Motif ID: Atf1_Creb5

Z-value: 0.530

Transcription factors associated with Atf1_Creb5:

Gene SymbolEntrez IDGene Name
Atf1 ENSMUSG00000023027.6 Atf1
Creb5 ENSMUSG00000053007.6 Creb5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Atf1mm10_v2_chr15_+_100227819_1002278560.565.7e-03Click!
Creb5mm10_v2_chr6_+_53573364_535733940.203.7e-01Click!


Activity profile for motif Atf1_Creb5.

activity profile for motif Atf1_Creb5


Sorted Z-values histogram for motif Atf1_Creb5

Sorted Z-values for motif Atf1_Creb5



Network of associatons between targets according to the STRING database.



First level regulatory network of Atf1_Creb5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_112679314 1.349 ENSMUST00000084705.5
ENSMUST00000059768.10
 Tead1

TEA domain family member 1

chr3_+_127553462 0.916 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr10_-_17947997 0.875 ENSMUST00000037879.6
 Heca
headcase homolog (Drosophila)
chr9_-_96752822 0.799 ENSMUST00000152594.1
 Zbtb38
zinc finger and BTB domain containing 38
chr3_+_145118564 0.741 ENSMUST00000098538.2
ENSMUST00000106192.2
ENSMUST00000029920.8
ENSMUST00000098539.2
 Odf2l



outer dense fiber of sperm tails 2-like



chr2_+_120609383 0.737 ENSMUST00000124187.1
 Haus2
HAUS augmin-like complex, subunit 2
chr7_+_30413744 0.731 ENSMUST00000032800.9
 Tyrobp
TYRO protein tyrosine kinase binding protein
chr7_+_44496588 0.723 ENSMUST00000107927.3
 Fam71e1
family with sequence similarity 71, member E1
chr7_+_112679327 0.695 ENSMUST00000106638.2
 Tead1
TEA domain family member 1
chr3_-_127553233 0.677 ENSMUST00000029588.5
 Larp7
La ribonucleoprotein domain family, member 7
chr4_+_11704439 0.665 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chrX_-_21061981 0.657 ENSMUST00000040628.5
ENSMUST00000115333.2
ENSMUST00000115334.1
 Zfp182


zinc finger protein 182


chr2_+_109280738 0.645 ENSMUST00000028527.7
 Kif18a
kinesin family member 18A
chrX_+_170009659 0.643 ENSMUST00000179760.1
 Gm21887
predicted gene, 21887
chr2_+_105668888 0.626 ENSMUST00000111086.4
ENSMUST00000111087.3
 Pax6

paired box gene 6

chr7_+_90442729 0.625 ENSMUST00000061767.4
ENSMUST00000107206.1
 Crebzf

CREB/ATF bZIP transcription factor

chr6_-_129533267 0.609 ENSMUST00000181594.1
 1700101I11Rik
RIKEN cDNA 1700101I11 gene
chr6_+_83034173 0.583 ENSMUST00000000707.2
ENSMUST00000101257.3
 Loxl3

lysyl oxidase-like 3

chr4_-_107810948 0.580 ENSMUST00000097930.1
 B230314M03Rik
RIKEN cDNA B230314M03 gene
chr7_+_130865835 0.578 ENSMUST00000075181.4
ENSMUST00000048180.5
 Plekha1

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.0 GO:0014883 transition between fast and slow fiber(GO:0014883) positive regulation of stem cell population maintenance(GO:1902459)
0.2 0.9 GO:0021905 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918)
0.1 0.9 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.8 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.8 GO:0009409 response to cold(GO:0009409)
0.1 0.7 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.7 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.6 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.6 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.6 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 0.5 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.2 0.5 GO:1900736 regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.5 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.5 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 0.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 0.5 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 0.5 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:0005828 kinetochore microtubule(GO:0005828)
0.1 0.6 GO:0098536 deuterosome(GO:0098536)
0.0 0.6 GO:0051233 spindle midzone(GO:0051233)
0.0 0.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.5 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0000242 pericentriolar material(GO:0000242)
0.1 0.4 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.1 0.4 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 1.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.6 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.2 0.6 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.3 GO:0004994 somatostatin receptor activity(GO:0004994)