

nitric oxide synthase 3, endothelial cell

chr10_-_83648631 0.420 ENSMUST00000146876.2
ENSMUST00000176294.1
Appl2

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2

chr14_+_55560904 0.407 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr14_+_13284774 0.402 ENSMUST00000070323.5
Synpr
synaptoporin
chr14_+_55561060 0.401 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr16_-_44016387 0.385 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chr7_-_80403315 0.382 ENSMUST00000147150.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr1_+_165788681 0.382 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
Cd247



CD247 antigen



chr6_+_17743582 0.380 ENSMUST00000000674.6
ENSMUST00000077080.2
St7

suppression of tumorigenicity 7

chr4_-_14621805 0.371 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr11_-_94242701 0.358 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr2_-_20968881 0.350 ENSMUST00000114594.1
Arhgap21
Rho GTPase activating protein 21
chr5_+_64812336 0.349 ENSMUST00000166409.1
Klf3
Kruppel-like factor 3 (basic)
chrX_+_10485121 0.349 ENSMUST00000076354.6
ENSMUST00000115526.1
Tspan7

tetraspanin 7

chr2_+_69670100 0.336 ENSMUST00000100050.3
Klhl41
kelch-like 41
chrX_-_60403947 0.336 ENSMUST00000033480.6
ENSMUST00000101527.2
Atp11c

ATPase, class VI, type 11C

chr5_-_125294107 0.335 ENSMUST00000127148.1
Scarb1
scavenger receptor class B, member 1
chrX_+_99975570 0.328 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr6_+_15185203 0.317 ENSMUST00000154448.1
Foxp2
forkhead box P2
chr1_+_165788746 0.313 ENSMUST00000161559.2
Cd247
CD247 antigen
chr2_+_62046580 0.303 ENSMUST00000054484.8
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr7_+_119900099 0.295 ENSMUST00000106516.1
Lyrm1
LYR motif containing 1
chr9_-_44342332 0.291 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chrX_+_166238901 0.291 ENSMUST00000112235.1
Gpm6b
glycoprotein m6b
chr12_-_25096080 0.287 ENSMUST00000020974.6
Id2
inhibitor of DNA binding 2
chr4_-_59438633 0.272 ENSMUST00000040166.7
ENSMUST00000107544.1
Susd1

sushi domain containing 1

chr2_+_112284561 0.264 ENSMUST00000053666.7
Slc12a6
solute carrier family 12, member 6
chr3_+_106113229 0.262 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr3_-_63851251 0.251 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1


phospholipase C, eta 1


chr2_+_72476225 0.244 ENSMUST00000157019.1
Cdca7
cell division cycle associated 7
chr14_-_55560340 0.235 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr11_-_102469839 0.233 ENSMUST00000103086.3
Itga2b
integrin alpha 2b
chr11_+_87760533 0.232 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr13_+_56702983 0.209 ENSMUST00000069557.7
ENSMUST00000109876.1
Smad5

SMAD family member 5

chr8_+_84908731 0.205 ENSMUST00000134569.1
Dnase2a
deoxyribonuclease II alpha
chr14_-_64455903 0.203 ENSMUST00000067927.7
Msra
methionine sulfoxide reductase A
chr1_-_82586781 0.202 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr19_+_58670358 0.200 ENSMUST00000057270.7
Pnlip
pancreatic lipase
chr8_+_84908560 0.194 ENSMUST00000003910.6
ENSMUST00000109744.1
Dnase2a

deoxyribonuclease II alpha

chr13_-_18031616 0.194 ENSMUST00000099736.2
Vdac3-ps1
voltage-dependent anion channel 3, pseudogene 1
chr17_-_84682932 0.192 ENSMUST00000066175.3
Abcg5
ATP-binding cassette, sub-family G (WHITE), member 5
chr8_+_84901928 0.190 ENSMUST00000067060.7
Klf1
Kruppel-like factor 1 (erythroid)
chr6_+_17463927 0.184 ENSMUST00000115442.1
Met
met proto-oncogene
chr6_-_122609964 0.179 ENSMUST00000032211.4
Gdf3
growth differentiation factor 3
chr14_+_55560480 0.178 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr16_+_43503607 0.175 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr7_-_100662315 0.169 ENSMUST00000151123.1
ENSMUST00000107047.2
Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chr6_-_136941887 0.166 ENSMUST00000111891.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr13_+_98263242 0.165 ENSMUST00000022164.8
ENSMUST00000150352.1
Ankra2

ankyrin repeat, family A (RFXANK-like), 2

chr3_-_154330543 0.165 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr4_-_46404224 0.159 ENSMUST00000107764.2
Hemgn
hemogen
chr5_+_42067960 0.153 ENSMUST00000087332.4
Gm16223
predicted gene 16223
chrM_+_14138 0.146 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr9_-_77251829 0.145 ENSMUST00000184322.1
ENSMUST00000184316.1
Mlip

muscular LMNA-interacting protein

chr11_+_70639118 0.135 ENSMUST00000055184.6
ENSMUST00000108551.2
Gp1ba

glycoprotein 1b, alpha polypeptide

chr3_-_59262825 0.134 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr11_-_53707269 0.134 ENSMUST00000124352.1
ENSMUST00000020649.7
Rad50

RAD50 homolog (S. cerevisiae)

chr8_+_84908680 0.127 ENSMUST00000145292.1
Dnase2a
deoxyribonuclease II alpha
chr18_+_7869159 0.124 ENSMUST00000170932.1
ENSMUST00000167020.1
Wac

WW domain containing adaptor with coiled-coil

chr1_+_75549581 0.120 ENSMUST00000154101.1
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr13_-_91388079 0.119 ENSMUST00000181054.1
A830009L08Rik
RIKEN cDNA A830009L08 gene
chrX_-_134111852 0.117 ENSMUST00000033610.6
Nox1
NADPH oxidase 1
chr6_+_17306415 0.115 ENSMUST00000150901.1
Cav1
caveolin 1, caveolae protein
chr18_+_76059458 0.115 ENSMUST00000167921.1
Zbtb7c
zinc finger and BTB domain containing 7C
chr6_-_122856151 0.111 ENSMUST00000042081.8
C3ar1
complement component 3a receptor 1
chrM_+_5319 0.104 ENSMUST00000082402.1
mt-Co1
mitochondrially encoded cytochrome c oxidase I
chr10_+_5593718 0.097 ENSMUST00000051809.8
Myct1
myc target 1
chrX_-_18461371 0.095 ENSMUST00000044188.4
4930578C19Rik
RIKEN cDNA 4930578C19 gene
chr10_-_14718191 0.089 ENSMUST00000020016.4
Gje1
gap junction protein, epsilon 1
chr6_-_136941494 0.087 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr10_+_116177351 0.078 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr9_-_44713196 0.077 ENSMUST00000144251.1
ENSMUST00000156918.1
Phldb1

pleckstrin homology-like domain, family B, member 1

chr8_+_13037308 0.075 ENSMUST00000063820.5
ENSMUST00000033821.4
F10

coagulation factor X

chr17_+_46650328 0.074 ENSMUST00000043464.7
Cul7
cullin 7
chr4_+_43493345 0.073 ENSMUST00000030181.5
ENSMUST00000107922.2
Ccdc107

coiled-coil domain containing 107

chr8_+_25808474 0.069 ENSMUST00000033979.4
Star
steroidogenic acute regulatory protein
chr8_+_105636509 0.068 ENSMUST00000005841.9
Ctcf
CCCTC-binding factor
chr17_-_85688252 0.065 ENSMUST00000024947.7
ENSMUST00000163568.2
Six2

sine oculis-related homeobox 2

chr7_-_100662414 0.062 ENSMUST00000079176.6
Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr19_-_42202150 0.058 ENSMUST00000018966.7
Sfrp5
secreted frizzled-related sequence protein 5
chr13_+_42709482 0.058 ENSMUST00000066928.5
ENSMUST00000148891.1
Phactr1

phosphatase and actin regulator 1

chr10_+_80019621 0.057 ENSMUST00000043311.6
Hmha1
histocompatibility (minor) HA-1
chr10_-_13388830 0.057 ENSMUST00000079698.5
Phactr2
phosphatase and actin regulator 2
chr12_-_69893162 0.054 ENSMUST00000049239.7
ENSMUST00000110570.1
Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr7_-_44892358 0.050 ENSMUST00000003049.6
Med25
mediator of RNA polymerase II transcription, subunit 25 homolog (yeast)
chr10_+_90576570 0.046 ENSMUST00000182786.1
ENSMUST00000182600.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr9_+_110052016 0.045 ENSMUST00000164930.1
ENSMUST00000163979.1
Map4

microtubule-associated protein 4

chr10_+_90576708 0.044 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
Anks1b



ankyrin repeat and sterile alpha motif domain containing 1B



chr6_-_136941694 0.044 ENSMUST00000032344.5
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr2_+_97467657 0.041 ENSMUST00000059049.7
Lrrc4c
leucine rich repeat containing 4C
chr15_-_50890396 0.038 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr4_+_124802543 0.038 ENSMUST00000138807.1
ENSMUST00000030723.2
ENSMUST00000175875.1
Mtf1


metal response element binding transcription factor 1


chr8_+_46490968 0.036 ENSMUST00000110372.1
ENSMUST00000130563.1
Acsl1

acyl-CoA synthetase long-chain family member 1

chr15_-_98607611 0.033 ENSMUST00000096224.4
Adcy6
adenylate cyclase 6
chr11_+_118428493 0.033 ENSMUST00000017590.2
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr11_+_118428203 0.033 ENSMUST00000124861.1
C1qtnf1
C1q and tumor necrosis factor related protein 1
chr9_-_77251871 0.032 ENSMUST00000183955.1
Mlip
muscular LMNA-interacting protein
chr10_+_90576252 0.026 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
Anks1b


ankyrin repeat and sterile alpha motif domain containing 1B


chr3_+_79885930 0.020 ENSMUST00000029567.8
Fam198b
family with sequence similarity 198, member B
chr3_-_84479418 0.016 ENSMUST00000091002.1
Fhdc1
FH2 domain containing 1
chr9_+_44069421 0.016 ENSMUST00000114830.2
Usp2
ubiquitin specific peptidase 2
chr10_+_90576777 0.015 ENSMUST00000183136.1
ENSMUST00000182595.1
Anks1b

ankyrin repeat and sterile alpha motif domain containing 1B

chr17_-_80480435 0.010 ENSMUST00000068714.5
Sos1
son of sevenless homolog 1 (Drosophila)
chr8_+_107436355 0.007 ENSMUST00000166615.1
Wwp2
WW domain containing E3 ubiquitin protein ligase 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0001955 blood vessel maturation(GO:0001955)
0.4 1.9 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.4 2.2 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.3 1.0 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.3 1.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.3 3.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.3 0.8 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.2 1.4 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.2 1.1 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.2 0.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.4 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 1.0 GO:0015862 uridine transport(GO:0015862)
0.1 0.7 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.1 1.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.3 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.8 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.3 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.1 0.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.6 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
0.1 0.2 GO:0048859 formation of anatomical boundary(GO:0048859)
0.1 0.6 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.6 GO:1901162 tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586) serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.5 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1 0.4 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:0071476 cellular hypotonic response(GO:0071476)
0.1 0.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.2 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.1 0.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1 0.8 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 1.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.3 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.6 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:0071455 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0 0.5 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 1.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.1 GO:0033762 response to glucagon(GO:0033762)
0.0 0.3 GO:0018065 protein-cofactor linkage(GO:0018065)
0.0 0.3 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 3.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 1.5 GO:0030168 platelet activation(GO:0030168)
0.0 0.6 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.8 GO:0021766 hippocampus development(GO:0021766)
0.0 0.0 GO:0035811 negative regulation of urine volume(GO:0035811)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0005861 troponin complex(GO:0005861)
0.2 1.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 3.1 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.6 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.2 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.8 GO:0097441 basilar dendrite(GO:0097441)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.3 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0071438 NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438)
0.0 1.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0099738 basal cortex(GO:0045180) cell cortex region(GO:0099738)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.0 0.1 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0030172 troponin C binding(GO:0030172)
0.3 0.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.3 1.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.2 0.6 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 0.7 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 0.5 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.2 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0004517 nitric-oxide synthase activity(GO:0004517) arginine binding(GO:0034618)
0.1 1.3 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 2.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 3.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.1 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.6 GO:0034711 inhibin binding(GO:0034711)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 0.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 1.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 1.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0030171 hydrogen ion channel activity(GO:0015252) voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.0 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.3 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.2 GO:0019531 bicarbonate transmembrane transporter activity(GO:0015106) oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 1.1 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0000987 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)