Motif ID: Nkx2-6

Z-value: 0.191


Transcription factors associated with Nkx2-6:

Gene SymbolEntrez IDGene Name
Nkx2-6 ENSMUSG00000044186.9 Nkx2-6



Activity profile for motif Nkx2-6.

activity profile for motif Nkx2-6


Sorted Z-values histogram for motif Nkx2-6

Sorted Z-values for motif Nkx2-6



Network of associatons between targets according to the STRING database.



First level regulatory network of Nkx2-6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_116031047 0.365 ENSMUST00000106612.1
 Sox6
SRY-box containing gene 6
chr4_-_91399984 0.305 ENSMUST00000102799.3
 Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_+_62619515 0.255 ENSMUST00000084521.4
ENSMUST00000107424.1
 Rgs3

regulator of G-protein signaling 3

chr9_-_10904766 0.172 ENSMUST00000160216.1
 Cntn5
contactin 5
chr9_-_10904697 0.149 ENSMUST00000162484.1
 Cntn5
contactin 5
chr15_-_78773452 0.125 ENSMUST00000018313.5
 Mfng
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_179960472 0.113 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr6_+_70726430 0.111 ENSMUST00000103410.1
 Igkc
immunoglobulin kappa constant
chr2_+_23069210 0.111 ENSMUST00000155602.1
 Acbd5
acyl-Coenzyme A binding domain containing 5
chr1_+_156035392 0.106 ENSMUST00000111757.3
 Tor1aip2
torsin A interacting protein 2
chr1_+_179961110 0.092 ENSMUST00000076687.5
ENSMUST00000097450.3
 Cdc42bpa

CDC42 binding protein kinase alpha

chr3_+_87525572 0.089 ENSMUST00000170036.1
ENSMUST00000117293.1
 Etv3

ets variant gene 3

chr7_-_116237767 0.085 ENSMUST00000182834.1
 Plekha7
pleckstrin homology domain containing, family A member 7
chr1_-_156034826 0.080 ENSMUST00000141878.1
ENSMUST00000123705.1
 Tor1aip1

torsin A interacting protein 1

chr1_-_156034800 0.058 ENSMUST00000169241.1
 Tor1aip1
torsin A interacting protein 1
chr19_+_8819401 0.046 ENSMUST00000096753.3
 Hnrnpul2
heterogeneous nuclear ribonucleoprotein U-like 2
chr11_+_103774150 0.042 ENSMUST00000000127.5
 Wnt3
wingless-related MMTV integration site 3
chr2_+_3114220 0.031 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr12_-_108702265 0.009 ENSMUST00000167978.1
ENSMUST00000021691.4
 Degs2

degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase

chr2_-_147186389 0.007 ENSMUST00000109970.3
ENSMUST00000067075.5
 Nkx2-2

NK2 homeobox 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)