Motif ID: Pax4

Z-value: 0.523


Transcription factors associated with Pax4:

Gene SymbolEntrez IDGene Name
Pax4 ENSMUSG00000029706.9 Pax4



Activity profile for motif Pax4.

activity profile for motif Pax4


Sorted Z-values histogram for motif Pax4

Sorted Z-values for motif Pax4



Network of associatons between targets according to the STRING database.



First level regulatory network of Pax4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_58836721 2.228 ENSMUST00000052907.5
Adamts19
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19
chrX_+_73192222 1.418 ENSMUST00000101486.4
Xlr3b
X-linked lymphocyte-regulated 3B
chr9_-_58159201 1.148 ENSMUST00000041477.7
Islr
immunoglobulin superfamily containing leucine-rich repeat
chrX_-_73097017 1.137 ENSMUST00000114524.2
ENSMUST00000074619.5
Xlr3a

X-linked lymphocyte-regulated 3A

chr15_-_88978958 1.118 ENSMUST00000042594.6
ENSMUST00000109368.1
Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

chr13_-_23430826 1.108 ENSMUST00000153753.1
ENSMUST00000141543.1
C230035I16Rik

RIKEN cDNA C230035I16 gene

chr8_-_84773381 1.093 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr4_+_136357423 1.077 ENSMUST00000182167.1
Gm17388
predicted gene, 17388
chr4_-_88033328 1.010 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_+_78499087 0.976 ENSMUST00000017488.4
Vtn
vitronectin
chr12_-_90738438 0.932 ENSMUST00000082432.3
Dio2
deiodinase, iodothyronine, type II
chrM_+_3906 0.758 ENSMUST00000082396.1
mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr4_+_147132038 0.661 ENSMUST00000084149.3
Gm13139
predicted gene 13139
chr9_-_103222063 0.611 ENSMUST00000170904.1
Trf
transferrin
chrX_+_142228177 0.606 ENSMUST00000112914.1
Nxt2
nuclear transport factor 2-like export factor 2
chrX_+_142227923 0.600 ENSMUST00000042329.5
Nxt2
nuclear transport factor 2-like export factor 2
chr12_+_71048338 0.589 ENSMUST00000135709.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr13_-_101768154 0.570 ENSMUST00000055518.6
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chrX_+_9199865 0.555 ENSMUST00000069763.2
Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr10_+_119992916 0.509 ENSMUST00000105261.2
Grip1
glutamate receptor interacting protein 1
chr9_+_32696005 0.484 ENSMUST00000034534.6
ENSMUST00000050797.7
ENSMUST00000184887.1
Ets1


E26 avian leukemia oncogene 1, 5' domain


chr10_-_62792243 0.463 ENSMUST00000020268.5
Ccar1
cell division cycle and apoptosis regulator 1
chr4_-_58987095 0.441 ENSMUST00000030069.6
Ptgr1
prostaglandin reductase 1
chr13_+_75089826 0.437 ENSMUST00000022075.4
Pcsk1
proprotein convertase subtilisin/kexin type 1
chrX_-_8206475 0.427 ENSMUST00000089403.3
ENSMUST00000077595.5
ENSMUST00000089402.3
ENSMUST00000082320.5
Porcn



porcupine homolog (Drosophila)



chr15_-_50889691 0.410 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr4_+_146610961 0.400 ENSMUST00000130825.1
Gm13248
predicted gene 13248
chr12_-_98577940 0.372 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chrM_+_11734 0.360 ENSMUST00000082418.1
mt-Nd5
mitochondrially encoded NADH dehydrogenase 5
chr13_+_38204928 0.353 ENSMUST00000091641.5
ENSMUST00000178564.1
Snrnp48

small nuclear ribonucleoprotein 48 (U11/U12)

chr2_-_33086366 0.349 ENSMUST00000049618.2
Garnl3
GTPase activating RANGAP domain-like 3
chr1_-_88008520 0.312 ENSMUST00000040783.4
Usp40
ubiquitin specific peptidase 40
chr2_-_125506385 0.281 ENSMUST00000028633.6
Fbn1
fibrillin 1
chr2_+_73271925 0.262 ENSMUST00000090813.5
Sp9
trans-acting transcription factor 9
chr5_+_124552845 0.242 ENSMUST00000071057.7
Ddx55
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr7_+_7171330 0.228 ENSMUST00000051435.7
Zfp418
zinc finger protein 418
chr1_-_156034800 0.216 ENSMUST00000169241.1
Tor1aip1
torsin A interacting protein 1
chr2_-_114654943 0.212 ENSMUST00000028640.7
ENSMUST00000102542.3
Dph6

diphthamine biosynthesis 6

chr2_-_114654861 0.205 ENSMUST00000055144.7
Dph6
diphthamine biosynthesis 6
chr5_-_121502980 0.199 ENSMUST00000079368.3
Adam1b
a disintegrin and metallopeptidase domain 1b
chr14_-_59395381 0.186 ENSMUST00000166912.2
Phf11c
PHD finger protein 11C
chr10_+_90071095 0.184 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr14_-_12823031 0.183 ENSMUST00000067491.6
ENSMUST00000177814.1
ENSMUST00000112658.1
ENSMUST00000112657.2
Cadps



Ca2+-dependent secretion activator



chr12_-_80112998 0.158 ENSMUST00000165114.1
ENSMUST00000021552.1
Zfp36l1

zinc finger protein 36, C3H type-like 1

chr2_+_22895482 0.152 ENSMUST00000053729.7
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr3_+_95624971 0.152 ENSMUST00000058230.6
ENSMUST00000037983.4
Ensa

endosulfine alpha

chr18_+_53862087 0.144 ENSMUST00000069597.6
Csnk1g3
casein kinase 1, gamma 3
chr8_-_22476809 0.144 ENSMUST00000163774.1
ENSMUST00000033935.8
Smim19

small integral membrane protein 19

chr12_+_33314277 0.139 ENSMUST00000133549.1
Atxn7l1
ataxin 7-like 1
chr15_-_50890041 0.130 ENSMUST00000077935.5
Trps1
trichorhinophalangeal syndrome I (human)
chr9_-_101198999 0.125 ENSMUST00000066773.7
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr5_-_116288978 0.122 ENSMUST00000050178.6
Ccdc60
coiled-coil domain containing 60
chr2_+_105904629 0.112 ENSMUST00000037499.5
Immp1l
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr18_+_76930017 0.108 ENSMUST00000026487.4
Ier3ip1
immediate early response 3 interacting protein 1
chr15_+_78597047 0.104 ENSMUST00000043069.5
Cyth4
cytohesin 4
chr4_+_150087365 0.101 ENSMUST00000094451.3
Gpr157
G protein-coupled receptor 157
chr6_+_136518820 0.098 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr16_+_15637844 0.098 ENSMUST00000023352.8
Prkdc
protein kinase, DNA activated, catalytic polypeptide
chr2_-_168741752 0.092 ENSMUST00000029060.4
Atp9a
ATPase, class II, type 9A
chr2_-_105904484 0.090 ENSMUST00000122965.1
Elp4
elongation protein 4 homolog (S. cerevisiae)
chr7_-_144738520 0.082 ENSMUST00000118556.2
ENSMUST00000033393.8
Ano1

anoctamin 1, calcium activated chloride channel

chr11_+_43587040 0.072 ENSMUST00000056256.2
4933415A04Rik
RIKEN cDNA 4933415A04 gene
chr2_+_22895583 0.063 ENSMUST00000152170.1
Pdss1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr2_-_168741898 0.047 ENSMUST00000109176.1
ENSMUST00000178504.1
Atp9a

ATPase, class II, type 9A

chr7_-_45366714 0.040 ENSMUST00000107779.1
Ppfia3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr4_+_156235999 0.040 ENSMUST00000179543.1
ENSMUST00000179886.1
Noc2l

nucleolar complex associated 2 homolog (S. cerevisiae)

chr3_+_20057802 0.037 ENSMUST00000002502.5
Hltf
helicase-like transcription factor
chr7_-_144738478 0.031 ENSMUST00000121758.1
Ano1
anoctamin 1, calcium activated chloride channel
chr19_+_53140430 0.026 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr5_-_116591811 0.026 ENSMUST00000076124.5
Srrm4
serine/arginine repetitive matrix 4
chr15_-_79164477 0.022 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr15_+_80977765 0.021 ENSMUST00000139517.1
ENSMUST00000042506.8
ENSMUST00000137255.1
Sgsm3


small G protein signaling modulator 3


chr9_-_57158288 0.018 ENSMUST00000065358.7
Commd4
COMM domain containing 4
chr17_+_35059035 0.018 ENSMUST00000007255.6
ENSMUST00000174493.1
Ddah2

dimethylarginine dimethylaminohydrolase 2

chr12_-_84218835 0.011 ENSMUST00000046266.6
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr19_-_32712287 0.004 ENSMUST00000070210.4
Atad1
ATPase family, AAA domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.2 0.9 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.1 0.5 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.1 1.0 GO:0007379 segment specification(GO:0007379)
0.1 0.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 1.0 GO:0097421 liver regeneration(GO:0097421)
0.1 0.3 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
0.1 1.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.6 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460)
0.1 0.6 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.4 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 2.6 GO:0007286 spermatid development(GO:0007286)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.4 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.6 GO:0097433 dense body(GO:0097433)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.1 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.4 GO:0016631 enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.1 0.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 1.0 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.2 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0035035 histone acetyltransferase binding(GO:0035035)