Motif ID: Tfap2e
Z-value: 0.947
Transcription factors associated with Tfap2e:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Tfap2e | ENSMUSG00000042477.7 | Tfap2e |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Tfap2e | mm10_v2_chr4_-_126736236_126736245 | -0.56 | 5.2e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.4 | 14.1 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
0.9 | 2.6 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
0.8 | 2.5 | GO:0097212 | lysosomal membrane organization(GO:0097212) |
0.7 | 4.1 | GO:0042045 | epithelial fluid transport(GO:0042045) |
0.6 | 1.7 | GO:0072531 | pyrimidine-containing compound transmembrane transport(GO:0072531) |
0.5 | 5.0 | GO:0010459 | negative regulation of heart rate(GO:0010459) |
0.4 | 1.1 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
0.4 | 1.4 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
0.3 | 1.0 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.3 | 0.9 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
0.3 | 1.6 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.2 | 1.9 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
0.2 | 0.8 | GO:1904177 | regulation of adipose tissue development(GO:1904177) |
0.2 | 0.8 | GO:0097168 | condensed mesenchymal cell proliferation(GO:0072137) mesenchymal stem cell proliferation(GO:0097168) |
0.2 | 0.9 | GO:0089711 | L-glutamate transmembrane transport(GO:0089711) |
0.1 | 0.3 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
0.1 | 1.8 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.1 | 1.2 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.1 | 1.0 | GO:0033601 | positive regulation of mammary gland epithelial cell proliferation(GO:0033601) regulation of wound healing, spreading of epidermal cells(GO:1903689) |
0.1 | 0.7 | GO:0032811 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811) |
0.1 | 0.7 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
0.1 | 1.0 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
0.1 | 1.7 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
0.1 | 0.3 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
0.1 | 1.2 | GO:0006862 | nucleotide transport(GO:0006862) |
0.0 | 1.0 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.2 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
0.0 | 0.4 | GO:0042219 | cellular modified amino acid catabolic process(GO:0042219) |
0.0 | 1.4 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
0.0 | 0.1 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
0.0 | 0.1 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
0.0 | 0.2 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
0.0 | 0.2 | GO:1990403 | embryonic brain development(GO:1990403) |
0.0 | 0.3 | GO:0007271 | synaptic transmission, cholinergic(GO:0007271) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.5 | 14.1 | GO:0097450 | astrocyte end-foot(GO:0097450) |
1.4 | 4.1 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
0.3 | 0.9 | GO:0072534 | perineuronal net(GO:0072534) |
0.1 | 0.7 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
0.1 | 3.2 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
0.1 | 1.0 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
0.1 | 1.8 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
0.1 | 2.6 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
0.1 | 1.4 | GO:0000242 | pericentriolar material(GO:0000242) |
0.1 | 0.3 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
0.0 | 1.6 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
0.0 | 1.3 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
0.0 | 0.2 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.0 | 0.9 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.7 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 2.7 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 1.2 | GO:0005776 | autophagosome(GO:0005776) |
0.0 | 0.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
0.0 | 0.9 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 2.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
0.0 | 0.5 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.7 | GO:0005871 | kinesin complex(GO:0005871) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.4 | 4.1 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
0.5 | 2.1 | GO:0043125 | ErbB-3 class receptor binding(GO:0043125) |
0.5 | 2.6 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
0.4 | 1.2 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.2 | 0.9 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
0.2 | 14.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
0.2 | 2.9 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
0.1 | 0.3 | GO:0097016 | L27 domain binding(GO:0097016) |
0.1 | 2.8 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.1 | 0.7 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
0.1 | 0.7 | GO:0005042 | netrin receptor activity(GO:0005042) |
0.1 | 1.3 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
0.1 | 1.1 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
0.1 | 3.4 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
0.1 | 1.9 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.1 | 0.9 | GO:0046625 | sphingolipid binding(GO:0046625) |
0.1 | 0.3 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.0 | 0.3 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
0.0 | 0.4 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 1.1 | GO:0004697 | protein kinase C activity(GO:0004697) |
0.0 | 0.8 | GO:0005227 | calcium activated cation channel activity(GO:0005227) |
0.0 | 1.0 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
0.0 | 1.0 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |