Motif ID: Gata2_Gata1

Z-value: 0.544

Transcription factors associated with Gata2_Gata1:

Gene SymbolEntrez IDGene Name
Gata1 ENSMUSG00000031162.8 Gata1
Gata2 ENSMUSG00000015053.8 Gata2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata2mm10_v2_chr6_+_88198656_881986750.692.6e-04Click!
Gata1mm10_v2_chrX_-_7967817_79679100.029.3e-01Click!


Activity profile for motif Gata2_Gata1.

activity profile for motif Gata2_Gata1


Sorted Z-values histogram for motif Gata2_Gata1

Sorted Z-values for motif Gata2_Gata1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gata2_Gata1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 153 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_84701430 3.038 ENSMUST00000037165.4
 Lyl1
lymphoblastomic leukemia 1
chr3_+_135825788 2.044 ENSMUST00000167390.1
 Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr16_-_95459245 1.888 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
 Erg



avian erythroblastosis virus E-26 (v-ets) oncogene related



chr16_+_45093611 1.651 ENSMUST00000099498.2
 Ccdc80
coiled-coil domain containing 80
chr16_+_45094036 1.580 ENSMUST00000061050.5
 Ccdc80
coiled-coil domain containing 80
chrX_-_107403295 1.433 ENSMUST00000033591.5
 Itm2a
integral membrane protein 2A
chr6_+_30541582 1.431 ENSMUST00000096066.4
 Cpa2
carboxypeptidase A2, pancreatic
chr7_-_4522427 1.372 ENSMUST00000098859.3
 Tnni3
troponin I, cardiac 3
chr1_-_162866502 1.297 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chrX_+_73757069 1.287 ENSMUST00000002079.6
 Plxnb3
plexin B3
chr6_+_125552948 1.226 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
 Vwf


Von Willebrand factor homolog


chr3_+_135826075 1.140 ENSMUST00000029810.5
 Slc39a8
solute carrier family 39 (metal ion transporter), member 8
chr2_+_70474923 1.108 ENSMUST00000100043.2
 Sp5
trans-acting transcription factor 5
chr13_+_38345716 1.050 ENSMUST00000171970.1
 Bmp6
bone morphogenetic protein 6
chr13_-_116309639 1.030 ENSMUST00000036060.6
 Isl1
ISL1 transcription factor, LIM/homeodomain
chr9_-_32541589 0.982 ENSMUST00000016231.7
 Fli1
Friend leukemia integration 1
chr17_-_45593626 0.958 ENSMUST00000163905.1
ENSMUST00000167692.1
 Slc29a1

solute carrier family 29 (nucleoside transporters), member 1

chr7_+_28833975 0.911 ENSMUST00000066723.8
 Lgals4
lectin, galactose binding, soluble 4
chr3_-_88000350 0.909 ENSMUST00000090971.5
 Bcan
brevican
chr7_-_4522794 0.846 ENSMUST00000140424.1
 Tnni3
troponin I, cardiac 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 3.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.4 3.0 GO:0001955 blood vessel maturation(GO:0001955)
0.4 2.2 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.4 1.9 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.0 1.5 GO:0030168 platelet activation(GO:0030168)
0.2 1.4 GO:0002317 plasma cell differentiation(GO:0002317) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.3 1.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 1.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 1.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.2 1.1 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 1.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.3 1.0 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) cardiac cell fate determination(GO:0060913)
0.1 1.0 GO:0015862 uridine transport(GO:0015862)
0.0 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.3 0.8 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 0.8 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.8 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.1 GO:0005614 interstitial matrix(GO:0005614)
0.4 2.2 GO:0005861 troponin complex(GO:0005861)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.3 GO:0097449 astrocyte projection(GO:0097449)
0.2 1.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.0 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 0.8 GO:0097441 basilar dendrite(GO:0097441)
0.2 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 0.6 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.0 0.2 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 3.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.7 2.2 GO:0030172 troponin C binding(GO:0030172)
0.1 2.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 1.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 1.3 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.1 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.0 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.0 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 1.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 0.8 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.8 GO:0016594 glycine binding(GO:0016594)
0.2 0.7 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.7 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)