Motif ID: Fosb

Z-value: 0.416


Transcription factors associated with Fosb:

Gene SymbolEntrez IDGene Name
Fosb ENSMUSG00000003545.2 Fosb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosbmm10_v2_chr7_-_19310035_19310050-0.116.1e-01Click!


Activity profile for motif Fosb.

activity profile for motif Fosb


Sorted Z-values histogram for motif Fosb

Sorted Z-values for motif Fosb



Network of associatons between targets according to the STRING database.



First level regulatory network of Fosb

PNG image of the network

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Top targets:


Showing 1 to 20 of 72 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_78930940 1.590 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
Chodl


chondrolectin


chr6_+_17463927 1.052 ENSMUST00000115442.1
Met
met proto-oncogene
chr8_-_8639363 0.723 ENSMUST00000152698.1
Efnb2
ephrin B2
chr17_-_35697971 0.581 ENSMUST00000146472.1
Ddr1
discoidin domain receptor family, member 1
chr8_+_107293500 0.560 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
Nfat5


nuclear factor of activated T cells 5


chr17_+_35841668 0.547 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr11_-_120630516 0.524 ENSMUST00000106181.1
Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr6_-_113934679 0.510 ENSMUST00000101044.2
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr14_+_80000292 0.508 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr15_-_102257306 0.468 ENSMUST00000135466.1
Rarg
retinoic acid receptor, gamma
chr11_-_84067063 0.462 ENSMUST00000108101.1
Dusp14
dual specificity phosphatase 14
chr7_+_139834148 0.430 ENSMUST00000026548.7
Gpr123
G protein-coupled receptor 123
chr7_-_133782721 0.426 ENSMUST00000063669.1
Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr9_+_44240668 0.419 ENSMUST00000092426.3
Ccdc153
coiled-coil domain containing 153
chr4_-_43558386 0.349 ENSMUST00000130353.1
Tln1
talin 1
chr7_-_80401707 0.340 ENSMUST00000120753.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr9_+_96259246 0.336 ENSMUST00000179065.1
ENSMUST00000165768.2
Tfdp2

transcription factor Dp 2

chr2_-_18048784 0.333 ENSMUST00000142856.1
Skida1
SKI/DACH domain containing 1
chr2_-_29253001 0.330 ENSMUST00000071201.4
Ntng2
netrin G2
chr12_-_84194007 0.320 ENSMUST00000110294.1
Elmsan1
ELM2 and Myb/SANT-like domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.2 0.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.7 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.6 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.0 0.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.4 GO:0034720 positive regulation of mammary gland epithelial cell proliferation(GO:0033601) histone H3-K4 demethylation(GO:0034720) mammary duct terminal end bud growth(GO:0060763)
0.0 0.4 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 0.3 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.2 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192) cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.1 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)

Gene overrepresentation in cellular_component category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0042581 specific granule(GO:0042581)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0044754 amphisome(GO:0044753) autolysosome(GO:0044754)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0045095 keratin filament(GO:0045095)

Gene overrepresentation in molecular_function category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 1.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.7 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)