Motif ID: Insm1

Z-value: 0.364


Transcription factors associated with Insm1:

Gene SymbolEntrez IDGene Name
Insm1 ENSMUSG00000068154.4 Insm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Insm1mm10_v2_chr2_+_146221921_1462219210.396.9e-02Click!


Activity profile for motif Insm1.

activity profile for motif Insm1


Sorted Z-values histogram for motif Insm1

Sorted Z-values for motif Insm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Insm1

PNG image of the network

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Top targets:


Showing 1 to 20 of 124 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_77894096 1.107 ENSMUST00000017597.4
 Pipox
pipecolic acid oxidase
chr12_+_37880700 0.992 ENSMUST00000040500.7
 Dgkb
diacylglycerol kinase, beta
chr16_-_67620880 0.700 ENSMUST00000114292.1
ENSMUST00000120898.1
 Cadm2

cell adhesion molecule 2

chr13_+_16011851 0.624 ENSMUST00000042603.6
 Inhba
inhibin beta-A
chrX_+_99975570 0.610 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
 Eda








ectodysplasin-A








chr16_-_67620805 0.608 ENSMUST00000120594.1
 Cadm2
cell adhesion molecule 2
chr12_-_12940600 0.599 ENSMUST00000130990.1
 Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chrX_+_9199865 0.551 ENSMUST00000069763.2
 Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr10_-_42276688 0.547 ENSMUST00000175881.1
ENSMUST00000056974.3
 Foxo3

forkhead box O3

chr15_-_54919961 0.540 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
 Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr6_+_4902913 0.527 ENSMUST00000175889.1
ENSMUST00000168998.2
 Ppp1r9a

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr2_+_32609043 0.499 ENSMUST00000128811.1
 St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr4_-_88033328 0.488 ENSMUST00000078090.5
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_+_5057161 0.467 ENSMUST00000045543.5
 Ccdc106
coiled-coil domain containing 106
chr3_+_117575268 0.462 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr7_+_5056706 0.455 ENSMUST00000144802.1
 Ccdc106
coiled-coil domain containing 106
chr1_+_36511867 0.450 ENSMUST00000001166.7
ENSMUST00000097776.3
 Cnnm3

cyclin M3

chr3_-_73056943 0.436 ENSMUST00000059407.7
 Slitrk3
SLIT and NTRK-like family, member 3
chr19_+_8664005 0.428 ENSMUST00000035444.3
ENSMUST00000163785.1
 Chrm1

cholinergic receptor, muscarinic 1, CNS

chr2_-_127521358 0.427 ENSMUST00000028850.8
ENSMUST00000103215.4
 Kcnip3

Kv channel interacting protein 3, calsenilin


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.4 1.1 GO:0006553 lysine metabolic process(GO:0006553)
0.0 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 0.9 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 0.9 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 0.6 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.6 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.6 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.5 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.4 GO:1903416 response to glycoside(GO:1903416)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 0.9 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 0.6 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) growth cone filopodium(GO:1990812)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.9 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.5 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116) steroid hormone binding(GO:1990239)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0015288 porin activity(GO:0015288)