Motif ID: Rfx5

Z-value: 0.383


Transcription factors associated with Rfx5:

Gene SymbolEntrez IDGene Name
Rfx5 ENSMUSG00000005774.6 Rfx5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Rfx5mm10_v2_chr3_+_94954075_94954226-0.058.4e-01Click!


Activity profile for motif Rfx5.

activity profile for motif Rfx5


Sorted Z-values histogram for motif Rfx5

Sorted Z-values for motif Rfx5



Network of associatons between targets according to the STRING database.



First level regulatory network of Rfx5

PNG image of the network

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Top targets:


Showing 1 to 20 of 66 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_34398802 0.526 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
 BC051142



cDNA sequence BC051142



chr11_+_117523526 0.521 ENSMUST00000132261.1
 Gm11734
predicted gene 11734
chr17_+_34135182 0.474 ENSMUST00000042121.9
 H2-DMa
histocompatibility 2, class II, locus DMa
chr17_+_34305883 0.418 ENSMUST00000074557.8
 H2-Eb1
histocompatibility 2, class II antigen E beta
chr7_-_45091713 0.348 ENSMUST00000141576.1
 Rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr1_-_183147461 0.336 ENSMUST00000171366.1
 Disp1
dispatched homolog 1 (Drosophila)
chr9_+_21196705 0.329 ENSMUST00000003395.9
 Pde4a
phosphodiesterase 4A, cAMP specific
chr7_+_100537192 0.264 ENSMUST00000120454.1
 Coa4
cytochrome c oxidase assembly factor 4
chr17_+_35861343 0.264 ENSMUST00000172931.1
 Nrm
nurim (nuclear envelope membrane protein)
chr7_-_105752193 0.227 ENSMUST00000033184.4
 Tpp1
tripeptidyl peptidase I
chr2_-_92434027 0.203 ENSMUST00000111278.1
ENSMUST00000090559.5
 Cry2

cryptochrome 2 (photolyase-like)

chr1_+_134405984 0.200 ENSMUST00000173908.1
 Cyb5r1
cytochrome b5 reductase 1
chr4_-_35845204 0.186 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr17_+_37270214 0.185 ENSMUST00000038580.6
 H2-M3
histocompatibility 2, M region locus 3
chr2_-_152398046 0.165 ENSMUST00000063332.8
ENSMUST00000182625.1
 Sox12

SRY-box containing gene 12

chr7_+_44468020 0.165 ENSMUST00000117324.1
ENSMUST00000120852.1
ENSMUST00000118628.1
 Josd2


Josephin domain containing 2


chr7_+_44467980 0.157 ENSMUST00000035844.4
 Josd2
Josephin domain containing 2
chr18_+_60803838 0.155 ENSMUST00000050487.8
ENSMUST00000097563.2
ENSMUST00000167610.1
 Cd74


CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)


chr7_-_101921186 0.147 ENSMUST00000106965.1
ENSMUST00000106968.1
ENSMUST00000106967.1
 Lrrc51


leucine rich repeat containing 51


chr7_+_44468051 0.146 ENSMUST00000118493.1
 Josd2
Josephin domain containing 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 0.5 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.4 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.2 GO:2000832 protein-chromophore linkage(GO:0018298) negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.2 GO:0002765 immune response-inhibiting signal transduction(GO:0002765)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0002901 positive regulation of dendritic cell antigen processing and presentation(GO:0002606) mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0048102 autophagic cell death(GO:0048102)

Gene overrepresentation in cellular_component category:

Showing 1 to 6 of 6 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.8 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.3 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.2 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0000798 nuclear cohesin complex(GO:0000798) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.3 GO:0015197 peptide transporter activity(GO:0015197)
0.1 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.1 0.2 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0023026 MHC protein complex binding(GO:0023023) MHC class II protein complex binding(GO:0023026)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)