Motif ID: Nkx2-3

Z-value: 0.849


Transcription factors associated with Nkx2-3:

Gene SymbolEntrez IDGene Name
Nkx2-3 ENSMUSG00000044220.12 Nkx2-3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nkx2-3mm10_v2_chr19_+_43612299_436123250.048.6e-01Click!


Activity profile for motif Nkx2-3.

activity profile for motif Nkx2-3


Sorted Z-values histogram for motif Nkx2-3

Sorted Z-values for motif Nkx2-3



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_38783503 13.459 ENSMUST00000159334.1
Etv1
ets variant gene 1
chr12_+_38783455 10.812 ENSMUST00000161980.1
ENSMUST00000160701.1
Etv1

ets variant gene 1

chr6_-_23248264 8.517 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr5_+_139543889 4.773 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr10_-_6980376 4.612 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr12_+_38780817 4.157 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr12_+_38780284 4.044 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr1_+_6730051 3.922 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr1_+_6734827 3.825 ENSMUST00000139838.1
St18
suppression of tumorigenicity 18
chr2_+_136057927 3.486 ENSMUST00000057503.6
Lamp5
lysosomal-associated membrane protein family, member 5
chr6_+_34354119 3.120 ENSMUST00000038406.6
Akr1b8
aldo-keto reductase family 1, member B8
chr3_+_55782500 2.926 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr14_+_75455957 2.819 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr13_+_83504032 2.565 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c

myocyte enhancer factor 2C

chr3_+_102010138 2.553 ENSMUST00000066187.4
Nhlh2
nescient helix loop helix 2
chr18_+_50030977 2.526 ENSMUST00000145726.1
ENSMUST00000128377.1
Tnfaip8

tumor necrosis factor, alpha-induced protein 8

chr13_-_114458720 2.515 ENSMUST00000022287.5
Fst
follistatin
chr3_+_134236483 2.474 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4

CXXC finger 4

chr2_-_166155272 2.466 ENSMUST00000088086.3
Sulf2
sulfatase 2
chr2_-_166155624 2.430 ENSMUST00000109249.2
Sulf2
sulfatase 2
chr1_+_110099295 2.410 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr8_-_109251698 2.355 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr12_+_38781093 2.286 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr3_-_110143937 2.235 ENSMUST00000051253.3
Ntng1
netrin G1
chr12_+_58211772 2.199 ENSMUST00000110671.2
ENSMUST00000044299.2
Sstr1

somatostatin receptor 1

chr6_+_15196949 2.143 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
Foxp2



forkhead box P2



chr4_-_36056726 2.064 ENSMUST00000108124.3
Lingo2
leucine rich repeat and Ig domain containing 2
chr3_-_86548268 2.053 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr14_+_59625281 2.006 ENSMUST00000053949.5
Shisa2
shisa homolog 2 (Xenopus laevis)
chr1_-_183147461 2.004 ENSMUST00000171366.1
Disp1
dispatched homolog 1 (Drosophila)
chr3_+_125404072 1.989 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr4_-_36136463 1.969 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr3_+_55461758 1.957 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr1_+_66321708 1.752 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr1_-_78968079 1.677 ENSMUST00000049117.5
Gm5830
predicted pseudogene 5830
chr3_+_67892189 1.676 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr19_+_8740712 1.642 ENSMUST00000163172.1
1700092M07Rik
RIKEN cDNA 1700092M07 gene
chr1_+_187997821 1.512 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr1_+_187997835 1.490 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr9_-_96437434 1.474 ENSMUST00000070500.2
BC043934
cDNA sequence BC043934
chr18_+_4920509 1.447 ENSMUST00000126977.1
Svil
supervillin
chr9_+_34486125 1.434 ENSMUST00000115148.2
ENSMUST00000183580.1
Kirrel3
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
RP24-225I21.1
chr3_+_125404292 1.420 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr5_-_5266038 1.410 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
Cdk14


cyclin-dependent kinase 14


chr9_+_106368594 1.322 ENSMUST00000172306.2
Dusp7
dual specificity phosphatase 7
chr13_-_78196373 1.315 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr18_-_84086379 1.302 ENSMUST00000060303.8
Tshz1
teashirt zinc finger family member 1
chr2_+_152847993 1.295 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr2_-_114013619 1.292 ENSMUST00000090275.4
Gjd2
gap junction protein, delta 2
chr1_-_193370225 1.281 ENSMUST00000169907.1
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr18_+_4993795 1.257 ENSMUST00000153016.1
Svil
supervillin
chr1_-_193370260 1.229 ENSMUST00000016323.4
Camk1g
calcium/calmodulin-dependent protein kinase I gamma
chr4_-_129261394 1.198 ENSMUST00000145261.1
C77080
expressed sequence C77080
chr14_+_73237891 1.183 ENSMUST00000044405.6
Lpar6
lysophosphatidic acid receptor 6
chr3_-_36571952 1.131 ENSMUST00000029270.3
Ccna2
cyclin A2
chr1_-_37496095 1.123 ENSMUST00000148047.1
ENSMUST00000143636.1
Mgat4a

mannoside acetylglucosaminyltransferase 4, isoenzyme A

chr6_-_99044414 1.108 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr1_+_19212054 1.098 ENSMUST00000064976.4
Tfap2b
transcription factor AP-2 beta
chrX_-_48208566 1.085 ENSMUST00000037960.4
Zdhhc9
zinc finger, DHHC domain containing 9
chr16_-_16829276 1.064 ENSMUST00000023468.5
Spag6
sperm associated antigen 6
chr17_-_48432723 1.023 ENSMUST00000046549.3
Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr8_+_45627709 1.014 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2

sorbin and SH3 domain containing 2

chr3_+_159839729 0.992 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr9_-_16378231 0.979 ENSMUST00000082170.5
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chrX_-_48208870 0.968 ENSMUST00000088935.3
Zdhhc9
zinc finger, DHHC domain containing 9
chr8_+_127064022 0.956 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr8_+_45628176 0.955 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr5_+_92897981 0.944 ENSMUST00000113051.2
Shroom3
shroom family member 3
chr1_+_66322102 0.909 ENSMUST00000123647.1
Map2
microtubule-associated protein 2
chr10_+_94576254 0.903 ENSMUST00000117929.1
Tmcc3
transmembrane and coiled coil domains 3
chr6_+_54039558 0.896 ENSMUST00000046856.7
Chn2
chimerin (chimaerin) 2
chr2_-_72986716 0.856 ENSMUST00000112062.1
Gm11084
predicted gene 11084
chr6_-_99266494 0.854 ENSMUST00000113326.2
Foxp1
forkhead box P1
chr4_-_45532470 0.844 ENSMUST00000147448.1
Shb
src homology 2 domain-containing transforming protein B
chrX_-_23285532 0.834 ENSMUST00000115319.2
Klhl13
kelch-like 13
chr14_-_12345847 0.827 ENSMUST00000022262.4
Fezf2
Fez family zinc finger 2
chr14_-_48667508 0.826 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr2_+_181767040 0.817 ENSMUST00000108756.1
Myt1
myelin transcription factor 1
chr2_+_125859134 0.811 ENSMUST00000028636.6
ENSMUST00000125084.1
Galk2

galactokinase 2

chr1_-_126830632 0.808 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5

NCK-associated protein 5

chr15_-_13173607 0.806 ENSMUST00000036439.4
Cdh6
cadherin 6
chr19_-_14598031 0.789 ENSMUST00000167776.2
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr2_-_18048784 0.779 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr2_+_181767283 0.776 ENSMUST00000108757.2
Myt1
myelin transcription factor 1
chr19_+_23723279 0.775 ENSMUST00000067077.1
Gm9938
predicted gene 9938
chr3_+_40800778 0.770 ENSMUST00000169566.1
Plk4
polo-like kinase 4
chr19_+_24875679 0.769 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr2_+_3114220 0.765 ENSMUST00000072955.5
Fam171a1
family with sequence similarity 171, member A1
chr3_-_88410295 0.750 ENSMUST00000056370.7
Pmf1
polyamine-modulated factor 1
chr19_-_14597983 0.740 ENSMUST00000052011.7
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr1_+_72284367 0.732 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr10_+_94575257 0.702 ENSMUST00000121471.1
Tmcc3
transmembrane and coiled coil domains 3
chr8_+_45627946 0.695 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr18_-_75697639 0.693 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr5_+_8893677 0.686 ENSMUST00000003717.8
Abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr6_-_138426735 0.681 ENSMUST00000162932.1
Lmo3
LIM domain only 3
chr11_+_6560183 0.672 ENSMUST00000109722.2
Ccm2
cerebral cavernous malformation 2
chr3_+_102734496 0.661 ENSMUST00000029451.5
Tspan2
tetraspanin 2
chr2_-_18048347 0.650 ENSMUST00000066885.5
Skida1
SKI/DACH domain containing 1
chr10_+_102158858 0.645 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
Mgat4c


mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)


chr2_-_174346712 0.635 ENSMUST00000168292.1
Gm20721
predicted gene, 20721
chr7_+_101896340 0.634 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr13_-_117025505 0.633 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr15_+_92051153 0.619 ENSMUST00000169825.1
Cntn1
contactin 1
chr1_-_126830786 0.618 ENSMUST00000162646.1
Nckap5
NCK-associated protein 5
chrX_-_93832106 0.614 ENSMUST00000045748.6
Pdk3
pyruvate dehydrogenase kinase, isoenzyme 3
chr3_-_154330543 0.611 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8

LIM homeobox protein 8

chr10_+_24149291 0.603 ENSMUST00000020174.5
Stx7
syntaxin 7
chr8_+_23669653 0.603 ENSMUST00000042352.4
Zmat4
zinc finger, matrin type 4
chr5_-_25100624 0.599 ENSMUST00000030784.7
Prkag2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chrX_+_37126777 0.595 ENSMUST00000016553.4
Nkap
NFKB activating protein
chr8_-_8639363 0.570 ENSMUST00000152698.1
Efnb2
ephrin B2
chr11_+_29718563 0.547 ENSMUST00000060992.5
Rtn4
reticulon 4
chr13_+_93308006 0.533 ENSMUST00000079086.6
Homer1
homer homolog 1 (Drosophila)
chr15_-_98934522 0.528 ENSMUST00000077577.7
Tuba1b
tubulin, alpha 1B
chr12_+_52699297 0.524 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr1_-_175688353 0.518 ENSMUST00000104984.1
Chml
choroideremia-like
chr1_-_172027251 0.513 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr18_+_88971790 0.513 ENSMUST00000023828.7
Rttn
rotatin
chr10_-_95673451 0.513 ENSMUST00000099328.1
Anapc15-ps
anaphase prompoting complex C subunit 15, pseudogene
chr3_+_118430299 0.503 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr19_-_53589067 0.483 ENSMUST00000095978.3
Nutf2-ps1
nuclear transport factor 2, pseudogene 1
chr11_+_120232921 0.481 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1

BAH domain and coiled-coil containing 1

chrX_-_136741155 0.479 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
Morf4l2




mortality factor 4 like 2




chr2_+_83644435 0.463 ENSMUST00000081591.6
Zc3h15
zinc finger CCCH-type containing 15
chr4_+_85205120 0.457 ENSMUST00000107188.3
Sh3gl2
SH3-domain GRB2-like 2
chr1_+_151571373 0.454 ENSMUST00000148810.1
Fam129a
family with sequence similarity 129, member A
chr15_-_100424092 0.449 ENSMUST00000154676.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr4_-_110292719 0.446 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_-_98566762 0.439 ENSMUST00000086912.4
1700010H22Rik
RIKEN cDNA 1700010H22 gene
chr9_+_54980880 0.421 ENSMUST00000093844.3
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr7_+_101896817 0.413 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr4_-_138725262 0.412 ENSMUST00000105811.2
Ubxn10
UBX domain protein 10
chr3_-_126998408 0.409 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chrX_-_95658392 0.408 ENSMUST00000120620.1
Zc4h2
zinc finger, C4H2 domain containing
chr8_-_48555846 0.407 ENSMUST00000110345.1
ENSMUST00000110343.1
Tenm3

teneurin transmembrane protein 3

chr2_-_64975762 0.385 ENSMUST00000156765.1
Grb14
growth factor receptor bound protein 14
chr18_-_56975333 0.379 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr4_-_110286581 0.378 ENSMUST00000138972.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr15_-_93336800 0.378 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr12_+_100110148 0.372 ENSMUST00000021595.8
Psmc1
protease (prosome, macropain) 26S subunit, ATPase 1
chr10_+_56377300 0.365 ENSMUST00000068581.7
Gja1
gap junction protein, alpha 1
chr12_-_36042476 0.360 ENSMUST00000020896.8
Tspan13
tetraspanin 13
chr14_+_4198185 0.359 ENSMUST00000180184.1
Gm2974
predicted gene 2974
chr16_-_63864114 0.357 ENSMUST00000064405.6
Epha3
Eph receptor A3
chr19_-_59170978 0.354 ENSMUST00000172821.2
Vax1
ventral anterior homeobox containing gene 1
chr4_-_59783800 0.352 ENSMUST00000107526.1
ENSMUST00000095063.4
Inip

INTS3 and NABP interacting protein

chr14_-_62454793 0.348 ENSMUST00000128573.1
Gucy1b2
guanylate cyclase 1, soluble, beta 2
chr18_-_43477764 0.345 ENSMUST00000057110.9
Eif3j2
eukaryotic translation initiation factor 3, subunit J2
chr15_-_100424208 0.342 ENSMUST00000154331.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_-_116038734 0.335 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr11_-_93965957 0.329 ENSMUST00000021220.3
Nme1
NME/NM23 nucleoside diphosphate kinase 1
chr15_+_92597104 0.327 ENSMUST00000035399.8
Pdzrn4
PDZ domain containing RING finger 4
chrX_-_95658379 0.326 ENSMUST00000119640.1
Zc4h2
zinc finger, C4H2 domain containing
chr16_+_10812915 0.322 ENSMUST00000115822.1
Gm11172
predicted gene 11172
chr1_+_137928100 0.322 ENSMUST00000054333.2
A130050O07Rik
RIKEN cDNA A130050O07 gene
chr10_+_69925954 0.314 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr4_-_110290884 0.312 ENSMUST00000142722.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_-_31911903 0.309 ENSMUST00000054984.6
Sft2d3
SFT2 domain containing 3
chr14_-_69707493 0.308 ENSMUST00000121142.1
R3hcc1
R3H domain and coiled-coil containing 1
chr18_-_31447383 0.307 ENSMUST00000025110.3
Syt4
synaptotagmin IV
chr8_+_85432686 0.305 ENSMUST00000180883.1
1700051O22Rik
RIKEN cDNA 1700051O22 Gene
chr13_-_36734450 0.304 ENSMUST00000037623.8
Nrn1
neuritin 1
chr2_-_65529275 0.303 ENSMUST00000126837.1
Scn3a
sodium channel, voltage-gated, type III, alpha
chr17_+_27839974 0.302 ENSMUST00000071006.7
Snrpc
U1 small nuclear ribonucleoprotein C
chr10_+_75037066 0.300 ENSMUST00000147802.1
ENSMUST00000020391.5
Rab36

RAB36, member RAS oncogene family

chr12_-_57546121 0.294 ENSMUST00000044380.6
Foxa1
forkhead box A1
chr1_-_172027269 0.290 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr7_-_114117761 0.288 ENSMUST00000069449.5
Rras2
related RAS viral (r-ras) oncogene homolog 2
chr3_-_87885558 0.282 ENSMUST00000005015.8
Prcc
papillary renal cell carcinoma (translocation-associated)
chr4_+_127172866 0.275 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr14_-_69707546 0.273 ENSMUST00000118374.1
R3hcc1
R3H domain and coiled-coil containing 1
chr1_+_66700831 0.269 ENSMUST00000027157.3
ENSMUST00000113995.1
Rpe

ribulose-5-phosphate-3-epimerase

chr11_+_24078173 0.266 ENSMUST00000109514.1
Bcl11a
B cell CLL/lymphoma 11A (zinc finger protein)
chr3_+_32515295 0.264 ENSMUST00000029203.7
Zfp639
zinc finger protein 639
chr5_-_122614445 0.263 ENSMUST00000127220.1
ENSMUST00000031426.7
Ift81

intraflagellar transport 81

chrX_-_95658416 0.262 ENSMUST00000044382.6
Zc4h2
zinc finger, C4H2 domain containing
chrX_-_143933204 0.262 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr6_+_83165920 0.261 ENSMUST00000077407.5
ENSMUST00000113913.1
ENSMUST00000130212.1
Dctn1


dynactin 1


chr2_-_32424005 0.251 ENSMUST00000113307.2
Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr6_-_148946146 0.251 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr9_+_14500611 0.250 ENSMUST00000004200.8
Cwc15
CWC15 homolog (S. cerevisiae)
chr2_-_67194695 0.247 ENSMUST00000147939.1
Gm13598
predicted gene 13598
chr1_-_84839304 0.244 ENSMUST00000027421.6
Trip12
thyroid hormone receptor interactor 12
chr19_-_46969474 0.244 ENSMUST00000086961.7
Nt5c2
5'-nucleotidase, cytosolic II
chr7_+_123123870 0.237 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr16_-_5013505 0.236 ENSMUST00000023191.10
ENSMUST00000090453.5
Rogdi

rogdi homolog (Drosophila)

chr5_+_123907175 0.235 ENSMUST00000023869.8
Denr
density-regulated protein
chrX_+_101429555 0.226 ENSMUST00000033673.6
Nono
non-POU-domain-containing, octamer binding protein
chr2_+_80617045 0.224 ENSMUST00000028384.4
Dusp19
dual specificity phosphatase 19
chr13_-_53473074 0.223 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr7_+_92819892 0.220 ENSMUST00000107180.1
ENSMUST00000107179.1
Rab30

RAB30, member RAS oncogene family

chr7_-_116198487 0.219 ENSMUST00000181981.1
Plekha7
pleckstrin homology domain containing, family A member 7
chr9_+_78051938 0.215 ENSMUST00000024104.7
Gcm1
glial cells missing homolog 1 (Drosophila)
chr10_-_80421847 0.213 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr3_+_51415986 0.206 ENSMUST00000029303.7
Naa15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr5_-_72168142 0.205 ENSMUST00000013693.6
Commd8
COMM domain containing 8
chr2_-_147186389 0.204 ENSMUST00000109970.3
ENSMUST00000067075.5
Nkx2-2

NK2 homeobox 2

chrX_-_143933089 0.199 ENSMUST00000087313.3
Dcx
doublecortin
chr4_-_131937165 0.199 ENSMUST00000155990.1
Epb4.1
erythrocyte protein band 4.1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 9.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.2 4.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.1 36.3 GO:0007638 mechanosensory behavior(GO:0007638)
1.0 3.1 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
0.9 2.6 GO:2001016 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374) positive regulation of macrophage apoptotic process(GO:2000111) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.6 3.6 GO:0060539 diaphragm development(GO:0060539)
0.6 2.8 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.4 1.3 GO:0060023 soft palate development(GO:0060023)
0.4 2.7 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.4 1.1 GO:0097274 urea homeostasis(GO:0097274)
0.3 1.2 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.3 1.4 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 2.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 1.9 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 0.7 GO:0045472 response to ether(GO:0045472)
0.2 2.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 0.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.8 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 1.0 GO:0003383 apical constriction(GO:0003383)
0.2 0.8 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.2 0.8 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.2 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 0.6 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 0.6 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.8 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 0.4 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 2.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144)
0.1 2.6 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 2.1 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 2.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 1.3 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 1.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.2 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.8 GO:0006012 galactose metabolic process(GO:0006012)
0.1 1.0 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.5 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.1 1.0 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 1.2 GO:0080111 DNA demethylation(GO:0080111)
0.1 0.6 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 1.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.3 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.7 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.1 1.9 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 0.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.2 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 2.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 2.2 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.4 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 3.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.0 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.8 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) stress-induced premature senescence(GO:0090400)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 1.9 GO:0021954 central nervous system neuron development(GO:0021954)
0.0 0.1 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 1.2 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.9 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.0 0.2 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561) regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.7 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.1 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0 1.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.8 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.3 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.2 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.2 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.0 0.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0010715 regulation of extracellular matrix disassembly(GO:0010715) smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.4 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 1.7 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 1.1 GO:0000086 G2/M transition of mitotic cell cycle(GO:0000086)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 2.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 1.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.2 2.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 0.8 GO:0060187 cell pole(GO:0060187)
0.2 1.3 GO:0005818 aster(GO:0005818)
0.2 1.1 GO:0001940 male pronucleus(GO:0001940)
0.2 0.8 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 0.6 GO:0070820 tertiary granule(GO:0070820)
0.1 1.0 GO:0033269 internode region of axon(GO:0033269)
0.1 1.7 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 3.6 GO:0043034 costamere(GO:0043034)
0.1 0.8 GO:0098536 deuterosome(GO:0098536)
0.1 0.6 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 1.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 2.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.9 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.7 2.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.5 3.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.5 3.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.4 1.8 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 2.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 0.8 GO:0004335 galactokinase activity(GO:0004335)
0.3 1.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 2.6 GO:0003680 AT DNA binding(GO:0003680)
0.2 2.5 GO:0048185 activin binding(GO:0048185)
0.2 0.2 GO:0008579 protein tyrosine/threonine phosphatase activity(GO:0008330) JUN kinase phosphatase activity(GO:0008579)
0.2 0.7 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.2 0.8 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 3.0 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 2.0 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.2 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 42.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.1 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 0.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.1 0.4 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 3.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 0.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 2.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.5 GO:0043495 protein anchor(GO:0043495)
0.1 0.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 2.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.2 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 1.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.5 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.0 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 1.4 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.7 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 3.2 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 3.2 GO:0051015 actin filament binding(GO:0051015)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960) neuregulin binding(GO:0038132)
0.0 0.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 2.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)