Motif ID: Epas1_Bcl3
Z-value: 1.356
Transcription factors associated with Epas1_Bcl3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bcl3 | ENSMUSG00000053175.10 | Bcl3 |
| Epas1 | ENSMUSG00000024140.9 | Epas1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Epas1 | mm10_v2_chr17_+_86753900_86753914 | -0.40 | 5.8e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 3.1 | GO:0055095 | lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) |
| 0.7 | 2.2 | GO:0098528 | terpenoid catabolic process(GO:0016115) skeletal muscle fiber differentiation(GO:0098528) |
| 0.7 | 1.4 | GO:0072076 | nephrogenic mesenchyme development(GO:0072076) |
| 0.7 | 3.5 | GO:0071205 | clustering of voltage-gated potassium channels(GO:0045163) protein localization to juxtaparanode region of axon(GO:0071205) |
| 0.6 | 2.5 | GO:0003360 | brainstem development(GO:0003360) |
| 0.6 | 1.8 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 0.6 | 1.8 | GO:1901731 | calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731) |
| 0.6 | 4.0 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.6 | 3.3 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.5 | 2.1 | GO:0010838 | positive regulation of keratinocyte proliferation(GO:0010838) |
| 0.5 | 3.2 | GO:1902866 | regulation of retina development in camera-type eye(GO:1902866) |
| 0.5 | 4.5 | GO:0048170 | positive regulation of long-term neuronal synaptic plasticity(GO:0048170) |
| 0.5 | 1.9 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.4 | 1.3 | GO:0045659 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 0.4 | 1.3 | GO:0046022 | regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022) |
| 0.4 | 1.3 | GO:0070844 | misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846) |
| 0.4 | 1.2 | GO:0045819 | positive regulation of glycogen catabolic process(GO:0045819) |
| 0.4 | 1.2 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.4 | 1.9 | GO:0001778 | plasma membrane repair(GO:0001778) |
| 0.4 | 1.1 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 0.4 | 2.5 | GO:0033563 | dorsal/ventral axon guidance(GO:0033563) |
| 0.3 | 1.4 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.3 | 1.0 | GO:0030070 | insulin processing(GO:0030070) |
| 0.3 | 1.6 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.3 | 4.6 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
| 0.3 | 0.9 | GO:0010958 | regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963) |
| 0.3 | 2.0 | GO:1900116 | sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116) |
| 0.3 | 1.6 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.3 | 2.3 | GO:0071493 | cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399) |
| 0.3 | 1.0 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.2 | 1.7 | GO:0003011 | involuntary skeletal muscle contraction(GO:0003011) |
| 0.2 | 0.9 | GO:0043973 | histone H3-K4 acetylation(GO:0043973) |
| 0.2 | 0.4 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.2 | 1.5 | GO:0051798 | positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798) |
| 0.2 | 1.8 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.2 | 0.6 | GO:0045085 | negative regulation of interleukin-2 biosynthetic process(GO:0045085) |
| 0.2 | 1.6 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 0.2 | 0.8 | GO:0009957 | epidermal cell fate specification(GO:0009957) |
| 0.2 | 8.1 | GO:1901381 | positive regulation of potassium ion transmembrane transport(GO:1901381) |
| 0.2 | 2.2 | GO:0038166 | angiotensin-activated signaling pathway(GO:0038166) |
| 0.2 | 2.9 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
| 0.2 | 3.2 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.2 | 0.7 | GO:0045162 | clustering of voltage-gated sodium channels(GO:0045162) |
| 0.2 | 2.4 | GO:0006857 | oligopeptide transport(GO:0006857) |
| 0.2 | 0.5 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.2 | 2.8 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.2 | 0.5 | GO:0070649 | formin-nucleated actin cable assembly(GO:0070649) |
| 0.2 | 0.3 | GO:0061043 | regulation of vascular wound healing(GO:0061043) |
| 0.1 | 0.6 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) |
| 0.1 | 0.1 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.1 | 1.9 | GO:0030178 | negative regulation of Wnt signaling pathway(GO:0030178) |
| 0.1 | 2.3 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.1 | 0.6 | GO:0034436 | glycoprotein transport(GO:0034436) |
| 0.1 | 4.5 | GO:0007200 | phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200) |
| 0.1 | 0.3 | GO:0006682 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 1.3 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.1 | 1.5 | GO:0033623 | regulation of integrin activation(GO:0033623) |
| 0.1 | 1.1 | GO:0090232 | positive regulation of spindle checkpoint(GO:0090232) |
| 0.1 | 0.4 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.1 | 2.3 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 0.8 | GO:0014068 | positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068) |
| 0.1 | 0.3 | GO:0006566 | threonine metabolic process(GO:0006566) |
| 0.1 | 0.7 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.1 | 2.2 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.1 | 0.3 | GO:1900126 | negative regulation of hyaluronan biosynthetic process(GO:1900126) |
| 0.1 | 0.5 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.1 | 0.4 | GO:0072539 | T-helper 17 cell differentiation(GO:0072539) |
| 0.1 | 0.3 | GO:1902277 | negative regulation of pancreatic amylase secretion(GO:1902277) |
| 0.1 | 0.6 | GO:0034284 | response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284) |
| 0.1 | 0.4 | GO:0090209 | negative regulation of triglyceride metabolic process(GO:0090209) |
| 0.1 | 2.8 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.1 | 6.1 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.1 | 0.2 | GO:0061537 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 0.1 | 0.4 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
| 0.1 | 1.7 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.1 | 0.3 | GO:0071105 | response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105) |
| 0.1 | 3.0 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
| 0.1 | 0.3 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.1 | 0.3 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.1 | 0.3 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.1 | 0.5 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
| 0.1 | 0.7 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.1 | 1.3 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.1 | 0.5 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) mitotic DNA replication checkpoint(GO:0033314) |
| 0.1 | 0.4 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
| 0.1 | 3.6 | GO:0022900 | electron transport chain(GO:0022900) |
| 0.1 | 2.5 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
| 0.1 | 0.4 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.0 | 1.0 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
| 0.0 | 0.7 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.0 | 1.0 | GO:0045663 | positive regulation of myoblast differentiation(GO:0045663) |
| 0.0 | 0.5 | GO:0006654 | phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473) |
| 0.0 | 0.4 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.0 | 0.3 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 0.0 | 0.2 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
| 0.0 | 0.5 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.0 | 1.1 | GO:0042551 | neuron maturation(GO:0042551) |
| 0.0 | 0.6 | GO:0061000 | negative regulation of dendritic spine development(GO:0061000) |
| 0.0 | 2.9 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.2 | GO:0032423 | regulation of mismatch repair(GO:0032423) |
| 0.0 | 0.4 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.0 | 0.1 | GO:1902897 | regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of dendritic spine maintenance(GO:1902950) positive regulation of dendritic spine maintenance(GO:1902952) |
| 0.0 | 0.3 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.0 | 0.3 | GO:0036506 | maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378) |
| 0.0 | 0.1 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
| 0.0 | 0.1 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.0 | 0.2 | GO:0001975 | response to amphetamine(GO:0001975) response to amine(GO:0014075) cellular response to zinc ion(GO:0071294) |
| 0.0 | 0.1 | GO:0015819 | lysine transport(GO:0015819) |
| 0.0 | 0.1 | GO:0032227 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) |
| 0.0 | 2.5 | GO:0009142 | nucleoside triphosphate biosynthetic process(GO:0009142) |
| 0.0 | 0.2 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.0 | 0.7 | GO:0010955 | negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318) |
| 0.0 | 0.2 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 0.0 | 0.2 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.0 | 0.5 | GO:0009409 | response to cold(GO:0009409) |
| 0.0 | 0.3 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.0 | 0.5 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.2 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.0 | 0.5 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
| 0.0 | 0.1 | GO:0006788 | heme oxidation(GO:0006788) |
| 0.0 | 0.4 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.2 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
| 0.0 | 0.4 | GO:0060348 | bone development(GO:0060348) |
| 0.0 | 0.2 | GO:0050765 | negative regulation of phagocytosis(GO:0050765) |
| 0.0 | 0.0 | GO:0075136 | response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136) |
| 0.0 | 0.4 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.1 | GO:2000301 | negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.0 | 0.4 | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading(GO:1900026) |
| 0.0 | 0.2 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.0 | 0.1 | GO:0042346 | positive regulation of NF-kappaB import into nucleus(GO:0042346) |
| 0.0 | 0.2 | GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844) |
| 0.0 | 0.1 | GO:0001731 | formation of translation preinitiation complex(GO:0001731) |
| 0.0 | 0.2 | GO:0032402 | melanosome transport(GO:0032402) |
| 0.0 | 0.1 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.0 | 0.6 | GO:0003073 | regulation of systemic arterial blood pressure(GO:0003073) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.5 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.8 | 2.3 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
| 0.5 | 1.8 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.4 | 2.1 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.4 | 1.8 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.3 | 1.6 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.3 | 1.6 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.3 | 1.9 | GO:0038037 | G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648) |
| 0.3 | 4.0 | GO:0043196 | varicosity(GO:0043196) |
| 0.3 | 2.3 | GO:0031988 | membrane-bounded vesicle(GO:0031988) |
| 0.2 | 1.0 | GO:0048787 | presynaptic active zone membrane(GO:0048787) |
| 0.2 | 1.9 | GO:0032009 | early phagosome(GO:0032009) |
| 0.2 | 1.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.2 | 3.5 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 0.1 | 0.4 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
| 0.1 | 1.0 | GO:0042627 | chylomicron(GO:0042627) |
| 0.1 | 0.3 | GO:0031523 | Myb complex(GO:0031523) |
| 0.1 | 2.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 0.7 | GO:0008091 | spectrin(GO:0008091) |
| 0.1 | 4.2 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 2.3 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.6 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 0.6 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.1 | 7.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 3.2 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 0.8 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 0.5 | GO:0097449 | astrocyte projection(GO:0097449) |
| 0.1 | 0.3 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 0.4 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 0.1 | GO:0005673 | transcription factor TFIIE complex(GO:0005673) |
| 0.0 | 0.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 5.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.3 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.0 | 1.3 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 2.3 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.4 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 1.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 0.4 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.0 | 0.3 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.0 | 0.3 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 1.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 8.0 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 0.2 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.0 | 1.0 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 3.2 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 0.3 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 0.7 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 3.7 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 0.2 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.0 | 0.1 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 0.5 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.0 | 1.5 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 1.6 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.2 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.0 | 0.2 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.8 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.4 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.4 | GO:0016592 | mediator complex(GO:0016592) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.6 | GO:0022865 | transmembrane electron transfer carrier(GO:0022865) |
| 0.7 | 2.1 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.7 | 2.1 | GO:0005219 | ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763) |
| 0.6 | 3.1 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.6 | 2.8 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) |
| 0.6 | 2.2 | GO:0098988 | PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled glutamate receptor activity(GO:0098988) |
| 0.6 | 3.3 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.5 | 2.8 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.4 | 2.5 | GO:0004897 | ciliary neurotrophic factor receptor activity(GO:0004897) |
| 0.4 | 2.5 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.4 | 1.2 | GO:0000402 | open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402) |
| 0.4 | 1.2 | GO:0031752 | D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752) |
| 0.4 | 1.1 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.4 | 1.9 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.3 | 2.4 | GO:0015198 | oligopeptide transporter activity(GO:0015198) |
| 0.3 | 4.0 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.3 | 2.5 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.3 | 1.3 | GO:0042903 | tubulin deacetylase activity(GO:0042903) |
| 0.3 | 2.0 | GO:0036122 | BMP binding(GO:0036122) |
| 0.3 | 0.8 | GO:0005119 | smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) hedgehog family protein binding(GO:0097108) |
| 0.2 | 2.2 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.2 | 2.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.2 | 4.4 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.2 | 2.4 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.2 | 0.6 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437) |
| 0.2 | 1.3 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.2 | 0.6 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.2 | 1.6 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.2 | 1.6 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.2 | 2.3 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.2 | 1.5 | GO:0048185 | activin binding(GO:0048185) |
| 0.1 | 0.9 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.1 | 0.8 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.1 | 0.9 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.1 | 8.3 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.1 | 0.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 0.4 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 1.0 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 0.4 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.1 | 0.3 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.1 | 3.8 | GO:0045182 | translation regulator activity(GO:0045182) |
| 0.1 | 1.8 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.1 | 1.5 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 2.2 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.1 | 0.9 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.1 | 0.3 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) |
| 0.1 | 3.5 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.1 | 0.8 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 1.3 | GO:0055106 | ubiquitin-protein transferase regulator activity(GO:0055106) |
| 0.1 | 4.7 | GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding(GO:0005546) |
| 0.1 | 0.2 | GO:0005006 | epidermal growth factor-activated receptor activity(GO:0005006) |
| 0.1 | 1.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.1 | 2.8 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 0.7 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 0.3 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 1.4 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.1 | 3.1 | GO:0008146 | sulfotransferase activity(GO:0008146) |
| 0.1 | 0.2 | GO:0030249 | cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249) |
| 0.1 | 0.6 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 2.5 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 0.5 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.1 | 0.9 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.0 | 0.1 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.0 | 1.6 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 1.9 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
| 0.0 | 1.2 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.2 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.0 | 0.2 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.0 | 0.1 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.0 | 0.8 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.0 | 5.6 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.0 | 3.6 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.1 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.0 | 0.2 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.0 | 0.1 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.0 | 0.2 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.0 | 2.1 | GO:0035250 | UDP-galactosyltransferase activity(GO:0035250) |
| 0.0 | 0.4 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.3 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 0.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.1 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) |
| 0.0 | 0.6 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 0.7 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 2.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.2 | GO:0005131 | growth hormone receptor binding(GO:0005131) |
| 0.0 | 0.3 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.6 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.2 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.0 | 0.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 1.3 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.1 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.0 | 0.3 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.1 | GO:0015189 | L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189) |
| 0.0 | 0.5 | GO:0022839 | ion gated channel activity(GO:0022839) |
| 0.0 | 1.3 | GO:0008237 | metallopeptidase activity(GO:0008237) |
| 0.0 | 0.1 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 0.0 | 0.8 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 0.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.2 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.6 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.2 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.1 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 0.9 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 1.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.9 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.1 | GO:0061505 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.0 | 0.2 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
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