Motif ID: Foxq1
Z-value: 1.237
Transcription factors associated with Foxq1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Foxq1 | ENSMUSG00000038415.8 | Foxq1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxq1 | mm10_v2_chr13_+_31558157_31558176 | -0.10 | 6.5e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.5 | 7.6 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 2.2 | 6.5 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 1.9 | 5.6 | GO:0032650 | regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730) interleukin-1 alpha secretion(GO:0050703) |
| 1.2 | 2.4 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.7 | 6.9 | GO:0007379 | segment specification(GO:0007379) |
| 0.6 | 1.8 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 0.6 | 4.1 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.4 | 1.2 | GO:0014826 | vein smooth muscle contraction(GO:0014826) |
| 0.4 | 14.9 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.4 | 4.1 | GO:0042118 | endothelial cell activation(GO:0042118) |
| 0.3 | 4.0 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.3 | 7.6 | GO:0095500 | acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145) |
| 0.2 | 2.1 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.2 | 1.1 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.2 | 1.0 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.2 | 0.4 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 0.2 | 1.2 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.2 | 1.5 | GO:2000301 | myeloid progenitor cell differentiation(GO:0002318) negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.2 | 3.7 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.2 | 0.7 | GO:0071476 | cellular hypotonic response(GO:0071476) |
| 0.2 | 0.6 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.2 | 1.6 | GO:0070574 | cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574) |
| 0.1 | 1.0 | GO:0032196 | transposition(GO:0032196) |
| 0.1 | 0.4 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 0.1 | 1.6 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.1 | 0.9 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 0.6 | GO:0036438 | positive regulation of heterotypic cell-cell adhesion(GO:0034116) maintenance of lens transparency(GO:0036438) |
| 0.1 | 2.6 | GO:0007614 | short-term memory(GO:0007614) |
| 0.1 | 0.9 | GO:2000258 | negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258) |
| 0.1 | 0.9 | GO:0006537 | glutamate biosynthetic process(GO:0006537) proline biosynthetic process(GO:0006561) |
| 0.1 | 1.2 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
| 0.1 | 1.9 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.1 | 0.5 | GO:0008655 | pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) |
| 0.1 | 0.9 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.1 | 0.3 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
| 0.1 | 1.8 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.6 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
| 0.1 | 1.3 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 7.0 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.1 | 0.6 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.0 | 0.1 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.0 | 1.0 | GO:0060074 | synapse maturation(GO:0060074) |
| 0.0 | 0.7 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.0 | 1.6 | GO:0055072 | iron ion homeostasis(GO:0055072) |
| 0.0 | 0.3 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.0 | 0.1 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.0 | 0.2 | GO:0009301 | snRNA transcription(GO:0009301) |
| 0.0 | 1.0 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) |
| 0.0 | 1.0 | GO:0006284 | base-excision repair(GO:0006284) |
| 0.0 | 0.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 1.4 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.8 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.3 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.0 | 4.2 | GO:0006869 | lipid transport(GO:0006869) |
| 0.0 | 0.4 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.1 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
| 0.0 | 3.1 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.0 | 0.6 | GO:0051591 | response to cAMP(GO:0051591) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 7.6 | GO:0000805 | X chromosome(GO:0000805) |
| 0.6 | 6.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.4 | 5.6 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.2 | 1.8 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.2 | 0.6 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.1 | 4.1 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.1 | 6.9 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 0.9 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.1 | 1.2 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 3.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.1 | 1.4 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 0.1 | 0.9 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.0 | 0.9 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 2.4 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.3 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.0 | 0.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.0 | 2.9 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 1.8 | GO:0072686 | mitotic spindle(GO:0072686) |
| 0.0 | 0.3 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 0.3 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 4.3 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 0.3 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 5.1 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 2.3 | GO:0045121 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 1.0 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.7 | GO:0031012 | extracellular matrix(GO:0031012) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 7.9 | GO:0030549 | acetylcholine receptor activator activity(GO:0030549) |
| 1.1 | 6.5 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
| 1.0 | 4.1 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.9 | 5.6 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.5 | 4.1 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.4 | 1.2 | GO:0004962 | endothelin receptor activity(GO:0004962) |
| 0.2 | 3.7 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.2 | 0.6 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
| 0.2 | 1.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 1.0 | GO:0000405 | bubble DNA binding(GO:0000405) |
| 0.2 | 0.9 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.1 | 1.4 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.1 | 0.6 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.1 | 18.5 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 1.2 | GO:0097153 | cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) |
| 0.1 | 0.6 | GO:0050265 | RNA uridylyltransferase activity(GO:0050265) |
| 0.1 | 0.7 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 1.6 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.1 | 2.9 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 0.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.1 | 6.3 | GO:0002039 | p53 binding(GO:0002039) |
| 0.1 | 0.3 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.1 | 0.3 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 7.4 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.0 | 1.5 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.0 | 2.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.0 | 0.9 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.9 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646) |
| 0.0 | 0.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 1.0 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.8 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 2.4 | GO:0003823 | antigen binding(GO:0003823) |
| 0.0 | 0.4 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 1.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 1.1 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 1.2 | GO:0004896 | cytokine receptor activity(GO:0004896) |
| 0.0 | 4.1 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
| 0.0 | 0.6 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.9 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 0.3 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 0.2 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.0 | 0.4 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 0.8 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.0 | 0.4 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 0.1 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
