Motif ID: Pbx1_Pbx3
Z-value: 1.250
Transcription factors associated with Pbx1_Pbx3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Pbx1 | ENSMUSG00000052534.9 | Pbx1 |
| Pbx3 | ENSMUSG00000038718.9 | Pbx3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Pbx1 | mm10_v2_chr1_-_168431896_168431905 | 0.32 | 1.4e-01 | Click! |
| Pbx3 | mm10_v2_chr2_-_34372004_34372044 | 0.20 | 3.5e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 128 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 9.0 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.5 | 5.5 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.3 | 4.7 | GO:0042759 | long-chain fatty acid biosynthetic process(GO:0042759) |
| 0.0 | 3.5 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.5 | 2.6 | GO:0042997 | negative regulation of Golgi to plasma membrane protein transport(GO:0042997) |
| 0.4 | 2.5 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.1 | 1.9 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 1.9 | GO:0045638 | negative regulation of myeloid cell differentiation(GO:0045638) |
| 0.4 | 1.8 | GO:0061074 | regulation of neural retina development(GO:0061074) |
| 0.1 | 1.8 | GO:0060736 | positive regulation of glial cell proliferation(GO:0060252) prostate gland growth(GO:0060736) |
| 0.2 | 1.7 | GO:2000809 | neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.1 | 1.7 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 0.1 | 1.6 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.5 | 1.5 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.0 | 1.5 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 1.4 | GO:0014066 | regulation of phosphatidylinositol 3-kinase signaling(GO:0014066) |
| 0.0 | 1.4 | GO:0050714 | positive regulation of protein secretion(GO:0050714) |
| 0.4 | 1.3 | GO:0060023 | soft palate development(GO:0060023) |
| 0.1 | 1.3 | GO:0060346 | bone trabecula formation(GO:0060346) |
| 0.1 | 1.3 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 53 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 9.0 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.3 | 3.1 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 2.6 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 2.3 | GO:0005604 | basement membrane(GO:0005604) |
| 0.2 | 1.9 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.3 | 1.7 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.1 | 1.7 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 1.6 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.4 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 1.4 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.3 | 1.3 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.1 | 1.2 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 1.1 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 1.1 | GO:0005814 | centriole(GO:0005814) |
| 0.2 | 1.0 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 1.0 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 1.0 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.8 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.8 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 81 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 11.0 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.4 | 9.2 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.8 | 5.5 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
| 0.1 | 5.4 | GO:0003823 | antigen binding(GO:0003823) |
| 1.1 | 4.3 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.1 | 4.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 2.7 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.1 | 2.6 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 1.8 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 1.8 | GO:0005496 | steroid binding(GO:0005496) |
| 0.6 | 1.7 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
| 0.3 | 1.7 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.1 | 1.5 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.1 | 1.3 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.0 | 1.2 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.1 | 1.1 | GO:0035184 | histone threonine kinase activity(GO:0035184) |
| 0.1 | 1.1 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 1.1 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 1.0 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 1.0 | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) |
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