Motif ID: Etv6

Z-value: 0.585


Transcription factors associated with Etv6:

Gene SymbolEntrez IDGene Name
Etv6 ENSMUSG00000030199.10 Etv6

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Etv6mm10_v2_chr6_+_134035691_134035717-0.174.3e-01Click!


Activity profile for motif Etv6.

activity profile for motif Etv6


Sorted Z-values histogram for motif Etv6

Sorted Z-values for motif Etv6



Network of associatons between targets according to the STRING database.



First level regulatory network of Etv6

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_183221529 0.486 ENSMUST00000003035.5
 Disp1
dispatched homolog 1 (Drosophila)
chr2_+_168230597 0.425 ENSMUST00000099071.3
 Mocs3
molybdenum cofactor synthesis 3
chr2_+_180257373 0.397 ENSMUST00000059080.6
 Rps21
ribosomal protein S21
chr3_-_95871367 0.395 ENSMUST00000142437.1
ENSMUST00000067298.4
 Mrps21

mitochondrial ribosomal protein S21

chr3_-_94886945 0.390 ENSMUST00000005923.6
 Psmb4
proteasome (prosome, macropain) subunit, beta type 4
chr17_+_35135463 0.389 ENSMUST00000173535.1
ENSMUST00000173952.1
 Bag6

BCL2-associated athanogene 6

chr9_-_78489141 0.389 ENSMUST00000154207.1
 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr1_+_58586381 0.379 ENSMUST00000027193.8
 Ndufb3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3
chr4_+_118409331 0.378 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
 Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr13_+_4191163 0.368 ENSMUST00000021634.2
 Akr1c13
aldo-keto reductase family 1, member C13
chr11_-_120457936 0.359 ENSMUST00000137632.1
ENSMUST00000044007.2
 Oxld1

oxidoreductase like domain containing 1

chr7_-_105744312 0.346 ENSMUST00000141116.1
 Taf10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_-_4546567 0.346 ENSMUST00000065957.5
 Syt5
synaptotagmin V
chr7_+_44850393 0.343 ENSMUST00000136232.1
 Akt1s1
AKT1 substrate 1 (proline-rich)
chr15_-_34443508 0.342 ENSMUST00000079735.5
 Rpl30
ribosomal protein L30
chr9_+_48450327 0.340 ENSMUST00000165252.1
 Gm5616
predicted gene 5616
chr1_+_33669816 0.333 ENSMUST00000051203.5
 1700001G17Rik
RIKEN cDNA 1700001G17 gene
chr9_-_21149894 0.331 ENSMUST00000019615.9
 Cdc37
cell division cycle 37
chr17_+_35135695 0.330 ENSMUST00000174478.1
ENSMUST00000174281.2
ENSMUST00000173550.1
 Bag6


BCL2-associated athanogene 6


chr3_+_89430261 0.329 ENSMUST00000060061.4
 Pygo2
pygopus 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 1.2 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 0.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.8 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 0.6 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.5 GO:0060539 diaphragm development(GO:0060539)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.5 GO:0045116 protein neddylation(GO:0045116)
0.1 0.4 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 0.4 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 0.4 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.4 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.4 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.4 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.2 0.3 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 1.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 0.8 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.2 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.5 GO:0000243 commitment complex(GO:0000243)
0.0 0.5 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.4 GO:0030894 replisome(GO:0030894)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.1 0.3 GO:0000125 PCAF complex(GO:0000125)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 52 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.2 GO:0070628 proteasome binding(GO:0070628)
0.1 1.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.9 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.8 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 0.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.6 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.5 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.5 GO:0043022 ribosome binding(GO:0043022)
0.1 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)