Motif ID: Maff

Z-value: 0.482


Transcription factors associated with Maff:

Gene SymbolEntrez IDGene Name
Maff ENSMUSG00000042622.7 Maff

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Maffmm10_v2_chr15_+_79348061_793481540.155.0e-01Click!


Activity profile for motif Maff.

activity profile for motif Maff


Sorted Z-values histogram for motif Maff

Sorted Z-values for motif Maff



Network of associatons between targets according to the STRING database.



First level regulatory network of Maff

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_136886187 1.404 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chr15_+_3270767 1.252 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
Sepp1



selenoprotein P, plasma, 1



chr13_-_23710714 1.138 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr18_+_33464163 1.105 ENSMUST00000097634.3
Gm10549
predicted gene 10549
chr7_-_110862944 0.886 ENSMUST00000033050.3
Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr7_-_64925560 0.830 ENSMUST00000149851.1
Fam189a1
family with sequence similarity 189, member A1
chr13_+_48261427 0.753 ENSMUST00000021810.1
Id4
inhibitor of DNA binding 4
chr3_+_109573907 0.737 ENSMUST00000106576.2
Vav3
vav 3 oncogene
chr11_-_109473598 0.718 ENSMUST00000070152.5
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr17_-_25570678 0.614 ENSMUST00000025003.3
ENSMUST00000173447.1
Sox8

SRY-box containing gene 8

chr5_+_104435112 0.568 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
Spp1





secreted phosphoprotein 1





chr4_-_143299463 0.525 ENSMUST00000119654.1
Pdpn
podoplanin
chr19_-_8929323 0.512 ENSMUST00000096242.3
Rom1
rod outer segment membrane protein 1
chr18_+_60963517 0.474 ENSMUST00000115295.2
ENSMUST00000039904.6
Camk2a

calcium/calmodulin-dependent protein kinase II alpha

chr4_-_143299498 0.460 ENSMUST00000030317.7
Pdpn
podoplanin
chr6_+_120773633 0.392 ENSMUST00000112682.2
Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr18_+_4921662 0.371 ENSMUST00000143254.1
Svil
supervillin
chr1_-_120074023 0.370 ENSMUST00000056089.7
Tmem37
transmembrane protein 37
chr10_+_26078255 0.364 ENSMUST00000041011.3
Gm9767
predicted gene 9767
chr7_+_16944645 0.346 ENSMUST00000094807.5
Pnmal2
PNMA-like 2
chr16_+_72663143 0.343 ENSMUST00000023600.7
Robo1
roundabout homolog 1 (Drosophila)
chr1_+_136018062 0.304 ENSMUST00000117950.1
Tmem9
transmembrane protein 9
chr3_+_65109343 0.286 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1

potassium voltage-gated channel, shaker-related subfamily, beta member 1

chr1_+_136017967 0.283 ENSMUST00000063719.8
ENSMUST00000118832.1
Tmem9

transmembrane protein 9

chr19_+_8929628 0.260 ENSMUST00000096241.4
Eml3
echinoderm microtubule associated protein like 3
chr11_+_82101836 0.256 ENSMUST00000000194.3
Ccl12
chemokine (C-C motif) ligand 12
chr2_-_130397525 0.245 ENSMUST00000028897.7
Cpxm1
carboxypeptidase X 1 (M14 family)
chr13_-_54749849 0.219 ENSMUST00000135343.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr13_-_54749627 0.205 ENSMUST00000099506.1
Gprin1
G protein-regulated inducer of neurite outgrowth 1
chr9_-_122310921 0.185 ENSMUST00000180685.1
Gm26797
predicted gene, 26797
chr7_+_139214661 0.181 ENSMUST00000135509.1
Lrrc27
leucine rich repeat containing 27
chr4_-_25281752 0.147 ENSMUST00000038705.7
Ufl1
UFM1 specific ligase 1
chr5_+_106964319 0.145 ENSMUST00000031221.5
ENSMUST00000117196.2
ENSMUST00000076467.6
Cdc7


cell division cycle 7 (S. cerevisiae)


chr10_-_88605017 0.132 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr19_+_26753588 0.128 ENSMUST00000177116.1
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_+_84528964 0.125 ENSMUST00000180387.1
Gm2115
predicted gene 2115
chr5_+_7179299 0.124 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr4_-_25281801 0.122 ENSMUST00000102994.3
Ufl1
UFM1 specific ligase 1
chr2_-_127831817 0.121 ENSMUST00000028858.7
Bub1
budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
chr11_-_77078404 0.120 ENSMUST00000102494.1
Ccdc55
coiled-coil domain containing 55
chr7_-_44997535 0.117 ENSMUST00000124232.1
ENSMUST00000003290.4
Bcl2l12

BCL2-like 12 (proline rich)

chr2_+_121867083 0.117 ENSMUST00000089912.5
ENSMUST00000089915.3
Casc4

cancer susceptibility candidate 4

chr3_-_59262825 0.116 ENSMUST00000050360.7
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr14_+_118787894 0.110 ENSMUST00000047761.6
ENSMUST00000071546.7
Cldn10

claudin 10

chr9_-_111690313 0.109 ENSMUST00000035083.7
Stac
src homology three (SH3) and cysteine rich domain
chr16_-_16560201 0.095 ENSMUST00000162045.1
ENSMUST00000162124.1
ENSMUST00000161861.1
Fgd4


FYVE, RhoGEF and PH domain containing 4


chr3_-_116614587 0.092 ENSMUST00000041524.4
Trmt13
tRNA methyltransferase 13
chr8_+_46739745 0.082 ENSMUST00000034041.7
Irf2
interferon regulatory factor 2
chr2_-_69206133 0.079 ENSMUST00000112320.1
Spc25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr5_+_110839973 0.079 ENSMUST00000066160.1
Chek2
checkpoint kinase 2
chr7_-_4684963 0.078 ENSMUST00000079970.4
Hspbp1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr2_+_121866918 0.075 ENSMUST00000078752.3
ENSMUST00000110586.3
Casc4

cancer susceptibility candidate 4

chr17_-_67950908 0.070 ENSMUST00000164647.1
Arhgap28
Rho GTPase activating protein 28
chr11_-_106272927 0.068 ENSMUST00000021052.9
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr6_+_30401866 0.068 ENSMUST00000068240.6
ENSMUST00000068259.6
Klhdc10

kelch domain containing 10

chr12_-_80436571 0.066 ENSMUST00000054145.6
Dcaf5
DDB1 and CUL4 associated factor 5
chr11_-_116086929 0.066 ENSMUST00000074628.6
ENSMUST00000106444.3
Wbp2

WW domain binding protein 2

chr17_+_26138661 0.058 ENSMUST00000074370.3
ENSMUST00000118904.2
ENSMUST00000163421.1
Axin1


axin 1


chr19_+_56722372 0.057 ENSMUST00000038949.4
Adrb1
adrenergic receptor, beta 1
chr18_+_32377176 0.056 ENSMUST00000091967.5
ENSMUST00000025239.7
Bin1

bridging integrator 1

chr1_+_75382114 0.055 ENSMUST00000113590.1
ENSMUST00000148515.1
Speg

SPEG complex locus

chr11_+_76945719 0.054 ENSMUST00000125145.1
Blmh
bleomycin hydrolase
chr4_+_141239499 0.049 ENSMUST00000141834.2
Arhgef19
Rho guanine nucleotide exchange factor (GEF) 19
chr12_+_16894894 0.048 ENSMUST00000020904.6
Rock2
Rho-associated coiled-coil containing protein kinase 2
chr17_+_27839974 0.046 ENSMUST00000071006.7
Snrpc
U1 small nuclear ribonucleoprotein C
chr9_+_65214690 0.040 ENSMUST00000069000.7
Parp16
poly (ADP-ribose) polymerase family, member 16
chr5_-_35525691 0.036 ENSMUST00000038676.5
Cpz
carboxypeptidase Z
chr2_-_69206146 0.032 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
Spc25



SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)



chr13_-_85127514 0.027 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr6_+_83794974 0.023 ENSMUST00000037376.7
Nagk
N-acetylglucosamine kinase
chr4_+_94556546 0.021 ENSMUST00000094969.1
Gm10306
predicted gene 10306
chr6_+_83795022 0.018 ENSMUST00000113851.1
Nagk
N-acetylglucosamine kinase
chr19_-_4042165 0.017 ENSMUST00000042700.9
Gstp2
glutathione S-transferase, pi 2
chr15_-_78572754 0.017 ENSMUST00000043214.6
Rac2
RAS-related C3 botulinum substrate 2
chr5_-_121618865 0.012 ENSMUST00000041252.6
ENSMUST00000111776.1
Acad12

acyl-Coenzyme A dehydrogenase family, member 12

chr15_+_41789495 0.004 ENSMUST00000090095.5
ENSMUST00000022918.7
Oxr1

oxidation resistance 1

chr7_-_13037627 0.002 ENSMUST00000125964.1
Ube2m
ubiquitin-conjugating enzyme E2M

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.2 0.6 GO:0072034 renal vesicle induction(GO:0072034)
0.2 0.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 1.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.9 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 1.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.3 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 1.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.6 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.5 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:1900133 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) negative regulation of urine volume(GO:0035811) regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:1990357 terminal web(GO:1990357)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.3 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.3 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 1.0 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.1 1.3 GO:0008430 selenium binding(GO:0008430)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0051379 epinephrine binding(GO:0051379)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)