Motif ID: Ebf3
Z-value: 1.314
Transcription factors associated with Ebf3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Ebf3 | ENSMUSG00000010476.7 | Ebf3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ebf3 | mm10_v2_chr7_-_137314394_137314445 | -0.46 | 2.9e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.9 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 1.2 | 4.9 | GO:1901204 | positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) |
| 0.5 | 1.6 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
| 0.5 | 1.6 | GO:1902460 | regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462) |
| 0.5 | 1.4 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.5 | 1.4 | GO:1904395 | regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 0.5 | 1.9 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.4 | 7.0 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.4 | 1.7 | GO:0021564 | glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564) |
| 0.4 | 2.4 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.4 | 1.2 | GO:0003219 | cardiac right ventricle formation(GO:0003219) |
| 0.4 | 1.9 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) |
| 0.3 | 3.7 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.3 | 0.9 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 0.3 | 1.5 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.3 | 4.6 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
| 0.2 | 0.5 | GO:2000974 | negative regulation of pro-B cell differentiation(GO:2000974) |
| 0.2 | 0.7 | GO:1900041 | intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896) |
| 0.2 | 0.9 | GO:0035878 | nail development(GO:0035878) |
| 0.2 | 0.7 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474) |
| 0.2 | 0.9 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
| 0.2 | 0.8 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
| 0.2 | 1.9 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.2 | 1.0 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.2 | 1.0 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
| 0.2 | 0.8 | GO:1904425 | negative regulation of GTP binding(GO:1904425) |
| 0.2 | 1.5 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.2 | 2.1 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.2 | 0.9 | GO:0030091 | protein repair(GO:0030091) |
| 0.2 | 0.5 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.2 | 0.8 | GO:2000157 | regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157) |
| 0.2 | 0.5 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.2 | 0.3 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.1 | 1.0 | GO:1903300 | negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300) |
| 0.1 | 2.3 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.1 | 0.4 | GO:2001187 | positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187) |
| 0.1 | 0.6 | GO:0072675 | osteoclast fusion(GO:0072675) |
| 0.1 | 0.7 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.1 | 2.4 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.1 | 0.8 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
| 0.1 | 0.9 | GO:0061092 | involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.1 | 0.7 | GO:0070278 | extracellular matrix constituent secretion(GO:0070278) |
| 0.1 | 0.5 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.1 | 0.7 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375) |
| 0.1 | 0.7 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.1 | 0.3 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 0.1 | 0.7 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.1 | 0.7 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.1 | 0.5 | GO:0046929 | negative regulation of neurotransmitter secretion(GO:0046929) |
| 0.1 | 1.5 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.1 | 0.5 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.1 | 0.9 | GO:0031642 | negative regulation of myelination(GO:0031642) |
| 0.1 | 1.3 | GO:0001553 | luteinization(GO:0001553) |
| 0.1 | 0.3 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
| 0.1 | 0.8 | GO:0070447 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) |
| 0.1 | 0.5 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.1 | 0.3 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.1 | 0.4 | GO:2000551 | positive regulation of T-helper 2 cell differentiation(GO:0045630) regulation of T-helper 2 cell cytokine production(GO:2000551) positive regulation of T-helper 2 cell cytokine production(GO:2000553) |
| 0.1 | 1.2 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 0.5 | GO:0072318 | clathrin coat disassembly(GO:0072318) |
| 0.1 | 0.4 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.1 | 1.0 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 0.1 | 0.7 | GO:0006105 | succinyl-CoA metabolic process(GO:0006104) succinate metabolic process(GO:0006105) |
| 0.1 | 1.7 | GO:0001990 | regulation of systemic arterial blood pressure by hormone(GO:0001990) |
| 0.1 | 0.4 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.1 | 1.2 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.1 | 0.4 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.1 | 0.6 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.1 | 1.6 | GO:0010971 | positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) |
| 0.1 | 0.6 | GO:0006362 | transcription elongation from RNA polymerase I promoter(GO:0006362) |
| 0.1 | 1.0 | GO:0097062 | dendritic spine maintenance(GO:0097062) |
| 0.1 | 0.6 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.1 | 0.6 | GO:0051386 | regulation of neurotrophin TRK receptor signaling pathway(GO:0051386) |
| 0.1 | 0.3 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.1 | 1.0 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
| 0.1 | 1.0 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 0.4 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.1 | 0.6 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 0.1 | 0.3 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 0.1 | 0.2 | GO:2001045 | closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.1 | 0.9 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 0.1 | 0.6 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.0 | 0.6 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.0 | 0.6 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.0 | 0.9 | GO:0021516 | dorsal spinal cord development(GO:0021516) |
| 0.0 | 0.8 | GO:0052646 | alditol phosphate metabolic process(GO:0052646) |
| 0.0 | 1.0 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
| 0.0 | 0.2 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.0 | 0.2 | GO:0032298 | positive regulation of DNA-dependent DNA replication initiation(GO:0032298) |
| 0.0 | 0.3 | GO:0070813 | hydrogen sulfide metabolic process(GO:0070813) |
| 0.0 | 0.5 | GO:0035767 | endothelial cell chemotaxis(GO:0035767) |
| 0.0 | 0.3 | GO:0071243 | cellular response to arsenic-containing substance(GO:0071243) |
| 0.0 | 0.7 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.0 | 0.1 | GO:0002865 | negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) |
| 0.0 | 0.5 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.0 | 0.4 | GO:0032703 | negative regulation of interleukin-2 production(GO:0032703) |
| 0.0 | 0.1 | GO:0033326 | cerebrospinal fluid secretion(GO:0033326) |
| 0.0 | 1.5 | GO:1901016 | regulation of potassium ion transmembrane transporter activity(GO:1901016) |
| 0.0 | 0.1 | GO:2000983 | regulation of ATP citrate synthase activity(GO:2000983) negative regulation of ATP citrate synthase activity(GO:2000984) |
| 0.0 | 0.8 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.0 | 0.8 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.1 | GO:2000334 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.0 | 0.7 | GO:0001921 | positive regulation of receptor recycling(GO:0001921) |
| 0.0 | 0.2 | GO:0051503 | adenine nucleotide transport(GO:0051503) |
| 0.0 | 0.5 | GO:0070207 | protein homotrimerization(GO:0070207) |
| 0.0 | 0.4 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.0 | 0.9 | GO:0042246 | tissue regeneration(GO:0042246) |
| 0.0 | 0.2 | GO:0010759 | positive regulation of macrophage chemotaxis(GO:0010759) |
| 0.0 | 0.2 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.0 | 0.1 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.0 | 0.3 | GO:0045792 | negative regulation of cell size(GO:0045792) |
| 0.0 | 0.8 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.0 | 0.8 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.0 | 0.1 | GO:0048682 | axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682) |
| 0.0 | 0.2 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.0 | 0.3 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.0 | 0.2 | GO:0043206 | extracellular fibril organization(GO:0043206) |
| 0.0 | 0.5 | GO:0051443 | positive regulation of ubiquitin-protein transferase activity(GO:0051443) |
| 0.0 | 0.2 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.0 | 0.6 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 0.8 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.0 | 0.2 | GO:0060836 | lymphatic endothelial cell differentiation(GO:0060836) |
| 0.0 | 0.3 | GO:0045907 | positive regulation of vasoconstriction(GO:0045907) |
| 0.0 | 0.1 | GO:0016322 | neuron remodeling(GO:0016322) |
| 0.0 | 0.1 | GO:0006824 | cobalt ion transport(GO:0006824) |
| 0.0 | 1.3 | GO:0043966 | histone H3 acetylation(GO:0043966) |
| 0.0 | 0.6 | GO:0008333 | endosome to lysosome transport(GO:0008333) |
| 0.0 | 0.1 | GO:0030206 | chondroitin sulfate biosynthetic process(GO:0030206) |
| 0.0 | 0.1 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.0 | 0.7 | GO:0034394 | protein localization to cell surface(GO:0034394) |
| 0.0 | 0.5 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.7 | GO:0048013 | ephrin receptor signaling pathway(GO:0048013) |
| 0.0 | 0.9 | GO:0055013 | cardiac muscle cell development(GO:0055013) |
| 0.0 | 0.2 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.0 | 1.4 | GO:2000045 | regulation of G1/S transition of mitotic cell cycle(GO:2000045) |
| 0.0 | 0.2 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
| 0.0 | 0.2 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.0 | 0.1 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.0 | 0.3 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
| 0.0 | 0.3 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
| 0.0 | 0.3 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.0 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.5 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 0.5 | 1.5 | GO:0045160 | myosin I complex(GO:0045160) |
| 0.5 | 4.9 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.5 | 4.6 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.4 | 4.9 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.3 | 1.4 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.2 | 3.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.2 | 1.0 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.2 | 0.9 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
| 0.2 | 1.6 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.2 | 0.7 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.2 | 2.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.2 | 1.7 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 0.4 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 0.1 | 0.7 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
| 0.1 | 1.5 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.1 | 1.4 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 0.8 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 0.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 0.1 | 1.0 | GO:0031105 | septin complex(GO:0031105) |
| 0.1 | 1.0 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.1 | 0.7 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.1 | 1.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 1.5 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 0.4 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.1 | 0.7 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 7.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 0.7 | GO:0070938 | contractile ring(GO:0070938) |
| 0.1 | 0.4 | GO:0045179 | apical cortex(GO:0045179) |
| 0.1 | 0.6 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 0.8 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.1 | 1.2 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.1 | 0.8 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 2.1 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 1.2 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) |
| 0.0 | 2.0 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 0.6 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.3 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 0.1 | GO:0032311 | angiogenin-PRI complex(GO:0032311) |
| 0.0 | 0.1 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) lumenal side of membrane(GO:0098576) |
| 0.0 | 0.5 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 1.0 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 0.3 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.0 | 0.6 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.3 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 1.3 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 0.6 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.4 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.3 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 0.2 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.4 | GO:0034706 | voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706) |
| 0.0 | 0.3 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 1.1 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.3 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 0.2 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.1 | GO:0043256 | laminin complex(GO:0043256) |
| 0.0 | 0.9 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.3 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.0 | 0.6 | GO:0005776 | autophagosome(GO:0005776) |
| 0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.2 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 0.2 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.1 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.3 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 0.8 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.1 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.0 | 8.5 | GO:0005768 | endosome(GO:0005768) |
| 0.0 | 0.4 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 0.3 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.5 | GO:0030139 | endocytic vesicle(GO:0030139) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.9 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.6 | 2.3 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.4 | 2.4 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.3 | 1.2 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 0.9 | GO:0047751 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 0.3 | 1.9 | GO:0070697 | activin receptor binding(GO:0070697) |
| 0.2 | 1.5 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.2 | 5.2 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.2 | 2.1 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.2 | 1.0 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.2 | 0.6 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.2 | 0.8 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 0.2 | 1.4 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.2 | 2.8 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.2 | 0.6 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.2 | 0.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.2 | 1.2 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.1 | 0.8 | GO:0036435 | K48-linked polyubiquitin binding(GO:0036435) |
| 0.1 | 1.0 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.1 | 3.9 | GO:0034930 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131) |
| 0.1 | 0.6 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.1 | 1.7 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 1.1 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 0.6 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.6 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 0.1 | 0.4 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.1 | 0.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 1.3 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 1.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.8 | GO:0008199 | ferric iron binding(GO:0008199) |
| 0.1 | 0.5 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.1 | 0.8 | GO:0003993 | acid phosphatase activity(GO:0003993) |
| 0.1 | 0.3 | GO:0043912 | D-lysine oxidase activity(GO:0043912) |
| 0.1 | 0.9 | GO:0008113 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) |
| 0.1 | 0.4 | GO:0004090 | carbonyl reductase (NADPH) activity(GO:0004090) |
| 0.1 | 3.6 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.1 | 1.8 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.1 | 0.3 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.1 | 1.1 | GO:0004438 | phosphatidylinositol-3-phosphatase activity(GO:0004438) |
| 0.1 | 0.2 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 0.4 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.1 | 0.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.1 | 0.4 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 1.0 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 0.3 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.1 | 0.2 | GO:0071862 | protein phosphatase type 1 activator activity(GO:0071862) |
| 0.1 | 0.6 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.1 | 0.2 | GO:0046964 | 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964) |
| 0.1 | 0.7 | GO:0034943 | acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409) |
| 0.1 | 0.7 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.1 | 0.5 | GO:0004416 | hydroxyacylglutathione hydrolase activity(GO:0004416) |
| 0.1 | 0.4 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.0 | 1.2 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 3.7 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 2.4 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 1.2 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.0 | 1.7 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.5 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.0 | 0.6 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.5 | GO:0016701 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 0.7 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.6 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.7 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.0 | 1.7 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.7 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.0 | 0.2 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 0.0 | 0.3 | GO:0035014 | retinoic acid binding(GO:0001972) phosphatidylinositol 3-kinase regulator activity(GO:0035014) |
| 0.0 | 0.8 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.0 | 0.7 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 1.1 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 0.2 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.0 | 0.3 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.0 | 0.1 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 1.3 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 0.4 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.2 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.0 | 0.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 0.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 0.6 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.3 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.3 | GO:0050253 | prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032) |
| 0.0 | 2.2 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
| 0.0 | 0.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.3 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 1.2 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 0.1 | GO:0008428 | ribonuclease inhibitor activity(GO:0008428) |
| 0.0 | 0.1 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 1.4 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 0.4 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.2 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 6.7 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.3 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.5 | GO:0002039 | p53 binding(GO:0002039) |
