Motif ID: Nr5a2

Z-value: 0.896


Transcription factors associated with Nr5a2:

Gene SymbolEntrez IDGene Name
Nr5a2 ENSMUSG00000026398.8 Nr5a2



Activity profile for motif Nr5a2.

activity profile for motif Nr5a2


Sorted Z-values histogram for motif Nr5a2

Sorted Z-values for motif Nr5a2



Network of associatons between targets according to the STRING database.



First level regulatory network of Nr5a2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_-_79804717 1.763 ENSMUST00000023057.8
 Nptxr
neuronal pentraxin receptor
chr13_-_56296551 1.724 ENSMUST00000021970.9
 Cxcl14
chemokine (C-X-C motif) ligand 14
chr13_+_21722057 1.653 ENSMUST00000110476.3
 Hist1h2bm
histone cluster 1, H2bm
chr7_+_100493795 1.553 ENSMUST00000129324.1
 Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_+_100494044 1.497 ENSMUST00000153287.1
 Ucp2
uncoupling protein 2 (mitochondrial, proton carrier)
chr7_-_4522427 1.117 ENSMUST00000098859.3
 Tnni3
troponin I, cardiac 3
chr9_-_77347816 1.091 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
 Mlip



muscular LMNA-interacting protein



chr11_-_4704334 0.986 ENSMUST00000058407.5
 Uqcr10
ubiquinol-cytochrome c reductase, complex III subunit X
chr14_+_75455957 0.982 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr13_-_21787218 0.981 ENSMUST00000091751.2
 Hist1h2an
histone cluster 1, H2an
chr8_+_124793061 0.956 ENSMUST00000041106.7
 Trim67
tripartite motif-containing 67
chr11_-_3504766 0.953 ENSMUST00000044507.5
 Inpp5j
inositol polyphosphate 5-phosphatase J
chr3_+_14886426 0.953 ENSMUST00000029078.7
 Car2
carbonic anhydrase 2
chrX_-_72656135 0.949 ENSMUST00000055966.6
 Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr2_-_166155624 0.939 ENSMUST00000109249.2
 Sulf2
sulfatase 2
chr2_+_121357714 0.937 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
 Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr8_+_124793013 0.922 ENSMUST00000167588.1
 Trim67
tripartite motif-containing 67
chr11_+_67586520 0.898 ENSMUST00000108682.2
 Gas7
growth arrest specific 7
chr15_+_85510812 0.894 ENSMUST00000079690.2
 Gm4825
predicted pseudogene 4825
chr1_+_131970589 0.885 ENSMUST00000027695.6
 Slc45a3
solute carrier family 45, member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 128 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.9 GO:0006334 nucleosome assembly(GO:0006334)
0.0 3.1 GO:0006342 chromatin silencing(GO:0006342)
0.2 2.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 2.6 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 2.4 GO:0009060 aerobic respiration(GO:0009060)
0.1 1.9 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.6 1.7 GO:2000501 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.1 1.7 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.7 GO:0051017 actin filament bundle assembly(GO:0051017)
0.3 1.6 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.3 GO:0014003 oligodendrocyte development(GO:0014003)
0.2 1.1 GO:0006113 fermentation(GO:0006113)
0.0 1.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.3 1.0 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.3 1.0 GO:0035672 regulation of cellular pH reduction(GO:0032847) oligopeptide transmembrane transport(GO:0035672)
0.2 1.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 1.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.3 0.9 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 4.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 3.6 GO:0043209 myelin sheath(GO:0043209)
0.1 3.2 GO:0045259 proton-transporting ATP synthase complex(GO:0045259)
0.0 3.0 GO:0016605 PML body(GO:0016605)
0.1 1.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.6 GO:0070469 respiratory chain(GO:0070469)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.2 1.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.2 1.0 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 88 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 2.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.8 GO:0005518 collagen binding(GO:0005518)
0.6 2.6 GO:0004111 creatine kinase activity(GO:0004111)
0.6 1.8 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 1.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 1.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 1.5 GO:0008009 chemokine activity(GO:0008009)
0.1 1.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 1.1 GO:0020037 heme binding(GO:0020037)
0.3 1.0 GO:0030172 troponin C binding(GO:0030172)
0.3 1.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.3 1.0 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 1.0 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.0 GO:0015266 protein channel activity(GO:0015266)
0.3 0.9 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)