Motif ID: Rfx5

Z-value: 0.383


Transcription factors associated with Rfx5:

Gene SymbolEntrez IDGene Name
Rfx5 ENSMUSG00000005774.6 Rfx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx5mm10_v2_chr3_+_94954075_94954226-0.058.4e-01Click!


Activity profile for motif Rfx5.

activity profile for motif Rfx5


Sorted Z-values histogram for motif Rfx5

Sorted Z-values for motif Rfx5



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx5

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_34398802 0.526 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
 BC051142



cDNA sequence BC051142



chr11_+_117523526 0.521 ENSMUST00000132261.1
 Gm11734
predicted gene 11734
chr17_+_34135182 0.474 ENSMUST00000042121.9
 H2-DMa
histocompatibility 2, class II, locus DMa
chr17_+_34305883 0.418 ENSMUST00000074557.8
 H2-Eb1
histocompatibility 2, class II antigen E beta
chr7_-_45091713 0.348 ENSMUST00000141576.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr1_-_183147461 0.336 ENSMUST00000171366.1
 Disp1
dispatched homolog 1 (Drosophila)
chr9_+_21196705 0.329 ENSMUST00000003395.9
 Pde4a
phosphodiesterase 4A, cAMP specific
chr7_+_100537192 0.264 ENSMUST00000120454.1
 Coa4
cytochrome c oxidase assembly factor 4
chr17_+_35861343 0.264 ENSMUST00000172931.1
 Nrm
nurim (nuclear envelope membrane protein)
chr7_-_105752193 0.227 ENSMUST00000033184.4
 Tpp1
tripeptidyl peptidase I
chr2_-_92434027 0.203 ENSMUST00000111278.1
ENSMUST00000090559.5
 Cry2

cryptochrome 2 (photolyase-like)

chr1_+_134405984 0.200 ENSMUST00000173908.1
 Cyb5r1
cytochrome b5 reductase 1
chr4_-_35845204 0.186 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr17_+_37270214 0.185 ENSMUST00000038580.6
 H2-M3
histocompatibility 2, M region locus 3
chr2_-_152398046 0.165 ENSMUST00000063332.8
ENSMUST00000182625.1
 Sox12

SRY-box containing gene 12

chr7_+_44468020 0.165 ENSMUST00000117324.1
ENSMUST00000120852.1
ENSMUST00000118628.1
 Josd2


Josephin domain containing 2


chr7_+_44467980 0.157 ENSMUST00000035844.4
 Josd2
Josephin domain containing 2
chr18_+_60803838 0.155 ENSMUST00000050487.8
ENSMUST00000097563.2
ENSMUST00000167610.1
 Cd74


CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)


chr7_-_101921186 0.147 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
 Lrrc51


leucine rich repeat containing 51


chr7_+_44468051 0.146 ENSMUST00000118493.1
 Josd2
Josephin domain containing 2
chr17_+_35861318 0.140 ENSMUST00000074259.8
ENSMUST00000174873.1
 Nrm

nurim (nuclear envelope membrane protein)

chr7_+_100537052 0.132 ENSMUST00000054310.3
 Coa4
cytochrome c oxidase assembly factor 4
chr17_+_34187545 0.124 ENSMUST00000170086.1
 Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_24886304 0.121 ENSMUST00000044252.5
 Nubp2
nucleotide binding protein 2
chr14_+_55618023 0.120 ENSMUST00000002395.7
 Rec8
REC8 homolog (yeast)
chr8_-_85067982 0.114 ENSMUST00000177563.1
 Gm5741
predicted gene 5741
chr11_-_3539228 0.109 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
 Smtn



smoothelin



chr18_-_51865881 0.108 ENSMUST00000091905.2
 Gm4950
predicted pseudogene 4950
chr17_+_24886643 0.107 ENSMUST00000117890.1
ENSMUST00000168265.1
ENSMUST00000120943.1
ENSMUST00000068508.6
ENSMUST00000119829.1
 Spsb3




splA/ryanodine receptor domain and SOCS box containing 3




chr11_+_98682554 0.097 ENSMUST00000017365.8
 Psmd3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr9_+_44772951 0.091 ENSMUST00000128150.1
 Ift46
intraflagellar transport 46
chr5_-_125294107 0.090 ENSMUST00000127148.1
 Scarb1
scavenger receptor class B, member 1
chr9_+_44773191 0.082 ENSMUST00000147559.1
 Ift46
intraflagellar transport 46
chrX_+_42526585 0.082 ENSMUST00000101619.3
 Gm10483
predicted gene 10483
chr9_-_21291124 0.077 ENSMUST00000086374.6
 Cdkn2d
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr7_-_19692596 0.077 ENSMUST00000108451.2
ENSMUST00000045035.4
 Apoc1

apolipoprotein C-I

chr17_+_34187789 0.075 ENSMUST00000041633.8
 Tap1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr19_+_34217588 0.073 ENSMUST00000119603.1
 Stambpl1
STAM binding protein like 1
chr3_-_95882031 0.072 ENSMUST00000161994.1
 Gm129
predicted gene 129
chr9_+_44773027 0.071 ENSMUST00000125877.1
 Ift46
intraflagellar transport 46
chr8_+_84969587 0.068 ENSMUST00000109734.1
ENSMUST00000005292.8
 Prdx2

peroxiredoxin 2

chr7_-_101921175 0.061 ENSMUST00000098236.2
 Lrrc51
leucine rich repeat containing 51
chr6_+_94500313 0.057 ENSMUST00000061118.8
 Slc25a26
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26
chr19_-_10482874 0.055 ENSMUST00000038842.3
 Ppp1r32
protein phosphatase 1, regulatory subunit 32
chr17_+_34263209 0.054 ENSMUST00000040828.5
 H2-Ab1
histocompatibility 2, class II antigen A, beta 1
chr7_-_30664986 0.049 ENSMUST00000019697.8
 Haus5
HAUS augmin-like complex, subunit 5
chr10_-_7663245 0.048 ENSMUST00000163085.1
ENSMUST00000159917.1
 Pcmt1

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

chr8_-_89187560 0.047 ENSMUST00000093326.2
 Gm5356
predicted pseudogene 5356
chr2_-_128687354 0.043 ENSMUST00000110332.1
ENSMUST00000110333.1
ENSMUST00000014499.3
 Anapc1


anaphase promoting complex subunit 1


chr9_+_44772909 0.041 ENSMUST00000002099.3
 Ift46
intraflagellar transport 46
chr5_+_139150211 0.039 ENSMUST00000026975.6
 Heatr2
HEAT repeat containing 2
chr7_+_46841475 0.037 ENSMUST00000147535.1
 Ldha
lactate dehydrogenase A
chr10_-_78307550 0.035 ENSMUST00000150828.1
 Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr4_+_107968332 0.035 ENSMUST00000106713.3
 Slc1a7
solute carrier family 1 (glutamate transporter), member 7
chr2_+_163438455 0.032 ENSMUST00000109420.3
ENSMUST00000109421.3
ENSMUST00000018087.6
ENSMUST00000137070.1
 Gdap1l1



ganglioside-induced differentiation-associated protein 1-like 1



chr19_-_4615647 0.032 ENSMUST00000113822.2
 Lrfn4
leucine rich repeat and fibronectin type III domain containing 4
chr8_+_94214567 0.031 ENSMUST00000079961.6
 Nup93
nucleoporin 93
chr11_+_61505138 0.029 ENSMUST00000102657.3
 B9d1
B9 protein domain 1
chr10_-_7663569 0.027 ENSMUST00000162606.1
 Pcmt1
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
chr7_-_45092130 0.026 ENSMUST00000148175.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr17_-_34187219 0.025 ENSMUST00000173831.1
 Psmb9
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr10_-_19011948 0.021 ENSMUST00000105527.1
 Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr12_+_108334341 0.018 ENSMUST00000021684.4
 Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr5_-_36830647 0.014 ENSMUST00000031002.3
 Man2b2
mannosidase 2, alpha B2
chr10_-_127263346 0.012 ENSMUST00000099172.3
 Kif5a
kinesin family member 5A
chr6_-_83831736 0.005 ENSMUST00000058383.8
 Paip2b
poly(A) binding protein interacting protein 2B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 0.2 GO:2000832 protein-chromophore linkage(GO:0018298) negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.2 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0002901 positive regulation of dendritic cell antigen processing and presentation(GO:0002606) mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.0 0.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.3 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.3 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.5 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0023026 MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)