Motif ID: Sox8

Z-value: 0.417


Transcription factors associated with Sox8:

Gene SymbolEntrez IDGene Name
Sox8 ENSMUSG00000024176.4 Sox8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox8mm10_v2_chr17_-_25570678_25570694-0.771.7e-05Click!


Activity profile for motif Sox8.

activity profile for motif Sox8


Sorted Z-values histogram for motif Sox8

Sorted Z-values for motif Sox8



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox8

PNG image of the network

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Top targets:


Showing 1 to 20 of 49 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_8667033 1.777 ENSMUST00000042412.3
 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr18_-_62741387 1.034 ENSMUST00000097557.3
 Spink13
serine peptidase inhibitor, Kazal type 13
chr3_+_102010138 0.994 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr11_+_97415527 0.871 ENSMUST00000121799.1
 Arhgap23
Rho GTPase activating protein 23
chrX_+_134404780 0.830 ENSMUST00000113224.2
ENSMUST00000113226.1
 Drp2

dystrophin related protein 2

chr13_-_19395728 0.828 ENSMUST00000039694.7
 Stard3nl
STARD3 N-terminal like
chr19_+_24875679 0.732 ENSMUST00000073080.5
 Gm10053
predicted gene 10053
chr7_-_126800354 0.700 ENSMUST00000106348.1
 Aldoa
aldolase A, fructose-bisphosphate
chr13_-_66852017 0.688 ENSMUST00000059329.6
 Gm17449
predicted gene, 17449
chr1_+_109983737 0.681 ENSMUST00000172005.1
 Cdh7
cadherin 7, type 2
chr1_+_109993982 0.666 ENSMUST00000027542.6
 Cdh7
cadherin 7, type 2
chr7_-_126800036 0.610 ENSMUST00000133514.1
ENSMUST00000151137.1
 Aldoa

aldolase A, fructose-bisphosphate

chr10_-_128180265 0.575 ENSMUST00000099139.1
 Rbms2
RNA binding motif, single stranded interacting protein 2
chr11_+_69991633 0.571 ENSMUST00000108592.1
 Gabarap
gamma-aminobutyric acid receptor associated protein
chr8_+_34807287 0.518 ENSMUST00000033930.4
 Dusp4
dual specificity phosphatase 4
chr4_-_58553553 0.474 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
 Lpar1


lysophosphatidic acid receptor 1


chr13_-_66227573 0.415 ENSMUST00000167981.2
 Gm10772
predicted gene 10772
chr14_-_49783327 0.411 ENSMUST00000118129.1
ENSMUST00000036972.6
 3632451O06Rik

RIKEN cDNA 3632451O06 gene

chr15_-_103215285 0.382 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
 Cbx5


chromobox 5


chrX_-_23285532 0.352 ENSMUST00000115319.2
 Klhl13
kelch-like 13

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.8 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 1.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 1.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.0 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 1.0 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 0.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.2 GO:0001951 intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896)
0.0 0.2 GO:0072610 interleukin-12 secretion(GO:0072610) regulation of interleukin-12 secretion(GO:2001182) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0006553 lysine metabolic process(GO:0006553)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)

Gene overrepresentation in molecular_function category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 1.8 GO:0035939 microsatellite binding(GO:0035939)
0.2 1.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116)