Motif ID: Nfia

Z-value: 2.350


Transcription factors associated with Nfia:

Gene SymbolEntrez IDGene Name
Nfia ENSMUSG00000028565.12 Nfia

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Nfiamm10_v2_chr4_+_97777606_977776320.301.7e-01Click!


Activity profile for motif Nfia.

activity profile for motif Nfia


Sorted Z-values histogram for motif Nfia

Sorted Z-values for motif Nfia



Network of associatons between targets according to the STRING database.



First level regulatory network of Nfia

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_20665250 28.018 ENSMUST00000075312.3
 Ttr
transthyretin
chr19_+_5740885 17.508 ENSMUST00000081496.5
 Ltbp3
latent transforming growth factor beta binding protein 3
chr6_+_141524379 16.334 ENSMUST00000032362.9
 Slco1c1
solute carrier organic anion transporter family, member 1c1
chr7_+_130936172 12.626 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr10_+_127725392 10.989 ENSMUST00000026466.3
 Tac2
tachykinin 2
chr4_+_48045144 10.470 ENSMUST00000030025.3
 Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr11_-_102897123 10.456 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr10_+_58813359 9.813 ENSMUST00000135526.2
ENSMUST00000153031.1
 Sh3rf3

SH3 domain containing ring finger 3

chr5_+_66968559 9.402 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1
chr13_-_97747373 9.313 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr7_-_97417730 9.283 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chr1_+_42229726 9.067 ENSMUST00000066196.1
 Gm9915
predicted gene 9915
chr2_-_25470031 8.774 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr5_+_66968416 8.748 ENSMUST00000038188.7
 Limch1
LIM and calponin homology domains 1
chr13_+_94173992 8.741 ENSMUST00000121618.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr11_+_78324200 8.719 ENSMUST00000102478.3
 Aldoc
aldolase C, fructose-bisphosphate
chr13_-_97747399 8.481 ENSMUST00000144993.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr2_-_25469742 8.474 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr11_-_102897146 8.251 ENSMUST00000077902.4
 Gfap
glial fibrillary acidic protein
chr3_+_89520152 8.216 ENSMUST00000000811.7
 Kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 388 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.8 33.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 21.7 GO:0031032 actomyosin structure organization(GO:0031032)
3.1 18.7 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
5.8 17.5 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
3.4 17.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.6 16.3 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.9 13.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.8 12.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
2.1 12.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 12.5 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
1.8 11.0 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.7 10.6 GO:0035994 response to muscle stretch(GO:0035994)
3.5 10.5 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095)
0.9 8.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.9 7.9 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.3 7.8 GO:0010043 response to zinc ion(GO:0010043)
0.3 7.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
2.5 7.4 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
1.2 7.3 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880) follicle-stimulating hormone secretion(GO:0046884)
1.4 7.2 GO:0060591 chondroblast differentiation(GO:0060591)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 171 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 67.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 26.6 GO:0005615 extracellular space(GO:0005615)
0.2 23.6 GO:0030175 filopodium(GO:0030175)
4.7 18.7 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 16.2 GO:0005925 focal adhesion(GO:0005925)
0.1 14.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 14.0 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 11.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 9.2 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 8.8 GO:0005667 transcription factor complex(GO:0005667)
2.4 7.3 GO:0043512 inhibin A complex(GO:0043512)
0.0 6.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 5.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
1.9 5.8 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 5.7 GO:0072562 blood microparticle(GO:0072562)
0.3 5.5 GO:0005614 interstitial matrix(GO:0005614)
0.2 5.4 GO:0005581 collagen trimer(GO:0005581)
0.1 5.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 5.2 GO:0005901 caveola(GO:0005901)
0.2 5.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 248 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.2 33.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 21.6 GO:0005178 integrin binding(GO:0005178)
0.8 17.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
4.3 17.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
4.1 16.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 14.8 GO:0003779 actin binding(GO:0003779)
0.0 14.7 GO:0005509 calcium ion binding(GO:0005509)
4.9 14.6 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.6 14.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 12.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
1.6 11.5 GO:0036122 BMP binding(GO:0036122)
0.1 11.3 GO:0000149 SNARE binding(GO:0000149)
1.5 8.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 8.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.3 8.2 GO:0042805 actinin binding(GO:0042805)
2.0 8.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 8.0 GO:0019838 growth factor binding(GO:0019838)
0.3 7.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
1.9 7.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.8 7.8 GO:0070700 BMP receptor binding(GO:0070700)