Motif ID: Rara

Z-value: 0.729


Transcription factors associated with Rara:

Gene SymbolEntrez IDGene Name
Rara ENSMUSG00000037992.10 Rara

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Raramm10_v2_chr11_+_98960412_989604850.781.1e-05Click!


Activity profile for motif Rara.

activity profile for motif Rara


Sorted Z-values histogram for motif Rara

Sorted Z-values for motif Rara



Network of associatons between targets according to the STRING database.



First level regulatory network of Rara

PNG image of the network

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Top targets:


Showing 1 to 20 of 67 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_94875600 5.865 ENSMUST00000022195.10
 Otp
orthopedia homolog (Drosophila)
chr11_+_98960412 4.854 ENSMUST00000107473.2
 Rara
retinoic acid receptor, alpha
chr2_+_169633517 3.256 ENSMUST00000109157.1
 Tshz2
teashirt zinc finger family member 2
chr4_-_141599835 2.974 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
 Fblim1



filamin binding LIM protein 1



chr1_-_175692624 2.567 ENSMUST00000027809.7
 Opn3
opsin 3
chr17_+_34593388 2.236 ENSMUST00000174532.1
 Pbx2
pre B cell leukemia homeobox 2
chr3_-_54915867 2.074 ENSMUST00000070342.3
 Sertm1
serine rich and transmembrane domain containing 1
chr7_-_17056669 1.588 ENSMUST00000037762.4
 Hif3a
hypoxia inducible factor 3, alpha subunit
chr6_+_91157373 1.530 ENSMUST00000155007.1
 Hdac11
histone deacetylase 11
chr4_+_150853919 1.068 ENSMUST00000073600.2
 Errfi1
ERBB receptor feedback inhibitor 1
chr4_+_32238713 1.005 ENSMUST00000108180.2
 Bach2
BTB and CNC homology 2
chr2_-_5012716 1.003 ENSMUST00000027980.7
 Mcm10
minichromosome maintenance deficient 10 (S. cerevisiae)
chr2_+_5845243 0.964 ENSMUST00000127116.1
 Nudt5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr4_+_32238950 0.963 ENSMUST00000037416.6
 Bach2
BTB and CNC homology 2
chr14_+_58070547 0.959 ENSMUST00000165526.1
 Fgf9
fibroblast growth factor 9
chrX_+_106187100 0.898 ENSMUST00000081593.6
 Pgk1
phosphoglycerate kinase 1
chr10_+_4611971 0.819 ENSMUST00000105590.1
ENSMUST00000067086.7
 Esr1

estrogen receptor 1 (alpha)

chr12_-_108893197 0.811 ENSMUST00000161154.1
ENSMUST00000161410.1
 Wars

tryptophanyl-tRNA synthetase

chr11_+_94629741 0.801 ENSMUST00000021239.6
 Lrrc59
leucine rich repeat containing 59
chr10_-_89257790 0.653 ENSMUST00000045601.7
 Ano4
anoctamin 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
1.6 4.9 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 3.0 GO:0033623 regulation of integrin activation(GO:0033623)
0.9 2.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 1.5 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 1.5 GO:0014003 oligodendrocyte development(GO:0014003)
0.4 1.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 1.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 1.0 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.9 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.9 GO:0006094 gluconeogenesis(GO:0006094)
0.3 0.8 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.8 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.2 0.7 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 0.7 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.0 0.6 GO:0010883 regulation of lipid storage(GO:0010883)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.5 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.6 GO:0016607 nuclear speck(GO:0016607)
0.0 1.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 1.0 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.9 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.9 GO:0001972 retinoic acid binding(GO:0001972)
0.2 3.0 GO:0031005 filamin binding(GO:0031005)
0.9 2.6 GO:0009881 photoreceptor activity(GO:0009881)
0.2 2.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.2 1.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 0.9 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.3 0.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.3 0.8 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.6 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)