Motif ID: Ddit3

Z-value: 0.495


Transcription factors associated with Ddit3:

Gene SymbolEntrez IDGene Name
Ddit3 ENSMUSG00000025408.9 Ddit3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ddit3mm10_v2_chr10_+_127290774_1272908030.048.6e-01Click!


Activity profile for motif Ddit3.

activity profile for motif Ddit3


Sorted Z-values histogram for motif Ddit3

Sorted Z-values for motif Ddit3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ddit3

PNG image of the network

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Top targets:


Showing 1 to 20 of 139 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 2.083 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr3_-_49757257 1.962 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr10_+_112271123 1.409 ENSMUST00000092175.2
 Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr5_+_3343893 1.382 ENSMUST00000165117.1
 Cdk6
cyclin-dependent kinase 6
chr5_-_114273702 1.093 ENSMUST00000144050.1
ENSMUST00000044790.5
 Foxn4

forkhead box N4

chr8_-_99416397 1.018 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
 Cdh8




cadherin 8




chr19_-_59076069 1.004 ENSMUST00000047511.7
ENSMUST00000163821.1
 4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr6_+_21215472 0.966 ENSMUST00000081542.5
 Kcnd2
potassium voltage-gated channel, Shal-related family, member 2
chr10_-_109823585 0.898 ENSMUST00000161582.1
 Nav3
neuron navigator 3
chr15_-_43869993 0.888 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr15_-_32244632 0.833 ENSMUST00000181536.1
 0610007N19Rik
RIKEN cDNA 0610007N19
chr3_-_53657339 0.758 ENSMUST00000091137.4
 Frem2
Fras1 related extracellular matrix protein 2
chr6_+_125494419 0.672 ENSMUST00000181266.1
 Gm26728
predicted gene, 26728
chr3_+_9403049 0.660 ENSMUST00000180874.1
ENSMUST00000181331.1
ENSMUST00000181930.1
 C030034L19Rik


RIKEN cDNA C030034L19 gene


chr15_+_32244801 0.629 ENSMUST00000067458.6
 Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr7_+_107370728 0.615 ENSMUST00000137663.1
ENSMUST00000073459.5
 Syt9

synaptotagmin IX

chr18_+_37421418 0.600 ENSMUST00000053073.4
 Pcdhb11
protocadherin beta 11
chr2_-_45117349 0.548 ENSMUST00000176438.2
 Zeb2
zinc finger E-box binding homeobox 2
chr9_-_44799179 0.532 ENSMUST00000114705.1
ENSMUST00000002100.7
 Tmem25

transmembrane protein 25

chr7_+_64287665 0.531 ENSMUST00000032736.4
 Mtmr10
myotubularin related protein 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 1.4 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2 1.4 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.1 1.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 1.0 GO:0045475 locomotor rhythm(GO:0045475)
0.0 1.0 GO:0009409 response to cold(GO:0009409)
0.1 0.9 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.1 0.5 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.5 GO:1902847 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of tau-protein kinase activity(GO:1902949)
0.1 0.5 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.5 GO:0051004 regulation of lipoprotein lipase activity(GO:0051004)
0.1 0.5 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 0.4 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961) calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.4 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.9 GO:0031430 M band(GO:0031430)
0.1 0.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0043219 catenin complex(GO:0016342) lateral loop(GO:0043219)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0005605 basal lamina(GO:0005605)
0.1 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.4 GO:0030332 cyclin binding(GO:0030332)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 1.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.9 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 0.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.5 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.3 GO:0004104 cholinesterase activity(GO:0004104) choline binding(GO:0033265)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.2 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)