Motif ID: Hdx

Z-value: 6.532


Transcription factors associated with Hdx:

Gene SymbolEntrez IDGene Name
Hdx ENSMUSG00000034551.6 Hdx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hdxmm10_v2_chrX_-_111697069_1116971270.213.3e-01Click!


Activity profile for motif Hdx.

activity profile for motif Hdx


Sorted Z-values histogram for motif Hdx

Sorted Z-values for motif Hdx



Network of associatons between targets according to the STRING database.



First level regulatory network of Hdx

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_3017408 170.205 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr9_+_3015654 139.500 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr9_+_3023547 138.844 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr9_+_3000922 121.838 ENSMUST00000151376.2
Gm10722
predicted gene 10722
chr9_+_3027439 119.096 ENSMUST00000177875.1
ENSMUST00000179982.1
Gm10717

predicted gene 10717

chr9_+_3005125 112.701 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr9_+_3034599 110.753 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr9_+_3025417 98.901 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr14_-_19418930 92.659 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr9_+_3018753 77.688 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr9_+_3036877 73.646 ENSMUST00000155807.2
Gm10715
predicted gene 10715
chr9_+_3004457 70.190 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr9_+_3037111 68.978 ENSMUST00000177969.1
Gm10715
predicted gene 10715
chr9_+_3013140 67.322 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr2_-_98667264 52.591 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr6_-_143947092 3.830 ENSMUST00000144289.1
ENSMUST00000111748.1
Sox5

SRY-box containing gene 5

chr6_-_143947061 3.770 ENSMUST00000124233.1
Sox5
SRY-box containing gene 5
chr4_-_149126688 3.546 ENSMUST00000030815.2
Cort
cortistatin
chr11_-_109472611 3.006 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr8_+_84415348 2.918 ENSMUST00000121390.1
ENSMUST00000122053.1
Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chrX_+_164373363 2.556 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr17_+_3397189 2.548 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr12_-_27160311 2.534 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866


predicted gene 9866


chr7_+_66839726 2.492 ENSMUST00000098382.3
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr5_+_107437908 2.315 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr7_+_66839752 2.212 ENSMUST00000107478.1
Adamts17
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 17
chr11_+_69765970 2.000 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr2_-_165368723 1.893 ENSMUST00000141140.1
ENSMUST00000103085.1
Zfp663

zinc finger protein 663

chr7_+_19359740 1.834 ENSMUST00000140836.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr9_+_53771499 1.827 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr4_-_82850721 1.774 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr11_-_69369377 1.704 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3

chromodomain helicase DNA binding protein 3

chr18_+_37477768 1.655 ENSMUST00000051442.5
Pcdhb16
protocadherin beta 16
chr1_+_87327044 1.337 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr14_-_68655804 1.332 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28

a disintegrin and metallopeptidase domain 28

chr4_-_133498538 1.304 ENSMUST00000125541.1
Trnp1
TMF1-regulated nuclear protein 1
chr4_-_115133977 1.204 ENSMUST00000051400.7
Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
chr5_+_90794530 1.202 ENSMUST00000031322.6
Cxcl15
chemokine (C-X-C motif) ligand 15
chrX_+_143518671 1.166 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr1_+_87327008 1.113 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2

GRB10 interacting GYF protein 2

chr10_+_127420334 1.093 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chrX_-_21089229 1.022 ENSMUST00000040667.6
Zfp300
zinc finger protein 300
chrX_-_145505175 0.995 ENSMUST00000143610.1
Amot
angiomotin
chr17_+_31433054 0.978 ENSMUST00000136384.1
Pde9a
phosphodiesterase 9A
chrX_-_143827391 0.951 ENSMUST00000087316.5
Capn6
calpain 6
chr6_-_149101506 0.925 ENSMUST00000127727.1
Dennd5b
DENN/MADD domain containing 5B
chr1_+_180101144 0.829 ENSMUST00000133890.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr12_-_87775755 0.786 ENSMUST00000164517.2
Gm21319
predicted gene, 21319
chr16_-_50432340 0.768 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx




bobby sox homolog (Drosophila)




chr14_-_19977040 0.703 ENSMUST00000159028.1
Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr9_+_45055166 0.613 ENSMUST00000114664.1
ENSMUST00000093856.3
Mpzl3

myelin protein zero-like 3

chr14_+_115092244 0.599 ENSMUST00000176912.1
ENSMUST00000175665.1
Gpc5

glypican 5

chr13_-_67269068 0.578 ENSMUST00000045969.7
Zfp458
zinc finger protein 458
chr11_-_76509419 0.556 ENSMUST00000094012.4
Abr
active BCR-related gene
chr14_-_19977151 0.534 ENSMUST00000055100.7
ENSMUST00000162425.1
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr17_+_17402672 0.466 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr14_-_36968679 0.466 ENSMUST00000067700.6
Ccser2
coiled-coil serine rich 2
chr5_-_129879038 0.441 ENSMUST00000026617.6
Phkg1
phosphorylase kinase gamma 1
chr14_+_70774304 0.422 ENSMUST00000022698.7
Dok2
docking protein 2
chr1_-_172027251 0.403 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr5_-_107597533 0.392 ENSMUST00000124140.1
Glmn
glomulin, FKBP associated protein
chr7_+_113513854 0.343 ENSMUST00000067929.8
ENSMUST00000129087.1
ENSMUST00000164745.1
ENSMUST00000136158.1
Far1



fatty acyl CoA reductase 1



chrX_+_164419782 0.339 ENSMUST00000033754.7
Piga
phosphatidylinositol glycan anchor biosynthesis, class A
chr13_+_24327415 0.307 ENSMUST00000167746.1
Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr8_-_84773381 0.292 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr15_+_100761741 0.248 ENSMUST00000023776.6
Slc4a8
solute carrier family 4 (anion exchanger), member 8
chr8_-_54718664 0.240 ENSMUST00000144711.2
ENSMUST00000093510.2
Wdr17

WD repeat domain 17

chr1_+_180109192 0.179 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa

CDC42 binding protein kinase alpha

chr4_+_43406435 0.077 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2

RUN and SH3 domain containing 2

chr11_+_115765420 0.066 ENSMUST00000093912.4
ENSMUST00000136720.1
ENSMUST00000103034.3
ENSMUST00000141871.1
2310067B10Rik



RIKEN cDNA 2310067B10 gene




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.6 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
1.0 2.9 GO:0050883 musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 1.0 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.2 2.8 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.2 1.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 3.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.4 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 1.8 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.1 0.3 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.1 1.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.3 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 2.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 1073.0 GO:0008150 biological_process(GO:0008150)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.1 2.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 1.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1084.5 GO:0005575 cellular_component(GO:0005575)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0043532 angiostatin binding(GO:0043532)
0.2 1.2 GO:0070330 aromatase activity(GO:0070330)
0.2 2.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 3.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 0.3 GO:0050062 long-chain-fatty-acyl-CoA reductase activity(GO:0050062) fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1087.7 GO:0003674 molecular_function(GO:0003674)