Motif ID: Sox17

Z-value: 0.507


Transcription factors associated with Sox17:

Gene SymbolEntrez IDGene Name
Sox17 ENSMUSG00000025902.7 Sox17

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Sox17mm10_v2_chr1_-_4496363_4496389-0.116.0e-01Click!


Activity profile for motif Sox17.

activity profile for motif Sox17


Sorted Z-values histogram for motif Sox17

Sorted Z-values for motif Sox17



Network of associatons between targets according to the STRING database.



First level regulatory network of Sox17

PNG image of the network

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Top targets:


Showing 1 to 20 of 77 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 2.543 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr8_-_105471481 2.308 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr6_+_121245903 1.372 ENSMUST00000032198.9
 Usp18
ubiquitin specific peptidase 18
chr2_-_180889660 1.028 ENSMUST00000137629.1
 Gm14342
predicted gene 14342
chr10_+_127725392 0.882 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr4_+_118961578 0.765 ENSMUST00000058651.4
 Lao1
L-amino acid oxidase 1
chr10_+_81821127 0.764 ENSMUST00000099439.3
 Gm4767
predicted gene 4767
chr10_+_81661998 0.762 ENSMUST00000105315.2
 Gm10778
predicted gene 10778
chr1_+_52008210 0.663 ENSMUST00000027277.5
 Stat4
signal transducer and activator of transcription 4
chr19_+_55741810 0.647 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
 Tcf7l2



transcription factor 7 like 2, T cell specific, HMG box



chr2_+_102659213 0.625 ENSMUST00000111213.1
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr5_-_107597577 0.607 ENSMUST00000100949.3
ENSMUST00000078021.6
 Glmn

glomulin, FKBP associated protein

chr1_+_135729147 0.550 ENSMUST00000027677.7
 Csrp1
cysteine and glycine-rich protein 1
chr10_+_59221945 0.527 ENSMUST00000182161.1
 Sowahc
sosondowah ankyrin repeat domain family member C
chrX_+_123103546 0.505 ENSMUST00000113348.1
 3110007F17Rik
RIKEN cDNA 3110007F17 gene
chr12_+_51348019 0.501 ENSMUST00000054308.6
 G2e3
G2/M-phase specific E3 ubiquitin ligase
chr5_-_107597533 0.499 ENSMUST00000124140.1
 Glmn
glomulin, FKBP associated protein
chr17_+_46428930 0.494 ENSMUST00000024764.5
ENSMUST00000165993.1
 Crip3

cysteine-rich protein 3

chrX_+_123103489 0.459 ENSMUST00000113343.1
 3110007F17Rik
RIKEN cDNA 3110007F17 gene
chr14_+_50944499 0.453 ENSMUST00000178092.1
 Pnp
purine-nucleoside phosphorylase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 2.5 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 2.3 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 1.2 GO:0001824 blastocyst development(GO:0001824)
0.1 1.1 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.1 0.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.8 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.1 0.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.2 0.5 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.3 GO:0006553 lysine metabolic process(GO:0006553)
0.1 0.3 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.3 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.2 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.2 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.6 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.6 GO:0030673 axolemma(GO:0030673)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.2 GO:0070820 tertiary granule(GO:0070820)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.4 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.4 1.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.3 0.8 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.2 0.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.3 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)