Motif ID: Ebf3

Z-value: 1.314


Transcription factors associated with Ebf3:

Gene SymbolEntrez IDGene Name
Ebf3 ENSMUSG00000010476.7 Ebf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ebf3mm10_v2_chr7_-_137314394_137314445-0.462.9e-02Click!


Activity profile for motif Ebf3.

activity profile for motif Ebf3


Sorted Z-values histogram for motif Ebf3

Sorted Z-values for motif Ebf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Ebf3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_66812593 8.099 ENSMUST00000100572.3
 Sla
src-like adaptor
chr5_+_117781017 4.943 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr2_-_118703963 3.637 ENSMUST00000104937.1
 Ankrd63
ankyrin repeat domain 63
chr1_-_56969827 3.613 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr1_-_56969864 3.407 ENSMUST00000177424.1
 Satb2
special AT-rich sequence binding protein 2
chr7_+_123982799 3.045 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr4_-_129121234 2.702 ENSMUST00000030572.3
 Hpca
hippocalcin
chr15_+_99224976 2.431 ENSMUST00000041415.3
 Kcnh3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr15_-_45114926 2.399 ENSMUST00000022967.5
 Kcnv1
potassium channel, subfamily V, member 1
chr9_+_89909775 2.365 ENSMUST00000034912.4
ENSMUST00000034909.4
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr4_-_129121699 2.190 ENSMUST00000135763.1
ENSMUST00000149763.1
ENSMUST00000164649.1
 Hpca


hippocalcin


chr15_-_98677451 2.159 ENSMUST00000120997.1
ENSMUST00000109149.2
ENSMUST00000003451.4
 Rnd1


Rho family GTPase 1


chr19_+_43440404 2.138 ENSMUST00000165311.1
 Cnnm1
cyclin M1
chr3_+_26331150 2.050 ENSMUST00000099182.2
 A830092H15Rik
RIKEN cDNA A830092H15 gene
chr7_+_27607748 1.871 ENSMUST00000136962.1
 Akt2
thymoma viral proto-oncogene 2
chr1_-_154725920 1.867 ENSMUST00000004214.8
 Cacna1e
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr7_+_27607997 1.855 ENSMUST00000142365.1
 Akt2
thymoma viral proto-oncogene 2
chr9_-_64022043 1.851 ENSMUST00000041029.5
 Smad6
SMAD family member 6
chr1_+_75400070 1.779 ENSMUST00000113589.1
 Speg
SPEG complex locus
chr6_-_32588192 1.672 ENSMUST00000115096.2
 Plxna4
plexin A4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 142 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.0 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.6 4.9 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
1.2 4.9 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
0.3 4.6 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.3 3.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4 2.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 2.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 2.3 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 2.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.5 1.9 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.4 1.9 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.2 1.9 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.4 1.7 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.1 1.7 GO:0001990 regulation of systemic arterial blood pressure by hormone(GO:0001990)
0.5 1.6 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.5 1.6 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 1.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.3 1.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 1.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 1.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 72 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.5 GO:0005768 endosome(GO:0005768)
0.1 7.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.5 4.9 GO:0044327 dendritic spine head(GO:0044327)
0.4 4.9 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.5 4.6 GO:0045298 tubulin complex(GO:0045298)
0.2 3.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 2.1 GO:0043235 receptor complex(GO:0043235)
0.0 2.0 GO:0031941 filamentous actin(GO:0031941)
0.2 1.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.2 1.6 GO:0008278 cohesin complex(GO:0008278)
0.1 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.5 1.5 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.5 1.5 GO:0045160 myosin I complex(GO:0045160)
0.1 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.5 GO:0071564 npBAF complex(GO:0071564)
0.3 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.4 GO:0031045 dense core granule(GO:0031045)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 97 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.7 GO:0003682 chromatin binding(GO:0003682)
0.2 5.2 GO:0034185 apolipoprotein binding(GO:0034185)
1.6 4.9 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 3.9 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 3.7 GO:0005080 protein kinase C binding(GO:0005080)
0.1 3.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.2 2.8 GO:0015026 coreceptor activity(GO:0015026)
0.4 2.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 2.4 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.6 2.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 2.2 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.2 2.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.3 1.9 GO:0070697 activin receptor binding(GO:0070697)
0.1 1.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 1.7 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 1.7 GO:0015485 cholesterol binding(GO:0015485)
0.2 1.5 GO:0005042 netrin receptor activity(GO:0005042)
0.0 1.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 1.4 GO:0061133 endopeptidase activator activity(GO:0061133)