Motif ID: Grhl1

Z-value: 0.447


Transcription factors associated with Grhl1:

Gene SymbolEntrez IDGene Name
Grhl1 ENSMUSG00000020656.9 Grhl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Grhl1mm10_v2_chr12_+_24572276_24572308-0.135.5e-01Click!


Activity profile for motif Grhl1.

activity profile for motif Grhl1


Sorted Z-values histogram for motif Grhl1

Sorted Z-values for motif Grhl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Grhl1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_85722474 1.082 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr14_-_57133268 0.629 ENSMUST00000160703.1
 Gjb6
gap junction protein, beta 6
chrX_-_38456407 0.530 ENSMUST00000074913.5
ENSMUST00000016678.7
ENSMUST00000061755.8
 Lamp2


lysosomal-associated membrane protein 2


chr3_-_87263518 0.508 ENSMUST00000090986.4
 Fcrls
Fc receptor-like S, scavenger receptor
chr14_+_63943666 0.464 ENSMUST00000079652.5
 Sox7
SRY-box containing gene 7
chr4_+_155086577 0.462 ENSMUST00000030915.4
ENSMUST00000155775.1
ENSMUST00000127457.1
 Morn1


MORN repeat containing 1


chr1_-_192855723 0.449 ENSMUST00000155579.1
 Sertad4
SERTA domain containing 4
chr2_+_149830840 0.406 ENSMUST00000109934.1
ENSMUST00000140870.1
 Syndig1

synapse differentiation inducing 1

chr3_-_87263703 0.403 ENSMUST00000146512.1
 Fcrls
Fc receptor-like S, scavenger receptor
chr17_-_56005566 0.396 ENSMUST00000043785.6
 Stap2
signal transducing adaptor family member 2
chr8_-_71381907 0.379 ENSMUST00000002466.8
 Nr2f6
nuclear receptor subfamily 2, group F, member 6
chrX_+_100730178 0.377 ENSMUST00000113744.1
 Gdpd2
glycerophosphodiester phosphodiesterase domain containing 2
chr17_+_87635974 0.357 ENSMUST00000053577.8
 Epcam
epithelial cell adhesion molecule
chr2_+_149830788 0.346 ENSMUST00000109935.1
 Syndig1
synapse differentiation inducing 1
chr18_+_56432116 0.338 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr17_+_43389436 0.325 ENSMUST00000113599.1
 Gpr116
G protein-coupled receptor 116
chr7_+_101321703 0.315 ENSMUST00000174291.1
ENSMUST00000167888.2
ENSMUST00000172662.1
ENSMUST00000173270.1
ENSMUST00000174083.1
 Stard10




START domain containing 10




chr2_+_149830894 0.277 ENSMUST00000137280.1
ENSMUST00000149705.1
 Syndig1

synapse differentiation inducing 1

chr14_+_75136326 0.273 ENSMUST00000145303.1
 Lcp1
lymphocyte cytosolic protein 1
chr16_-_26989974 0.265 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr12_+_76417598 0.256 ENSMUST00000063977.7
 Ppp1r36
protein phosphatase 1, regulatory subunit 36
chr14_+_79481164 0.245 ENSMUST00000040131.5
 Elf1
E74-like factor 1
chr14_-_79481268 0.208 ENSMUST00000022601.5
 Wbp4
WW domain binding protein 4
chr2_-_30205772 0.194 ENSMUST00000113662.1
 Ccbl1
cysteine conjugate-beta lyase 1
chr2_-_30205794 0.186 ENSMUST00000113663.2
ENSMUST00000044038.3
 Ccbl1

cysteine conjugate-beta lyase 1

chr7_+_12927410 0.183 ENSMUST00000045870.4
 2310014L17Rik
RIKEN cDNA 2310014L17 gene
chr9_+_21337828 0.174 ENSMUST00000034697.7
 Slc44a2
solute carrier family 44, member 2
chr9_+_15239045 0.166 ENSMUST00000034413.6
 Vstm5
V-set and transmembrane domain containing 5
chr18_-_25753852 0.160 ENSMUST00000025117.6
ENSMUST00000115816.2
 Celf4

CUGBP, Elav-like family member 4

chr17_-_34628380 0.160 ENSMUST00000167097.2
 Ppt2
palmitoyl-protein thioesterase 2
chr17_-_34628005 0.138 ENSMUST00000166040.2
 Ppt2
palmitoyl-protein thioesterase 2
chr19_+_18631927 0.127 ENSMUST00000159572.1
ENSMUST00000042392.7
 Nmrk1

nicotinamide riboside kinase 1

chr12_-_54656496 0.125 ENSMUST00000056228.6
 Sptssa
serine palmitoyltransferase, small subunit A
chr7_+_65693417 0.117 ENSMUST00000032726.7
ENSMUST00000107495.3
 Tm2d3

TM2 domain containing 3

chr12_-_20900867 0.112 ENSMUST00000079237.5
 Zfp125
zinc finger protein 125
chr4_+_141242850 0.105 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
 Arhgef19


Rho guanine nucleotide exchange factor (GEF) 19


chr7_-_45333754 0.096 ENSMUST00000042194.8
 Trpm4
transient receptor potential cation channel, subfamily M, member 4
chr4_-_155086271 0.090 ENSMUST00000030914.3
 Rer1
RER1 retention in endoplasmic reticulum 1 homolog (S. cerevisiae)
chr4_+_108834601 0.086 ENSMUST00000030296.8
 Txndc12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr14_-_73385225 0.084 ENSMUST00000022704.7
 Itm2b
integral membrane protein 2B
chr4_-_19570073 0.081 ENSMUST00000029885.4
 Cpne3
copine III
chr18_-_46280820 0.073 ENSMUST00000025354.3
 Pggt1b
protein geranylgeranyltransferase type I, beta subunit
chr9_-_7872983 0.054 ENSMUST00000115672.1
 Birc3
baculoviral IAP repeat-containing 3
chr9_-_44268156 0.054 ENSMUST00000169651.1
 Nlrx1
NLR family member X1
chr12_-_69893162 0.048 ENSMUST00000049239.7
ENSMUST00000110570.1
 Map4k5

mitogen-activated protein kinase kinase kinase kinase 5

chr2_-_30967859 0.015 ENSMUST00000028200.8
 Tor1a
torsin family 1, member A (torsin A)
chr2_-_105399286 0.015 ENSMUST00000006128.6
 Rcn1
reticulocalbin 1
chr17_+_29268788 0.006 ENSMUST00000064709.5
ENSMUST00000120346.1
 BC004004

cDNA sequence BC004004

chr17_-_65884902 0.005 ENSMUST00000024905.9
 Ralbp1
ralA binding protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 1.0 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 0.5 GO:0061684 chaperone-mediated autophagy(GO:0061684)
0.0 0.3 GO:0032782 bile acid secretion(GO:0032782) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.4 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.2 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.5 GO:0001706 endoderm formation(GO:0001706)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.0 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 1.0 GO:0035254 glutamate receptor binding(GO:0035254)