Motif ID: Hoxd8

Z-value: 0.555


Transcription factors associated with Hoxd8:

Gene SymbolEntrez IDGene Name
Hoxd8 ENSMUSG00000027102.4 Hoxd8



Activity profile for motif Hoxd8.

activity profile for motif Hoxd8


Sorted Z-values histogram for motif Hoxd8

Sorted Z-values for motif Hoxd8



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd8

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_140671400 1.124 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr2_-_140671462 1.008 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chr6_+_34384218 0.755 ENSMUST00000038383.7
ENSMUST00000115051.1
Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

chr9_+_80165013 0.683 ENSMUST00000035889.8
ENSMUST00000113268.1
Myo6

myosin VI

chr11_+_16257706 0.635 ENSMUST00000109645.2
ENSMUST00000109647.2
Vstm2a

V-set and transmembrane domain containing 2A

chr6_+_71282280 0.597 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr9_+_80165079 0.551 ENSMUST00000184480.1
Myo6
myosin VI
chr3_-_116712644 0.490 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr5_-_111761697 0.486 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
E130006D01Rik


RIKEN cDNA E130006D01 gene


chr1_+_178798438 0.412 ENSMUST00000160789.1
Kif26b
kinesin family member 26B
chr8_+_34054622 0.405 ENSMUST00000149618.1
Gm9951
predicted gene 9951
chr15_-_35155750 0.396 ENSMUST00000067033.7
ENSMUST00000018476.7
Stk3

serine/threonine kinase 3

chr3_+_127633134 0.395 ENSMUST00000029587.7
Neurog2
neurogenin 2
chr5_+_107497718 0.394 ENSMUST00000112671.2
A830010M20Rik
RIKEN cDNA A830010M20 gene
chr1_-_172027269 0.370 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr11_+_117809687 0.347 ENSMUST00000120928.1
ENSMUST00000175737.1
Syngr2

synaptogyrin 2

chr17_-_32822200 0.336 ENSMUST00000179695.1
Zfp799
zinc finger protein 799
chr2_-_66410064 0.320 ENSMUST00000112366.1
Scn1a
sodium channel, voltage-gated, type I, alpha
chr1_-_158814469 0.316 ENSMUST00000161589.2
Pappa2
pappalysin 2
chr7_+_39588931 0.314 ENSMUST00000178791.1
ENSMUST00000098511.3
Gm2058

predicted gene 2058

chr3_+_76075583 0.296 ENSMUST00000160261.1
Fstl5
follistatin-like 5
chr2_-_177267036 0.266 ENSMUST00000108963.1
Gm14409
predicted gene 14409
chr5_-_62766153 0.259 ENSMUST00000076623.4
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr12_-_90969768 0.238 ENSMUST00000181184.1
4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr9_-_15301555 0.236 ENSMUST00000034414.8
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr2_-_73580288 0.229 ENSMUST00000028515.3
Chrna1
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr1_-_126830632 0.227 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr2_-_160619971 0.220 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr11_+_117809653 0.212 ENSMUST00000026649.7
ENSMUST00000177131.1
ENSMUST00000132298.1
Syngr2

Gm20708
synaptogyrin 2

predicted gene 20708
chr4_-_132398199 0.205 ENSMUST00000136711.1
ENSMUST00000084249.4
Phactr4

phosphatase and actin regulator 4

chr10_+_58394361 0.201 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr1_+_178405881 0.191 ENSMUST00000027775.7
Efcab2
EF-hand calcium binding domain 2
chr8_+_40354303 0.187 ENSMUST00000136835.1
Micu3
mitochondrial calcium uptake family, member 3
chr16_+_11406618 0.180 ENSMUST00000122168.1
Snx29
sorting nexin 29
chr7_-_99980431 0.178 ENSMUST00000080817.4
Rnf169
ring finger protein 169
chr5_-_73191848 0.175 ENSMUST00000176910.1
Fryl
furry homolog-like (Drosophila)
chr7_-_80405425 0.172 ENSMUST00000107362.3
ENSMUST00000135306.1
Furin

furin (paired basic amino acid cleaving enzyme)

chr13_-_85127514 0.167 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr12_+_72536342 0.167 ENSMUST00000044352.6
Pcnxl4
pecanex-like 4 (Drosophila)
chr2_+_110597298 0.164 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr4_+_118961578 0.160 ENSMUST00000058651.4
Lao1
L-amino acid oxidase 1
chr12_-_12940600 0.156 ENSMUST00000130990.1
Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr10_+_103367748 0.155 ENSMUST00000074204.4
ENSMUST00000179636.1
Slc6a15

solute carrier family 6 (neurotransmitter transporter), member 15

chr9_+_54538984 0.146 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7

SH2 domain containing 7

chr9_-_55512156 0.146 ENSMUST00000034866.8
Etfa
electron transferring flavoprotein, alpha polypeptide
chr12_-_84617326 0.144 ENSMUST00000021666.4
Abcd4
ATP-binding cassette, sub-family D (ALD), member 4
chr17_+_74489492 0.137 ENSMUST00000024873.6
Yipf4
Yip1 domain family, member 4
chr2_-_163472561 0.134 ENSMUST00000109418.1
Fitm2
fat storage-inducing transmembrane protein 2
chrX_-_160138375 0.134 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr3_+_10088173 0.127 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chr2_+_83724397 0.122 ENSMUST00000028499.4
ENSMUST00000141725.1
ENSMUST00000111740.2
Itgav


integrin alpha V


chr1_-_126830786 0.113 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chr10_+_97482350 0.108 ENSMUST00000163448.2
Dcn
decorin
chr14_+_47298260 0.108 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chr4_-_108301045 0.104 ENSMUST00000043616.6
Zyg11b
zyg-ll family member B, cell cycle regulator
chr18_-_73754457 0.104 ENSMUST00000041138.2
Elac1
elaC homolog 1 (E. coli)
chr7_-_29906524 0.099 ENSMUST00000159920.1
ENSMUST00000162592.1
Zfp27

zinc finger protein 27

chr2_+_152669461 0.096 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
H13



histocompatibility 13



chrX_-_74393003 0.091 ENSMUST00000015427.6
Fam3a
family with sequence similarity 3, member A
chr14_+_55560010 0.090 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr5_+_24394388 0.087 ENSMUST00000115074.1
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr19_-_33761949 0.087 ENSMUST00000025694.6
ENSMUST00000147153.1
Lipo1
Lipo2
lipase, member O1
lipase, member O2
chr10_-_76110956 0.082 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr4_+_101986626 0.075 ENSMUST00000106914.1
Gm12789
predicted gene 12789
chr7_+_126976338 0.060 ENSMUST00000032920.3
Cdipt
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr3_-_19264959 0.060 ENSMUST00000121951.1
Pde7a
phosphodiesterase 7A
chr5_+_48372363 0.054 ENSMUST00000030968.2
Pacrgl
PARK2 co-regulated-like
chr18_+_60774675 0.045 ENSMUST00000118551.1
Rps14
ribosomal protein S14
chr5_-_38491948 0.044 ENSMUST00000129099.1
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr10_-_127030813 0.042 ENSMUST00000040560.4
Tsfm
Ts translation elongation factor, mitochondrial
chr10_+_75037291 0.040 ENSMUST00000139384.1
Rab36
RAB36, member RAS oncogene family
chr3_-_19265007 0.038 ENSMUST00000091314.4
Pde7a
phosphodiesterase 7A
chr14_+_55559993 0.035 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr10_-_127030789 0.027 ENSMUST00000120547.1
ENSMUST00000152054.1
Tsfm

Ts translation elongation factor, mitochondrial

chr8_-_84662841 0.026 ENSMUST00000060427.4
Ier2
immediate early response 2
chr7_+_140763739 0.022 ENSMUST00000026552.7
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr2_+_152687137 0.010 ENSMUST00000062148.6
Mcts2
malignant T cell amplified sequence 2
chr2_+_36230426 0.008 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr15_+_81744848 0.006 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chr5_-_31295862 0.003 ENSMUST00000041266.7
ENSMUST00000172435.1
Fndc4

fibronectin type III domain containing 4

chr14_+_58893465 0.001 ENSMUST00000079960.1
Rpl13-ps3
ribosomal protein L13, pseudogene 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.4 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.4 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.5 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 1.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.2 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.2 GO:2000780 negative regulation of double-strand break repair(GO:2000780)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 1.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.0 2.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0052650 retinal binding(GO:0016918) NADP-retinol dehydrogenase activity(GO:0052650)
0.1 2.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.2 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
0.1 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.0 0.6 GO:0005402 cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)