Motif ID: Fosb

Z-value: 0.416


Transcription factors associated with Fosb:

Gene SymbolEntrez IDGene Name
Fosb ENSMUSG00000003545.2 Fosb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosbmm10_v2_chr7_-_19310035_19310050-0.116.1e-01Click!


Activity profile for motif Fosb.

activity profile for motif Fosb


Sorted Z-values histogram for motif Fosb

Sorted Z-values for motif Fosb



Network of associatons between targets according to the STRING database.



First level regulatory network of Fosb

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_78930940 1.590 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr6_+_17463927 1.052 ENSMUST00000115442.1
 Met
met proto-oncogene
chr8_-_8639363 0.723 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr17_-_35697971 0.581 ENSMUST00000146472.1
 Ddr1
discoidin domain receptor family, member 1
chr8_+_107293500 0.560 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
 Nfat5


nuclear factor of activated T cells 5


chr17_+_35841668 0.547 ENSMUST00000174124.1
 Mdc1
mediator of DNA damage checkpoint 1
chr11_-_120630516 0.524 ENSMUST00000106181.1
 Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr6_-_113934679 0.510 ENSMUST00000101044.2
 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr14_+_80000292 0.508 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr15_-_102257306 0.468 ENSMUST00000135466.1
 Rarg
retinoic acid receptor, gamma
chr11_-_84067063 0.462 ENSMUST00000108101.1
 Dusp14
dual specificity phosphatase 14
chr7_+_139834148 0.430 ENSMUST00000026548.7
 Gpr123
G protein-coupled receptor 123
chr7_-_133782721 0.426 ENSMUST00000063669.1
 Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr9_+_44240668 0.419 ENSMUST00000092426.3
 Ccdc153
coiled-coil domain containing 153
chr4_-_43558386 0.349 ENSMUST00000130353.1
 Tln1
talin 1
chr7_-_80401707 0.340 ENSMUST00000120753.1
 Furin
furin (paired basic amino acid cleaving enzyme)
chr9_+_96259246 0.336 ENSMUST00000179065.1
ENSMUST00000165768.2
 Tfdp2

transcription factor Dp 2

chr2_-_18048784 0.333 ENSMUST00000142856.1
 Skida1
SKI/DACH domain containing 1
chr2_-_29253001 0.330 ENSMUST00000071201.4
 Ntng2
netrin G2
chr12_-_84194007 0.320 ENSMUST00000110294.1
 Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr2_-_45110241 0.307 ENSMUST00000177302.1
 Zeb2
zinc finger E-box binding homeobox 2
chr1_+_134560190 0.305 ENSMUST00000112198.1
ENSMUST00000112197.1
 Kdm5b

lysine (K)-specific demethylase 5B

chr5_-_86676346 0.304 ENSMUST00000038448.6
 Tmprss11bnl
transmembrane protease, serine 11b N terminal like
chr18_+_40258361 0.301 ENSMUST00000091927.4
 Kctd16
potassium channel tetramerisation domain containing 16
chr9_+_96258697 0.297 ENSMUST00000179416.1
 Tfdp2
transcription factor Dp 2
chr10_-_64090241 0.263 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chrX_+_73675500 0.256 ENSMUST00000171398.1
 Slc6a8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr1_+_165769392 0.248 ENSMUST00000040298.4
 Creg1
cellular repressor of E1A-stimulated genes 1
chr15_-_102257449 0.240 ENSMUST00000043172.8
 Rarg
retinoic acid receptor, gamma
chr7_-_4778141 0.230 ENSMUST00000094892.5
 Il11
interleukin 11
chr17_+_78508063 0.230 ENSMUST00000024880.9
 Vit
vitrin
chr9_+_122888471 0.227 ENSMUST00000063980.6
 Zkscan7
zinc finger with KRAB and SCAN domains 7
chr18_+_82910863 0.226 ENSMUST00000171238.1
 Zfp516
zinc finger protein 516
chr19_+_5447692 0.222 ENSMUST00000025850.5
 Fosl1
fos-like antigen 1
chr14_+_79426454 0.207 ENSMUST00000061222.7
 Kbtbd7
kelch repeat and BTB (POZ) domain containing 7
chr14_-_55758458 0.189 ENSMUST00000001497.7
 Cideb
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr6_+_86849488 0.188 ENSMUST00000089519.6
ENSMUST00000113668.1
 Aak1

AP2 associated kinase 1

chr11_-_70015346 0.187 ENSMUST00000018718.7
ENSMUST00000102574.3
 Acadvl

acyl-Coenzyme A dehydrogenase, very long chain

chr9_-_119977250 0.185 ENSMUST00000035101.7
 Csrnp1
cysteine-serine-rich nuclear protein 1
chr13_+_15463837 0.182 ENSMUST00000110510.3
 Gli3
GLI-Kruppel family member GLI3
chr3_+_116878227 0.168 ENSMUST00000040260.6
 Frrs1
ferric-chelate reductase 1
chr8_+_4226827 0.161 ENSMUST00000053035.6
 Lrrc8e
leucine rich repeat containing 8 family, member E
chr17_+_35049966 0.156 ENSMUST00000007257.9
 Clic1
chloride intracellular channel 1
chr5_-_62766153 0.155 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_-_76014318 0.150 ENSMUST00000060807.5
 Fam83h
family with sequence similarity 83, member H
chr11_-_50210765 0.130 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
 Sqstm1


sequestosome 1


chr12_+_71015966 0.129 ENSMUST00000046305.5
 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr7_-_127946725 0.124 ENSMUST00000118755.1
ENSMUST00000094026.3
 Prss36

protease, serine, 36

chr1_+_134560157 0.120 ENSMUST00000047714.7
 Kdm5b
lysine (K)-specific demethylase 5B
chr7_-_105787567 0.118 ENSMUST00000144189.1
 Dchs1
dachsous 1 (Drosophila)
chr11_+_80428598 0.116 ENSMUST00000173938.1
ENSMUST00000017572.7
 Psmd11

proteasome (prosome, macropain) 26S subunit, non-ATPase, 11

chr17_+_35841491 0.114 ENSMUST00000082337.6
 Mdc1
mediator of DNA damage checkpoint 1
chr3_+_123267445 0.110 ENSMUST00000047923.7
 Sec24d
Sec24 related gene family, member D (S. cerevisiae)
chr4_-_140665891 0.103 ENSMUST00000069623.5
 Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr7_-_29505447 0.100 ENSMUST00000183096.1
ENSMUST00000085809.4
 Sipa1l3

signal-induced proliferation-associated 1 like 3

chr10_-_64090265 0.089 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr7_+_126776939 0.084 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr5_-_107875035 0.084 ENSMUST00000138111.1
ENSMUST00000112642.1
 Evi5

ecotropic viral integration site 5

chr1_-_182517447 0.083 ENSMUST00000068505.8
 Capn2
calpain 2
chr8_+_36489191 0.082 ENSMUST00000171777.1
 6430573F11Rik
RIKEN cDNA 6430573F11 gene
chr17_-_45592262 0.078 ENSMUST00000164769.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr15_+_102503722 0.072 ENSMUST00000096145.4
 Gm10337
predicted gene 10337
chr1_+_86064619 0.056 ENSMUST00000027432.8
 Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr2_+_167777467 0.051 ENSMUST00000139927.1
ENSMUST00000127441.1
 Gm14321

predicted gene 14321

chr2_+_152105722 0.035 ENSMUST00000099225.2
 Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr17_-_45592485 0.033 ENSMUST00000166119.1
 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chr10_-_86011833 0.028 ENSMUST00000105304.1
ENSMUST00000061699.5
 Bpifc

BPI fold containing family C

chr11_+_117232254 0.026 ENSMUST00000106354.2
 Sept9
septin 9
chr7_+_127800844 0.019 ENSMUST00000106271.1
ENSMUST00000138432.1
 Hsd3b7

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

chr9_-_109059216 0.018 ENSMUST00000112053.1
 Trex1
three prime repair exonuclease 1
chr14_+_27622433 0.009 ENSMUST00000090302.5
 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr4_-_140774196 0.009 ENSMUST00000026381.6
 Padi4
peptidyl arginine deiminase, type IV

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 1.4 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.1 0.7 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.1 0.2 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.1 0.4 GO:0034720 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) histone H3-K4 demethylation(GO:0034720) mammary duct terminal end bud growth(GO:0060763)
0.1 0.3 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192) cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.4 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.0 0.5 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)