Motif ID: Hsf4

Z-value: 0.595


Transcription factors associated with Hsf4:

Gene SymbolEntrez IDGene Name
Hsf4 ENSMUSG00000033249.4 Hsf4



Activity profile for motif Hsf4.

activity profile for motif Hsf4


Sorted Z-values histogram for motif Hsf4

Sorted Z-values for motif Hsf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_71215779 1.659 ENSMUST00000034723.5
 Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr1_+_194938821 1.110 ENSMUST00000016638.2
ENSMUST00000110815.2
 Cd34

CD34 antigen

chr12_+_75308308 1.001 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr4_-_136892867 0.908 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr10_-_62507737 0.822 ENSMUST00000020271.6
 Srgn
serglycin
chr16_+_91225550 0.621 ENSMUST00000035608.8
 Olig2
oligodendrocyte transcription factor 2
chr7_-_110862944 0.601 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr12_-_110696332 0.581 ENSMUST00000094361.4
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr6_-_136941887 0.547 ENSMUST00000111891.1
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr8_-_71537402 0.537 ENSMUST00000051672.7
 Bst2
bone marrow stromal cell antigen 2
chrX_+_73214333 0.532 ENSMUST00000156188.1
ENSMUST00000069077.3
ENSMUST00000069103.4
ENSMUST00000114506.1
ENSMUST00000081827.3
 Xlr4b




X-linked lymphocyte-regulated 4B




chr6_-_136941494 0.509 ENSMUST00000111892.1
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr14_-_65833963 0.501 ENSMUST00000022613.9
 Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr12_-_110696289 0.500 ENSMUST00000021698.6
 Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr1_+_195017399 0.485 ENSMUST00000181273.1
 A330023F24Rik
RIKEN cDNA A330023F24 gene
chr13_-_111490111 0.475 ENSMUST00000047627.7
 Gpbp1
GC-rich promoter binding protein 1
chr11_+_82911253 0.474 ENSMUST00000164945.1
ENSMUST00000018989.7
 Unc45b

unc-45 homolog B (C. elegans)

chr9_-_13826946 0.469 ENSMUST00000147115.1
 Cep57
centrosomal protein 57
chr9_-_13827029 0.449 ENSMUST00000148086.1
ENSMUST00000034398.5
 Cep57

centrosomal protein 57

chr6_-_136941694 0.434 ENSMUST00000032344.5
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 107 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 1.7 GO:0035799 ureter maturation(GO:0035799)
0.3 1.5 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 1.3 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.4 1.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 1.0 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 1.0 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.9 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.3 0.8 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.8 GO:0034453 microtubule anchoring(GO:0034453)
0.2 0.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.6 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 0.5 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.5 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.1 0.5 GO:0042938 dipeptide transport(GO:0042938)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.4 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.1 0.4 GO:0019043 establishment of viral latency(GO:0019043)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)
0.3 1.3 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.2 GO:0046930 pore complex(GO:0046930)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.1 1.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.8 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.2 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.6 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 0.5 GO:0033503 HULC complex(GO:0033503)
0.1 0.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0000938 GARP complex(GO:0000938)
0.0 0.3 GO:0031428 box C/D snoRNP complex(GO:0031428)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.8 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.3 1.7 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 1.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:0042895 antibiotic transporter activity(GO:0042895)
0.0 0.5 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.4 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.4 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)