Motif ID: Sox17

Z-value: 0.507


Transcription factors associated with Sox17:

Gene SymbolEntrez IDGene Name
Sox17 ENSMUSG00000025902.7 Sox17

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox17mm10_v2_chr1_-_4496363_4496389-0.116.0e-01Click!


Activity profile for motif Sox17.

activity profile for motif Sox17


Sorted Z-values histogram for motif Sox17

Sorted Z-values for motif Sox17



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox17

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_23248264 2.543 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr8_-_105471481 2.308 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr6_+_121245903 1.372 ENSMUST00000032198.9
 Usp18
ubiquitin specific peptidase 18
chr2_-_180889660 1.028 ENSMUST00000137629.1
 Gm14342
predicted gene 14342
chr10_+_127725392 0.882 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr4_+_118961578 0.765 ENSMUST00000058651.4
 Lao1
L-amino acid oxidase 1
chr10_+_81821127 0.764 ENSMUST00000099439.3
 Gm4767
predicted gene 4767
chr10_+_81661998 0.762 ENSMUST00000105315.2
 Gm10778
predicted gene 10778
chr1_+_52008210 0.663 ENSMUST00000027277.5
 Stat4
signal transducer and activator of transcription 4
chr19_+_55741810 0.647 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr2_+_102659213 0.625 ENSMUST00000111213.1
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_-_107597577 0.607 ENSMUST00000100949.3
ENSMUST00000078021.6
 Glmn

glomulin, FKBP associated protein

chr1_+_135729147 0.550 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr10_+_59221945 0.527 ENSMUST00000182161.1
 Sowahc
sosondowah ankyrin repeat domain family member C
chrX_+_123103546 0.505 ENSMUST00000113348.1
 3110007F17Rik
RIKEN cDNA 3110007F17 gene
chr12_+_51348019 0.501 ENSMUST00000054308.6
 G2e3
G2/M-phase specific E3 ubiquitin ligase
chr5_-_107597533 0.499 ENSMUST00000124140.1
 Glmn
glomulin, FKBP associated protein
chr17_+_46428930 0.494 ENSMUST00000024764.5
ENSMUST00000165993.1
 Crip3

cysteine-rich protein 3

chrX_+_123103489 0.459 ENSMUST00000113343.1
 3110007F17Rik
RIKEN cDNA 3110007F17 gene
chr14_+_50944499 0.453 ENSMUST00000178092.1
 Pnp
purine-nucleoside phosphorylase
chr10_-_30655859 0.445 ENSMUST00000092610.4
 Ncoa7
nuclear receptor coactivator 7
chr11_-_86807624 0.437 ENSMUST00000018569.7
 Dhx40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr4_+_41903610 0.428 ENSMUST00000098128.3
 Gm21541
predicted gene, 21541
chr12_+_51348370 0.342 ENSMUST00000121521.1
 G2e3
G2/M-phase specific E3 ubiquitin ligase
chr11_-_77894096 0.336 ENSMUST00000017597.4
 Pipox
pipecolic acid oxidase
chr7_-_127890918 0.330 ENSMUST00000121394.1
 Prss53
protease, serine, 53
chr15_-_96460838 0.329 ENSMUST00000047835.6
 Scaf11
SR-related CTD-associated factor 11
chr6_-_148944750 0.327 ENSMUST00000111562.1
ENSMUST00000081956.5
 Fam60a

family with sequence similarity 60, member A

chrX_+_48695004 0.326 ENSMUST00000033433.2
 Rbmx2
RNA binding motif protein, X-linked 2
chr12_+_51348265 0.321 ENSMUST00000119211.1
 G2e3
G2/M-phase specific E3 ubiquitin ligase
chr4_-_42773993 0.305 ENSMUST00000095114.4
 Ccl21a
chemokine (C-C motif) ligand 21A (serine)
chr9_+_108392820 0.301 ENSMUST00000035234.4
 1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr18_-_36197343 0.300 ENSMUST00000115713.1
ENSMUST00000115712.1
 Nrg2

neuregulin 2

chr14_+_68083853 0.299 ENSMUST00000022639.7
 Nefl
neurofilament, light polypeptide
chr11_-_97775876 0.275 ENSMUST00000107576.1
 1700001P01Rik
RIKEN cDNA 1700001P01 gene
chr8_-_94098811 0.274 ENSMUST00000034206.4
 Bbs2
Bardet-Biedl syndrome 2 (human)
chr5_-_130002838 0.271 ENSMUST00000111308.1
ENSMUST00000111307.1
 Gusb

glucuronidase, beta

chr9_+_3335470 0.225 ENSMUST00000053407.5
 Alkbh8
alkB, alkylation repair homolog 8 (E. coli)
chr19_-_44107447 0.224 ENSMUST00000119591.1
ENSMUST00000026217.4
 Chuk

conserved helix-loop-helix ubiquitous kinase

chr7_-_100656953 0.218 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
 Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr2_+_18677002 0.208 ENSMUST00000028071.6
 Bmi1
Bmi1 polycomb ring finger oncogene
chr2_+_180598219 0.192 ENSMUST00000103059.1
 Col9a3
collagen, type IX, alpha 3
chr12_+_24708241 0.154 ENSMUST00000020980.5
 Rrm2
ribonucleotide reductase M2
chr6_+_125215551 0.152 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
 Vamp1


vesicle-associated membrane protein 1


chr5_-_123721007 0.144 ENSMUST00000031376.7
 Zcchc8
zinc finger, CCHC domain containing 8
chr18_+_35599219 0.139 ENSMUST00000115734.1
 Paip2
polyadenylate-binding protein-interacting protein 2
chr12_-_84400851 0.131 ENSMUST00000117286.1
 Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
chr2_+_55411790 0.130 ENSMUST00000155997.1
ENSMUST00000128307.1
 Gm14033

predicted gene 14033

chr5_+_26817357 0.127 ENSMUST00000071500.6
 Dpp6
dipeptidylpeptidase 6
chr5_-_38502107 0.113 ENSMUST00000005238.6
 Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr8_+_4248188 0.112 ENSMUST00000110993.1
 Gm14378
predicted gene 14378
chr2_-_4141128 0.111 ENSMUST00000154360.1
ENSMUST00000141488.1
ENSMUST00000155091.1
 1700080N15Rik


RIKEN cDNA 1700080N15 gene


chr8_-_41054771 0.109 ENSMUST00000093534.4
 Mtus1
mitochondrial tumor suppressor 1
chr9_+_82829806 0.108 ENSMUST00000113245.2
ENSMUST00000034783.4
 Irak1bp1

interleukin-1 receptor-associated kinase 1 binding protein 1

chr2_-_127133909 0.108 ENSMUST00000110387.3
 Ncaph
non-SMC condensin I complex, subunit H
chr4_-_119173849 0.103 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
 Zfp691


zinc finger protein 691


chr2_-_15049254 0.101 ENSMUST00000028034.8
ENSMUST00000114713.1
 Nsun6

NOL1/NOP2/Sun domain family member 6

chr2_-_142901506 0.097 ENSMUST00000043589.7
 Kif16b
kinesin family member 16B
chr10_-_59221757 0.090 ENSMUST00000165971.1
 Sept10
septin 10
chr7_+_16959714 0.087 ENSMUST00000038163.6
 Pnmal1
PNMA-like 1
chr9_+_66946057 0.079 ENSMUST00000040917.7
ENSMUST00000127896.1
 Rps27l

ribosomal protein S27-like

chr12_-_84400929 0.078 ENSMUST00000122194.1
 Entpd5
ectonucleoside triphosphate diphosphohydrolase 5
chr8_+_71887264 0.074 ENSMUST00000034259.7
 Zfp709
zinc finger protein 709
chr2_-_57113053 0.057 ENSMUST00000112627.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr3_-_158016419 0.052 ENSMUST00000127778.1
 Srsf11
serine/arginine-rich splicing factor 11
chr2_+_52857844 0.052 ENSMUST00000090952.4
ENSMUST00000049483.6
ENSMUST00000050719.6
 Fmnl2


formin-like 2


chr18_-_33213832 0.041 ENSMUST00000025236.2
 Stard4
StAR-related lipid transfer (START) domain containing 4
chr17_-_55712571 0.034 ENSMUST00000086876.5
 Pot1b
protection of telomeres 1B
chr11_+_78343475 0.031 ENSMUST00000002127.7
ENSMUST00000108295.1
 Unc119

unc-119 homolog (C. elegans)

chr19_+_6306456 0.027 ENSMUST00000025681.7
 Cdc42bpg
CDC42 binding protein kinase gamma (DMPK-like)
chr7_-_104353328 0.027 ENSMUST00000130139.1
ENSMUST00000059037.8
 Trim12c

tripartite motif-containing 12C

chr19_+_8920358 0.024 ENSMUST00000096243.5
 B3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr2_+_121456963 0.022 ENSMUST00000126764.1
 Hypk
huntingtin interacting protein K
chr11_+_78346666 0.018 ENSMUST00000100755.3
 Unc119
unc-119 homolog (C. elegans)
chr7_-_102210120 0.015 ENSMUST00000070165.5
 Nup98
nucleoporin 98
chr8_+_107150621 0.012 ENSMUST00000034400.3
 Cyb5b
cytochrome b5 type B
chr7_-_143549055 0.010 ENSMUST00000072727.5
 Nap1l4
nucleosome assembly protein 1-like 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 0.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:0006553 lysine metabolic process(GO:0006553)
0.1 1.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.2 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 2.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.8 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.0 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.2 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 1.2 GO:0001824 blastocyst development(GO:0001824)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.2 GO:0070820 tertiary granule(GO:0070820)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.3 0.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 1.4 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 2.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)