Motif ID: Spib

Z-value: 0.742


Transcription factors associated with Spib:

Gene SymbolEntrez IDGene Name
Spib ENSMUSG00000008193.7 Spib



Activity profile for motif Spib.

activity profile for motif Spib


Sorted Z-values histogram for motif Spib

Sorted Z-values for motif Spib



Network of associatons between targets according to the STRING database.



First level regulatory network of Spib

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 5.096 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr6_+_137410721 2.400 ENSMUST00000167002.1
 Ptpro
protein tyrosine phosphatase, receptor type, O
chr17_+_93199348 2.331 ENSMUST00000064775.6
 Adcyap1
adenylate cyclase activating polypeptide 1
chr10_-_6980376 2.197 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr2_-_166155624 1.937 ENSMUST00000109249.2
 Sulf2
sulfatase 2
chr2_-_166155272 1.936 ENSMUST00000088086.3
 Sulf2
sulfatase 2
chr5_+_81021202 1.817 ENSMUST00000117253.1
ENSMUST00000120128.1
 Lphn3

latrophilin 3

chr6_-_72235559 1.781 ENSMUST00000042646.7
 Atoh8
atonal homolog 8 (Drosophila)
chr5_+_149265035 1.619 ENSMUST00000130144.1
ENSMUST00000071130.3
 Alox5ap

arachidonate 5-lipoxygenase activating protein

chr6_-_136941694 1.431 ENSMUST00000032344.5
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr4_+_118409331 1.424 ENSMUST00000084319.4
ENSMUST00000106384.3
ENSMUST00000126089.1
ENSMUST00000073881.1
ENSMUST00000019229.8
ENSMUST00000144577.1
 Med8





mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)





chr2_+_169633517 1.412 ENSMUST00000109157.1
 Tshz2
teashirt zinc finger family member 2
chr10_+_86302854 1.356 ENSMUST00000132307.1
 Timp3
tissue inhibitor of metalloproteinase 3
chr2_+_169632996 1.348 ENSMUST00000109159.2
 Tshz2
teashirt zinc finger family member 2
chr4_+_36952930 1.223 ENSMUST00000144029.1
 Gm12371
predicted gene 12371
chr13_+_5861489 1.065 ENSMUST00000000080.6
 Klf6
Kruppel-like factor 6
chr6_-_136941494 1.063 ENSMUST00000111892.1
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr8_+_108714644 1.015 ENSMUST00000043896.8
 Zfhx3
zinc finger homeobox 3
chr7_-_126704736 0.963 ENSMUST00000131415.1
 Coro1a
coronin, actin binding protein 1A
chrX_-_43167817 0.914 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 92 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 5.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.0 3.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.5 2.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.5 2.4 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.8 2.3 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of somatostatin secretion(GO:0090274)
0.4 2.3 GO:0032796 uropod organization(GO:0032796)
0.0 2.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.1 1.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.5 1.6 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538)
0.3 1.4 GO:1903984 negative regulation of membrane protein ectodomain proteolysis(GO:0051045) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 1.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.1 1.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 1.1 GO:0032091 negative regulation of protein binding(GO:0032091)
0.3 1.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 0.9 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.9 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.8 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.8 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.8 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.2 0.7 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.3 GO:0043195 terminal bouton(GO:0043195)
0.2 2.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0030315 T-tubule(GO:0030315)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.2 0.8 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.7 GO:0008278 cohesin complex(GO:0008278)
0.0 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.6 GO:0071439 clathrin complex(GO:0071439)
0.0 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.8 3.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 3.3 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 2.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 2.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 2.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.1 GO:0070888 E-box binding(GO:0070888)
0.1 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 1.6 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 1.1 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 0.6 GO:0019770 IgG receptor activity(GO:0019770)