Motif ID: Hoxb1

Z-value: 0.522


Transcription factors associated with Hoxb1:

Gene SymbolEntrez IDGene Name
Hoxb1 ENSMUSG00000018973.2 Hoxb1



Activity profile for motif Hoxb1.

activity profile for motif Hoxb1


Sorted Z-values histogram for motif Hoxb1

Sorted Z-values for motif Hoxb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 70 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_119053339 1.954 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
 Gli2


GLI-Kruppel family member GLI2


chr2_+_65845833 1.681 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chrX_+_143518671 1.407 ENSMUST00000134402.1
 Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr1_+_127306706 1.388 ENSMUST00000171405.1
 Mgat5
mannoside acetylglucosaminyltransferase 5
chr5_+_139543889 1.360 ENSMUST00000174792.1
ENSMUST00000031523.8
 Uncx

UNC homeobox

chr1_+_153665274 1.226 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr8_-_8639363 1.060 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr10_-_92162753 1.039 ENSMUST00000182197.1
 Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr7_+_73391160 1.032 ENSMUST00000128471.1
 Rgma
RGM domain family, member A
chr19_-_41743665 0.969 ENSMUST00000025993.3
 Slit1
slit homolog 1 (Drosophila)
chr2_+_65845767 0.820 ENSMUST00000122912.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr3_+_127633134 0.815 ENSMUST00000029587.7
 Neurog2
neurogenin 2
chr1_-_119053619 0.807 ENSMUST00000062483.8
 Gli2
GLI-Kruppel family member GLI2
chr12_+_38780284 0.649 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr4_+_103114712 0.644 ENSMUST00000143417.1
 Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr2_+_84840612 0.629 ENSMUST00000111625.1
 Slc43a1
solute carrier family 43, member 1
chr8_-_87959560 0.538 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr12_-_15816762 0.498 ENSMUST00000020922.7
 Trib2
tribbles homolog 2 (Drosophila)
chr10_+_4266323 0.471 ENSMUST00000045730.5
 Akap12
A kinase (PRKA) anchor protein (gravin) 12
chr10_-_63421739 0.462 ENSMUST00000054760.4
 Gm7075
predicted gene 7075

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.8 GO:0060032 notochord regression(GO:0060032)
0.0 2.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 1.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 1.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 1.4 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.1 1.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 1.1 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 1.0 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 1.0 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.7 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.5 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.4 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.3 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.3 GO:0031937 positive regulation of chromatin silencing(GO:0031937)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.8 GO:0097542 ciliary tip(GO:0097542)
0.0 1.2 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.3 1.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.0 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.0 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.8 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 0.6 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.1 GO:0035497 cAMP response element binding(GO:0035497)